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Horasdia Saragih
Universitas Advent Indonesia
Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Physics Public Health Social Sciences Other

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Stabilisasi Sterik Polimer Non-Ionik Tween 80 pada Nanopartikel Senyawa Bioaktif Buah Kapulaga Saragih, Horasdia
Jurnal Fisika Unand Vol 15 No 2 (2026)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jfu.15.2.164-173.2026

Abstract

The bioactive compounds in cardamom fruit are highly beneficial to health, as they possess anticancer, antioxidant, antibacterial, anti-inflammatory, and antibiotic properties. Therefore, they have great potential to be developed as oral medicines in the future. However, they are highly hydrophobic and consequently insoluble in water. This poses an obstacle to their development. To overcome this problem, bioactive compounds from cardamom fruit have been synthesized into nanometer-sized particles (13.13-19.75 nm) and encapsulated with the nonionic polymer surfactant Tween 80. The results show that Tween 80 surfactant not only acts as an encapsulant for nanoparticles so that they can be dispersed in an aqueous medium, but also acts as a steric stabilizer so that the nanoparticles can remain stable for a long time. Four concentrations of bioactive compounds from cardamom fruit were used, namely: 6, 8, 10, and 12 mg to observe their effect on size stability. All nanoparticles produced from the four concentrations had excellent size stability.
Co-Authors Agus Subagio Agus Subagio Akhiruddin Maddu Albert Manggading Hutapea Albinur Limbong, Albinur Angelita, Flora Donn Richard Ricky Edy Supriyanto Edy Supriyanto Euis Sustini Ginting, Endru Saperlin Lawren Hasniah Aliah Hery Sutanto Ina, Febi Rambu Maman Budiman Maman Budiman Marissa Rijoice Mersi Kurniati Moehamad Barmawi Moehammad Barmawi Mohamad Barmawi Mohamad Barmawi Mohamad Barmawi Mohamad Barmawi Mohamad Barmawi Mohammad Barmawi Mujamilah Mujamilah Mujamilah Mujamilah Mujamilah Mujamilah Pearlyta Chrisophras Situmorang Pepen Arifin Pepen Arifin Pepen Arifin Pepen Arifin Pepen Arifin Pepen Arifin Pepen Arifin Ridwan Ridwan Ridwan Ridwan Rozi, Anisa Nurraeni RR. Ella Evrita Hestiandari Rumanti, Agustina Tri Sukirno Sukirno Sukirno Sukirno Sukirno Sukirno Tarigan, Andesmeta Winarti, Ratu Sesillia