Article Per Year (5 Year)
p-Index From 2020 - 2025
2.727
P-Index
This Author published in this journals
All Journal JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro Medical Journal of Indonesia Jurnal Keolahragaan Journal of Biomedicine and Translational Research The Indonesian Biomedical Journal Paediatrica Indonesiana JOURNAL SPORT AREA Journal of Biology Education Media Medika Muda Journal of Dedicators Community Medica Hospitalia Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Cendana Medical Journal
Nyoman Suci Widyastiti
Department Of Clinical Pathology, Faculty Of Medicine, Diponegoro University, Semarang
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 32 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 32 Documents
Search

 1   2   3   4 
Melatonin menurunkan berat badan tetapi tidak menurunkan kadar TNF-α pada tikus wistar jantan yang diberi minyak jelantah selama 28 hari Novianti, Anugrah; Dharmana, Edi; Widyastiti, Nyoman Suci
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 2 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (442.997 KB) | DOI: 10.14710/jgi.5.2.127-132

Abstract

Backgound: Non Alcoholic Fatty Liver Disease (NAFLD) occurs when the intake and free fatty acid synthesis occurs more frequently than its oxidation and resecretion in the blood. Melatonin is a powerful antioxidant that can boost the synthesis of endogenous antioxidants in the body, suppress the inflammatory response and inhibit the formation of steatosis.Objective: To analyze the effect of melatonin supplementation in reducing body weight andTNF-α levels in male Wistar rats were fed by waste cooking oil.Methods: True experimental studyusing post-test only control group design. This study was done on 18 male wistar rats were divided into 3 groups : the positive control group (P0) was administrated waste cooking oil, the treated group 1 (P1) was administrated waste cooking oil and 5mg/kgBW melatonin, and the treated group 2 (P2) was administrated waste cooking oil and 10mg/kgBW melatonin for 28 days.Data analysis using One Way ANOVA test and followed by Tukey test to determine the most effective dose of melatonin.Results: There was significant difference in body weightbetween P2group and K0 group (p=0,019) with the mean body weight difference was 19,167g lower than K0 group. There was no difference in TNF-α levels between the three groups (p=0,155). Conclusion: Melatonin dose of 10mg/kgBWloses body weight male Wistar rats have given by waste cooking oil for 28 days, but does not reduce TNF-α levels.
Pengaruh suplementasi vitamin e (α-tokoferol) terhadap kadar gamma glutamil transferase (ggt) dan kadar nitric oxide (no) pada tikus (Studi pada tikus rattus novergicus strain wistar jantan terpapar inhalasi uap benzene) Roziana, Roziana; Subagio, Hertanto Wahyu; Suhartono, Suhartono; Widyastiti, Nyoman Suci
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 2 (2015)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (687.835 KB) | DOI: 10.14710/jgi.3.2.73-79

Abstract

Latar Belakang : Paparan benzene dapat menyebabkan stres oksidatif, diantaranya ditandai dengan peningkatan kadar GGT dan kadar NO. Vitamin E dapat mengurangi dan mencegah produksi radikal bebas. Reaktivitas hidrogen fenolik pada kelompok hidroksil α-tokoferol akan menstabilkan elektron tidak berpasangan pada radikal bebas.Tujuan : Membuktikan pengaruh suplementasi vitamin E terhadap kadar GGT dan kadar NO pada tikus jantan terpapar uap benzene.Metode : Penelitian ini adalah penelitian eksperimen pada binatang coba dengan rancangan post test only controlled group design. Sampel 35 ekor tikus strain wistar jantan dibagi secara random dalam enam kelompok yaitu kontrol negatif, kontrol positif dan empat kelompok perlakuan suplementasi vitamin E dosis bertingkat (X1 = 1,8 IU;  X2 = 3,6 IU; X3 = 7,2 IU; dan X4 = 14,4 IU per hari untuk setiap 200 gram berat badan tikus). Setiap kelompok kecuali kontrol negatif dipapar 300 ppm uap benzene selama 2 minggu (6 hari/minggu, 6 jam/hari). Pengukuran kadar GGT menggunakan metoda Kinetik Colorimetric dan kadar NO menggunakan metoda Colorimetric Gries dilakukan pada setiap kelompok. Hasil : Suplementasi vitamin E berpengaruh menurunkan  kadar GGT (p=0,0001). Pengaruh paparan benzene terhadap peningkatan kadar GGT dapat dicegah dengan baik pada dosis suplementasi vitamin E 14,4 IU/200gr BB tikus/hari. Suplementasi vitamin E tidak berpengaruh terhadap kadar NO.Simpulan : Ada pengaruh suplementasi vitamin E terhadap penurunan kadar GGT dan  tidak ada pengaruh suplementasi vitamin E terhadap penurunan kadar NO.
Pengaruh pemberian minuman lidah buaya terhadap kadar antioksidan total dan persentase lemak tubuh pada sindrom metabolik Silitonga, Marisi Elizabeth R.; Nugroho HS, K. Heri; Tjahjono, Kusmiyati; Widyastiti, Nyoman Suci; Afifah, Diana Nur
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 1 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (478.798 KB) | DOI: 10.14710/jgi.7.1.1-8

Abstract

Background: Metabolic syndrome is related to glucose metabolism disturbance (hyperglycemia), lipid (dyslipidemia), high blood pressure, and central obesity. Metabolic syndrome implicates to heart attack, diabetes mellitus, hypertension, and death. Aloe vera, well known rich of polyphenol and vitamin, has a pharmacological effect to improve insulin resistance, chronic inflammation, and oxidative stress.Objective: To prove the effect of Aloe vera-based drink toward total antioxidant concentration improvement and body fat percentage reduction in metabolic syndrome subjects.Methods: Thus study was pre-post randomized true experimental study with control group design. The subjects were divided by 2 groups, treatment group (n=19) and control group (n=19). Treatment group was given 165 g/d Aloe vera-based drink for 30 days. Both of groups were given nutrition education about metabolic syndrome management. Total antioxidant concentration and body fat percentage were assessed pre-post-test by ABTS and BIA respectively, while food intake and activity were assessed by 24-h recall and GPAQ respectively. Independent t-test and Mann Whitney test were used to compare before and after treatment between control and treatment group.Results: Total antioxidant concentration significantly improved (p=0.00) in treatment group from 1.2 to 2.0 mmol/L, while total antioxidant concentration decreased from 1.4 to 1.3 mmol/L (p=0.074) in this control group. Moreover, there was significant difference of total antioxidant between treatment and control groups in the end of study (p=0.00). Furthermore, body fat percentage was reduced significantly from 32.8 to 32,4 mmol/L (p=0.005) in treatment group, while the reduction of body fat percentage in control group was not significant from 33.1 to 33,4 mmol/L (p=0.100). There was no difference of body fat percentage between two groups after intervention (p=0.358).Conclusion: Aloe vera-based drink improved total antioxidant concentration in metabolic syndrome subjects.
THE RELATION BETWEEN TYPES OF IRON CHELATORS AND FERITIN ON OSTEOCALCIN OF THALASSEMIA PATIENTS WITH REPEATED TRANSFUSIONS Amelia, Sesa; Nugroho, Trilaksana; Widyastiti, Nyoman Suci; Kholis, Fathur Nur
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (427.715 KB) | DOI: 10.14710/dmj.v9i1.26565

Abstract

Introduction:  Thalassemia is an inherited disorder that decrease the rate of globin synthesis. Multiple blood transfusions in thalassemia patients leading to complications of hemosiderosis and hemochromatosis. Iron chelator aims to remove excess iron in the body. High ferritin levels interfere with 25-hydroxyvitamin-D production and negatively affect bone metabolism, measured with osteocalcin (N-Mid Oc). Study aims to determine the relation between type of iron chelator and ferritin levels to osteocalcin levels in thalassemia patients with history of repeated transfusions. Method: An observational analytic cross-sectional study. Research was conducted in May - August 2019 and carried out at Red Cross Semarang, Rembang Hospital, and Purwodadi Hospital. Study subjects were 40 people, then 6 people were excluded to 34 people. Gender are 14 male and 20 female. Subjects were thalassemia patient with repeated transfusions and undergoing iron chelation therapy. Subjects that met the criteria were tested for blood to measure ferritin levels and osteocalcin levels. Results: Average ferritin levels was 2842.85 ug/L and average osteocalcin levels was 15.05 ng/mL. There was significant relation between type of iron chelator on osteocalcin levels (p=0.046), but there was no significant relation between type of iron chelator on ferritin levels (p=0.434). There was significant relation between ferritin levels and osteocalcin levels on patient with Deferasirox therapy (p=0.022), but no significant relation on patient with Deferiprone therapy (p=0.432). Conclusion: There is significant relation between the type of iron chelator on osteocalcin levels and there is significant relation between ferritin levels and osteocalcin levels on patient with Deferasirox therapy.Keywords: thalassemia,iron chelator, deferasirox, deferiprone, ferritin, osteocalcin
Pengaruh suplementasi β-carotene terhadap kadar glukosa darah dan kadar malondialdehida pada tikus sprague dawley yang diinduksi Streptozotocin Soviana, Elida; Rachmawati, Banundari; Widyastiti, Nyoman Suci
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 2, No 2 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (502.768 KB) | DOI: 10.14710/jgi.2.2.41-46

Abstract

Background : Hyperglycemia on diabetes mellitus can cause increasing of free radicals production. Free radicals caused lipid peroxidation reaction by forming malondialdehyde (MDA). β-carotene has antioxidant activity may inhibit the formation of ROS.Objective : To prove the effect of multilevel doses β-carotene 1 mg/kg BW, 20 mg/kg BW and 20 mg/kg BW on alternate days within 30 days orally supplementation on blood glucose level and MDA level on Sprague Dawley male rats induced by streptozotocin (STZ). Methods : Thirty rats were randomly divided into 5 groups: X1=Negative control/diabetic, X2 (STZ 40 mg/kg BW + BC 1 mg/kg BW), X3 (STZ 40 mg/kg BW + BC 10mg/kg BW), X4 (STZ 40 mg/kg BW + BC 20 mg/kg BW), X5 (technic control/non diabetic). β-Carotene supplementation was given by nasogastric tube on alternate days within thirty days. Blood glucose level was measured by GOD-PAP and MDA level by ELISA with TBARS methods. Data was analized using paired t-test, wilcoxon, one way anova and post hoc bonferroni. Results : there was a significant difference of blood glucose level (p = 0,0001) and MDA level (p = 0,0001) after suplementation β-carotene on alternate days within 30 days orally. β-carotene 10 mg/kg BW was the most effective and efficient dose to lowering blood glucose, while 20 mg/kg BW to lowering MDA level. Conclusion : The multilevel doses β-carotene (1 mg/kg BW, 10 mg/kg BW and 20 mg/kg BW) on alternate days within 30 days orally supplementation can decrease blood glucose and MDA level. β-carotene 10 mg/kg BW is the most effecetive and efficient to decrease blood glucose and β-carotene 20 mg/kg BW to decrease MDA level.
Efek suplementasi β-carotene terhadap kolesterol total, trigliserida dan malondialdehid pada tikus sprague dawley yang diabet Ermawati, Devi; Rachmawati, Banundari; Widyastiti, Nyoman Suci
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 2, No 2 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (392.108 KB) | DOI: 10.14710/jgi.2.2.47-52

Abstract

Background : diabetes mellitus (DM) is associated with increased total cholesterol and triglyceride, also well characterized by increased malondialdehyde production. β-carotene has antioxidant activity, glycemic and lipid control. Objective : to analyze the effect of β-carotene on total cholesterol, triglyceride and MDA on diabetic Rattus norvegicus sprague dawley. Methods : thirty rats were randomly divided into 5 groups : 1 (STZ), 2 (STZ+β-carotene 1 mg/kg BW), 3 (STZ+β-carotene 10 mg/kg BW), 4 (STZ+β-carotene 20 mg/kg BW), 5 (normal). Streptozotocin induced intraperitoneal 40 mg/kg BW. β-carotene was given by nasogastric tube on alternate days within thirty days. Blood glucose level was measured by GOD-PAP, total cholesterol by CHOD-PAP, triglyceride by GPO and MDA by ELISA with TBARS methods. Hypothesis test used one way anova then followed by post hoc bonferroni to analyze the efficient dose effect. Results : there was a significant difference of total cholesterol (p=0.002) after β-carotene 10 mg/kg BW supplementation on alternate days within 30 days orally. β-carotene 10 mg/kg BW was the most efficient dose to lowering total cholesterol. There were significant differences of triglyceride (p=0.0001) and MDA (p=0.0001) after β-carotene 1, mg/kg BW, 10 mg/kg BW and 20 mg/kg BW supplementation on alternate days within 30 days orally. β-carotene 10 mg/kg BW was the most efficient dose to lowering triglyceride, while 20 mg/kg BW to lowering MDA. Conclusion : β-carotene 10 mg/kg BW is the most efficient dose to lowering total cholesterol and triglyceride. β-carotene 20 mg/kg BW is the most efficient dose to lowering MDA.
PENGARUH PEMBERIAN JAMUR KUPING HITAM (AURICULARIA POLYTRICHA) TERHADAP KADAR TRIGLISERID SERUM TIKUS WISTAR YANG DIINDUKSI MINYAK JELANTAH I Made Miarta Yasa; Henna Rya Abdurachmin; Nyoman Suci Widyastiti
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 6, No 2 (2017): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.027 KB) | DOI: 10.14710/dmj.v6i2.18582

Abstract

Latar belakang : Pada era modern seperti sekarang ini banyak sekali orang-orang yang lebih memilih untuk makan-makanan cepat saji. Namun biasanya minyak yang digunakan untuk menggoreng makanan tersebut adalah minyak jelantah. Padahal minyak jelantah itu sendiri memiliki lemak trans yang begitu tinggi, sehingga menyebabkan naiknya kadar kolesterol salah satunya trigliserid. Hal itu dapat menyebabkan meningkatnya kejadian suatu penyakit seperti aterosklerosis. Jamur kuping hitam diketahui memiliki kandungan vitamin, polisakarida, dan zat-zat lain yang dapat menurunkan kadar trigliseridaTujuan : Mengetahui efek pemberian jamur kuping hitam terhadap penurunan kadar trigliserid pada tikus wistar jantan yang diinduksi minyak jelantahMetode : Penelitian ini berjenis true eksperimental dengan post-test only with control group design menggunakan 24 tikus wistar sebagai objek percobaan. Kemudian dibagi menjadi 4 kelompok. Kelompok K1 diberi diet standar dan aquades 2ml/200 gramBB. Kelompok K2 diberi diet standar, aquades 2ml/200 gramBB dan minyak jelantah sebanyak 3ml/200 gramBB. Kelompok K3 diberi diet standar dan air rebusan jamur kuping hitam sebanyak 2ml/200 gramBB. Dan kelompok  K4 diberi diet standar, minyak jelantah 3ml/200 gramBB, dan air rebusan jamur kuping hitam 2ml/200 gramBB. Data dianalisis dengan uji Saphiro-Wilk, Levene test, oneway ANOVA, dan Post Hoc testHasil : Diperoleh hasil yang signifikan dilihat dari rerata kelompok dengan  kadar trigliserid dimulai dari terendah yaitu kelompok K3 (81,56 mg/dL),kemudian kelompok K1 (88,88 mg/dL),kemudian kelompok K4 (98,99 mg/dL),dan terakhir kemudian kelompok K2 (129,42 mg/dL)Simpulan : Pemberian air rebusan jamur kuping hitam dapat menurunkan kadar trigliserid
PENGARUH PEMBERIAN JAMUR KUPING HITAM (AURICULARIA POLYTRICHA) TERHADAP KADAR KOLESTEROL TOTAL SERUM TIKUS WISTAR YANG DIINDUKSI MINYAK JELANTAH Ratih Budinastiti; Henna Rya Abdurachmin; Nyoman Suci Widyastiti
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (355.077 KB) | DOI: 10.14710/dmj.v5i4.15821

Abstract

Latar Belakang: Pemberian minyak jelantah berpengaruh terhadap kenaikan kadar kolesterol total (TC). Hal ini meningkatkan resiko terjadinya aterosklerosis yang berdampak pada timbulnya penyakit kardiovaskuler. Jamur kuping hitam merupakan antioksidan alami yang mengandung polisakarida, flavonoid, niacin, dan vitamin C yang dapat memperbaiki profil lipid. Tujuan: Menganalisis pengaruh pemberian air rebusan jamur kuping hitam terhadap kadar TC serum tikus wistar yang diinduksi minyak jelantah. Metode: Penelitian true experimental dengan rancangan post test only control group design ini menggunakan tikus Wistar jantan usia 12 minggu (n=24) yang secara random dibagi menjadi 4 kelompok. K1 sebagai kontrol negatif, K2 diberi minyak jelantah, K3 diberi air rebusan jamur kuping, K4 diberi minyak jelantah dan air rebusan jamur kuping. Kadar TC serum kemudian diukur dengan metode CHOD-PAP setelah perlakuan selama 28 hari. Hasil: Rerata kadar TC K1 (80,2217±3,61 mg/dL), K2 (195,8483±5,47 mg/dL), K3 (75,5800±4,02 mg/dL), dan K4 (110,8683±5,82 mg/dL); p=0,000. Simpulan: Air rebusan jamur kuping menurunkan kadar kolesterol total serum pada tikus wistar yang diinduksi minyak jelantah.
ASSOCIATION BETWEEN 25-HYDROXYVITAMIN D LEVELS AND GROWTH PARAMETERS IN THALASSEMIA WITH REPEATED BLOOD TRANSFUSION Najma Khairani Harahap; Mulyono Mulyono; Yetty Movieta Nency; Nyoman Suci Widyastiti
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 6 (2020): DIPONEGORO MEDICAL JOURNAL (Jurnal Kedokteran Diponegoro)
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v9i6.29325

Abstract

Background. Blood transfusion is a therapeutic choice for thalassemia with anemia. Hemosiderosis is the side effects of blood transfusions which cause impaired liver function, leads to low vita­min D levels in plasma. The low level of vitamin D cause delay in physical growth. The aim is to determine the relation between 25-hydroxyvitamin D levels and growth parameters in thalassemia with repeated blood transfusion history. Method. In this analytical cross-sectional study, thalassemia patients with repeated blood transfusion and ages 0-18 years old were recruited. This research was held in Semarang, Purwodadi, and Rembang from May to September 2019. Thalassemia patients who met the criteria were measured the 25-hydroxyvitamin D level, physical activity and the growth parameters (weight, height, and body mass index). Results. Forty thalassemia patients aged 6-18 years old were recruited in this study. The percentage of boys are 47.5% and girls are 52.5%. Most of subject had high ferritin serum (87.5%) and low vitamin D level (87.5%). Growth parameters from the patients were 52.5% weight-for-age <5 percentile, 45% height-for-age <5 percentile and 25% BMI-for-age underweight. There isn’t significant result in 25-hydroxyvitamin D with growth parameters, and a significant result between physical activity and height-for-age (p=0.027), but not with weight-for-age and BMI-for-age. Conclusion. The 25-hydroxyvitamin D do not associate with growth parameters significantly in thalassemia with repeated blood transfusion but physical activity has significant association with height-for-age.
UJI SENSITIVITAS DAN SPESIFISITAS MENTZER INDEX, RED DISTRIBUTION WIDTH INDEX DAN GREEN AND KING INDEX TERHADAP DIAGNOSIS TALASEMIA BETA MINOR DAN ANEMIA DEFISIENSI BESI Ruth Hanna Kristina; Nyoman Suci Widyastiti; Edward Kurnia Setiawan
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 7, No 2 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.775 KB) | DOI: 10.14710/dmj.v7i2.20740

Abstract

Latar belakang: Anemia mikrositik hipokromik sering disebabkan oleh anemia defisiensi besi dan talasemia beta minor. Pemeriksaan baku emas talasemia beta adalah pemeriksaan genetik, sedangkan anemia defisiensi besi adalah pemeriksaan cadangan besi sumsum tulang. Kedua pemeriksaan tersebut memakan biaya yang mahal. Perlu adanya teknik skrining berupa indeks perhitungan yang adekuat dengan biaya yang terjangkau.Tujuan: Mengetahui dan membandingkan nilai sensitivitas dan spesifisitas Mentzer Index, Red Distribution Width Index dan Green and King Index.Metode: Penelitian ini merupakan penelitian uji diagnostik. Terdapat 98 data anemia mikrositik hipokromik yang terdiri dari masing-masing 49 anemia defisiensi besi dan talasemia beta minor. Dilakukan perhitungan Mentzer index, Red Distribution Width Index dan Green and King Index yang dibandingkan dengan parameter diagnosis untuk mengetahui nilai sensitivitas dan spesifisitas. Parameter diagnosis emas yaitu ferritin serum atau TIBC atau besi serum untuk diagnosis anemia defisiensi besi dan hemoglobin A2 untuk diagnosis talasemia beta minor.Hasil: Mentzer index memiliki nilai sensitivitas dan spesifisitas untuk mendeteksi anemia defisiensi besi sebesar 93,88% dan 87,76%, dan talasemia beta minor sebesar 87,76% dan 93,88%. RDWI index memiliki nilai sensitivitas dan spseifisitas untuk medeteksi anemia defisiensi besi sebesar 89,80% dan 83,67%, dan untuk talasemia beta minor sebesar 83,67% dan 89,80%. Green and King index memiliki nilai sensitivitas dan spesifisitas anemia defisiensi besi sebesar 91,84% dan 77,55%, dan untuk talasemia beta minor sebesar 77,55% dan 91,84%.Kesimpulan: Mentzer index memiliki nilai sensitivitas dan spesifisitas tertinggi sehingga dapat digunakan sebagai teknik skrining untuk mendiagnosis talasemia beta minor dan anemia defisiensi besi.
Co-Authors Abd. Rasyid Syamsuri Adieba Warda Hayya Afriana, Rizky Dyas Agus Fitrianto Ainun Najib Amelia, Sesa Anies Anies Ardhea Jaludamascena Ariosta Ariosta Arulita Ika Fibriana Astika Widy Utomo, Astika Widy Azizah, Arfianty Nur Banundari Rachmawati Budhi Setianto Dea Amanda Caressa Devi Ermawati Diana Nur Afifah, Diana Nur Djuara P Lubis Dwi Retnoningrum Edi Dharmana Edi Dharmana Edward Kurnia Setiawan Edward Kurnia Setiawan Limijadi Edward Kurnia Setiawan Limijadi, Edward Kurnia Setiawan Ekowati, Liana Elida Soviana Elsa Naviati Erna Mirani Etika Ratna Noer Fathur Nur Kholis Galang Bela Nusa Hadian Hadian Hardhono Susanto Hardhono Susanto Henna Rya Abdurachmin Hertanto Wahyu Subagio I Made Miarta Yasa Ima Arum Lestarini Imam Budiwiyono Indranila Kustarini Samsuria K. Heri Nugroho HS, K. Heri Kurniawan, Muhammad Farhan Kusmiyati DK Kusmiyati Tjahjono Mabruratussania Maherdika Mahalul Azam Maria Mexitalia Martha Irene Kartasurya Meira Erawati Meita Hendrianingtyas Moedrik Tamam Moedrik Tamam Muji Rahayu Mulya Agustina Mulyono Mulyono Muniroh, Muflihatul Nahwa Arkhaesi Najma Khairani Harahap Naufal, Haidar Satya Novianti, Anugrah Nugroho, Trilaksana Partiwi, Rina Purwanto Adipireno Purwanto AP R. Lindeman Ratih Budinastiti Retnoningrum, Dwi Rina Pratiwi Roziana Roziana, Roziana Rr. Sri Ratna Rahayu Ruth Hanna Kristina Safitri, Titis Yoga Saputra, Taufik Setianingrum, Elisabeth Levina Sari Setiawan L, I Edward Kurnia Silitonga, Marisi Elizabeth R. Suhartono Suhartono, Suhartono Susanti Lestari Thijs Eijsvogels Tri Indah Winarni Udin Bahrudin Umi S Intansari Widodo, Sabar Widyastuti, Trioni Yanuarita Tursinawati Yanuarius Alvin Pratama Budianto Yetty Movieta Nancy Yetty Movieta Nency Yetty Movieta Nency Yetty Movieta Nency, Yetty Movieta Yuliana Yuliana Zetta, Adelia Paradya