Garuda - Garba Rujukan Digital

Malnutrition-Inflammation Score (MIS) and Physical Activity among Hemodialysis Patients in Dr. Hasan Sadikin General Hospital Bandung Rizka Putri Hamuktiono; Rudi Supriyadi; Nida Suraya
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (588.192 KB)

Background: Protein Energy Malnutrition (PEM) related to inflammation and physical activities reduction occur commonly among hemodialysis patients. This study aimed to describe Malnutrition-Inflammation Score (MIS) and physical activity of hemodialysis patients.Methods: This study involved 117 patients in the Hemodialysis Unit of Dr. Hasan Sadikin General Hospital Bandung from September to October 2014. Secondary data were collected to examine MIS and physical activity, which was measured by using Baecke Physical Activity Questionnaire. The collected data were presented using frequency distribution.Results: Eighty (68.4%) patients had MIS <6, thirty seven (31.6%) patients had MIS ≥6, and ninety four (80.3%) patients had light physical activity.Conclusions: Most of the patients have MIS <6 and are physically inactive. [AMJ.2015;2(4):601–7] DOI: 10.15850/amj.v2n4.478

Cardiovascular-Related Death Risk Factors in Hypertensive Patients: Indonesia Family Life Survey 2000-2014 Rudi Supriyadi; David Paranoan; Yulia Sofiatin
International Journal of Integrated Health Sciences Vol 9, No 1 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v9n1.2185

Objective: To determine the characteristics of the risk factors of cardiovascular death in hypertensive patients in Indonesia based on the Indonesian Family Life Survey (IFLS) longitudinal data. Methods: This was a retrospective descriptive study on secondary data from the IFLS population starting from2000 and was followed up in 2007 and 2014. The inclusion criteria for participation were15 years old or older, had hypertension, had cardiovascular events as thecause of death, and had complete data in both IFLS 3 (2000) and IFLS 4 (2007).Results: The IFLS 5 (2014) reported 918 deaths among eligible subjects with complete data, both in IFLS 3 (2000) and IFLS 4 (2007). Of those, a total of 608 subjects experienced hypertension started from 2000 and/or 2007. Of these deaths, 112 were due to cardiovascular events. Cardiovascular death was more common in males (58.9%), age of >65 years old when died (47.3%), had poor socioeconomic status (24.1%), and with normal body mass index (54.9%).Conclusion: Male, late adulthood, low level of education, normal BMI, and poor socioeconomic status represented the greater risks of cardiovascular death among hypertensive patients in Indonesia.

Effectiveness of Erythropoietin in Hypertensive Hemodialysis Patients Susannia Ibrahim; Ajeng Diantini; Budhi Prihartanto; Rudi Supriyadi
Pharmacology and Clinical Pharmacy Research Vol 2, No 2
Publisher : Universitas Padjadjaran, Indonesia

Chronic renal failure (CRF) is one the most prevalent health problems among the elderly. Onthe fifth stage of CRF, the patient becomes eligible to hemodialysis. CRF-induced anemiais commonly treated with Erythropoietin (Epo). Information regarding the effectiveness ofEpo in hypertensive hemodialysis patients was limited. Therefore, this study was conductedto evaluate the effectiveness of Epo in hypertensive hemodialysis patients. This study usedan observational case-control analytic method. Data were retrieved from the medical recordsof hemodialysis patients during March-May 2014. A total of 54 participants were included.The increase of haemoglobin (Hb) in controlled hypertension was 0.6257 g/dl, while the inuncontrolled hypertension group, there was a decrease in Hb (-0.1590 g/dl). The use of Epowas more effective in hemodialysis patients with controlled hypertension.Keywords: chronic kidney disease, erythropoietin, hypertension

Sarcoidosis Manifested as Recurrent Pericardial Effusion with Signs of Impending Tamponade Christine Elizabeth Suryajaya; Susantina Prodjosoewojo; Arto Y. Soeroto; Nuraini Yasmin Kusumawardhani; Rudi Supriyadi; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 13 No. 2 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i2.200

Pericardial effusion is a fatal and life-threatening condition. If it is not addressed thoroughly, complications such as constrictive pericarditis may occur. Etiologies of pericardial effusion varied and one of the most common etiologies is tuberculosis. Other etiologies include inflammation, malignancy or other autoimmune disorder such as sarcoidosis. Sarcoidosis is a diagnosis of exclusion and is confirmed by biopsy result that showed non-caseating epitheloid-cell granuloma, with no other organism or particles. Epidemiology of sarcoidosis in Japan is 1-2 case per 100.000 patients, with the peak incidence between the age of 20 to 39 years old. We reported a case of 37 years old woman presented to our emergency department with shortness of breath and signs of pericardial tamponade. She was previously healthy with no other significant past medical. She was first treated as a case of extrapulmonary tuberculosis and shown no improvement with anti-tuberculosis medications. Several work ups were then done in search of other etiologies of her pericardial effusion. A biopsy form one of her abdominal lymph nodes was performed, which pathologically revealed sarcoidosis. She was placed on corticosteroid and methotrexate with improvement of symptoms. One month followed up showed complete resolution of her pericardial effusion.

Reduction of Liver Fibrosis After Treatment with Elbasvir/Grazoprevir in Patients with Hepatitis C Infection in Chronic Kidney Disease on Hemodialysis, a Quasi-Experimental Study Bayu Laksono; Nenny Agustanti; Rudi Supriyadi; Muhammad Begawan Bestari; Siti Aminah Abdurachman
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 1 (2021): VOLUME 22, NUMBER 1, April 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Background: Approximately 5-60% of hemodialysis patients have comorbid of hepatitis C virus (HCV) infection. The survival rate of hemodialysis patients HCV is lower than those without HCV due to the risk of liver fibrosis and cardiovascular disease. The combination of Elbasvir and Grazoprevir is the drug of choice for these patients with HCV genotype 1 and 4 which mainly inherited in populations in Indonesia. However, a high cost is required for this genome testing. Eradication of HCV might reduce liver fibrosis. One of the methods to evaluate liver fibrosis is by using APRI score. The aim of this study is to assess liver fibrosis using APRI score after Elbasvir/Grazoprevir therapy completion.Method: This was a quasi-experimental study without a control group which conducted during April-November 2019 in Dr. Hasan Sadikin Hospital, Bandung. Patients with reactive anti HCV, detected HCV RNA without genotype test, and sustained virological response (SVR) 12 achieved were included. APRI score and HCV RNA tests were performed before and after 12 weeks end of therapy (SVR12). The data were analyzed using paired T-test at a 95% confidence level.Results: Approximately 30% of hemodialysis patients had HCV infection. A total of 37 HCV patients in the hemodialysis unit were given Elbasvir/Grazoprevir for 12 weeks. The APRI score before and after 12 weeks after therapy were 0.336 and 0.270 (p = 0.002) respectively.Conclusion: The combination of Elbasvir/Grazoprevir might reduce the degree of liver fibrosis based on APRI score from 0.336 to 0.270 in HCV patients with chronic kidney disease on hemodialysis

Laporan Kasus: Tantangan Pengelolaan Krisis Hiperglikemia Pasien Penyakit Ginjal Kronik (PGK) Tahap Akhir dalam Hemodialisa Rutin Davin Takaryanto; Maya Kusumawati; Nenny Agustanti; Rudi Supriyadi; Ervita Ritonga; Nanny N. M. Soetedjo; Hikmat Permana
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar

Introduction Hyperglycemic crisis is a life threatening medical emergency which occur in any individuals, including end stage renal disease (ESRD). The altered renal, glucose, electrolyte, and body fluid dysregulation seen in ESRD patients affects the management. Objective: Hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) are life threatening hyperglycemic emergencies that warrant immediate and adequate management. The incidence of hyperglycemic crises among ESRD patients who undergo routine hemodialysis remains unknown. Furthermore, several available studies reported in case reports. Methods: We hereby report a case of hyperglycemic crisis of 61years old woman with medical history of type 2 diabetes mellitus (DM) and ESRD as the complication, she undergoes routine hemodialysis. Results: The patient was admitted with decreased consciousness that was preceded by dyspnea, active cough and fever. Then, the patient treated for the hyperglycemic crisis as in ESRD patient and for the with septic shock due to pneumonia. Conclusion: The management of hyperglycemic crises consist of fluid, potasium corection and insulin administration, however there were some adjustment in ESRD patients. At present therere were no spesific guidelines to manage hyperglicemic crisis and ESRD which is challenging.

Pengaruh Edukasi Personal Secara Langsung Terhadap Pengetahuan Masyarakat Mengenai Penyakit Ginjal Kronik Nida Dwi Nafisah; Rudi Supriyadi; Yenni Zuhairini
Jurnal Sistem Kesehatan Vol 6, No 2 (2021): Volume 6 Nomor 2 Desember 2021
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jsk.v6i2.48525

Edukasi berhubungan dengan perubahan pengetahuan, sikap, dan perilaku masyarakat. Tingkat pengetahuan masyarakat memengaruhi tingkat kesadaran untuk melakukan deteksi dini. Penelitian ini bertujuan untuk mengetahui pengetahuan dan pengaruh edukasi terhadap peningkatan pengetahuan masyarakat mengenai penyakit ginjal kronik. Studi analitik komparatif dilakukan pada 70 data pre dan post tes dengan edukasi personal langsung mengenai ginjal dan penyakit ginjal kronik. Subjek penelitian adalah masyarakat Jawa Barat yang merupakan peserta acara World Kidney Day 2019, berusia ≥ 18 tahun, tidak memiliki riwayat penyakit ginjal, dan tidak berprofesi sebagai tenaga kesehatan. Pertanyaan terdiri dari 24 soal dan dikelompokan menjadi 6. Data dianalisis dengan menggunakan Kruskal Wallis, Mann Whitney, dan Wilcoxon Signed Rank test. Hasil penelitian menunjukan bahwa tidak terdapat perbedaan nilai yang bermakna antara responden dengan perbedaan jenis kelamin (p=0.223), usia (p=0,553), tingkat pendidikan (p=0,709), adanya riwayat diabetes (p=0,087) dan hipertensi (p=0,292). Jawaban yang paling banyak benar ialah mengenai pencegahan penyakit ginjal kronik dengan mengonsumsi asupan cairan yang cukup (pre tes=90.0%; post tes=95.7%). Secara keseluruhan, nilai pre tes berbeda bermakna dengan nilai post tes (median pre tes=14.50; median post tes=19.00, p<0,001). Simpulan penelitian adalah terdapat pengaruh edukasi personal secara langsung terhadap peningkatan pengetahuan masyarakat mengenai penyakit ginjal kronik.Kata Kunci : Edukasi, Pengetahuan, Penyakit Ginjal Kronik

Laporan Kasus: Tantangan Pengelolaan Krisis Hiperglikemia Pasien Penyakit Ginjal Kronik (PGK) Tahap Akhir dalam Hemodialisa Rutin Davin Takaryanto; Maya Kusumawati; Nenny Agustanti; Rudi Supriyadi; Ervita Ritonga; Nanny N. M. Soetedjo; Hikmat Permana
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v2i1.2800

Introduction Hyperglycemic crisis is a life threatening medical emergency which occur in any individuals, including end stage renal disease (ESRD). The altered renal, glucose, electrolyte, and body fluid dysregulation seen in ESRD patients affects the management. Objective: Hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) are life threatening hyperglycemic emergencies that warrant immediate and adequate management. The incidence of hyperglycemic crises among ESRD patients who undergo routine hemodialysis remains unknown. Furthermore, several available studies reported in case reports. Methods: We hereby report a case of hyperglycemic crisis of 61years old woman with medical history of type 2 diabetes mellitus (DM) and ESRD as the complication, she undergoes routine hemodialysis. Results: The patient was admitted with decreased consciousness that was preceded by dyspnea, active cough and fever. Then, the patient treated for the hyperglycemic crisis as in ESRD patient and for the with septic shock due to pneumonia. Conclusion: The management of hyperglycemic crises consist of fluid, potasium corection and insulin administration, however there were some adjustment in ESRD patients. At present therere were no spesific guidelines to manage hyperglicemic crisis and ESRD which is challenging.

Prevalence and Factors Associated with Sarcopenia in Chronic Kidney Disease Patients Undergoing Dialysis: A Single Center, Cross-sectional Study Rakhima, Fauliza; Bandiara, Ria; Supriyadi, Rudi; Dwipa, Lazuardhi
Indonesian Journal of Kidney and Hypertension Vol 2 No 1 (2025): Volume 2 No. 1, April 2025
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v2i1.180

Background: Sarcopenia is associated with worse outcomes in stage 5 Chronic Kidney Disease on dialysis (CKD 5D) patients, influenced by various diagnostic criteria and patient characteristics. Nonetheless, the factors contributing to sarcopenia in CKD 5D remain underexplored. Objective: To investigate the prevalence and factors associated with sarcopenia in the CKD 5D population. Methods: An observational cross-sectional study was conducted on 132 CKD 5D patients (≥18 years old, dialysis ≥ 3 months) at Hasan Sadikin Hospital from July to August 2024. Descriptive statistics, bivariate analysis, and logistic regression were utilized to determine the prevalence of sarcopenia and its association with the Simplify Creatinine Index (SCI), physical activity, nutritional status, phosphate, and calcium serum levels. Hand Grip Strength (HGS) assessed muscle strength, Bioelectrical Impedance Spectroscopy (BIS) measured muscle mass, the 6-meter walk test evaluated physical performance, and the Asian Working Group for Sarcopenia (AWGS) 2019 criteria were employed for diagnosing sarcopenia. Results: Sarcopenia prevalence was 15.9%. Bivariate analysis revealed significant correlations with underweight (p=0.014), malnutrition (p=0.041), phosphate serum level (p=0.047), and calcium serum level (p=0.043). Logistic regression indicated that higher serum levels of calcium and phosphate and healthy nutritional status, served as protective factors against sarcopenia, with odds ratios of 0.677 (OR 0.677; CI 95% 0.493-0.93 and OR 0.313; CI 95% 0.130-0.755). Conclusion: Sarcopenia prevalence was 15.9%. Phosphate and calcium serum levels, underweight, and malnutrition were significantly correlated with sarcopenia. Higher serum phosphate and calcium levels, higher body weight, and good nutrition status were protective factors against sarcopenia in CKD 5D patients.

Nutriepigenetic Modulation of Hypertension Risk: A Review of the Literature Iryaningrum, Maria Riastuti; Soetedjo, Nanny Natalia Mulyani; Indraswari, Noormarina; Supriyadi, Rudi
Indonesian Journal of Global Health Research Vol 7 No 2 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i2.4774

This review aimed to investigate the interplay between dietary components and epigenetic modulation in the pathogenesis of hypertension. A comprehensive literature search encompassing all published primary and secondary research dating up to March 2024 was carried out on several electronic databases, including MEDLINE, EBSCO-Host, Science Direct, ProQuest, and Google Scholar. Individual genomes and dietary intake exhibit a bidirectional relationship, influencing the hypertension risk. Unhealthy dietary patterns can compromise DNA integrity through DNA methylation and histone acetylation, ultimately affecting both systolic and diastolic blood pressure. Dietary macronutrient composition (carbohydrates, lipids, and proteins) significantly alters the expression of specific microRNAs (miRNAs) known to regulate endothelial function and blood pressure homeostasis. Moreover, micronutrients (vitamin A, D, E, Zinc, Iodine, and Sodium) can exert epigenetic effects on blood pressure via receptor interactions, potentially modifying cardiovascular disease risk. Dietary imbalances in macro and micronutrients can epigenetically influence hypertension development. Addressing these deficiencies through targeted interventions may offer a complementary approach to hypertension treatment.

Title

Found 20 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 20 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 20 Documents
Search