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PROBIOTIK MENINGKATKAN KONSENTRASI HEMOGLOBIN PADA TIKUS PUTIH YANG DIINDUKSI LIPOPOLISAKARIDA ESCHERICHIA COLI Sari, Efris Kartika; Wihastuti, Titin Andri; Ardiansyah, Wahyu
Majalah Kesehatan FKUB Vol 5, No 1 (2018): Majalah Kesehatan Fakultas Kedokteran
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.881 KB) | DOI: 10.21776/ub.majalahkesehatan.005.01.3

Abstract

Infeksi bakteri Escherichia coli (E. coli) dapat menyebabkan gangguan sistem hematologi, di antaranya berupa penurunan konsentrasi hemoglobin. Konsumsi probiotik dianggap sebagai salah satu upaya untuk meningkatkan sintesis hemoglobin. Penelitian ini bertujuan untuk mengetahui pengaruh Lactobacillus spp. terhadap konsentrasi hemoglobin pada tikus putih (Rattus norvegicus) yang diinduksi oleh lipopolisakarida (LPS) E. coli. Rancangan penelitian ini adalah true experimental dengan desain randomized post test only control group. Dua puluh satu ekor tikus putih dibagi ke dalam tiga kelompok yaitu: (1) kelompok tikus tanpa perlakuan sebagai kontrol negatif (n = 7), (2) kelompok tikus yang diinduksi LPS E. coli (n = 7), dan (3) kelompok tikus yang dipapar Lactobacillus spp. dan diinduksi LPS E. coli (n = 7). Konsentrasi hemoglobin diukur dengan metode oksihemoglobin. Hasil penelitian menunjukkan perbedaan  konsentrasi hemoglobin antara kelompok tikus dengan paparan probiotik dan diinduksi LPS E. coli (8,9±0,3 mmol/L) dibandingkan dengan kelompok kontrol negatif (8,0±0,8 mmol/L), dan kelompok yang hanya diinduksi LPS E. coli (8,4±0,5 mmol/L) (p < 0,05). Disimpulkan bahwa Lactobacillus spp. dapat meningkatkan konsentrasi hemoglobin pada tikus putih yang diinduksi LPS E. coli. Kata kunci: hemoglobin, Lactobacillus spp., lipopolisakarida E. coli
Tinjauan Literatur :PERBANDINGAN qSOFA DAN SIRS DALAM MENGIDENTIFIKASI PASIEN DENGAN SEPSIS DAN MEMPREDIKSI MORTALITASNYA: REVIEW ARTIKEL Sari, Efris Kartika
Majalah Kesehatan FKUB Vol 6, No 4 (2019): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (426.73 KB) | DOI: 10.21776/ub.majalahkesehatan.2019.006.04.7

Abstract

Sepsis merupakan penyebab utama kondisi sakit kritis dan mortalitas di dunia. Kondisi sepsis membutuhkan identifikasi segera karena penundaan identifikasi sepsis dapat berakibat pada peningkatan angka mortalitas pasien. Review artikel ini bertujuan untuk menganalisis perbandingan qSOFA dan SIRS dalam mengidentifikasi pasien dengan sepsis dan memprediksi mortalitasnya. Artikel didapatkan melalui pencarian menggunakan online database yaitu PubMed dengan menggunakan kata kunci qSOFA, SIRS, sepsis. Hasil pencarian mengidentifikasi hasil yang relevan dengan kata kunci sejumlah 35 artikel, kemudian dipilih 9 artikel untuk dikaji. Hasilnya terdapat satu studi pada 886 pasien yang menyatakan bahwa qSOFA dan SIRS belum optimal dalam mengidentifikasi sepsis. Terdapat dua studi dengan jumlah total 3.542 pasien yang menyatakan bahwa kriteria SIRS lebih baik dalam mengidentifikasi sepsis dan memprediksi mortalitas pasien. Selanjutnya, terdapat enam studi dengan jumlah total 167.172 pasien yang menyatakan keunggulan qSOFA dibandingkan dengan SIRS dalam mengidentifikasi sepsis dan memprediksi mortalitas pasien. Skor qSOFA lebih unggul dari kriteria SIRS dalam mengidentifikasi pasien sepsis dengan disfungsi organ yang berisiko tinggi mengalami kematian, sedangkan kriteria SIRS lebih unggul dari skor qSOFA dalam mengidentifikasi pasien sepsis yang belum mengalami disfungsi organ dan berisiko rendah mengalami kematian.   
HUBUNGAN SKOR SOFA DENGAN MORTALITAS PADA PASIEN SAKIT KRITIS Sari, Efris Kartika; Hayati, Yati Sri; Rokhmawati, Nila Lestari
Majalah Kesehatan FKUB Vol 8, No 3 (2021): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.majalahkesehatan.2021.008.03.4

Abstract

Sepsis merupakan suatu kondisi yang berisiko meningkatkan morbiditas dan mortalitas pasien sakit kritis. Gugus Tugas Sepsis-3 merekomendasikan Skor Sequential (Sepsis-related) Organ Failure Assessment (SOFA) untuk mengidentifikasi kondisi sepsis pada pasien sakit kritis. Penelitian ini bertujuan untuk mengetahui hubungan skor SOFA dengan mortalitas pasien sakit kritis di ruang rawat intensif Rumah Sakit dr. Saiful Anwar Malang. Penelitian ini merupakan penelitian kohort retrospektif yang menggunakan data sekunder berupa rekam medik pasien. Skor SOFA dihitung pada saat pasien masuk ke ruang rawat intensif. Sejumlah 115 rekam medik yang lengkap yaitu memenuhi kebutuhan perhitungan skor SOFA dianalisis. Hasil penelitian menunjukkan nilai rata-rata skor SOFA pasien adalah 7,25±3,85, dengan mortalitas pasien di ruang rawat intensif sebesar 55,6%. Uji statistik menunjukkan perbedaan yang bermakna antara skor SOFA pasien yang hidup dan yang meninggal (p < 0,05), dan ada hubungan antara skor SOFA dengan mortalitas (p < 0,05). Disimpulkan bahwa skor SOFA saat pasien masuk berhubungan dengan mortalitas pasien sakit kritis di ruang rawat intensif. 
Hubungan Sleep Hygiene Terhadap Tingkat Insomnia pada Lanjut Usia Setyoadi, Setyoadi; Purnamawati, Ni Putu Ika; Sari, Efris Kartika
Jurnal Keperawatan Malang Vol 8 No 1 (2023): Jurnal Keperawatan Malang (JKM)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat STIKes Panti Waluya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36916/jkm.v8i1.197

Abstract

Latar belakang: Insomnia merupakan gangguan tidur yang paling sering dialami oleh lanjut usia. Insomnia dapat disebabkan oleh berbagai faktor dan salah satunya adalah kebiasaan sebelum tidur (sleep hygiene). Terdapat 6 komponen yang dinilai dalam kebiasaan sebelum tidur yaitu: pola tidur, penggunaan tempat tidur, tingkat aktivitas, kondisi lingkungan, kondisi psikologi dan diet (konsumsi kopi). Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara kebiasaan sebelum tidur dengan derajat insomnia pada lanjut usia di Posyandu Lansia Kelurahan Tulusrejo Wilayah Kerja Puskesmas Kendalsari Kota Malang. Metode: Desain penelitian yang digunakan adalah observasional melalui pendekatan cross sectional. Sampel dalam penelitian ini adalah 36 lansia lansia yang mengalami insomnia dan dipilih dengan metode purposive sampling. Teknik analisa data menggunakan uji korelasi Spearman Rank. Hasil: Hasil uji statistik didapatkan p value 0.000 dan koefisien korelasi (r) = 0.773 yang artinya terdapa hubungan antara kebiasaan sebelum tidur sengan derajat insomnia pada lansia, dengan arah korelasi posotif (+) yang artinya semakin baik kebiasaan sebelum tidur maka semakin rendah derajat insomnia yang dialami oleh lanjut usia. Kesimpulan:Terdapat hubungan antara kebiasaan sebelum tidur (sleep hygiene) terhadap tingkat insomnia pada usia lanjut. Saran yang dapat diberikan untuk penelitian ini yaitu kader posyandu dapat memberikan edukasi kepada lansia mengenai kebiasaan sebelum tidur yang baik pada lansia yang mengalami insomnia
Efforts To Enhance Mental Health Among School-Aged Children During The Covid-19 Pandemic Through The Teacher And Parent Empowerment Hidayah, Ridhoyanti; Nova, Renny; Sari, Efris Kartika
Journal of Innovation and Applied Technology Vol 8, No 2 (2022)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jiat.2022.008.02.10

Abstract

School-aged children, as a developmental stage, are a group at high risk for mental health issues, particularly during this pandemic of COVID-19. Children may be perpetrators, witnesses, or victims of violence or irregularities perpetrated directly or through social media. This community service activity is designed to improve the mental health of children during the COVID-19 pandemic through early detection, prevention, and early treatment of mental health issues through parental and teacher empowerment programs. When children learn online and do more activities at home with their families, there are many factors that affect children's mental health. This is not widely known by the school, teachers, counselors, and parents clearly, which results in the state of the child getting worse. Through an empowerment program, they can discover early deviations that occur and take preventive measures with early treatment efforts during the COVID-19 pandemic.
Effect Of Health Education Model BASNEF On Knowledge And Compliance With Hypertension Diet In Elderly With Hypertension Setyoadi; Sari, Efris Kartika; Larasati, Intan
Journal of Rural Community Nursing Practice Vol. 1 No. 1 (2023): March
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jrcnp.v1i1.70

Abstract

Hypertension is a disease that mostly affects the elderly, this is due to unhealthy lifestyle changes, easy fast food, and excessive salt and fat consumption. Poor knowledge and adherence to the hypertension diet make the elderly not follow the hypertension diet properly. This study aimed to analyze the effect of the BASNEF model of health education on dietary knowledge and adherence in elderly people with hypertension. This study used Quasi-experimental one group pre-test and post-test design. The study population was elderly with hypertension taken by purposive sampling method, a total of 40 people with the criteria of being able to read, carry out activities independently, and live with family. The instrument used to measure variables is a questionnaire and data were analyzed using the Wilcoxon test. The average value obtained for knowledge of the hypertension diet increased by 14.78 and adherence to the hypertension diet also experienced an increase in the average value of 44.53. The results of the Wilcoxon test showed that there was an effect of the BASNEF model of health education on knowledge and adherence to the hypertension diet in elderly people with hypertension which was significant with p<0.05. The BASNEF method of health education can be an alternative to increasing knowledge and adherence to hypertension among elderly people in the community.
Impact of Perceived Vulnerability and Benefits on Adolescent Smoking Cessation Motivation Setyoadi; Aisyana, Lala; Sari, Efris Kartika; Ismail, Dina Dewi Sartika Lestari
Journal of Rural Community Nursing Practice Vol. 3 No. 1 (2025): March
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jrcnp.v3i1.404

Abstract

Background: Most smoking among adolescents aged 15-19 years is associated with a psychosocial crisis, as they are still searching for their identity. Factors such as perceived vulnerability and perceived benefits can lead adolescents to start smoking. Purpose: The purpose of this study was to determine the relationship between perceived vulnerability and perceived benefits and motivation for smoking cessation among adolescents. Methods: The research design uses an analytical observational design with a cross-sectional approach. The research sample consisted of adolescent smokers selected using a cluster random sampling technique, resulting in 136 participants. Data for variables were collected using the Perceived Vulnerability to Disease (PVD), Perceived Risks and Benefits Questionnaire (PRBQ), and Smoking Cessation Motivation Questionnaire (Q-MAT), which were modified by the researchers and tested for validity and reliability. The research data were analyzed using the Spearman Rank Test. Results: The results showed that 97.8% of participants had a positive perceived vulnerability, 97.1% had a positive perceived benefit, and 71.3% had a high motivation for smoking cessation. There was a significant relationship between perceived vulnerability and perceived benefits with motivation for smoking cessation, with a significant p-value of 0.000 and correlation values of +0.478 and +0.643. Conclusions: Adolescents' motivation to quit smoking is shaped by their awareness of health risks and the benefits of quitting, such as improved well-being and financial savings. Nursing-based interventions, including counseling, support groups, and school health campaigns, play a crucial role in reinforcing this motivation and ensuring long-term cessation.
Effect Of Health Education Model BASNEF On Knowledge And Compliance With Hypertension Diet In Elderly With Hypertension Setyoadi; Sari, Efris Kartika; Larasati, Intan
Journal of Rural Community Nursing Practice Vol. 1 No. 1 (2023): March
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jrcnp.v1i1.70

Abstract

Hypertension is a disease that mostly affects the elderly, this is due to unhealthy lifestyle changes, easy fast food, and excessive salt and fat consumption. Poor knowledge and adherence to the hypertension diet make the elderly not follow the hypertension diet properly. This study aimed to analyze the effect of the BASNEF model of health education on dietary knowledge and adherence in elderly people with hypertension. This study used Quasi-experimental one group pre-test and post-test design. The study population was elderly with hypertension taken by purposive sampling method, a total of 40 people with the criteria of being able to read, carry out activities independently, and live with family. The instrument used to measure variables is a questionnaire and data were analyzed using the Wilcoxon test. The average value obtained for knowledge of the hypertension diet increased by 14.78 and adherence to the hypertension diet also experienced an increase in the average value of 44.53. The results of the Wilcoxon test showed that there was an effect of the BASNEF model of health education on knowledge and adherence to the hypertension diet in elderly people with hypertension which was significant with p<0.05. The BASNEF method of health education can be an alternative to increasing knowledge and adherence to hypertension among elderly people in the community.
Impact of Perceived Vulnerability and Benefits on Adolescent Smoking Cessation Motivation Setyoadi; Aisyana, Lala; Sari, Efris Kartika; Ismail, Dina Dewi Sartika Lestari
Journal of Rural Community Nursing Practice Vol. 3 No. 1 (2025): March
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jrcnp.v3i1.404

Abstract

Background: Most smoking among adolescents aged 15-19 years is associated with a psychosocial crisis, as they are still searching for their identity. Factors such as perceived vulnerability and perceived benefits can lead adolescents to start smoking. Purpose: The purpose of this study was to determine the relationship between perceived vulnerability and perceived benefits and motivation for smoking cessation among adolescents. Methods: The research design uses an analytical observational design with a cross-sectional approach. The research sample consisted of adolescent smokers selected using a cluster random sampling technique, resulting in 136 participants. Data for variables were collected using the Perceived Vulnerability to Disease (PVD), Perceived Risks and Benefits Questionnaire (PRBQ), and Smoking Cessation Motivation Questionnaire (Q-MAT), which were modified by the researchers and tested for validity and reliability. The research data were analyzed using the Spearman Rank Test. Results: The results showed that 97.8% of participants had a positive perceived vulnerability, 97.1% had a positive perceived benefit, and 71.3% had a high motivation for smoking cessation. There was a significant relationship between perceived vulnerability and perceived benefits with motivation for smoking cessation, with a significant p-value of 0.000 and correlation values of +0.478 and +0.643. Conclusions: Adolescents' motivation to quit smoking is shaped by their awareness of health risks and the benefits of quitting, such as improved well-being and financial savings. Nursing-based interventions, including counseling, support groups, and school health campaigns, play a crucial role in reinforcing this motivation and ensuring long-term cessation.