Garuda - Garba Rujukan Digital

SPOROTRIKOSIS LIMFOKUTAN DIAGNOSIS HISTOPATOLOGI DAN SITOLOGI Lintong, Poppy M.; Sumolang, Inneke V.
JURNAL BIOMEDIK : JBM Vol 2, No 1 (2010): JURNAL BIOMEDIK : JBM
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.2.1.2010.843

Abstract: Diagnosis of sporotrichosis associated with lymphocutaneous nodules was made based on the histopathological examination of skin lesions and the cytology of fine needle aspiration biopsy (FNAB). A case of sporotrichosis in a 63-year-old man was reported with papules and nodules spread along the back of the left hand, forearm, and arm. The histopatho-logical examination showed infiltration of PMNs, granulomas, and giant cells in the dermis and epidermis, along with hyperplasia and microabscesses. Sporothrix schenckii was not found in the skin lesion tissues. However, in the FNAB cytology examination of lymphocutaneus nodules we found spores of Sporothrix schenckii in the cytoplasma of histiocytes besides granuloma and infiltration of PMNs. Key words: sporothrix schenckii, histopathology, FNAB cytology.Â Abstrak: Diagnosis sporotrikosis kulit dengan nodul limfokutan ditegakkan melalui pemerik-saan histopatologi pada lesi kulit dan sitologi biopsi aspirasi jarum halus pada nodul limfo-kutan. Kami melaporkan kasus sporotrikosis pada laki-laki berusia 63 tahun dengan papul-papul dan nodul-nodul eritematosa pada dorsum manus, antebrakium, dan brakium sinistra. Pemeriksaan histopatologi jaringan biopsi dari lesi kulit menunjukkan reaksi radang, gambaran granuloma, dan sel datia dalam dermis dan epidermis, dengan mikroabses disertai hiperplasia. Tidak ditemukan jamur Sporothrix schenckii dalam potongan jaringan histopatologi. Hasil pemeriksaan sitologi biopsi aspirasi jarum halus pada nodul limfokutan memperlihatkan adanya spora-spora jamur Sporothrix schenckii dalam sitoplasma sel-sel histiosit disampingÂ terdapatnya bentuk granuloma dalam infiltrat radang. Kata kunci: sporothrix schenckii, histopatologi, sitologi biopsi aspirasi jarum halus.

Pelatihan Pemeriksaan Kusta Pada Kader Posyandu Puskesmas Waena Kota Jayapura Inneke Vivi Sumolang; Astrina Rosaria Indah; William Hendrik Reba
MESTAKA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 2 (2024): April 2024
Publisher : Pakis Journal Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58184/mestaka.v3i2.194

Morbus Hansen (Leprae, Leprosy) is a chronic infection caused by Mycobacteria leprae (M.leprae) The disease affects the skin, the peripheral nerves and other organs. The rate of new cases of leprosy in Papua province is still high. There is a lack of public knowledge about the course of leprosy, if not treated immediately, can cause inflammation of the skin and nerves which worsened condition. Health cadres need to be trained about leprosy examination. Health cadres can detect leprosy at the nearest posyandu because leprosy is still an endemic disease in Papua. There were twenty-three participants who took part in leprosy examination training for posyandu cadres. The activity was carried out by presenting material about leprosy, discussion and simple procedures for examining leprosy which can be carried out by posyandu cadres.

Sindrom Hipersensitivitas Dapson pada Penderita Kusta di Kota Jayapura Papua Indonesia Tahun 2017-2019 Reba, Timothy V.P.; Arodes, Evy S.; Sumolang, Inneke V.; Pohan, Dame J.
Majalah Kedokteran UKI Vol. 37 No. 2 (2021): MEI - AGUSTUS
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mk.v37i2.4822

AbstrakPengendalian kusta saat ini berdasarkan pada deteksi dini kasus dan pengobatan dengan menggunakan rejimen multi drug therapy (MDT), salah satu komponen terapinya adalah dapson, sebagai antibiotika dan anti-inflamasi. Dapsone hypersensitivity syndrome (DHS) merupakan salah satu efek samping dapson. Tujuan penelitian ini untuk melihat profil DHS pada orang asli Papua penderita kusta di Puskesmas kota Jayapura. Terdapat 36 penderita DHS 34 (94,4%), yang asli orang Papua dan 2 (5,6%) penderita non Papua. Kelompok umur terbanyak pada usia 17-60 tahun berjumlah 26 (76,5%) penderita. Jenis kelamin terbanyak adalah perempuan sebanyak 18 (53%) penderita. Jenis kusta terbanyak adalah multibasiler (MB) sebanyak 31 (91,2%) penderita. Lama pemberian MDT sampai timbulnya gejala klinis DHS terbanyak adalah pada minggu ke-4 sebanyak 23 (67,6%) penderita. Gejala klinis yang paling sering muncul adalah demam, kulit mengelupas, sklera ikterik dan anemia yang didapatkan pada 31 (91,2%) penderita. Pemberian steroid sebagai pilihan terapi yang diberikan selama 36-40 hari diberikan pada 18 (53%) penderita, sedangkan terapi kurang 30 hari diberikan pada tiga (8,8%) penderita yang meninggal dunia. Kesimpulannya, DHS pada penelitian ini yang dilakukan di kota Jayapura ditemukan lebih banyak DHS pada orang Papua dibandingkan dengan non Papua. Gejala klinis terbanyak timbul pada minggu ke-4. Terapi yang diberikan adalah steroid dengan tapering off dengan waktu rata-rata sampai 40 hari.Kata Kunci: multibasiler, steroid, terapi AbstractThe control of leprosy is currently based on early detection of cases and treatment using the Multi Drug Therapy (MDT) regimen, one of the therapeutic components is dapsone, as an antibiotic and anti-inflammatory. Dapsone Hypersensitivity Syndrome (DHS) is a side effect of dapsone. The purpose of this study was to see the DHS profile of Papuans affected by leprosy at the Jayapura City Health Center. There were 36 DHS sufferers 34 (94.4%) of them were Papuans and 2 (5.6%) were non-Papuans. Most age groups aged 17-60 years were 26 (76.5%) sufferers. Most of the sexes were women as many as 18 (53%) sufferers. Most types of leprosy are multibacillary (MB) as many as 31 (91.2%) patients. The duration of MDT administration and the appearance of the most clinical symptoms of DHS at week 4 were 23 (67.6%) patients. The clinical symptoms that appeared most often were fever, peeling skin, scleral icterus and anemia were found in 31 (91.2%) patients. Steroid administration as a therapeutic option was mostly found for 36-40 days in 18 (53%) patients, while therapy for less than 30 days found 3 (8.8%) patients died. In conclusion, the DHS among Papuans in Jayapura city is higher than that of non-Papuans. Most clinical symptoms occur at week 4. The therapy given was steroids with tapering off with an average time of up to 40 days.Keywords: multibasiler, steroid, therapy

Skrining Frambusia Pada Anak Di Bawah 15 Tahun Di Perbatasan Jayapura Dengan Metode Rapid Diagnostic Test Sumolang, Inneke Viviane; Sidabutar, Astrina Rosaria Indah; Rusman, Nuraliah
Mestaka: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2025): Februari 2025
Publisher : Pakis Journal Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58184/mestaka.v4i1.488

Yaws is a tropical skin disease that can cause serious complications if left untreated. The border area between Indonesia and Papua New Guinea, especially in the Muara Tami district, Jayapura, Papua, is one of the endemic areas for yaws with limited access to health services. This community service activity aims to conduct early detection of yaws in children in the area using the rapid diagnostic test (RDT) method. The activity was carried out at the Moso Village Health Center, Muara Tami district. Samples were taken purposively, with the inclusion criteria being children under 15 years of age who live in Moso village. Yaws examination using RDT was carried out on 17 children, followed by treatment for those who tested positive. There were 4 positive cases of yaws or 23.52% detected from 17 participants who had received RDT examination. In addition, the achievement of this activity has educated parents of yaws screening participants about the symptoms and prevention of yaws so that it can increase the capacity of the local health system and public awareness in efforts to eliminate yaws. The prevalence of yaws in the border area is still quite high. The use of RDT has proven effective for the detection and monitoring of yaws, although there are still challenges in ensuring compliance and completion of treatment. Long-term monitoring is needed to evaluate the effectiveness of the intervention comprehensively.

THE DIAGNOSTIC TESTING OF YAWS USING THE RAPID DIAGNOSTIC TEST (RDT) METHOD IN THE BORDER AREA OF PAPUA NEW GUINEA AND PAPUA-JAYAPURA Sumolang, Inneke Viviane; Indah, Astrina Rosaria; Reba, Timothy Verellino; Nelson, Jefferson
Media Dermato-Venereologica Indonesiana Vol 52 No 2 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i2.556

Pendahuluan: Frambusia merupakan penyakit endemis treponematosis non-venereal yang disebabkan oleh infeksi bakteri Treponema pertenue. Penyakit ini adalah penyakit terabaikan dengan beban kesehatan kepada pasien dan masyarakat baik fisik, psikologik, dan ekonomi. Di Indonesia, lebih banyak ditemukan di Provinsi Nusa Tenggara Timur, Maluku, Sulawesi Tenggara, dan Papua. Tujuan dari penelitian ini adalah untuk mendapatkan gambaran diagnostik frambusia dengan metode rapid diagnostic test (RDT) di perbatasan Papua Nugini dan Papua-Jayapura tahun 2021-2022. Metode: Desain penelitian deskriptif dengan pemeriksaan darah kapiler serum pasien frambusia menggunakan rapid diagnostic test. Hasil: Pemeriksaan serologis terhadap 31 orang anak yang didiagnosis secara klinis sebagai frambusia memberikan hasil RDT positif sebesar 74,2% (26 anak). Gambaran karakteristik anak dengan RDT positif adalah 47% berusia 6-11 tahun, 65% berjenis kelamin laki-laki, dan sebanyak 73% lesi berlokasi di tungkai. Kesimpulan: Gambaran penelitian ini menjadi informasi penting untuk diagnostik cepat dan penanganan frambusia di daerah terpencil dengan keterbatasan akses ke fasilitas laboratorium.

A Distinctive Clinical Phenotype of Discoid Lupus Erythematosus in Papuanese Women: A 5-Year Analysis of Dyspigmentation, Scarring, and Malar Predilection Inneke Viviane Sumolang; Astrina Rosaria Indah; Timothy Verellino Reba; Aryani Adji; Paulus Mario Christopher
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 8 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i8.1358

Background: Discoid lupus erythematosus (DLE), the most common form of chronic cutaneous lupus, exhibits significant clinical variability influenced by ethnicity. While disparities in presentation are recognized, data from unique indigenous populations such as the Papuanese in East Indonesia remain scarce. This study aimed to characterize the clinical and sociodemographic features of DLE in this specific cohort to identify its potentially distinctive phenotype. Methods: A five-year retrospective analysis of clinical databases was conducted at the Department of Dermatology and Venereology at a tertiary referral hospital in Jayapura, Papua, Indonesia. All patients clinically diagnosed with DLE by board-certified dermatovenereologists between January 2019 and December 2023 were included. Sociodemographic and clinical data, including lesion morphology, location, and management, were systematically collected and analyzed using descriptive statistics. Results: A total of 22 patients meeting the criteria were identified. The cohort demonstrated remarkable homogeneity; all patients were of Papuanese ethnicity and female (100.0%). The majority were in the 26-35 age group (40.9%), with a mean age of 29.4 years, and half were farmers (50.0%). Clinically, lesions were universally present on the nose and/or malar area (100.0%). The most common morphological triad was dyspigmentation, scarring, and telangiectasia, observed in 81.8% of patients. All patients reported photosensitivity and were managed with photoprotection and topical steroids. Conclusion: DLE I n Papuanese women presents as a distinctive, highly uniform clinical phenotype characterized by an exclusive female predilection, a strong association with sun exposure, and a universal malar distribution with a high propensity for disfiguring dyspigmentation and scarring. These findings underscore the necessity of culturally competent, early, and aggressive management strategies to mitigate long-term sequelae in this vulnerable population.

A Distinctive Clinical Phenotype of Discoid Lupus Erythematosus in Papuanese Women: A 5-Year Analysis of Dyspigmentation, Scarring, and Malar Predilection Inneke Viviane Sumolang; Astrina Rosaria Indah; Timothy Verellino Reba; Aryani Adji; Paulus Mario Christopher
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 8 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i8.1358

Background: Discoid lupus erythematosus (DLE), the most common form of chronic cutaneous lupus, exhibits significant clinical variability influenced by ethnicity. While disparities in presentation are recognized, data from unique indigenous populations such as the Papuanese in East Indonesia remain scarce. This study aimed to characterize the clinical and sociodemographic features of DLE in this specific cohort to identify its potentially distinctive phenotype. Methods: A five-year retrospective analysis of clinical databases was conducted at the Department of Dermatology and Venereology at a tertiary referral hospital in Jayapura, Papua, Indonesia. All patients clinically diagnosed with DLE by board-certified dermatovenereologists between January 2019 and December 2023 were included. Sociodemographic and clinical data, including lesion morphology, location, and management, were systematically collected and analyzed using descriptive statistics. Results: A total of 22 patients meeting the criteria were identified. The cohort demonstrated remarkable homogeneity; all patients were of Papuanese ethnicity and female (100.0%). The majority were in the 26-35 age group (40.9%), with a mean age of 29.4 years, and half were farmers (50.0%). Clinically, lesions were universally present on the nose and/or malar area (100.0%). The most common morphological triad was dyspigmentation, scarring, and telangiectasia, observed in 81.8% of patients. All patients reported photosensitivity and were managed with photoprotection and topical steroids. Conclusion: DLE I n Papuanese women presents as a distinctive, highly uniform clinical phenotype characterized by an exclusive female predilection, a strong association with sun exposure, and a universal malar distribution with a high propensity for disfiguring dyspigmentation and scarring. These findings underscore the necessity of culturally competent, early, and aggressive management strategies to mitigate long-term sequelae in this vulnerable population.

Profile of Leprosy Among Children in Jayapura City Sumolang, Inneke V.; Indah, Astrina Rosaria; Reba, Timothy V. P
International Journal of Public Health Excellence (IJPHE) Vol. 2 No. 2 (2023): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v2i2.1474

Leprosy is a chronic infectious disease caused by Mycobacterium leprae with highly variable clinical presentations. Leprosy remains a health problem in Indonesia. Leprosy cases in children are an epidemiological index to determine disease transmission as an indicator of the success of the national leprosy eradication program. Objective: To analyze the picture of leprosy in children in Jayapura City. A retrospective study method was used to examine all new leprosy cases in children (0-14 years) in all community health centers in Jayapura City who came to the Community Health Center Outpatient Unit from January 2019 to December 2022. The results of this study revealed that of the 967 new leprosy cases, 811 (83.87%) were adults and 156 (16.13%) were children aged 0-14. The most common age group was 10-14 years with 96 people (61.54%). Male gender was 82 people (52.56%) and female gender was 74 people (47.44%). In general, there were 103 Papuans (66.03%), while 53 non-Papuans (33.97%) had multibacillary leprosy. 128 (82.05%) had paucibacillary leprosy, and 28 (17.95%) had paucibacillary leprosy. Twenty-three (14.75%) of the children with leprosy dropped out. The leprosy rate among children in Jayapura City remains very high, at around 16.13%.

Skrining Dan Intervensi Gizi Buruk Pada Anak di Kampung Waena Indah, Astrina Rosari; Sumolang, Inneke Viviane; Rahayu, Agnes Supraptiwi; Rusman, Nuraliah
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 6 No. 3 (2025): Edisi Juli - September
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v6i3.7044

Permasalahan gizi buruk pada anak masih menjadi tantangan di berbagai wilayah, termasuk di Kampung Waena. Berdasarkan observasi awal, banyak anak mengalami kurang gizi akibat keterbatasan akses terhadap makanan bergizi dan rendahnya kesadaran orang tua mengenai pola makan sehat. Skrining dan intervensi gizi menjadi langkah penting untuk mendeteksi secara dini status gizi anak dan mencegah dampak jangka panjang seperti gangguan tumbuh kembang dan risiko penyakit kronis di masa depan. Program pengabdian ini bertujuan untuk mengidentifikasi anak-anak dengan risiko gizi buruk, memberikan intervensi berupa edukasi dan pemberian makanan tambahan (PMT). Pelaksanaan kegiatan akan dilakukan pada 26 Mei 2025 di Kampung waena dengan melibatkan berbagai pihak seperti akademisi, tenaga kesehatan, dan masyarakat setempat. Metode yang diterapkan meliputi pengukuran antropometri, edukasi gizi berbasis bahan pangan lokal, serta intervensi terhadap anak yang mempunyai status gizi buruk dan stunting. Pemeriksaan antropometri dilakukan terhadap 36 peserta. Peserta terdiri atas 20 perempuan dan 16 laki-laki. Status gizi Indeks Masa Tubuh berdasarkan umur didapatkan 6 % gizi buruk. Status gizi tinggi badan berdasarkan umur didapatkan 25 % memiliki tinggi badan dibawah normal (stunting). Hasil kegiatan pengabdian adalah skrining gizi buruk di Kampung Waena dan tindak lanjut intervensi pemberian makanan tambahan berupa tinggi protein hewani dan tinggi kalsium.

TOWARD INDONESIA’S ZERO LEPROSY 2030: KEY LESSONS FROM EPIDEMIOLOGICAL TRENDS IN PAPUA 2020-2024 Sumolang, Inneke Viviane; Romadhon, Dimas Iqbal; Suyanto, Agnes Angelita
Folia Medica Indonesiana Vol. 61, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Papua, the easternmost province of Indonesia, has consistently reported the highest number of new leprosy cases and leprosy-related disabilities for decades. Despite this burden, no comprehensive study in recent years has systematically examined the epidemiological trends of leprosy in Papua using large datasets. This study provides an updated analysis of leprosy elimination efforts and evaluates the province’s readiness to achieve the Zero Leprosy 2030 target. A retrospective descriptive epidemiological review was conducted using secondary data from the routine health information system of Papua Province from 2020 to 2024. Extracted variables included demographic characteristics, new case reports, diagnostic classification, disability grade, case-finding method, and clinical outcomes. Data were analyzed descriptively and presented in tables and figures to illustrate temporal trends. Between 2020 and 2024, a total of 3,909 new leprosy cases were reported, with fluctuating case detection rates. Multibacillary (MB) leprosy predominated, particularly among males, although females also contributed a substantial proportion of MB cases. Child cases showed an increasing trend, accounting for up to 20% of all new cases. Most cases were detected at Grade 0, with passive case finding as the dominant detection method. Treatment outcomes showed that approximately 70% of patients were released from treatment annually, but relapse and default remained considerable. These findings highlight that Papua is still far from reaching the Zero Leprosy 2030 goal. Strengthening active case finding, improving treatment adherence, reducing stigma, and enhancing reporting and evaluation systems are urgent priorities. Sustained political commitment from local leadership will be crucial to ensure the successful implementation of these strategies.

Title

Found 10 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 10 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 10 Documents
Search