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All Journal JOPS (Journal Of Pharmacy and Science) Jurnal Mandala Pharmacon Indonesia Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Kesehatan Tambusai Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana (JUFDIKES) Jurnal Pengabdian Masyarakat Nusantara Jurnal Sains dan Kesehatan International Journal of Health Science
Rahmat Ismail
Universitas Muhammadiyah Manado
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PENGARUH PEMBERIAN REBUSAN DAUN SELEDRI TERHADAP TEKANAN DARAH PADA PASIEN HIPERTENSI DI KELURAHAN MAHAWU KOTA MANADO Rahmat Ismail; Fitriyana Junaidi
JURNAL FISIOTERAPI DAN ILMU KESEHATAN SISTHANA Vol. 4 No. 1 (2022): Januari : Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jufdikes.v4i1.700

Abstract

Hypertension is an abnormal increase in blood pressure in the arteries continuously over a period of time. A person is said to be hypertensive if the systolic blood pressure is equal to or above 140 mmHg and/or the diastolic blood pressure is equal to or above 90 mmHg. The high prevalence of hypertension is one of the problems that affect public health status. The purpose of this study was to determine the effect of giving celery leaf decoction on blood pressure in hypertension patients in Mahawu, Manado This research design is a pre-experimental research design (one-group pre-post test design). The population in this study amounted to 53 patients with the sample used was 17 respondents. The sampling technique used is Accidental Sampling. Data collection using blood pressure observation sheet. The results of the study found that giving boiled celery leaves before giving boiled celery leaves were 12 respondents (70.6%). And after giving boiled celery leaves, 13 respondents (76.5%). The result of p value 0.000 (<0.05) so Ha is accepted. There is an effect of giving boiled celery leaves on blood pressure in hypertensive patients in Mahawu, Manado. The conclusion in this study is that there is an effect of giving celery leaf decoction on blood pressure in hypertension patients in Mahawu, Manado. Suggestions to respondents who often experience hypertension can do their own treatment when high blood pressure by boiling celery leaves.
Antihyperglycemic Effectiveness of Ethanolic Extract of Takokak Fruit (Solanum Torvum Swartz) on Male White Rats (Rattus Norvegicus) Induced by Glucose Rahmat Ismail; Ahlan Sangkal
International Journal Of Health Science Vol. 5 No. 2 (2025): International Journal of Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v5i2.5679

Abstract

Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels resulting from impaired insulin secretion, insulin resistance, or a combination of both. This condition requires long-term treatment and has the potential to lead to serious complications if not properly managed. The search for alternative herbal-based treatments has become a major focus of various pharmacological studies. One such plant with potential is the takokak fruit (Solanum torvum Swartz), which has traditionally been used to treat various health conditions such as hypertension, microbial infections, and reproductive system disorders, as well as possessing antipyretic and antidiabetic properties. This study aimed to evaluate the antihyperglycemic efficacy of the takokak fruit ethanol extract in glucose-induced male white rats (Rattus norvegicus). The extract was obtained through a maceration method using 96% ethanol as a solvent. Five test groups were prepared, each consisting of three rats: a negative control group (Na-CMC), a positive control group (metformin), and three treatment groups with takokak extract concentrations of 5%, 10%, and 20%. Glucose induction was administered orally, and after 30 minutes, the extract was administered to the treatment group, and blood glucose levels were measured for two hours. The results showed that the takokak fruit extract was able to reduce blood sugar levels by 27% in the 5% group, 25% in the 10% group, and 33% in the 20% group, respectively. However, the ANOVA statistical test yielded a significance value of 0.48, indicating that the difference in blood glucose reduction between the groups was not statistically significant. Although not yet significant, these results indicate that the ethanol extract of takokak fruit has potential as an antihyperglycemic agent, which requires further research on a larger scale and duration to obtain more conclusive results.
Co-Authors Abulkhair Abdullah Adelin Liputo Ahlan Sangkal Ayu Pratiwi Dora Susetyaningdyah Fitriyana Junaidi Hamidah Sri Supriati Moh. Perdana M. Mo’o Muhammad Asrhah Hidayah Mutmainnah Mutmainnah Nasyruddin Abdullah Nurfatima S. Marasabessy Nurul Hastuti Raun Randi R. Toboleu Rifa’atul Mahmudah Rizal Windi Astuti