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Gustini Syahbirin
Departemen Kimia, Fakultas MIPA, Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Engineering Environmental Science Industrial & Manufacturing Engineering Materials Science & Nanotechnology Physics Veterinary

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Journal : Makara Journal of Science

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PVA-Sansevieria trifasciata Fraction Films as Absorbers of Electromagnetic and Thermal Radiation on Smartphones Rahmani, Nabiila; Syahbirin, Gustini; Maddu, Akhiruddin; Sugita, Purwantiningsih; Ilmiawati, Auliya
Makara Journal of Science Vol. 27, No. 1
Publisher : UI Scholars Hub

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Technological developments have prompted the production of highly advanced smartphones. However, various advanced features cause smartphones to heat up quickly and emit more electromagnetic radiation, which harms human health. Smartphone protection is needed to solve these issues. This study aims to create a film from the S. trifasciata plant based on polyvinyl alcohol (PVA) to reduce electromagnetic and thermal radiation on smartphones. S. trifasciata plants were macerated with acetone and partitioned with n-hexane, dichloromethane, ethyl acetate, and water. The films were made by mixing PVA with the four fractions. Among the four layers of film, the PVA + water and PVA + ethyl acetate fractions reduced electromagnetic radiation by 25.34% and 2.64%, respectively, and smartphone heat by 3.82 °C and 2.8 °C, respectively, the largest reductions. The results of an LC–MS/MS analysis show that the compounds thought to be contained in both fractions and play a major role in reducing electromagnetic and thermal radiation in smartphones are di-(2-ethylhexyl) phthalate, diisononyl phthalate, and two steroidal compounds, namely, stigmasterol and ergosterol peroxide.
Suspension Stability and Characterization of Chitosan Nanoparticle–Coated Ketoprofen Based on Surfactants Oleic Acid and Poloxamer 188 Rasyid, Nur Qadri; Sugita, Purwantiningsih; Ambarsari, Laksmi; Syahbirin, Gustini
Makara Journal of Science Vol. 18, No. 3
Publisher : UI Scholars Hub

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In this research, ketoprofen was used as a drug model in the preparation of chitosan nanoparticles as a potential drug delivery system through the ionic gelation process with tripolyphosphate (TPP). The particle size analysis (PSA) revealed that the average particle size, polydispersity index (PI), and entrapment efficiency of chitosan nanoparticles prepared with oleic acid were 253.7 nm and 0.375 with drug entrapment efficiency of 73.30%. Those prepared with poloxamer 188 were 242.94 nm and 0.302 with drug entrapment efficiency of 87.89%. Scanning electron microscopy (SEM) analysis showed that the shapes of the nanoparticles, both prepared with oleic acid and poloxamer 188, were intact and spherical. Fourier transform infrared spectroscopy (FTIR) indicated several differences between the spectra of chitosan- and ketoprofen-loaded chitosan nanoparticles; for example, a new peak at the wavenumber 1409/cm indicated the presence of electrostatic interaction between the carboxyl group of ketoprofen and the amino group of chitosan. The chitosan nanoparticle suspension prepared with poloxamer 188 showed smaller increases in turbidity and viscosity than that prepared with oleic acid after 34 d of storage.
Co-Authors Abdul Aziz Darwis Aditianingrum, Kurnia Alysia Akhiruddin Maddu Ani Suryani Ani Suryani Auliya Ilmiawati Azkiyah, Dina Budi Arifin DADANG DADANG EKA CHANDRA LINA Firdayani, Firdayani Fitri, Iis Yusma Komar Sutriah Kurniawanti, Kurniawanti Kusdiantoro Mohamad LAKSMI AMBARSARI Muhamad Alif Hamimdal Nur Qadri Rasyid Pajri Samsi Nasution Purwantiningsih Sugita Rahmani, Nabiila Rasyid, Nur Qadri Shabrina Shabrina Sri Mulijani Syafrida Manuwoto Tesar Dzikrulloh Wasrin Syafii