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All Journal Gema Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Indonesian Journal of Jamu
Fadilah Qonitah
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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SKRINNING FITOKIMIA EKSTRAK ETANOL DAUN JERUK PURUT (Citrus hystrix) DARI KABUPATEN KLATEN Fadilah Qonitah; Reni Ariastuti; Ahwan; Pratiwi Maharani, Nurul Astia Wuri
GEMA Vol 34 No 01 (2022): GEMA
Publisher : LP3M

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kaffir lime leaves are used for traditional medicine and cosmetic ingredients. Phytochemical screening aims to provide information related to the class of compounds contained in the ethanol extract of kaffir lime leaves. The extraction process uses the maceration method with ethanol 96%. The components contained in the extract were analyzed by their compounds by colour test (qualitative) with several reagents for flavonoids, saponins, tannins, terpenoids, steroids, alkaloids, and essential oils. The results of the phytochemical screening test showed that the ethanol extract of kaffir lime leaves contained a class of flavonoid compounds, saponins, tannins, triterpenoids, alkaloids and essential oils
Aktivitas Antibakteri Ekstrak Air, Etanol, Kloroform Teh Hijau (Camelia Sinensis L.) Terhadap Pertumbuhan Stophylococcus Epidermis Salwa Pratiwi; Ahwan; Fadilah Qonitah
An-Najat Vol. 2 No. 4 (2024): NOVEMBER - An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i4.1691

Abstract

Acne is a skin condition that often occurs on the face, neck, chest, and back. The oil glands in the skin are very active, causing the skin pores to become clogged with fat deposits. One of the factors causing acne is Staphylococcus epidermis bacterial infection, and skin conditions. Alternative treatments used are plants that have benefits as antibacterials. This study was experimental in nature, the aim of which was to determine the differences in the antibacterial activity test of Water Extract (EA), Ethanol Extract (EE), and Chloroform Extract (EK) of green tea leaves (Camellia Sinensis.L) against the growth of Staphylococcus epidermis bacteria. The disc diffusion method was used in testing antibacterial activity. The results showed that each positive extract had antibacterial activity against Staphylococcus epidermis bacteria with different levels of inhibition. The strong inhibition category is owned by EE 40% (12.41 ± 0.20) mm, EE 60% (14.4 ± 0.23) mm, EK 40% (11.5 ± 0.31) mm, and EK 60% (13.3 ± 0.1) mm. The moderate inhibition category is owned by EA 10%, (6.38 ± 0.15), EA 40% (8.53 ± 0.28), EA 60% (9.36 ± 0.21), EE 10% (9.76 ± 0.18) mm, and EK 10% (7.38 ± 0.20) mm. Meanwhile, the positive control of clindamycin 1.5% had a very strong inhibitory power with an average of (30.83 ± 0.10) mm, and the negative control of DMSO 1% had a weak inhibitory power of (0.00 ± 0.00). Based on the results of the study, it can be concluded that water, ethanol and chloroform extracts of green tea leaves have been proven to have antibacterial activity against Staphylococcus epidermis bacteria which are significantly different (p value 0.000 <0.05).
Penentuan Nilai Sun Protection Factor (SPF) Ekstrak Air dan Kloroform Daun Kelor (Moringa oleifera L.) Litta ‘Ifina; Fadilah Qonitah; Risma Sakti Pambudi
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 2 (2025): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i2.596

Abstract

Moringa (Moringa oleifera) is a plant that is easy to grow in lowlands that contains phenolic compounds and flavonoids that have the potential to be sunscreen. The purpose of this study is to determine the activity of sunscreen from water extract and chloroform of moringa leaves as seen from the SPF parameters. The process of making extracts by infusion and maceration methods. Testing of SPF values with the UV-Vis spectrophotometer method. The SPF (Sun Protection Factor) value was determined using a UV-Vis spectrophotometer by measuring absorbances from concentrations of 50 ppm, 100 ppm, 150 ppm, 200 ppm, and 250 ppm water extract solutions and chloroform moringa leaves at wavelengths (290-320 nm) every 5 nm intervals with ethanol pa as a blank. The calculation of the SPF (Sun Protection Factor) value uses the Mansyur equation. The experiments that have been carried out have obtained results that there is sunscreen activity with the highest SPF value in water extract with a concentration of 250 ppm of 7.97 (extra protection) and in chloroform extract with a concentration of 250 ppm of 8.72 (ultra protection). Based on this study, it can be concluded that chloroform extract has a higher SPF value content compared to moringa leaf water extract at the same concentration.
Comparison of Antibacterial Activities of Ethanol and Methanol Extracts of Early Flower Leaves (Clitoria Ternatea L.) against Escherichia Coli ESBL (Extended Spectrum Beta Lactamase) Susi Rahmawati; Abdul, Ahwan; Fadilah Qonitah
Jurnal Jamu Indonesia Vol. 7 No. 2 (2022): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v7i2.237

Abstract

Inappropriate use of antibiotics can lead to bacterial resistance. Extended Spectrum Beta Lactamase (ESBL) is a bacterium that is resistant to beta-lactam antibiotics such as penicillins, cephalosporins and monobactams. One example of this bacterium is Escherichia coli which can cause a number of diseases such as urinary tract infections, respiratory infections, sepsis and meningitis. The leaves of the telang flower (Clitoria ternatea L.) contain a number of compounds that have antibacterial activity which are expected to be an alternative for the treatment of infections caused by ESBL Escherichia coli. This study aims to determine the antibacterial activity of ethanol and methanol extract of telang flower leaves against Escherichia coli ESBL and to compare the activities of the two extracts. The test method is experimental, namely measuring the antibacterial activity of the extract using the disk diffusion method. The results of the phytochemical screening test conducted showed that the extract tested positive contained flavonoids, alkaloids, phenolics, saponins, tannins and terpenoids. The results of the research related to the antimicrobial activity of the concentrations of 25%, 50% and 100% methanol extract produced inhibition zone diameters of 7.4 mm, 7.8 mm and 8.1 mm, while the ethanol extracts were 7.3 mm, 7.4 mm. , 7.9 mm. The positive control used, namely gentamicin, produced an inhibition zone of 9.8 mm. These results indicate that the methanol and ethanol extract of telang flower leaves affected the growth of Escherichia coli ESBL and there was a difference in the antibacterial activity of the two extracts based on statistical analysis with the Anova test with p value <0.05.
Co-Authors Abdul, Ahwan abdul, ahwan Ahwan Abdul Litta ‘Ifina Pratiwi Maharani, Nurul Astia Wuri Reni Ariastuti Risma Sakti Pambudi Salwa Pratiwi SUSI RAHMAWATI