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Dewi Sondari
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Determination of The Active Asiaticoside Content in Centella asiatica as Anti-Cellulite Agent Sondari, Dewi; Harmami, Sri Budi; Ghozali, M; Randy, Ahmad; S, Athanasia Amanda; Irawan, Yan
Indonesian Journal of Cancer Chemoprevention Vol 2, No 2 (2011)
Publisher : Indonesian Research Gateway

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Abstract

Centella  asiatica  accumulates  large  quantities  of  pentacyclic  triterpenoid saponins,  collectively  known  as  centelloids.  These  terpenoids  include  asiaticoside, centelloside,  madecassoside,  brahmoside,  brahminoside,  thankuniside,  sceffoleoside, centellose, asiatic-, brahmic-, centellic- and madecassic acids. Preparations of C. asiatica are  used  in  traditional  and  alternative  medicine  due  to  the  wide  spectrum  of pharmacological  activities  associated  with  these  secondary  metabolites,  such  as anticellulite agent. Asiaticoside was found in Centella asiatica. In this present study, the asiaticoside was extracted using methanolic and ethanolic solvent. Determination of the asiaticoside  content  in  the  extract  was  conducted  with  High Performance  Liquid Chromatography (HPLC), Thin Layer Chromatography (TLC), and Fourier Transform Infra Red (FTIR). Samples of C.  asiatica used in this study came from three different plantation  areas,  Bogor,  Lembang  and  Solo.  Asiaticoside  content  in  the  methanolic extract  from  Bogor,  Lembang,  and  Solo  samples  were  2.82%;  2.68%;  and  2.8% respectively. Asiaticoside in ethanolic extract from Bogor, Lembang, and Solo samples were 2.79%; 2.75%; and 2.91% respectively. Two way ANOVA study showed that there was  significant  difference  between  types  of  solvent  used  in  extraction  and  the asiaticoside  content  in  the  obtained  extract,  significant  difference  between  varied plantation area and obtained asiaticoside content, and significant difference between interactions of different solvent with different plantation area.     Key words: Centella asiatica, asiaticoside, anticellulite, medicine, metabolites  
SISTESA NANOPARTIKEL PERAK DAN POTENSI APLIKASINYA Haryono, Agus; Sondari, Dewi; Harnami, Sri Budi; Randy, Muhammad
Jurnal Riset Industri Vol 2, No 3 (2008):
Publisher : Badan Penelitian dan Pengembangan Industri

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Abstract

Tulisan ini menuturkan beberapa metode sintesis nanopartikel perak yang sudah dilakukan. Salah satu metode sintesa nanopartikel perak yang dilakukan  adalah dengan metode reduksi kimia dari larutan perak nitrat potensi aplikasi nanopartikel perak antara lain sebagai katalis, detektor sensor optik dan agen antimikroba. Salahsatu apalikasi nanopartikel perak yang sudah banyak di pasarkan adalah produk dengan antimikroba. Karena produk komersial yang mengunakan nanopartikel perak sudahcukup beredar di pasaran , maka dilakukan kajian menyeluruh terhadap sisi keamanan terhadap kesehatan dan likungankata kunci :  nanopartikel perak, metode sintesa, aplikasi, agen antimikroba
MODIFIKASI KARET ALAM MENJADI BAHAN ELASTOMER TERMOPLASTIK Suhardjo, Kuntari Adi; Basuki, Ariyadi; ., Surasno; Randy, Ahmad; Sondari, Dewi
Jurnal Riset Industri Vol 5, No 3 (2011): Peningkatan Nilai Tambah dan Produktivitas Industri
Publisher : Badan Penelitian dan Pengembangan Industri

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Abstract

Karet alam  bersifat elastomer dan termoseting, sehingga sulit  untuk dibentuk dan tidak dapat didaur ulang., Modifikasi karet alam menjadi bahan elastomer termoplastik dimaksudkan untuk memperoleh bahan yang mudah dicetak  menjadi  produk  jadi   dan  dapat  dapat  didaur  ulang  sehingga  tidak  merusak  lingkungan.   Untuk mendapatkan teknologi pembuatan elastomer termoplastik dari karet alam  telah dilakukan percobaan  dengan metoda pencangkokan (grafting)   secara polimerisasi emulsi antara karet alam lateks dengan monomer stirena dan metil metakrilat. Polimerisasi emulsi dilakukan pada suhu 65°C selama 6 jam. Perbandingan komposisi karet alam lateks dan monomer di variasi:  80:20; 70:30; 60:40; 50:50 (% berat) dengan komposisi monomer stirena dan metil metakrilat   1:1, menggunakan dua jenis inisiator yaitu potassium persulfat 2 % berat atau ammonium peroksodisulfat divariasi 2, 2,5, 5 % berat serta emulsifier sodium dodesil sulfat divariasi: 0, 1, 1,5,  2, 5 % berat. Dari hasil analisa 1 H NMR dan FTIR terlihat bahwa proses cangkok monomer stirena dan metil metakrilat telah terjadi pada tulang punggung karet alam. Puncak pada frekuensi 833 cm -1 menunjukkan pita RzC=CHR, frekuensi 1743 dan 1519 cm-1menunjukkan pita C=O (gugus karbonil dari metil metakrilat) dan pita C=C (cincin benzena dari stirena). Efisiensi cangkok maksimum sebesar 97,60% diperoleh  pada komposisi 70% karet alam lateks dan 30% monomer dimana komposisi monomer antara stirena dan metil metakrilat adalah 1: 1 menggunakan inisiator potasium persulfat 2% dan emulsifier sodium dodesil sulfat 1%.Kata  kunci: Elastomer termoplastik, kopolimer cangkok, karet alam lateks, stirena, metilmetakrilat.
MODIFIKASI KARET ALAM MENJADI BAHAN ELASTOMER TERMOPLASTIK Suhardjo, Kuntari Adi; Basuki, Ariyadi; ., Surasno; Randy, Ahmad; Sondari, Dewi
Jurnal Riset Industri Vol 5, No 3 (2011): Peningkatan Nilai Tambah dan Produktivitas Industri
Publisher : Badan Penelitian dan Pengembangan Industri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (6742.063 KB)

Abstract

Karet alam  bersifat elastomer dan termoseting, sehingga sulit  untuk dibentuk dan tidak dapat didaur ulang., Modifikasi karet alam menjadi bahan elastomer termoplastik dimaksudkan untuk memperoleh bahan yang mudah dicetak  menjadi  produk  jadi   dan  dapat  dapat  didaur  ulang  sehingga  tidak  merusak  lingkungan.   Untuk mendapatkan teknologi pembuatan elastomer termoplastik dari karet alam  telah dilakukan percobaan  dengan metoda pencangkokan (grafting)   secara polimerisasi emulsi antara karet alam lateks dengan monomer stirena dan metil metakrilat. Polimerisasi emulsi dilakukan pada suhu 65°C selama 6 jam. Perbandingan komposisi karet alam lateks dan monomer di variasi:  80:20; 70:30; 60:40; 50:50 (% berat) dengan komposisi monomer stirena dan metil metakrilat   1:1, menggunakan dua jenis inisiator yaitu potassium persulfat 2 % berat atau ammonium peroksodisulfat divariasi 2, 2,5, 5 % berat serta emulsifier sodium dodesil sulfat divariasi: 0, 1, 1,5,  2, 5 % berat. Dari hasil analisa 1 H NMR dan FTIR terlihat bahwa proses cangkok monomer stirena dan metil metakrilat telah terjadi pada tulang punggung karet alam. Puncak pada frekuensi 833 cm -1 menunjukkan pita RzC=CHR, frekuensi 1743 dan 1519 cm-1menunjukkan pita C=O (gugus karbonil dari metil metakrilat) dan pita C=C (cincin benzena dari stirena). Efisiensi cangkok maksimum sebesar 97,60% diperoleh  pada komposisi 70% karet alam lateks dan 30% monomer dimana komposisi monomer antara stirena dan metil metakrilat adalah 1: 1 menggunakan inisiator potasium persulfat 2% dan emulsifier sodium dodesil sulfat 1%.Kata  kunci: Elastomer termoplastik, kopolimer cangkok, karet alam lateks, stirena, metilmetakrilat.
Formulation and Characteristics of Sunscreen Cream based on Isolated Lignin from Oil Palm Empty Fruit Bunch (OPEFB) : Formulation and Characteristics of Sunscreen Cream Restu, Witta Kartika; Rusumayanti, Felli; Septiyanti, Melati; Muryanto; Aryana, Nurhani; Mawarni, Rista Siti; Meliana, Yenny; Sondari, Dewi; Fatriasari, Widya; Ogino, Chiaki
Jurnal Sains Materi Indonesia Vol. 26 No. 2 (2025): Jurnal Sains dan Materi Indonesia
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jsmi.2025.6199

Abstract

Lignin was recovered from black liquor during the biorefinery process and has prospective applications in pharmaceutical, cosmetic, and health care. Lignin, which has substantially smaller particles, was used as the active ingredient in the sunscreen cream formulation. The isolated lignin was examined for physicochemical parameters such as yield, purity, particle size, total phenol, and morphology. The obtained lignin was used in the preparation of sunscreen cream. The isolated lignin concentration in the cream varied between 0.1, 1, and 2 wt%. The sun protection factor (SPF) of the designed sunscreen creams was assessed, and antioxidant activity and stability were studied, which included pH, particle size, and appearance during the observation period. The formulated cream has an SPF of approximately 15, which is sufficient to protect human skin from the sun's UV radiation. Furthermore, the most significant antioxidant activity was found to be 68.94%. As a result, the developed sunscreen cream has the potential for further research because it is composed of natural active ingredients that are safe for humans and the environment.
Pengaruh Enzim Amilase Brevibacterium sp dan Glukoamilase Terhadap Kemampuan Penjerapanan Minyak Pada Pati Singkong Uzwatania, Fina; Rahma, Putri Ajeng Syahru; Pramasari, Dwi Ajias; Ningrum, Riska Surya; Sondari, Dewi
Jurnal Teknologi Hasil Pertanian Vol 16, No 1 (2023): Februari
Publisher : Universitas Sebelas Maret (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jthp.v16i1.62318

Abstract

Improper oil waste management contributes to environmental degradation, notably water pollution. Because conventional methods for treating oil pollutants are costly and have limited removal efficacy, the use of natural adsorbents is recommended due to their dependability and affordability. The purpose of this study was to see how modified cassava starch affected oil adsorption using two types of enzymes: Brevibacterium sp amylase enzymes derived from Indonesian marine bacteria and commercial amylase enzyme (Dextrozyme® GA).Oil-adsorption degree is applied to several types of oil, including palm oil and olive oil. The findings revealed that the properties of modified starch differed from those of native starch in both physical and chemical terms. The modified starch produced by hydrolysis of the glucoamylase enzyme (Dextrozyme ® GA)had a yield of 80.16 %, reducing sugar content of 0.20 g/L at 24 h, and a particle size of 377 nm, which is lower than the starch hydrolyzed by Brevibacterium sp. In contrast, the degree of oil adsorption in the glucoamylase enzyme (Dextrozyme ® GA) is higher than Brevibacterium sp. Statistical analysis showed that the oil adsorption degree is affected by the type of enzyme, therefore, the modified starch from Brevibacterium sp still needs improvement to be competitive for oil adsorption compared with the modified starch from the glucoamylase enzyme (Dextrozyme ® GA).
Co-Authors AGUS HARYONO Ahmad Randy Ariyadi Basuki, Ariyadi Athanasia Amanda S Evi Triwulandari Fina Uzwatania M Ghozali Mawarni, Rista Siti Meliana, Yenny Muhammad Randy, Muhammad Muryanto Ningrum, Riska Surya Nurhani Aryana, Nurhani Ogino, Chiaki Pramasari, Dwi Ajias Rahma, Putri Ajeng Syahru Ridwanuloh, Asep Muhamad Rusumayanti, Felli Septiyanti, Melati Silvester Tursiloadi Sri Budi Harmami Sri Budi Harnami, Sri Budi Suhardjo, Kuntari Adi Surasno . Widya FATRIASARI Witta Kartika Restu Yan Irawan