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All Journal Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan JMM (Jurnal Masyarakat Mandiri) JFIOnline SANITAS: Jurnal Teknologi dan Seni Kesehatan Abdimasku : Jurnal Pengabdian Masyarakat Jurnal Pengabdian kepada Masyarakat Journal of Innovation Research and Knowledge
Kristanty, Ruth Elenora
Poltekkes Kemenkes Jakarta II
Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Aktivitas Antioksidan dan Penghambat Xantin Oksidase dari Ekstrak Buah Andaliman (Zanthoxylum acanthopodium DC.) Kristanty, Ruth Elenora; Mun'im, Abdul; Katrin, .
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 6, No 3 (2013)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.683 KB)

Abstract

The fruits of andaliman (Zanthoxylum acanthopodium DC.) are well known in North Sumatera and commonly used as seasoning for Batak traditional cuisine. Aims of this study were to determine the scavenging activity of free radicals and xanthine oxidase inhibitory activity from the andaliman fruit extracts after macerated garually in petroleum ether, dichloromethane, ethyl acetate, n-butanol, and methanol. Activity assay were evaluated in vitro by using DPPH and enzyme xanthine oxidase. The result showed that n-butanol extract has medium antioxidant activity with IC50 values of 53.51 μg/mL and methanol extract has strong antioxidant activity with IC50 values of 26.39 mg/mL. Xanthine oxidase inhibitory activity of the extract given by n-butanol and methanol are very strong with IC50 values of 3.69 μg/mL and 4.03 μg/mL. Keywords : antioxidant, free radical, xanthine oxidase, Zanthoxylum acanthopodium DC.  
AKTIVITAS ANTIJERAWAT DARI LOTION LENDIR BEKICOT (ACHATINA FULICA) Ristiawati, Nita; Kristanty, Ruth Elenora
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5521.153 KB) | DOI: 10.35617/jfi.v9i1.554

Abstract

ABSTRAK : Lendir bekicot (Achatina fulica) dalam bentuk lotion telah diuji secara ilmiah aktivitasnya terhadap bakteri penyebab infeksi jerawat. Penelitian bertujuan menghasilkan formula lotion lendir bekicot yang bisa mengobati jerawat. Metode pengujian antibakteri menggunakan turbidimetri. Evaluasi sediaan yang dilakukan meliputi pengamatan organoleptik dan pH, ujidaya sebar dan uji daya lekat. Berdasarkan hasil pengujian yang telah dilakukan, lendir bekicot dan lotion lendir bekicot memiliki aktivitas antibakteri terhadap Propionibacterium acnes. Lotion lendir bekicot yang menghasilkan efek anti jerawat paling baik adalah yang mengandung konsentrasi lendir 16%. Sediaan lotion memiliki karakteristik, daya sebar, dan daya rekat yang baik. Bentuk sediaan stabil dalam penyimpanan suhu kamar selama lima minggu.
Aktivitas Antioksidan dan Penghambat Xantin Oksidase dari Ekstrak Buah Andaliman (Zanthoxylum acanthopodium DC.) Kristanty, Ruth Elenora; Mun'im, Abdul; Katrin, .
Jurnal Farmasi Indonesia Vol 6, No 3 (2013)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.683 KB) | DOI: 10.35617/jfi.v6i3.133

Abstract

The fruits of andaliman (Zanthoxylum acanthopodium DC.) are well known in North Sumatera and commonly used as seasoning for Batak traditional cuisine. Aims of this study were to determine the scavenging activity of free radicals and xanthine oxidase inhibitory activity from the andaliman fruit extracts after macerated garually in petroleum ether, dichloromethane, ethyl acetate, n-butanol, and methanol. Activity assay were evaluated in vitro by using DPPH and enzyme xanthine oxidase. The result showed that n-butanol extract has medium antioxidant activity with IC50 values of 53.51 μg/mL and methanol extract has strong antioxidant activity with IC50 values of 26.39 mg/mL. Xanthine oxidase inhibitory activity of the extract given by n-butanol and methanol are very strong with IC50 values of 3.69 μg/mL and 4.03 μg/mL. Keywords : antioxidant, free radical, xanthine oxidase, Zanthoxylum acanthopodium DC.  
Co-Authors . Katrin Adin Hakim Kurniawan Junaedi Junaedi Marsigit, Didik Mun'im, Abdul Mun'im, Abdul Nashrul Hakiem Priyanto Dwi Nugroho Purnama Fajri Ristiawati, Nita Saputra, Atang Sarah Sitorus Sugeng Wiyono Sugeng Wiyono Suriawati, Junie Susy Syarifah Miftahul El Jannah Yusmaniar Yusmaniar