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All Journal Padjadjaran Journal of Dentistry Journal of Case Reports in Dental Medicine MDJ (Makassar Dental Journal)
Sri Oktawati, Sri
Faculty of Dentistry, Hasanuddin University
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Relationship between peri-implantitis and diabetes mellitus: Hubungan antara peri-implantitis dan diabetes melitus Bhuana, Alikha Afridha Tripuspira Chandra; Oktawati, Sri
Makassar Dental Journal Vol. 13 No. 3 (2024): Volume 13 Issue 3 Desember 2024
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v13i3.1120

Abstract

Diabetes mellitus is a chronic metabolic disorder that causes sufferers to be unable to regulate their blood sugar levels. Dental implant treatment causes the oral mucosa to become prone to inflammation. This condition has the potential to trigger disease at the site of implant placement such as peri-implantitis. This article examines the prevalence, mechanism, and management of peri-implantitis in patients with DM. Data were collected by literature searches on Pubmed, Science Direct and Cochrane Li-brary for articles published in 2017-2024, using the PRISMA method for systematic and literature reviews. Seven articles were synthesised through selection and filtering methods. The articles found all had a correlation with peri-implantitis, peri-implant di-sease and DM either through healing, micro organisms, and severity as well as potential treatment modalities. It was conclu-ded that there are several conditions that may have an association between DM and peri-implantitis and peri-implant disease.
Effect of glycaemic control in patients with diabetes mellitus on periodontal disease severity: Efek kontrol glikemik penderita diabetes melitus terhadap keparahan penyakit periodontal Fitriani, Juli; Oktawati, Sri
Makassar Dental Journal Vol. 13 No. 3 (2024): Volume 13 Issue 3 Desember 2024
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v13i3.1199

Abstract

Periodontal disease is a chronic inflammation that can affect the supporting tissues of the teeth. One of the risk factors that ag-gravate periodontal disease is diabetes mellitus (DM). This article examines the effect of glycaemic control in patients with DM on the severity of periodontal disease. Literature search was conducted using various electronic databases (Pubmed, google scholar and google scholar), with the keywords glycemic control AND periodontal disease; periodontal disease AND diabetes mellitus, insulin, complication of diabetes mellitus. Literature published in the last 5 years in Indonesian and English. Several studies sug-gest that DM is a risk factor for periodontal disease and there is a reciprocal relationship between DM disease and periodontal disease severity. It was concluded that patients with uncontrolled glycaemic can aggravate periodontal disease. DM control by performing periodontal treatment can prevent the severity of periodontal disease and DM disease.
Treatment of dental polyclinic -induced gingivitis caused by secondary caries: a case report Dinyati, Maisaroh; Mapanggara, Surijana; Adam, Andi M.; Oktawati, Sri
Journal of Case Reports in Dental Medicine Vol 1, No 1 (2019)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (975.053 KB) | DOI: 10.20956/jcrdm.v1i1.84

Abstract

Objective: This case report aims to present gingival therapy with gingivectomy due to secondary caries and overhanging filling.Methods: A 21-year-old male patient come to the periodontal clinic for treatment. The initial examination revealed deep probing pocket depth with sulcus bleeding at 11, 12, 21 and 22.  Teeth 34, 36, 37 were extracted. Patients was in a good health, smoker, and didn’t take any medication. The patient had scalling a week ago but the gingiva remains enlargement. Periapical radiograph showed bone in good density. Initial treatment performed by non-surgery treatment included Scalling and Root Planing (SRP) and 0.2% chlorhexidine solution twice daily for one week. Gingivectomy with conventional blade. The result of control showed reduced enlarged of gingiva and patient feel satisfied with the treatment. Control one week after surgery. After being cured clinically, composite filling applied on teeth 11 and 21.Results: Gingivitis caused by secondary caries, because of bacterial invasion of caries to the gingival mucosa. Gingivitis therapy performed by gingivectomy, the removal of amount of the hyperplated gingival mucosa. Conventional gingivectomy is an option of gingival enlargement therapy.Conclusion: The aim of gingival therapy is to eliminate inflammatory process and prevent the progression of gingival disease. Gingival disease including gingival enlargement or gingivitis. Gingivitis can be caused by various factors such as secondary caries and overhanging filling. Keywords:  Gingival enlargement, Gingivectomy, Seconder caries.
Amlodipine effect as a trigger factor for massive growth of giant gingival overgrowth: A case report Ibriana, Ibriana; Zulistiana, Ditha; Nurfaizah, Tira; Oktawati, Sri
Journal of Case Reports in Dental Medicine Vol 6, No 2 (2024)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v6i2.236

Abstract

Introduction: Drug-induced gingival overgrowth has been widely reported, especially in hypertensive patients. Amlodipine is a type of hypertension drug that often triggers gingival overgrowth. This case is made worse by poor oral hygiene conditions which cause massive growth and enlargement of the gingiva. Case Report : A 63 year old man came to Hasanuddin University Dental and Oral Hospital with complaints of enlarged gums in the palate area and right cheek. The patient suffers from hypertension and has been regularly taking amlodipine for the past 1 year. Enlarged gums make it difficult for patients to clean their teeth and mouth, resulting in patients experiencing bad breath and difficulty chewing on the side that they complain about due to loose teeth. Enlarged gums are not painful, but often bleed when touched by a toothbrush or food.Conclusion : Treatment of gingival overgrowth by substitution of hypertension drugs, strict oral hygiene control, and surgical intervention through gingivectomy and flap surgery procedures showed satisfactory results after 5 months of follow-up.
Epulis due to occlusion trauma, a combination surgery of excision and open flap debridement : A case report Chandra, Adelia; Fitriani, Juli; Afrini, Nurul; Oktawati, Sri
Journal of Case Reports in Dental Medicine Vol 6, No 2 (2024)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v6i2.237

Abstract

Introduction : Gingival Enlargement can happen due to variable reasons, one of them being occlusion trauma (biting), this is due to the fact that the enlargement happened as a trauma response from chronic irritation. One of the main concerns of epulis in the anterior region is the potential of exacerbated conditions due to repeated contact, thus causing further inflammation in which will cause bone damage, furthermore aesthetic is also a concern as it discernible as it is located in the smile area of the patient. Case Report : A 30 year old female patient was presented to Hasanuddin Dental Hospital due to swollen gum in the lower front teeth, patient also complained that it bleeds easily. Patient stated that the swelling happened when the patient was eating an apple and the patient’s gum was torn from biting and was exacerbated when the incident happened again when eating, during which the swelling happened. Patient first visited a health facility before being referred and was given antibiotics, during which the gum is still bleeding and even bled during normal conversation. Patient routinely visited the dentist and last visited 3 months ago for Scalling, furthermore patients denied any systemic diseases and allergies. Conclusion : Epulis should be handled immediately with excisional surgery, furthermore, upon finding bone defects in the overgrown area, surgical debridement should be done as to prevent further damage to the alveolar structure in order to circumvent potential tooth mobility
Demineralized dentin matrix (DDM) from human teeth increases osteoblasts and type i collagen density after tooth extraction: an experimental study Dewi, Renie Kumala; Oktawati, Sri; Gani, Asdar; Suhartono, Eko; Hamrun, Nurlinda; Ganesh, Rajendran; Sapphira, Nadira; Aurenada, Syabita
Padjadjaran Journal of Dentistry Vol 37, No 1 (2025): March 2025
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol37no1.59205

Abstract

Introduction: Post-extraction cavities must be promptly treated to minimize alveolar ridge resorption. Various bone graft materials can be used to encourage bone regeneration in perialveolar defects. Demineralized Dentin Matrix (DDM) is a bone graft material found in human tooth dentin containing type I collagen. The content of DDM is expected to show an increase in mediators that form bone, such as osteoblasts, thereby accelerating the bone healing process. The study aims to analyze the effect of DDM on osteoblast count and type I collagen density during post-extraction bone healing. Methods: This true experimental study used guinea pigs with extracted left mandibular incisors. Sockets were filled with (1) polyethylene glycol gel (control group, n=9) or (2) DDM gel (treatment group, n=9). The gel was inserted into the socket until it was full and then sutured with non-absorbable silk. The guinea pigs were euthanized on days 7, 14, and 21 for osteoblast counting and type I collagen density measurement. One-way ANOVA was used to assess osteoblast numbers, while the Kruskal-Wallis test was applied to analyze type I collagen density. Results: The treatment group exhibited a higher osteoblast count on day 7 (48.73), day 14 (79.00), and day 21 (89.66) compared to the control group (day 7: 33.00, day 14: 59.6, day 21: 78.27). A statistically significant difference was observed between the treatment and control groups in osteoblast count (p = 0.000) and type I collagen density (p = 0.009). Conclusion: DDM increases osteoblast numbers and type I collagen density on days 7, 14, and 21 post-extraction, potentially enhancing bone remodeling
The impact of chitosan derived from black soldier fly (Hermetia illucens) pupae on bone remodeling post-tooth extraction: an in vivo study Maula, Ni’mal; Waty, Marsela Umbar; Dewi, Renie Kumala; Oktawati, Sri; Gani, Asdar; Suhartono, Eko; Ganesh, Rajendran
Padjadjaran Journal of Dentistry Vol 37, No 1 (2025): March 2025
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol37no1.59308

Abstract

Introduction: Bone defects or alveolar sockets commonly occur after tooth extraction. Black Soldier Fly (BSF) pupae contain 35% chitin, which can be converted into chitosan. This study aims to analyze the effect of BSF pupae chitosan gel on the number of osteoblasts and osteoclasts in post-extraction sockets. Method: This study employed a true experimental design. The left mandibular incisor of guinea pigs was extracted. In the control group (n=9), the socket was filled with polyethylene glycol (PEG) gel as a placebo, while in the treatment group (n=9), the socket was filled with BSF pupae chitosan  gel. The gel was applied until the socket was full, followed by suturing with non-absorbable silk. Euthanasia was performed on days 7, 14, and 21 to evaluate the number of osteoblasts and osteoclasts. Data were analyzed using one-way Anova. Results: The osteoblast count in the treatment group increased on day 7 (52.20 ± 1.90), day 14 (91.53 ± 1.00), and day 21 (104.13 ± 5.33) compared to the control group:  day 7 (39.80 ± 5.43), day 14 (61.13 ± 1.10), and day 21 (82.60 ± 2,11). The number of osteoclasts decreased in both groups: in the control group on day 7 (9.83 ± 0.35), day 14 (12.80 ± 0.72), and day 21 (2.46 ± 0.11); and in the treatment group on day 7 (4.86 ± 1.51), day 14 (9 ± 0.34), and day 21 (2.66 ± 0.11). Statistical analysis revealed significant differences in osteoblast and osteoclast counts between the treatment and control groups (p = 0.000). Conclusion: The application of chitosan BSF pupae gel can increase osteoblast numbers and decrease osteoclast numbers after tooth extraction, potentially accelerating bone formation and offering benefits for future bone regeneration.
Co-Authors Afrini, Nurul Andi M. Adam, Andi M. Asdar Gani, Asdar Aurenada, Syabita Bhuana, Alikha Afridha Tripuspira Chandra Chandra, Adelia Dewi, Renie Kumala Dinyati, Maisaroh Eko Suhartono Fitriani, Juli Ganesh, Rajendran Hamrun, Nurlinda Ibriana, Ibriana Mapanggara, Surijana Maula, Ni’mal Nurfaizah, Tira Sapphira, Nadira Waty, Marsela Umbar Zulistiana, Ditha