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All Journal Jurnal Gizi dan Pangan JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro Journal of Nutrition College Majalah Kedokteran Bandung Bioscientist : Jurnal Ilmiah Biologi

Kusmiyati Tjahjono

Program Studi Ilmu Gizi Fakultas Kedokteran Universitas Diponegoro

Author-ID : 404100

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Social Sciences

Published : 11 Documents Claim Missing Document

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Kadar seng dan kadar malondialdehyde pada penderita multi drug resistant tuberculosis dan tuberkulosis sensitif Suparno, Suparno; Suhartono, Suhartono; Sofro, Muchlis Achsan Udji; Sulchan, Mohammad; Tjahjono, Kusmiyati
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 1 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Zinc is the main constituent element of Superoxide Dismutase (SOD) which acts to protect cells from inflammation and the toxic effects of Reactive Oxygen Species (ROS). High ROS production induces fat peroxidation, and forms malondialdehyde (MDA) which causes oxidative stress.Objectives: This study aimed to analyze the difference of zinc and malondialdehyde levels among Multi Drug Resistant Tuberculosis and sensitive Tuberculosis.Methods: Crossectional study with 55 subjects consisted of 32 MDR-TB subjects and 23 subjects TB sensitive. Selection of subjects using consecutive sampling. Zinc and MDA serum was obtained from venous blood. Zinc and MDA concentration were assessed by quantitative colometric and Thiobarbituric Acid Reactive Substances (TBARS) respectively. Data were analized statistic by independent t-test and Mann Whitney test.Results: Zinc level of MDR-TB and TB sensitive were 74.85 (64 - 97) Î¼g/dl and 73.03 (63 - 97) Î¼g/dl respectively, while MDA of MDR-TB and sensitive TB were 2.262Â±1.055 nmol/mL and 2.66Â±0.992 nmol/mL. There was no significantly different in zinc level between MDR-TB and sensitive TB (p=1.000). Furthermore, there was not significantly different of MDA level between MDR-TB and sensitive Tuberculosis (p=0,147).Conclusion: There are no differences in zinc and MDA levels in patient between MDR-TB and sensitive TB.

Sensitivitas dan spesifisitas lingkar pergelangan tangan sebagai prediktor obesitas dan resistensi insulin pada remaja akhir Fitriyanti, Addina Rizky; Tjahjono, Kusmiyati; Sulchan, Mohammad; Sunarto, Sunarto
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 2 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Obesity is one of the risk factors for insulin resistance. Insulin resistance plays an important role in the pathogenesis of cardiovascular disease. Wrist circumference has the potential for predicting obesity and insulin resistance.Objectives:. To evaluate the sensitivity and specificity of wrist circumference against obesity and insulin resistance in late adolescents.Methods: The design of this study is a crossectional study with a sample of 85 students at Diponegoro University Semarang. Data collected consisted of anthropometric measurements (body weight, height, wrist circumference, neck circumference, waist circumference and pelvic girth) and blood vein sampling (fasting blood glucose and fasting insulin). Statistical analyses used in this study were Pearson or R Spearman correlation test.Results: Wrist circumference was positively correlated with all biochemical parameters and anthropometric measurements except the waist hip ratio. Wrist circumference correlates positively and significantly with fasting insulin and HOMA-IR in male adolescents. The results of the ROC curve analysis showed that the AUC value of wrist circumference in male adolescents had better performance in predicting obesity (88% (95% CI, 76% - 100%)) than insulin resistance (81% (95% CI, 51% -100%)).Conclusion: Wrist circumference is one of the anthropometric measurements that can be used for predicting obesity and insulin resistance in late adolescents.

Pengaruh pemberian minuman lidah buaya terhadap kadar antioksidan total dan persentase lemak tubuh pada sindrom metabolik Silitonga, Marisi Elizabeth R.; Nugroho HS, K. Heri; Tjahjono, Kusmiyati; Widyastiti, Nyoman Suci; Afifah, Diana Nur
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 1 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Metabolic syndrome is related to glucose metabolism disturbance (hyperglycemia), lipid (dyslipidemia), high blood pressure, and central obesity. Metabolic syndrome implicates to heart attack, diabetes mellitus, hypertension, and death. Aloe vera, well known rich of polyphenol and vitamin, has a pharmacological effect to improve insulin resistance, chronic inflammation, and oxidative stress.Objective: To prove the effect of Aloe vera-based drink toward total antioxidant concentration improvement and body fat percentage reduction in metabolic syndrome subjects.Methods: Thus study was pre-post randomized true experimental study with control group design. The subjects were divided by 2 groups, treatment group (n=19) and control group (n=19). Treatment group was given 165 g/d Aloe vera-based drink for 30 days. Both of groups were given nutrition education about metabolic syndrome management. Total antioxidant concentration and body fat percentage were assessed pre-post-test by ABTS and BIA respectively, while food intake and activity were assessed by 24-h recall and GPAQ respectively. Independent t-test and Mann Whitney test were used to compare before and after treatment between control and treatment group.Results: Total antioxidant concentration significantly improved (p=0.00) in treatment group from 1.2 to 2.0 mmol/L, while total antioxidant concentration decreased from 1.4 to 1.3 mmol/L (p=0.074) in this control group. Moreover, there was significant difference of total antioxidant between treatment and control groups in the end of study (p=0.00). Furthermore, body fat percentage was reduced significantly from 32.8 to 32,4 mmol/L (p=0.005) in treatment group, while the reduction of body fat percentage in control group was not significant from 33.1 to 33,4 mmol/L (p=0.100). There was no difference of body fat percentage between two groups after intervention (p=0.358).Conclusion: Aloe vera-based drink improved total antioxidant concentration in metabolic syndrome subjects.

Association of food consumption and physical activity with metabolic syndrome according to central obesity status in Indonesian adults: A cross-sectional study Permatasari, Mayang Januarti; Syauqy, Ahmad; Noer, Etika Ratna; Pramono, Adriyan; Tjahjono, Kusmiyati
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 12, No 1 (2023): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.12.1.31-35

Background: Previous studies have reported that the risk of metabolic syndrome differs between obese and non-obese individuals based on food consumption and physical activity.Objective: This study aims to analyze differences in the association of food consumption and physical activity with the incidence of metabolic syndrome in individuals with and without central obesity.Materials and Methods: This cross-sectional study examined individuals aged 19 to 64 years using Riskesdas 2018 data. Sample characteristics, including smoking habits, alcohol consumption, food consumption, physical activity, anthropometric data, clinical data, and biochemical data were collected for univariate, bivariate, and multivariate analyses. Logistic regression was used as a multivariate analysis to investigate the association of food consumption and physical activity with the risk of metabolic syndrome in individuals with and without central obesity. Results: In this study, individuals with and without central obesity significantly increased risk of metabolic syndrome (p<0.05) due to consuming nearly all kinds of unhealthy foods (sweet foods, savory foods, fatty/cholesterol-rich/fried foods, grilled foods, processed meat/chicken/fish, soft drinks/carbonated drinks, energy drinks, and instant noodles/other instant foods). However, only individuals without central obesity who frequently consume seasonings (OR=1.519, 95% CI: 1.241-1.859) have a significant association with an increased risk of metabolic syndrome. Meanwhile, only individuals with central obesity who often consume sugary drinks (OR=1.315, 95% CI: 1.132-1.529) are significantly associated with an increased risk of metabolic syndrome. In addition, inadequate consumption of fruits and vegetables as well as lack of physical activity also significantly increase the risk of metabolic syndrome in individuals with and without central obesity (p<0.05).Conclusion: Only the consumption of seasonings and sugary drinks shows a different relationship to the risk of metabolic syndrome in individuals with and without central obesity.

Co-Authors Adriyan Pramono Ahmad Syauqy Anak Agung Gede Sugianthara Awal Prasetyo Budiarto, Andika Agus Cut Arsyiyanti Diana Nur Afifah, Diana Nur Djuara P Lubis Etika Ratna Noer Fitriyanti, Addina Rizky Hesti Murwani R Joyeti Darni K. Heri Nugroho HS, K. Heri Larasati Sekar Kinasih Martha Irene Kartasurya Mohammad Sulchan Muchlis Achsan Udji Sofro Muhammad Sulchan Neny Meirindasari Nyoman Suci Widyastiti Permatasari, Mayang Januarti Putri, Stella Andriana Rahmawati, Nesti Riva Mustika Anugrah Shabrina, Nadine Nurani Siahaan, Johanna Silitonga, Marisi Elizabeth R. Sunarto Sunarto Suparno Suparno Wibowo, Alem Pramudita

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