Article Per Year (5 Year)
p-Index From 2020 - 2025
2.024
P-Index
This Author published in this journals
All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Pharmacon Jurnal Farmasi Sains dan Komunitas JFL : Jurnal Farmasi Lampung Jurnal Aisyah : Jurnal Ilmu Kesehatan Universitas Muhammadiyah Yogyakarta Undergraduate Conference Proceeding Prosiding Seminar Nasional Program Pengabdian Masyarakat Jurnal Farmasi Sains dan Praktis Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Sabtanti Harimurti, Sabtanti
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 10 Documents
Search

 1 
Pharmaceutical Installation Performance Analysis PKU Muhammadyah RSU Sragen with a Balance Scorecard Approach Setyawan, Indra Agus; Kusumawati, Wiwik; Harimurti, Sabtanti
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No S1 (2022): Suplement 1
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (681.93 KB) | DOI: 10.30604/jika.v7iS1.1222

Abstract

Research objectives: To determine the performance of the pharmaceutical installation of PKU Muhammadiyah Hospital Sragen based on a learning and growth perspective, which is viewed from job satisfaction, worker retention, work productivity and job training. Research Methods: This type of research is descriptive research with a quantitative approach. The sample used was 18 employees of the pharmacy installation of PKU Muhammadiyah Hospital Sragen according to the established criteria. Data analysis uses frequency distribution which is presented in tabular form. Research Results: Employee performance in terms of job satisfaction is included in the fairly satisfied category, meaning that employees are satisfied with income other than salary, promotions, co-workers, superiors to their work. Employee performance as seen from employee retention from 2017 to 2020 has the ability to keep employees from working in hospitals. Employee performance as seen from the training does not meet the training target, which is a minimum of two trainings per year. Approximately 61.11% or 11 employees who have attended training. Employee performance seen from productivity, the income earned by employees from 2017 to 2019 did not experience a significant change Abstrack: Tujuan penelitian: Untuk mengetahui kinerja instalasi farmasi RS PKU Muhammadiyah Sragen berdasarkan perspektif pembelajaran dan pertumbuhan, yang ditinjau dari kepuasan kerja, retensi pekerja, produktivitas kerja dan pelatihan kerja. Metode Penelitian: Jenis penelitian ini adalah penelitian deskriptif dengan pendekatan kuantitatif. Sampel yang digunakan yaitu 18 orang karyawan instalasi farmasi RS PKU Muhammadiyah Sragen sesuai dengan kriteria yang ditetapkan. Analisis data menggunakan distribusi frekuensi yang disajikan dalam bentuk tabel. Hasil Penelitian: Kinerja karyawan dilihat dari kepuasan kerjanya termasuk dalam kategori cukup puas, artinya karyawan merasa puas terhadap pendapatan selain gaji, promosi, rekan kerja, atasannya hingga pekerjaannya. Kinerja karyawan yang dilihat dari retensi pekerja sejak tahun 2017 hingga tahun 2020 memiliki kemampuan untuk menahan karyawannya agar tetap bekerja di rumah sakit. Kinerja karyawan yang dilihat dari pelatihan tidak memenuhi target pelatihan, yaitu minimum dua kali pelatihan setiap tahunnya. Sekitar 61,11% atau 11 orang karyawan yang sudah pernah mengikuti pelatihan. Kinerja karyawan yang dilihat dari produktivitasnya, pendapatan yang diperoleh karyawan dari tahun 2017 hingga 2019 tidak mengalami perubahan yang signifikan. Kesimpulan: Kinerja karyawan dalam prespektif pembelajaran dan pertumbuhan secara keseluruhan termasuk cukup baik.
Analisis Survei Pewarna Berbahaya Rhodamin B pada Kerupuk Berwarna Merah yang Beredar di Pasar Besar Kota Madiun Puspitasari, Adinda Putri Herlada; Harimurti, Sabtanti
Proceeding Universitas Muhammadiyah Yogyakarta Graduate Conference Vol. 1 No. 1 (2020): Armoring the Youth to Contribute to the SDGs
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (711.957 KB)

Abstract

Rhodamin B merupakan pewarna tekstil yang dilarang penggunaannya dalam makanan berdasarkan Peraturan Menteri Kesehatan Republik Indonesia No.239/MenKes/ Per/V/85, salah satunya kerupuk. Lokasi pengambilan sampel kerupuk adalah di Pasar Besar Kota Madiun. Sampel direndam dengan amonia untuk menarik zat pewarna Rhodamin B menggunakan benang wol, dilanjutkan dengan identifikasi menggunakan kromatografi lapis tipis (KLT). Pembacaan kadar Rhodamin B menggunakan spektrofotometri UV-Vis. Hasil penelitian menunjukkan bahwa dari tujuh sampel yang diperiksa dengan dua kali pengujian didapat enam sampel positif mengandung Rhodamin B dengan rentang kadar Rhodamin B 56,9 mcg/g sampai 335,3 mcg/g dan satu sampel negatif. Berdasarkan hasil penelitian ini, beberapa kerupuk yang beredar di Pasar Besar Kota Madiun kurang aman dikonsumsi, dengan kriteria warna yang mencolok karena dicurigai mengandung zat pewarna berbahaya bagi kesehatan.
SAGO STARCH AND SODIUM ALGINATE AS NATURAL CROSSLINKING FOR CAPSULE ALTERNATIVES Harimurti, Sabtanti; Mulyanti, Amelia Nur'afni; Kusnindyasita, Anisa; Widada, Hari; Febriansah, Rifki; Suwanda, Totok; Muhtadi, Muhtadi
Jurnal Farmasi Sains dan Praktis Vol 9 No 3 (September-December 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i3.8856

Abstract

Capsule shells are generally made from gelatin. The gelatin that is spread in the world is commonly derived from pigs. This animal is forbidden to be consumed by Muslims. This issue is due to the halal aspect. Sago starch and sodium alginate are halal materials that are capable of gelatinizing. This property made it able to be molded as a capsule. This research aims to determine the formula of sago and sodium alginate as a capsule and the evaluation. Three formulas were made with the ratio of sago and sodium alginate 100%: 0% (formula 1), 50%: 50% (formula 2), and 0%: 100% (formula 3). The capsule was manually molded using a food-grade stainless steel capsule mold. The size of the capsule, weight uniformity, swelling, and disintegration time were determined for a physical evaluation. SLD was used to determine the best formula, and the validation was done using One-sample T-test. The evaluations of the capsule shell were found ranged as follows: the size specifications were 21-22 mm, the body diameter was 6.1-7.2 mm, the cap diameter was 13.6-13.8 mm, weight uniformity was 0.10-0.26 gram, the swelling test was 433-1583%, and the disintegration time was 10.20-14.43 minutes. The best formula based on the SLD of the experiment was formula 3, which are two parameters that met the requirements, i.e., swelling and disintegration time. The sago and sodium alginate were crosslinked, and the capsule was made. However, the performance dislike of gelatin capsules. Continued research shall be done to find the optimum formula and its characteristics for alternative material on halal capsules.
OPTIMIZATION OF pH VALUE AND GEL VISCOSITY IN PORANG TUBER CAPSULE SHELL FORMULATION Maulana, Riza; Muhtadi; Suhendi, Andi; Prasetya, Farid Adi; Harimurti, Sabtanti; Hamzah, Hasyrul
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 3 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i3.1212

Abstract

The porang tuber contains glucomannan compounds that can expand into a gel so that it has the potential to be used as the main ingredient of capsule shells. This research aims to optimize the pH and viscosity values that can affect the consistency of the capsule shell produced. The method used in the manufacture of capsule shells is the dipping pen method, while the optimization method carried out is trial and error by making 3 formulas by combining glycerin and PEG 400. The results obtained by the gel mass formed by the glycerin-PEG 400 gelling agent have a viscosity value of 586.67 dPas and a pH value of 6.02 can provide a gel mass that is easy to mold capsule shells and obtain capsule shells with elastic characters.  The results indicate optimal viscosity and pH values to obtain a gel mass that is easy to mold capsule shells with good organoleptic characteristics. Keywords:  Glucomannan, pH, viscosity, capsule shell.
Pencerdasan Melalui Penyuluhan Pengelolaan Obat Dagusibu Sebagai Peningkatan Kualitas Kesehatan Al Falih, Muhamad Rafli; Rakhmat, Devanzka Jaifar; Triyantoro, Ahmad Fauzan; Lioni, Kenza Septia; Indartuti, Kartika; Bayuaji, Reihan Padantya; Khairunnisa, Rahmadina Safa; Putri, Adelia Zenia; Febyanti, Dyah Ajeng; Fatha, Husein Rahman; Harimurti, Sabtanti
Prosiding Seminar Nasional Program Pengabdian Masyarakat Vol. 8 No. 1 (2025): Rekonstruksi Pendidikan di Indonesia
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ppm.81.1269

Abstract

The background of this study is the high rate of drug abuse in the community, which can cause adverse health effects if not properly managed. Counseling on the proper management and use of drugs is very important to increase public understanding of how to use drugs safely and effectively. One of the efforts made to achieve this goal is through the DAGUSIBU (Daya Penggunaan Obat Secara Bijak untuk Umum) program, which aims to educate the public on how to manage and use drugs properly. This study used a quantitative method with a pre-post test experimental design. The respondents of this study were 27 community members who attended DAGUSIBU counseling, and data were collected through questionnaires filled out before and after counseling was conducted. Data analysis was carried out with statistical tests to determine differences in the level of knowledge of respondents before and after counseling. The results showed an increase in participants' knowledge. The average score of participants' knowledge in the pre-test was 76.375, which increased to 81.375 in the post-test. Most respondents reported that they better understood how to choose appropriate medicines and how to use them wisely. The 47% increase in post-test scores indicates the effectiveness of the program in improving community understanding of medicine management. In conclusion, the DAGUSIBU counseling program was effective in improving the community's knowledge on drug management, thereby reducing the risk of drug abuse and supporting better public health.
Formulation and Evaluation of Pulp Devitalization Paste Combination of Jatropha Curcas L. and Piper Crocatum Leaves Extract Damarwati, Vella Lailli; Wahid, Rahmat A Hi; Primasari, Dyani; Harimurti, Sabtanti; Labibah, Lana; Syahrani, Syahrani; Krisridwany, Annisa
Media Farmasi: Jurnal Ilmu Farmasi Vol. 19 No. 2: September 2022
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v19i2.24041

Abstract

Dental caries require operative techniques such as pulp devitalization, but pulp devitalization materials that are often used by dentists have serious adverse effects that need to be considered, such as gingival injury and alveolar bone necrosis. Hence, the aim of the present study was to develop natural ingredients as an alternative to pulp devitalization from a combination of Jatropha curcas (Jatropha curcas L.) and red betel leaf extract (Piper crocatum) in the form of a paste and then conducting physical evaluation tests, Cyclooxygenase-2 (COX-2) tests, and also histopathological picture tests to the sample. The formulation of the pasta sample was carried out by the trituration method.  Formulation I (FI) contained 25% of Jatropha resin, 0.25% red betel leaf extract, and 25% Jatropha resin, 0.5% red betel leaf extract for Formulation II (FII). The paste produced was then evaluated for physical properties which consisted of organoleptic, homogeneity, pH, spreadability, adhesion, and anti-inflammatory power using test animals with COX-2 expression number parameters. The FI and FII treatment groups had met the requirements as paste formula. In the COX-2 expression test, FI has a COX-2 expression percentage value of 0.38% and a COX-2 suppression percentage value of 0.62%, while FII has a COX-2 expression percentage value of 0.59% and a COX-2 expression percentage of 0.59% and suppression of COX-2 of 0.41%. The optimal concentration of the paste formulation is the paste with a combination of 25% jatropha latex and 0.25% red betel leaf extract had been shown to have potential as an alternative to pulp devitalization
Synthesis and Characterization of Ethanolic Extract of Red Betel Leaf as an Antiseptic Gel Harimurti, Sabtanti; Hidayaturahmah, Rizky; Arsito, Puguh Novi; Febriansah, Rifki; Widada, Hari
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.006555

Abstract

Hand hygiene is one way to maintain health. There are several ways to clean hands, namely by washing hands and applying a hand sanitizer. The use of hand sanitizer is increasing due to its practical nature. Utilizing natural materials for preparing hand sanitizer widely available around us will be beneficial, one of which is red betel leaf which some people of Indonesia empirically use for antiseptic. This study aims to develop antiseptic gel preparations with ethanolic extracts from red betel leaves. The extraction was done using maceration with 70% ethanol solvent. The formula for choosing a carbomer as a gelling agent with the red betel leaf extract concentration was 0%, 2.5%, 5%, 10%, and 15%. The assessments of the gel were physical and antiseptic evaluations. The physical evaluations included an organoleptic, pH, viscosity, adhesion, and dispersion tests. The antiseptic activity was determined by a replica method. The physical evaluation results of red betel gel revealed that the higher the red betel leaf extract levels are, the darker the green color will be, and the lower the pH and viscosity will be. Furthermore, the antiseptic activity showed that red betel extract gel effectively reduced the number of bacterial colonies. 
Purification of Curcumin Derivate (1,5-bis(4’-hydroxy-3’-methoxyphenyl)-1,4-pentadien-3-on) Using Chromatotron Harimurti, Sabtanti; Fadhilah, Alfan; Widada, Hari; Damarwati, Vella Lailli
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23593

Abstract

Curcumin derivate with IUPAC name 1,5-bis(4’-hydroxy-3’-methoxyphenyl)-1,4-pentadien-3-on is also known as Gamavuton-0 (GVT-0) reported has an activity as anti-inflammation and anti-cancer. GVT-0 can be synthesized using vanillin and acetone as starting material by aldol condensation. Purification process of GVT-0 after synthesis usually was done using maceration. This method resulting un-pure GVT-0, therefore, another separation technique of Chromatotron was chosen. This research aims to investigate the effectiveness of Chromatotron towards the purity of GVT-0. The study was started by GVT-0 synthesis. The synthesis was using 4.4 mole of vanillin and 1 mole acetone as the raw material. Microwave irradiation was used as the energy source. Isolation of GVT-0 using hot water maceration. Further, the purification of GVT-0 was conducted using Chomatotron. First step of purification using Chomatotron was preparing best ratio between hexane and chloroform as solvent to remove vanillin. Further, the best combination of solvent was used to separate all the vanillin remaining in the bulk of GVT-0. Last step after all vanillin was removed, the GVT-0 remining in the silica was elucidated using chloroform. The purity was evaluated using Melting-point analysis and Thin Layer Chromatography (TLC) with four different mobile phases. Based on the data of melting point and TLC, a pure GVT-0 was obtained. The Chomatotron may be recommended for purification of GVT-0, however this method consumes a lot of organic solvent that may need to be improved in the future with more environmentally process
Bromelain-Extracted of Virgin Coconut Oil: Physical and Chemical Stability in Different Temperature During the Storage Harimurti, Sabtanti; Sukamdi, Dyani Primasari; Widada, Hari; Sari, Hasna Fadia; Amid, Azura
Borneo Journal of Pharmacy Vol. 7 No. 2 (2024): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v7i2.6857

Abstract

The bromelain-enzymatic reaction is applied in virgin coconut oil (VCO) production. Hydrolysis of the emulator by bromelain enzyme in coconut milk during fermentation maximized further the separation of oil and water. In the higher demand for VCO in many industries, the VCO stability during transportation and storage must be evaluated.  The research aims to evaluate the physical and chemical stability of the effect of temperature in the storage. VCO's physical and chemical stability was evaluated under two different temperature and storage periods: an elevated temperature of 50°C for 10 days and room temperature (27-30°C) for 50 days. The storage was conducted in a clear glass bottle. The evaluation was based on physical and chemical stability tests before and after storage, including organoleptic, pH changes, density, viscosity, acid number, peroxide number, and saponification number. Based on the data, the quality of the VCO after storing at 50°C for 10 days and 27-30°C for 50 days was found to be changed for pH, specific gravity, viscosity, acid number, peroxide number, saponification number, while for the appearance was found to be no changes. The VCO was very sensitive to environmental effects. Therefore, it is necessary to find the best storage chamber and temperature for stabilizing the VCO.
Formulasi Dan Penentuan Nilai SPF Lip Balm Kombinasi Ekstrak Kulit Nanas (Ananas comusus L. Merr) dan Kulit Wortel (Daucus carota L.) Sukamdi, Dyani Primasari; Nurjanah, Cut Intan Ayu; Harimurti, Sabtanti; Krisridwany, Annisa; Amid, Azura; Haresmita, Perdana Priya
JFL : Jurnal Farmasi Lampung Vol. 14 No. 2 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/tqd48s21

Abstract

Lips are susceptible to ultraviolet (UV) exposure because they lack melanin, sweat glands, and hair follicles. To protect and moisturize lips, lip balm is widely used; however, it generally contains synthetic ingredients that can cause side effects. Therefore, a safe and effective natural-based alternative is needed. Pineapple peel (Ananas comusus L. Merr.) contains flavonoids and tannins that function as natural sunscreens. In contrast, carrot peel (Daucus carota L.) is rich in β-carotene, vitamin E, and flavonoids with antioxidant and natural coloring properties. The combination of these ingredients is considered complementary and has the potential to be used as natural active components in lip balm formulations. This study aims to determine the formulation and SPF value of lip balms containing pineapple and carrot peel extracts as UV protection agents. Four formulations were prepared: F0 (0% extract), F1 (10% pineapple peel extract), F2 (10% carrot peel extract), and F3 (combination of both extracts). The evaluation included organoleptic testing, homogeneity testing, stability testing, determination of the melting point, pH measurement, and SPF testing. Data were analyzed using the Kruskal-Wallis test method. The results showed that all formulations met the characteristics of a good lip balm, with SPF values of 1.028, 8.791, 8.949, and 25.672, respectively. Formulation F3 showed the highest SPF value with “ultra” protection, indicating strong potential as a natural UV-protective lip balm. Keywords:  Pineapple peel, carrot peel, lip balm, formulation, SPF value.
Co-Authors Al Falih, Muhamad Rafli Amid, Azura Andi Suhendi Arsito, Puguh Novi Bayuaji, Reihan Padantya Fadhilah, Alfan Faray, Kartini Farid Adi Prasetya Fatha, Husein Rahman Febyanti, Dyah Ajeng Hamzah, Hasyrul Hari Widada, Hari Hidayaturahmah, Rizky Indartuti, Kartika Khairunnisa, Rahmadina Safa Krisridwany, Annisa Kurniawan, M. Fariez Kusnindyasita, Anisa Labibah, Lana Lioni, Kenza Septia MAULANA, RIZA Muhtadi Muhtadi Muhtadi Mulyanti, Amelia Nur'afni Nurjanah, Cut Intan Ayu Perdana Priya Haresmita, Perdana Priya Primasari, Dyani Puspitasari, Adinda Putri Herlada Putri, Adelia Zenia Rakhmat, Devanzka Jaifar Rifki Febriansah Sari, Hasna Fadia Setyawan, Indra Agus SYAHRANI SYAHRANI Totok Suwanda Triyantoro, Ahmad Fauzan Vella Lailli Damarwati Wahid, Rahmat A Hi Wiwik Kusumawati, Wiwik