Hanggara Arifian
Laboratorium Penelitian dan Pengembangan Kefarmasian "Farmaka Tropis", Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

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Sintesis 2’-Hidroksi-5’-Kloro-3,5-Dimetoksi-4-Hidroksikalkon Amanuddin Amanuddin; Hanggara Arifian; Agung Rahmadani; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 11 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.825 KB) | DOI: 10.25026/mpc.v11i1.393

Abstract

Chalcone are compounds that have 2 aromatic rings connected by 3 carbon atoms which are an ?, ? unsaturated carbonyl system that have various biological activities. 2'-hydroxy-5'-chloro-3,5-dimethoxy-4-hydroxicalcone was synthesized from 2'-hydroxy-5'-chloro acetophenone and syringaldehyde using a NaOH catalyst. This compound was purified using Column Chromatography by isocratic method using n-hexane:ethyl acetate (15:1) as eluent. This compound has a Rf 0.75 and 2.7% of yield.
Formulasi dan Evaluasi Nutrasetikal Gummy Candy dari Perasan Daun Kelakai (Stenochlaena Palustris (Burm.F.) Bedd): Formulation and Evaluation Nutraceutical Gummy Candy from Kelakai Leaf Juice (Stenochlaena Palustris (Burm.F.) Bedd) Winiaksa Tri Asdini; Hanggara Arifian; Nur Mita; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (256.967 KB) | DOI: 10.25026/mpc.v14i1.593

Abstract

Kelakai leaf (Stenochlaena palustris (Burm.F.) Bedd) is a typical plant of East Kalimantan with high iron content which can overcome anemia. The juice of anchovies was formulated into a nutraceutical gummy candy preparation using the Simplex Lattice Design (SLD) method. The results showed that the juice of anise leaves could be used as a gummy candy preparation with an evaluation results that meet the standard with a juice concentration of 9%, pH 5.4, chewy texture, elastic, strawberry essence aroma, sour taste, and brownish yellow color, 11.52% water content, and 2.30% ash content.