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Novita Carolia
Universitas Lampung
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Journal : Medula

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THE CORRELATION BETWEEN ANTIBIOTIC SENSITIVITY AND OUTCOME OF SEPSIS PATIENTS IN INTENSIVE CARE UNIT (ICU) AT DR. H. ABDUL MOELOEK HOSPITAL LAMPUNG PROVINCE 2018-2021 Jaya Firmansyah; Ari Wahyuni; Maya Ganda Ratna; Novita Carolia
Medula Vol 12 No 2 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i2.393

Abstract

Sepsis is a life-threatening condition of organ dysfunction due to dysregulation of the host response to infection. Antibiotic therapy is the main treatment for sepsis patients. The high rate of antibiotic resistance in the community is a serious problem in sepsis therapy that affects patient outcomes. The objective was to determine the relationship between antibiotic sensitivity and the outcome of sepsis patients in intensive care unit (ICU) RSUD Dr. H. Abdul Moeloek Lampung Province 2018-2021. The design of this research was observational analytic with cross sectional approach. Total sampling technique was used. Analysis of the data used was chi square test. The characteristics of sepsis patients were male patients (51.1%), elderly age group (43.2%), respiratory tract infection (28.4%), patients with comorbidities (51.1%), and the patient recovered (51.1%). The antibiotic profile showed that the most widely used antibiotic was ceftriaxone (36.4%), frequency of administration ≤2 times (65.9%), duration of administration ≤7 days (76.1%), and sensitive antibiotics (59.1%). Bivariate analysis showed that there was a significant correlation between antibiotic sensitivity and outcome of sepsis patients in the intensive care unit (ICU) RSUD Dr. H. Abdul Moeloek Lampung Province in 2018-2021 with a p value of 0.01 (<0.05).
. Metode Gyssens Sebagai Pilihan Utama Dalam Evaluasi Kualitatif Penggunaan Antibiotik di Indonesia Dheti Efrilia -; Novita carolia; syazili mustofa; rasmi zakiah oktarlina
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.526

Abstract

Antibiotic resistance is a global health problem in the world. Antibiotic resistance is defined as the absence of inhibition of bacterial growth by systemic administration of antibiotics with normal doses or minimal inhibitory levels. The World Health Organization (WHO) seeks to control antibiotic resistance globally by making global action plans to combat bacterial resistance to antibiotics, namely increasing the wise use of antibiotics and evaluating the use of antibiotics. The qualitative evaluation that can be used is the Gyssens method. The Gyssens method was chosen because this method has more specific aspects to evaluate each of the important parameters included in the use of antibiotics such as indication, effectiveness, safety, price and spectrum, and can also evaluate treatment duration, dose, interval, and route of administration as well as time of giving. Therefore, this method is the main choice for evaluation of antibiotics in Indonesia.
Co-Authors agustyas tjiptaningrum Akhmad Rizki Farhan Ari Wahyuni Arif Yudho Prabowo Dheti Efrilia - Dian Isti Angraini Efriyan Imantika Evy Kurniawaty Fitria Saftarina Intanri Kurniati Jaya Firmansyah Letifa Rahmadani Maya Ganda Ratna Merry Indah Sari Mustofa Mustofa Ramadhana Komala Rasmi Zakiah Oktarlina Salsabila Dzakiyyah Zahra Sri Hasnawati Syazili Mustofa Winda Trijayanthi Utama, Winda Trijayanthi Zenith Puspitawati