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All Journal e-Journal Pustaka Kesehatan STOMATOGNATIC- Jurnal Kedokteran Gigi MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal UNEJ e-Proceeding Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Journal of Dentomaxillofacial Science Masyarakat Telematika Dan Informasi : Jurnal Penelitian Teknologi Informasi dan Komunikasi Padjadjaran Journal of Dental Researchers and Students Prosiding Seminar Nasional Teknik Mesin INSERT: Information System and Emerging Technology Journal Indonesian Journal of Visual Culture, Design, and Cinema (IJVCDC) Odonto dental journal Aksa : Jurnal Desain Komunikasi Visual Sungging
Budi Yuwono
Fakultas Kedokteran Gigi Univeritas Jember Jl. Kalimantan 37 Jember
Aerospace Engineering Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Dentistry Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Other

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Journal : e-Journal Pustaka Kesehatan

 1 
Kadar Serum Glutamic Oxaloacetic Transaminase (SGOT) pada Tikus Wistar (Rattus norvegicus) Jantan yang Dipapar Stresor Rasa Sakit Electrical Foot Shock selama 28 Hari (The Level of Serum Glutamic Oxaloacetic Transaminase (SGOT) in Male Wistar Rat (Ratt Nur Lely Yaumil Qodriyati; Erna Sulistyani; Budi Yuwono
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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  Stress is a natural reaction that allows the human compelled to face the difficulties. Stimuli that causes stress can be physical and psychological. Physical stressors can occur continuously or sustained, which causes pathological processes in the body. This pathological process may be occur in liver and heart. One of parameter to assess characteristics of tissue can use Serum Glutamic Oxaloacetic transaminase (SGOT). The aim of this study was to prove differences level of SGOT in male Wistar rats (Rattus norvegicus) that exposed and control group were not exposed by pain stressor electrical foot shock for 28 days. Blood sampling was carried out on day 28 in intracardiac then tested the levels of SGOT. Statistical analysis showed that there was no significant change (p≤0,05) between control and treatment group. Liver damage from stressors may be not cause necrosis of liver cells. SGOT was not a single biomarker that was specific and sensitive for the diagnosis of liver disease because SGOT was also found in the heart.   Keywords: electrical foot shock, SGOT, stress
Pengaruh Pemberian Ekstrak Propolis Terhadap Kadar Kolesterol Darah Tikus Wistar Jantan Setelah Dipapar Sidestream Cigarette Smoke (Effect of Propolis Extract on Blood Cholesterol Level in Male Wistar Rats After Being Exposed to Sidestream Cigarette Smoke Chusna Sekar Wardani; Roedy Budirahardjo; Budi Yuwono
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Smoking is one of environment factors which caused a bad effect for health. TheSidestream Cigarette Smoke (SCS) contained in smoke produce free radicals highly andincrease total cholesterol levels. Elevated levels of total cholesterol can be treated withmedicine of statins, but its use in the long term cause side effects. Therefore, at thistime medicine has been developed from natural a substance which is expected haveless side effects, one of which is propolis. This research aims to determine whether thereis a decrease in total cholesterol levels in male Wistar rats (Rattus norvegicus) whichwas given extracts of propolis and exposed SCS. The research is experimentallaboratory with post test control group design. This research uses 12 rats which consistof 2 groups (1 control and 2 groups of treatment). The first treatment group is exposedby SCS. The second one is exposed by SCS and given the extract of propolis 2 times aday for 8 days. The total blood cholesterol level is measured by usingspectrophotometer with enzymatic colorimetric methods. The results of data analysisusing One Way Anova test shows there is a significant difference in total bloodcholesterol level means of male Wistar rats (p <0.05). While the Tukey HSD test showsthere is a significant difference in total cholesterol level means between groups, exceptbetween the control group and the second treatment group. Conclusion of thisresearch is that the propolis extract can lower total cholesterol levels of male Wistar ratswhich given exposure of Sidestream Cigarette Smoke.Keywords: blood cholesterol levels, propolis extract, sidestream cigarette smoke
Efektivitas Seduhan Daun Yakon (Smallanthus sonchifolius) terhadap Kadar Low Density Lipoprotein (LDL) dan High Density Lipoprotein (HDL) pada Tikus Diabetik yang Diinduksi Streptozotocin (The Efectivity of  Yacon Leaves (Smallanthus sonchifolius) Infusion to Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL) Level in Diabetic Rats Induced by Streptozotocin) Vitta Permata Sarie; Roedy Budirahardjo; Budi Yuwono
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Diabetes mellitus (DM) is a metabolic disorder characterized by elevated level of blood glucose abnormalities associated with the metabolism of carbohydrates,lipids and proteins. Lipids metabolism disorder can increase LDL and lower HDL level. One of plants in Indonesia, that has potential as antihyperglycemic and hypolipidemic agent is yakon (Smallanthus sonchifolius) containing chlorogenic acid (CGA). This study aimed to determine the effect of yacon leaves infusion to LDL and HDL level in diabetic rats induced by streptozotocin (STZ). This study was an experimental research laboratories with the post test only control group design. Rats checked the blood glucose early then induced by STZ with dose 65 mg / kg BW. At 3 days post injection, they were checked the blood glucose. Then the rats were divided into 2 groups the control and treatment group. The treatment group was given yacon leaves infusion ( 3.6 ml/200 g BB rats ) for 14 days. Then they were checked LDL and HDL level by using electrospectrofotometer. Statistical analysis showed that there were significant differences in LDL level and no significant difference in HDL level. It could be concluded that the yacon leaves infusion could lower LDL level in diabetic rats induced by STZ, while HDL level had not change. Keywords: Diabetic, HDL, LDL, yacon
Pengaruh Daun Katuk (Sauropus androgynus (L.) Merr.) terhadap Waktu Perdarahan (Bleeding Time) pada Tikus Wistar Jantan sebagai Alternatif Obat Antitrombotik (The Effect of Star Gosseberry (Sauropus androgynus (L.) Merr.) to bleeding time of Male Wistar Selvia Magdalena; Budi Yuwono; Agustin Wulan Suci Dharmayanti
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Cardiovascular disease can be treated with synthetic or traditional antithrombotic drugs (herbal). Synthetic antithrombotic drugs have a lot of side effects, so as an alternative antithrombotic is used traditional drugs, star gosseberry. Star gosseberry have many active compounds which are suspected to inhibit platelet aggregation. Objective: to know the effect of star gosseberry on bleeding time of male Wistar rats as an alternative antithrombotic drugs. Methods of research: this study was experimental laboratory research with post-test only control group design. The research samples were 24 male wistar rats and divided into 4 groups: negative control (distilled water), positive control (aspirin 5,85 mg dose), treatment 1 (star gosseberry 4,5 mg/g dose), and treatment 2 (star gosseberry 2.25 mg/g dose). The treatment was given for 8 days then the tail of samples were cut by 0.5 cm from the tip of the tail. Every 30 seconds the blood that dripped out was absorbed on absorbent papers until the bleeding stops. Bleeding time was measured from initial point of bleeding until the cessation of the bleeding point. Result: star gosseberry dose 4,5 mg/g had the same effect as aspirin that was prolonged bleeding time. Conclusion: star gosseberry could be prolonged bleeding time so it can be used as an alternative antithrombotic drugs. Keywords: Katuk leaf, bleeding time, antithrombotic, platelet
Co-Authors Agustin Wulan Suci Dharmayanti Alfiansyah, Muhammad Abi Alifia Wandansari Ariek Sulistyowati, Ariek Arinanda, Aditya Atik Kurniawati Aviandi, Ivano Azevie, Umarta Rizky Chusna Sekar Wardani Daniel, Faisal Bramantyo Desi Sandra Sari Dessy Rachmawati Dewi Muflikhah Erna Sulistyani Febryane, Zarrina Eltri Ghani, Oktaviani Ghina Lady Salsabila I Nyoman Sujana Kumala, Efa Ayu Ratnaning Leonardo, Vande Maisyatul Ihsaniyah Mei Syafriadi Muhammad Nasri Muhammad Nurul Amin Mulia Widya Winiswara Muttaqin, Muhammad Hasan Nidha Tuhu Respati Karno Nugraha, Rinaldi Pratama Nur Indrawati, Nur Nur Lely Yaumil Qodriyati Rekimsa, Anugrah Yusuf Rina Sutjiati Rizki, Alifka Dimas Robbiya, Maiya Arsya Roedy Budirahardjo Rohim, Fatur Ruslam, Reza Zulfikar Safira Niza Ulfita Saputra, I Nyoman Sujana Saputra, Tedi Selvia Magdalena Siti Aisyah Swasthi Prasetyarini Triputra, Rein Nusa Vijaya, Annas Vitta Permata Sarie Winny Adriatmoko Yani C. Rahayu Yani Corvianindya Rahayu Zainul Cholid