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All Journal International Journal of Public Health Science (IJPHS) Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Sari Pediatri Paediatrica Indonesiana Berita Kedokteran Masyarakat Indonesian Journal of Biomedicine and Clinical Sciences
Suryono Yudha Patria
Department Of Pediatrics, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Central Java
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Linear growth and systemic glucocorticoid therapy in children with systemic lupus erythematosus Dikahayu Alifia Anugrah; Suryono Yudha Patria; Cahya Dewi Satria
Paediatrica Indonesiana Vol 62 No 1 (2022): January 2022
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi62.1.2022.37-43

Abstract

Background The use of long-term oral glucocorticoid therapy, specifically in the treatment of systemic lupus erythematosus (SLE), has increased in the past two decades. Chronic glucocorticoid use may lead to a linear growth disturbances. Objective To determine the association between linear growth and systemic glucocorticoid therapy in pediatric SLE patients. Methods This retrospective cohort study used medical record data of pediatric SLE patients. All subjects received systemic glucocorticoids. The linear growth parameters recorded in this study were height-for-age z-score (HAZ) and height velocity at 0, 6, and 12 months of treatment. We recorded potential risk factors of linear growth disturbance, such as pubertal status, sex, SLE severity, pulse methylprednisolone use, daily glucocorticoid dose, and nutritional status. Results Of 42 patients with SLE, 83.3% were female, with a mean age of 13 years at diagnosis. Eighteen subjects (42.9%) experienced abnormal height velocity. There was a significant reduction in HAZ between 0, 6, and 12 months of treatment (P=0.016). Between 0 and 6 months of treatment, there was a mean HAZ decrease of 0.11 (P=0.015). There was a trend towards a risk for decreased HAZ at 6 and 12 months of treatment with pulse methylprednisolone (RR 1.25 and 1.27, respectively), as well as for abnormal height velocity (RR 1.73), but they did not reach statistical significance. Conclusion There is a reduction in linear growth in the first 12 months of systemic glucocorticoid therapy in children with SLE. Administration of systemic glucocorticoid significantly reduced HAZ in the first six months of therapy.
Faktor individu dalam prediksi diabetes mellitus tipe 2 di Salatiga Jawa Tengah Priscila Evangelin Asa; Dibyo Pramono; Suryono Yudha Patria
Berita Kedokteran Masyarakat (BKM) Vol 33, No 2 (2017)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.252 KB) | DOI: 10.22146/bkm.12598

Abstract

Individual factors as predictors of diabetes mellitus in SalatigaPurposeThe purpose of this study was to determine the relationship of the individual factors with the incidence of diabetes mellitus in Salatiga.MethodsThe research was a case control study conducted from April to June 2016 around the existing health centers in the Salatiga. The total sample was 156 respondents. Data analysis used McNemar’s Chi-square and multiple logistic regression conditional tests.ResultsThe variables associated with the incidence of diabetes mellitus was a family history of diabetes. People who have a family history of diabetes have a risk 41 times more likely to develop diabetes mellitus compared with people who do not have a family history of diabetes mellitus in Salatiga.ConclusionThis study concluded that the incidence of diabetes mellitus is affected by family history. Primary health care is expected to cooperate with health office to conduct prevention efforts such as activities that encourage physical activity.
Incidence of congenital hypothyroidism in special region of Yogyakarta in 2018-2020 Sabella Rahmawati, Rhea; Ratnaningsih, Tri; Windarwati, Windarwati; Yudha Patria, Suryono
International Journal of Public Health Science (IJPHS) Vol 13, No 4: December 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i4.24091

Abstract

Congenital hypothyroidism (CH) is an inadequate thyroid hormone in newborns and is one of the most common causes of preventable mental retardation. It is crucial to do CH screening in newborns aged a few days to detect early occurrences of CH so that intervention can be done immediately. Screening for CH was introduced in Indonesia in 2000, and by 2014, the percentage of newborns screened remained less than 1% of the total. The Special Region of Yogyakarta, one of Indonesia's provinces, has not been the subject of any research regarding the incidence of CH. Hence, this study aimed to investigate the incidence of CH in the Special Region of Yogyakarta during the period from 2018 to 2020. This study, conducted from January 2018 to December 2020, investigated CH incidence in Yogyakarta using data from 23,787 screened newborns. Nine were diagnosed with primary CH. Incidence of CH in this study was higher in males than females, small for gestational age (SGA) than appropriate for gestational age (AGA), and preterm than term, with no significant differences between the variables and CH incidence. Therefore, the incidence in the Special Region of Yogyakarta in 2018-2020 was found to be 1:2,643.
Health comorbidities in children with down syndrome (DS) at Dr. Sardjito General Hospital, Yogyakarta Suryono Yudha Patria; Agung Triono
Indonesian Journal of Biomedicine and Clinical Sciences Vol 56 No 3 (2024)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v56i3.16062

Abstract

Down syndrome (DS) is a disease caused by trisomy of chromosome 21. The phenotype in DS leads to manifestations in several organ systems. This study aimed to identify the pattern of comorbidities in DS patients. It was a single-center, cross-sectional study at Dr. Sardjito General Hospital, Yogyakarta. Medical records of pediatric patients with DS from a period of January 2022 to May 2023 were included. Descriptive analysis was performed to demonstrate demographic and clinical characteristics. A total of 355 pediatric patients with DS were found at Dr. Sardjito General Hospital and the majority were male (196 children or 55.2%). As much as 339 children (95.49%) had comorbidities. The highest comorbidity was congenital heart disease (230 patients or 67.84%) in specifics were atrial septal defect (41 patients or 12.39%), atrioventricular septal defect (29 patients or 8.17%), and patent ductus arteriosus (28 patients or 7.88%). The second highest comorbidity was endocrine system disorders (102 patients or 30.09%), with 100 patients (28.16%) children suffering hypothyroidism. The number of children who had one comorbidity was 248 patients (69.86%), 74 patients (20.48%) had two comorbidities, and 17 patients (4.79%) had three or more comorbidities. The highest co-prevalence of the two comorbidities was congenital heart disease and endocrine system disorders (36 patients or 10.14%). The highest co-prevalence of 3 or more comorbidities was a combination of congenital heart disease, visual impairment, and hearing impairment (6 patients or 1.69%). In conclusion, 95.49% of children with DS have comorbidities. The most common comorbidity was heart defects. About 25.63% of patients had more than one comorbidity. Children with DS who have comorbidities require more attention to prevent complications and to reduce morbidity.
Undetected Takayasu arteritis presenting as severe hypertension in children: a report of two cases Wirawan, Muhammad Taufik; Murni, Indah Kartika; Patria, Suryono Yudha; Arafuri, Nadya; Noormanto, Noormanto; Nugroho, Sasmito
Paediatrica Indonesiana Vol 64 No 5 (2024): September 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.5.2024.454-8

Abstract

Takayasu arteritis (TA) is a rare chronic granulomatous vasculitis mainly affecting the aorta and its main branches. Clinical presentations of TA are non-specific, especially in the initial phase, which likely contributes to delayed diagnosis besides the rarity of the disorder. Childhood-onset of TA is associated with significant morbidity and mortality. This case report aimed to present two rare cases of acute symptomatic severe hypertension in children due to TA.
Co-Authors Agung Triono Cahya Dewi Satria Dibyo Pramono Dikahayu Alifia Anugrah Din Alfina Elisabeth Siti Herini Hajime Nakamura Indah Kartika Murni Ita Fauzia Hanoum Listianingrum Listianingrum Madarina Julia Muhammad Buchori Muriana Novariani Nadya Arafuri Noormanto Noormanto, Noormanto Priscila Evangelin Asa Pudjo Hagung Widjajanto Retno Sutomo Rini Anggraini Sabella Rahmawati, Rhea Sasmito Nugroho, Sasmito Sunartini Hapsara Tri Ratnaningsih Tunjung Wibowo Tunjung Wibowo Windarwati, Windarwati Wirawan, Muhammad Taufik