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All Journal Jurnal Biosains Pascasarjana Indonesian Journal of Tropical and Infectious Disease Indonesian Applied Physics Letters Prosiding Seminar Nasional Unimus
Andi Hamim Zaidan
Department Of Physics, Faculty Of Science And Technology, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Earth & Planetary Sciences Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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Komposit Kolagen Fibril-Alginat Sebagai Kandidat Membran Hidrogel Skin Substitute Faiq Nadiatul Mardia Asa; Sri Sumarsih; Andi Hamim Zaidan
Jurnal Biosains Pascasarjana Vol. 18 No. 2 (2016): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (516.297 KB) | DOI: 10.20473/jbp.v18i2.2016.112-122

Abstract

AbstrakTelah dilakukan sintesis membran hidrogel komposit berbahan kolagen, alginat sebagai kandidat skin substitute. Tujuan dari penelitian ini adalah untuk mengetahui sifat fisikokimia dari membran hidrogel komposit kolagen-alginat. Metode yang dilakukan yaitu dengan teknik kering udarakan yang dicetak pada mika tipis selama tujuh hari pada suhu ruang. Hasil sintesis dikarakterisasi dengan PSA untuk mengetahui distribus ukuran nanopartikel perak, FTIR, penentuan morfologi dengan SEM, uji absorbsi dengan larutan PBS (Phospate Buffer Saline) uji kuat tarik, uji elongasi, uji sitotoksisitas dan uji antibakteri. Hasil analisis FT-IR pada membran memperlihatkan serapan kolagen dan alginat yang ditunjukkan dengan munculnya pergeseran pita serapan pada membrane komposit yaitu adanya Amida I dari kolagen, gugus karbonil (C=O) dari alginat. Hasil pengujian SEM membran komposit tanpa nanopartikel perak menunjukkan penebalan dinding dan pori yang lebar, sedangkan membran dengan penambahan nanopartikel perak ukuran pori lebih kecil. Berdasarkan hasil pengujian absorbsi menunjukkan semakin banyak komposisi kolagen pada membran maka semakin menurun lama membran hidrogel komposit menyerap larutan. Hasil pengujian kuat tarik menunjukkan nahwa semakin banyak komposisi kolagen pada membran hidrogel komposit maka semakin tinggi nilai kuat tariknya. Hasil uji elongasi menunjukkan semakin banyak komposisi kolagen maka semakin menurun nilai elongasinya.Kata kunci : membran hidrogel, kolagen, alginat
Synthesis and Characterization of Nickel-Based Superalloy Materials for Manufacturing Aircraft Turbine Blades Rezza Ruzuqi; Drs. Djony Izak Rudyardjo, M.Si.; Andi Hamim Zaidan, S.Si., M.Si., Ph.D.
Indonesian Applied Physics Letters Vol. 2 No. 2 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v2i2.31557

Abstract

The research has been conducted to manufacture nickel-based Superalloy materials. The purpose of this research was to find out the effects of variation of nickel composition on physical and mechanical properties of the Superalloy materials and find out the appropriate composition of Superalloy materials as materials for turbine blades. This research used nickel, cobalt, chromium, molybdenum, aluminium, and titanium commercial. The results showed that with more addition of nickel composition, the density and hardness values increased. This research showed that nickel-based Superalloy material 59 wt% was better applied as materials for turbine blades. It is also supported by the results of the test microstructure, where the structure of the sample morphology is more delicate and denser and contains smaller pores. Based on the XRD test results are also shown in the sample has been formed Superalloys phase.
Ab Initio Molecular Dynamic Study of Structural and Electrical Properties of Gold Nanoparticle Abdullah Aufa Fuad; Andi Hamim Zaidan; Adri Supardi
Indonesian Applied Physics Letters Vol. 3 No. 1 (2022): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v3i1.40259

Abstract

The goal of this research is to know structural and electrical properties of gold nanoparticle (GNP) through ab initio molecular dynamic (AIMD) method. Structural properties are explained by the study of coordination number, bond angle distribution, and radial distribution function. Electrical properties are explained by the study of band structure and density of states. GNP samples used in this research are liquid, amorph, and icosahedral. The main software used for AIMD numerical calculation was SIESTA. Liquid GNP is dominated by coordination number of 9, amorf GNP 10, icosahedral GNP 18. Bond angle distribution of liquid GNP has 1 peak in 60o, amorph GNP has 4 peak in 60o, 90o, 120o, 175o, icosahedral GNP has complete all 6 peak. Internal spacing of liquid GNP is 2,7 Ã…, amorph is 2,8 Ã…, icosahedral is 1,9 Ã…. Study of band structure show that the width of liquid GNP bandgap is 0,040 eV, amorph is 0,071 eV, icosahedral is 0,200 eV. While the width of bandgap by density of state study for liquid GNP is 0,053 eV, amorph is 0,085 eV, icosahedral is 0,200 eV.
PENGUATAN KARAKTER KEWIRAUSAHAAN SISWA SMK MELALUI PELATIHAN GREEN SINTESIS NANOPARTIKEL DARI EKSTRAK TUMBUHAN UNTUK TABIR SURYA Siswanto, Siswanto; Ady, Jan; Rudyardjo, Djony Izak; Hikmawati, Dyah; Aminatun, Aminatun; Zaidan, Andi Hamim; Samian, Samian; Supadi, Supadi; Firdaus, Indri K; Junico, Vallery Ofelia
Prosiding Seminar Nasional Unimus Vol 7 (2024): Transformasi Teknologi Menuju Indonesia Sehat dan Pencapaian Sustainable Development G
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pengabdian masyarakat di SMK ini bertujuan untuk memperkuat karakter kewirausahaan siswa melaluipelatihan berbasis inovasi teknologi, yakni green sintesis nanopartikel dari ekstrak tumbuhan untuk tabirsurya. Pelatihan ini dirancang untuk mengajarkan siswa teknik sintesis nanopartikel ramah lingkungan yangmemiliki aplikasi praktis dalam pembuatan produk kosmetik, khususnya tabir surya. Dalam kegiatan ini,peserta tidak hanya belajar tentang aspek teknis, tetapi juga tentang kewirausahaan dan potensi pasarproduk yang mereka buat. Evaluasi tingkat kepuasan peserta menggunakan Customer Satisfaction Index(CSI) menunjukkan nilai rerata sebesar 83,77%, mencerminkan kepuasan tinggi terhadap pelatihan yangdiberikan. Selain itu, terdapat peningkatan signifikan dalam pemahaman materi yang diukur melalui tespre-test dan post-test. Nilai pre-test peserta yang berada dalam rentang 20-60 meningkat menjadi 75-95pada post-test, menandakan efektivitas pelatihan dalam meningkatkan pengetahuan dan keterampilansiswa. Kegiatan ini tidak hanya memperluas wawasan siswa tentang teknologi nano dan keberlanjutan,tetapi juga memotivasi mereka untuk mengeksplorasi peluang kewirausahaan dalam bidang industrikosmetik. Dengan hasil ini, diharapkan siswa dapat lebih siap menghadapi tantangan industri serta memilikisikap kewirausahaan yang kuat Kata Kunci: SMK, Kewirausahaan, Nanopartikel, Green Sintesis, Tabir Surya
Red Laser-Activated Silver Nanoparticles from Green Synthesis Extract of Butterfly Pea for Antimicrobial Photodynamic Therapy Against Staphylococcus aureus Astuti, Suryani Dyah; Farhah, Ghinaa Rihadatul Aisy; Salwa, Umaimah Mitsalia Ummi; Aisya, Rohadatul; Zaidan, Andi Hamim; Yaqubi, Ahmad Khalil
Indonesian Journal of Tropical and Infectious Disease Vol. 12 No. 3 (2024)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v12i3.62884

Abstract

This study investigated the potential of photodynamic therapy (PDT) using green-synthesized silver nanoparticles (AgNPs) derived from butterfly pea extract (Clitoria ternatea L.) to combat Staphylococcus aureus (S. aureus). The use of a red diode laser as a method for enhancing the antimicrobial activity of AgNPs presents a novel approach to treating bacterial infections.  The red diode laser is crucial, as it activates the AgNPs, enhancing their antimicrobial properties. This combination of light, natural extract, and nanoparticles underscores the innovative approach of using PDT in treating bacterial infections. By integrating these elements, the study aims to provide insights into effective, biocompatible treatments for antibiotic-resistant bacteria.  The primary objective of this study is to synthesize and characterize AgNPs using butterfly pea extract and evaluate their effectiveness against S. aureus when combined with red laser irradiation.  Silver nanoparticles were synthesized using an environmentally friendly method that processes butterfly pea extract as the reducing agent for the synthesis of the nanoparticles.  Using UV-Vis spectrophotometry to track the creation of silver nanoparticles (AgNPs), it was determined that the butterfly pea extract was an effective source of nanoparticles. The particle size distribution and peak absorbance wavelength were determined by characterization utilizing a Particle Size Analyzer (PSA). Tryptic soy agar (TSA) plates were used to investigate the antibacterial activity of AgNPs against Staphylococcus aureus (S. aureus). The effectiveness of photoinactivation against S. aureus was evaluated by exposing AgNPs at a concentration of 1 mM to a red diode laser for 90 seconds. The results showed that the produced AgNPs had potential antibacterial capabilities when combined with red light therapy. The results demonstrated that the synthesized silver nanoparticles can effectively kill or inhibit the growth of Staphylococcus aureus (S. aureus) when exposed to a red diode laser for 90 seconds. The findings suggest that photodynamic therapy using green-synthesized AgNPs and red laser irradiation could be a promising approach to controlling bacterial infections like S. aureus. Further research is recommended to explore the underlying mechanisms of photoinactivation and to optimize treatment parameters for in vivo applications on experimental animals.
Co-Authors Abdullah Aufa Fuad Adri Supardi Aisya, Rohadatul Aminatun Aminatun Djony Izak Rudyardjo Faiq Nadiatul Mardia Asa Farhah, Ghinaa Rihadatul Aisy Firdaus, Indri K Jan Ady Junico, Vallery Ofelia Rezza Ruzuqi S Siswanto Salwa, Umaimah Mitsalia Ummi Samian Sri Sumarsih Supadi Supadi Suryani Dyah Astuti Yaqubi, Ahmad Khalil