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PROFILAKSIS PRA-PAJANAN (PPrP) HIV/AIDS PADA LELAKI SEKS LELAKI Teddy Tjahyanto; Natasha Cita Paradhita Kusuma; Agnes Marcella; Gladys Ariella; Alicia Sarijuwita
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 6 No. 1 (2022): April 2022
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v6i1.2816

Abstract

Introduction: HIV is an infection that attacks the immune system which is characterized by a decrease in CD4+ cells with MSM as the 2nd largest contributor globally. PPrP serves as an additional option in the prevention of HIV-negative MSM from becoming infected with HIV. Objective: This study was conducted to review more deeply the role of pre-exposure prophylaxis in reducing the risk of contracting HIV in male sex groups with HIV negative men and to review the effectiveness and implementation of HIV/AIDS pre-exposure prophylaxis in male sex men so that it is expected to be a consideration in efforts to combat HIV/AIDS. Methods: Literature search was conducted from journal articles published online in the period 2012-2021. The databases used are ScienceDirect, Pubmed, Google Scholar, and Cochrane. Results: The study showed that the factors that significantly affected the high prevalence of HIV cases among MSM were anal sex and based on the findings the use of PrEP showed a significant effectiveness for the MSM group with pre-exposure prophylaxis as a preventive measure in dealing with HIV positive cases. Conclusion: PrEP has been shown to significantly reduce the risk of contracting HIV in HIV-negative MSM groups and has the potential to be an additional prevention option so that it can be applied in efforts to prevent HIV infection and reduce the spread of HIV in MSM.
Kegiatan Pengabdian Masyarakat dalam Rangka Edukasi Masyarakat Terhadap Hipertensi serta Deteksi Dini Penyakit Gagal Ginjal Sebagai Komplikasi dari Hipertensi Donatila Mano S; Pasuarja Jeranding Ezra; Agnes Marcella; Yohanes Firmansyah
JURNAL PENGABDIAN MASYARAKAT INDONESIA Vol. 2 No. 2 (2023): Juni : Jurnal Pengabdian Masyarakat Indonesia (JPMI)
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpmi.v2i2.1776

Abstract

Hypertension and kidney failure are two types of diseases related to kidney health. Hypertension or high blood pressure can cause damage to the kidneys, while kidney failure is a condition in which the kidneys cannot function properly to build up metabolic waste and fluids from the body. Hypertension can cause damage to the small blood vessels in the kidneys, so that the kidneys cannot excrete waste properly. As a result, harmful substances can accumulate in the body and cause organ damage. If hypertension cannot be controlled properly, it can cause kidney damage and eventually lead to kidney failure. Failure is a kidney condition in which the kidneys cannot function properly to remove metabolic wastes and fluids from the body. Kidney failure can occur for a variety of reasons, including untreated hypertension, diabetes, congenital kidney disease, and use of certain medications. If left untreated, kidney failure can lead to accumulation of waste in the body and serious complications such as anemia, osteoporosis, heart disease and even death. Treatment of hypertension and kidney failure usually involves medication and lifestyle changes. Treatment includes the use of drugs prescribed by a doctor and the management of complications that may occur. Lifestyle changes include managing a healthy diet, reducing salt and fat consumption, exercising regularly, avoiding smoking, and managing stress. Early detection is very important in the management of hypertension and kidney failure. Regular blood pressure checks, urine tests to detect protein in the urine, and blood tests to detect levels of creatinine, blood glucose, and cholesterol in the blood can help detect risks and early symptoms of kidney disease.
Hubungan Kadar HBA1C dan Insulin Puasa Terhadap Infeksi Saluran Kemih Pada Kelompok Lanjut Usia di Panti Santa Anna Donatila Mano S; Zita Atzmardina; Alexander Halim Santoso; Fernando Nathaniel; Joshua Kurniawan; Dean Ascha Wijaya; Eric Raditya Kaminto; Andini Ghina Syarifah; Pasuarja Jeranding Ezra; Agnes Marcella; Rifi Nathaznya Syachputri
Malahayati Nursing Journal Vol 6, No 7 (2024): Volume 6 Nomor 7 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i7.13510

Abstract

ABSTRACT Urinary tract infection (UTI) poses a serious concern in the elderly population, with approximately 25% of total infection cases in the geriatric group being UTIs. Diabetes mellitus stands as a leading cause of global morbidity and is associated with severe complications, including an increased risk of infections impacting the quality of life. Patients with diabetes face a twofold higher risk of mortality due to infections. Advanced age is also a risk factor for UTIs, influenced by factors such as uncontrolled diabetes. Measuring parameters such as fasting insulin and HbA1c levels is crucial for understanding correlation between diabetes and UTIs. HbA1c can reflect long-term glycemic control in diabetic patients. This cross-sectional study aims to investigate relationship between HbA1c and fasting insulin levels concerning the occurrence of UTIs in the elderly population, conducted at the Santa Anna Nursing Home in 2023. The study included 33 respondents with an average age of 72.88 years, predominantly comprising 24 female respondents (72.7%). The mean fasting insulin level was 12.46 mIU/mL, and HbA1c level was 5.97%. UTIs were diagnosed in 11 respondents (33.3%). The correlation analysis between these variables indicated no significant difference in the mean HbA1c levels between groups with or without UTIs (p = 0.955). However, a significant difference was observed in the mean fasting insulin levels between the two groups (p 0.001). This finding is noteworthy as fasting insulin levels have a direct correlation with circulating blood glucose levels and formation of red blood cells, potentially influencing HbA1c levels. Further clarification is needed on how these three variables interact. Keywords: Elderly, Fasting Insulin, HbA1c, Urinary Tract Infection  ABSTRAK Infeksi saluran kemih (ISK) adalah masalah serius pada populasi lanjut usia, sekitar 25% dari total kasus infeksi pada kelompok geriatri adalah ISK. Diabetes melitus adalah penyebab utama morbiditas global dan berhubungan dengan komplikasi serius, termasuk risiko infeksi yang berdampak pada kualitas hidup. Pasien diabetes memiliki risiko dua kali lipat lebih tinggi untuk kematian akibat infeksi. Peningkatan usia juga merupakan faktor risiko untuk ISK, yang dipengaruhi oleh faktor-faktor seperti diabetes yang tidak terkontrol. Pengukuran parameter seperti insulin puasa dan HbA1c adalah kunci dalam memahami korelasi antara diabetes dan ISK. HbA1c dapat mencerminkan kontrol glikemik jangka panjang pada pasien diabetes. Penelitian potong lintang ini bertujuan untuk mengetahui hubungan antara kadar HbA1c dan insulin puasa terhadap kejadian ISK pada kelompok lanjut usia yang dilakukan di Panti Lansia Santa Anna pada tahun 2023. Penelitian mengikutsertakan 33 responden dengan rata-rata usia 72,88 tahun dan didominasi oleh jenis kelamin perempuan  sebanyak 24 responden (72,7%). Rerata kadar insulin puasa sebesar 12,46 mIU/mL dan kadar HbA1c sebanyak 5,97%. Sebanyak 11 responden (33,3%) terdiagnosis ISK. Hasil korelasi antara kedua variabel tersebut menunjukkan bahwa tidak ada perbedaan signifikan dalam rerata kadar HbA1c antara kelompok dengan atau tanpa ISK (p = 0,955). Meskipun demikian, terdapat perbedaan signifikan dalam rerata kadar insulin puasa antara kedua kelompok (p 0,001). Hal ini menjadi sebuah pertimbangan karena kadar insulin puasa memiliki korelasi langsung dengan jumlah gula yang beredar bebas dalam darah dan pembentukan sel darah merah yang dapat meningkatkan tingkat HbA1c. Diperlukan penjelasan lebih lanjut tentang bagaimana ketiga variabel ini berinteraksi. Kata Kunci: HbA1c, Infeksi Saluran Kemih, Insulin Puasa, Lanjut Usia