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All Journal Jurnal Kesehatan Andalas Jurnal Sains dan Teknologi Farmasi JFIOnline
Nasrul Zubir
Bagian Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Andalas, Jl. Perintis Kemerdekaan, PO Box 49, Padang Sumatera Barat
Computer Science & IT Education Health Professions Medicine & Pharmacology

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Pengaruh Pemberian Kromium (III) Klorida Terhadap Kadar SGPT Darah Mencit Putih Dharma, Surya; BP, Zesfin; H, Irsan Ryanto; Zubir, Nasrul
Jurnal Sains dan Teknologi Farmasi Vol 15 No 1 (2010)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

The researh has been done on the influence of giving chromium (III) chloride on white mice blood SGPT.  The researh was divided into 5 groups, that is control,  doses ( 5,2; 6,37 and 7,8 ug/20 BW) with vitamin C and the dose of 7,8 ug/20 g BW without vitamin C. The observation was done for 42 days, that is day 7 th, 21 st and 42 nd with parameter SGPT concentration level. Results indicated that all doses showed the increase in SGPT concentration significantly (p<0,05).
PENGARUH PEMBERIAN KROMIUM (III) KLORIDA TERHADAP SPERMATOZOA MENCIT PUTIH Dharma, Surya; BP, Zesfin; Zubir, Nasrul; H, Irsan Ryanto.
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 5, No 2 (2010)
Publisher : Indonesian Research Gateway

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Abstract

A study on the effect of chromium chloride on motility, viability and totality of spermatozoa the male with mice. The drugs was given  orally with doses 5,2 ; 6,37 and 7,8 µg/20 g BB with vitamin C and doses  7,8 µg/20 g BB without vitamin C. The treatment and giving of drugs were carried out  for 40 days and removal of spermatozoa was done at at the day 7, 21 and 42 were taken vas deferens and epididymis, until result the suspension of spermatozoa. The result indicated that the giving chromium (III) chloride with vitamin C give effect to decrease motility, viability and totality of spermatozoa the male wihite mice at p<0,05 ABSTRAK Telah dilakukan penelitian tentang pengaruh pemberian senyawa kromium (III) klorida terhadap motilitas, viabilitas dan jumlah spermatozoa mencit putih jantan. Hewan dibagi atas 5 kelompok  dengan 3 variasi dosis ( 5,2; 6,37 dan 7,8 µg/20 BB) dengan lama perlakuan selama 42 hari yang diamati pada hari ke 7, 21 dan 42.. Hasil menunjukan bahwa setelah pemberian senyawa kromium (III) klorida pada 3 variasi dosis terjadi penurunan motilitas, viabilitas dan jumlah spermatozoa mencit putih jantan secara bermakna
PENGARUH PEMBERIAN KROMIUM (III) KLORIDA TERHADAP SPERMATOZOA MENCIT PUTIH Dharma, Surya; BP, Zesfin; Zubir, Nasrul; H, Irsan Ryanto.
Jurnal Farmasi Indonesia Vol 5, No 2 (2010)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v5i2.43

Abstract

A study on the effect of chromium chloride on motility, viability and totality of spermatozoa the male with mice. The drugs was given  orally with doses 5,2 ; 6,37 and 7,8 µg/20 g BB with vitamin C and doses  7,8 µg/20 g BB without vitamin C. The treatment and giving of drugs were carried out  for 40 days and removal of spermatozoa was done at at the day 7, 21 and 42 were taken vas deferens and epididymis, until result the suspension of spermatozoa. The result indicated that the giving chromium (III) chloride with vitamin C give effect to decrease motility, viability and totality of spermatozoa the male wihite mice at p<0,05 ABSTRAK Telah dilakukan penelitian tentang pengaruh pemberian senyawa kromium (III) klorida terhadap motilitas, viabilitas dan jumlah spermatozoa mencit putih jantan. Hewan dibagi atas 5 kelompok  dengan 3 variasi dosis ( 5,2; 6,37 dan 7,8 µg/20 BB) dengan lama perlakuan selama 42 hari yang diamati pada hari ke 7, 21 dan 42.. Hasil menunjukan bahwa setelah pemberian senyawa kromium (III) klorida pada 3 variasi dosis terjadi penurunan motilitas, viabilitas dan jumlah spermatozoa mencit putih jantan secara bermakna
Risiko Perdarahan Saluran Cerna pada Pasien COVID-19 berdasarkan Jenis Obat Antivirus di Rumah Sakit Umum Pusat Dr. M. Djamil Padang Arnelis, Arnelis; Miro, Saptino; Zubir, Nasrul; Yoga, Vesri; Kurniawan, Andry; Kam, Alexander; Rahimi, Abdul Alim; Ranazeri, Jersivindo; Fahrurozi, R. Ifan Arief
Jurnal Kesehatan Andalas Vol. 11 No. 2 (2022): Online July 2022
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v11i2.2042

Abstract

Coronavirus disease 2019 (COVID-19) has become a global pandemic to date. Some studies reported gastrointestinal tract (GIT) bleeding occurs in several patients hospitalized with COVID-19. Medications known to be associated with an increased risk of GIT bleeding were not associated with GIT bleeding in COVID-19 patients. Objectives: To examined the risk of gastrointestinal tract (GIT) bleeding in COVID-19 patients based on antiviral drugs at Dr. M. Djamil General Hospital Padang. Methods: A nested cohort study was conducted in Dr. M. Djamil General Hospital Padang from May until October 2021. All COVID-19 patients who received antiviral drugs with GIT bleeding with onset days 0 - 7 were included. COVID-19 was confirmed by RT-PCR swab. Data entry and analysis were conducted by computerized. Results: 30 patients were involved in this study. 43,3% COVID-19 Moderate stage and 56,7% Severe stage. 63,3% were treated with remdesivir and 36,7% were treated with favipiravir. Onset on GIT tract bleeding at day 4 (23,3%), day 5 (26.7%), day 6 (30%), and day 7 (20%). The Chi-square test to determine the factors associated with GIT bleeding in COVID-19 patients including COVID-19 severity, type of antiviral drugs, anticoagulant, and corticosteroid revealed that none of all potential factors above related to GI bleeding. Conclusion: The type of antiviral drugs was not related to GIT bleeding in COVID-19 patients.Keywords: antiviral drugs,  COVID-19, gastrointestinal tract bleeding
Co-Authors Adnil Edwin Nurdin Andry Kurniawan Arina Widya Murni Arnelis Arnelis Dona Elfina Eryati Darwin Fahrurozi, R. Ifan Arief H, Irsan Ryanto. H, Irsan Ryanto. Irsan Ryanto H Julius R. Samban Kam, Alexander Rahimi, Abdul Alim Ranazeri, Jersivindo Saptino Miro, Saptino Surya Dharma Yoga, Vesri Zesfin BP