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Dyan Kunthi Nugrahaeni, Dyan Kunthi
Stikes Jenderal A. Yani Cimahi
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ANALISIS PENYEBAB RESISTENSI OBAT ANTI TUBERKULOSIS Nugrahaeni, Dyan Kunthi
Jurnal Kesehatan Masyarakat Vol 11, No 1 (2015): JURNAL KESEHATAN MASYARAKAT (KEMAS) JULI 2015
Publisher : Jurusan Ilmu Kesehatan Masyarakat Fakultas Ilmu Keolahragaan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v11i1.3341

Abstract

Jumlah penderita TB Indonesia sekitar 5,8% total TB dunia dan menempati peringkat keempat dengan angka prevalensi 281/100.000 penduduk. Kendala program pemberantasan dan penanggulangan TB adalah Resistensi obat anti tuberkulosis, karena pengobatan lama, mahal, dan tingginya efek samping. Tujuan penelitian menganalisis penyebab resistensi OAT. Penelitian dilakukan pada tahun 2013 dengan rancangan penelitian menggunakan kasus kontrol. Sampel kasus penderita TB resisten dan sampel kontrol penderita TB yang sembuh masing-masing 26 orang. Data dari hasil pemeriksaan laboratorium dan catatan medik di RS Dr. HA. Rotinsulu Kota Bandung. Uji statistik dengan chi square dan besar risiko dari OR. Hasil penelitian didapatkan 80,8% kategori MDR-TB dan 19,2% XDR-TB. Penderita TB mengalami efek samping 42,3%, riwayat pengobatan tidak adekuat 96,2%, adanya kontak erat 30,8%, tempat pengobatan sebelumnya tidak menerapkan DOTS 15,4%. Penyebab resistensi OAT adalah riwayat pengobatan tidak adekuat (nilai p= 0,001; OR= 40,00, 95%CI: 4,66-343,14). Pencegahan resistensi OAT dengan penatalaksanaan TB komprehensif, menerapkan program DOTS agar pengobatan tidak terputus dan berkesinambungan. Number of case TB Indonesia approximately 5.8% total TB in world, was ranked fourth with prevalence rate 281/100,000 population. Anti-tuberculosis drug resistant become problem prevention and eradication TB programmes, because treatment for longer, expensive, and greater side effects. The purpose this study was analysis causes Anti-tuberculosis drug resistant. This research was conducted at 2013 with design using case control. Cases which TB patients drug resistance, control which patients were cured TB each one as 26 people. Data obtained from the results laboratory and medical records in  hospital Dr. HA. Rotinsulu Bandung. Statictic analyzed using chi-square test and risk factor from OR. Results showed 80.8% MDR-TB and 19.2% XDR-TB. TB patients who experience side effects 42.3%, inadequate treatment 96.2%, 30.8% close contact, not implementing DOTS 15.4%. The causes anti-tuberculosis drug resistance inadequate treatment (P value= 0.001; OR= 40.00, 95%CI: 4.66-343.14). Prevention of anti-tuberculosis drug resistance by comprehensive TB management, implementing DOTS program that uninterrupted and continuous treatment.
ANALISIS PENYEBAB RESISTENSI OBAT ANTI TUBERKULOSIS Nugrahaeni, Dyan Kunthi
KEMAS: Jurnal Kesehatan Masyarakat Vol 11, No 1 (2015)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v11i1.3341

Abstract

Jumlah penderita TB Indonesia sekitar 5,8% total TB dunia dan menempati peringkat keempat dengan angka prevalensi 281/100.000 penduduk. Kendala program pemberantasan dan penanggulangan TB adalah Resistensi obat anti tuberkulosis, karena pengobatan lama, mahal, dan tingginya efek samping. Tujuan penelitian menganalisis penyebab resistensi OAT. Penelitian dilakukan pada tahun 2013 dengan rancangan penelitian menggunakan kasus kontrol. Sampel kasus penderita TB resisten dan sampel kontrol penderita TB yang sembuh masing-masing 26 orang. Data dari hasil pemeriksaan laboratorium dan catatan medik di RS Dr. HA. Rotinsulu Kota Bandung. Uji statistik dengan chi square dan besar risiko dari OR. Hasil penelitian didapatkan 80,8% kategori MDR-TB dan 19,2% XDR-TB. Penderita TB mengalami efek samping 42,3%, riwayat pengobatan tidak adekuat 96,2%, adanya kontak erat 30,8%, tempat pengobatan sebelumnya tidak menerapkan DOTS 15,4%. Penyebab resistensi OAT adalah riwayat pengobatan tidak adekuat (nilai p= 0,001; OR= 40,00, 95%CI: 4,66-343,14). Pencegahan resistensi OAT dengan penatalaksanaan TB komprehensif, menerapkan program DOTS agar pengobatan tidak terputus dan berkesinambungan. Number of case TB Indonesia approximately 5.8% total TB in world, was ranked fourth with prevalence rate 281/100,000 population. Anti-tuberculosis drug resistant become problem prevention and eradication TB programmes, because treatment for longer, expensive, and greater side effects. The purpose this study was analysis causes Anti-tuberculosis drug resistant. This research was conducted at 2013 with design using case control. Cases which TB patients drug resistance, control which patients were cured TB each one as 26 people. Data obtained from the results laboratory and medical records in  hospital Dr. HA. Rotinsulu Bandung. Statictic analyzed using chi-square test and risk factor from OR. Results showed 80.8% MDR-TB and 19.2% XDR-TB. TB patients who experience side effects 42.3%, inadequate treatment 96.2%, 30.8% close contact, not implementing DOTS 15.4%. The causes anti-tuberculosis drug resistance inadequate treatment (P value= 0.001; OR= 40.00, 95%CI: 4.66-343.14). Prevention of anti-tuberculosis drug resistance by comprehensive TB management, implementing DOTS program that uninterrupted and continuous treatment.
The Relationship between Previous Tuberculosis Treatment and HIV Status with Multidrug-Resistant Tuberculosis Nugrahaeni, Dyan Kunthi; Zaqiya, Salma
KEMAS: Jurnal Kesehatan Masyarakat Vol 14, No 3 (2019)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v14i3.14087

Abstract

Multidrug-resistant tuberculosis (MDR-TB) is becoming major public health issues in the world. Among the causes are history of previous TB treatment and increased co-infection of TB-HIV (Human Immunodeficiency Virus). This study aimed to identify the relationship between history of previous TB treatment and HIV status with MDR-TB. This is a case control study. The sample case was patients with MDR-TB, while sample control was patient who have drug-sensitive TB. Secondary data was obtained from patient medical records and laboratory results at Rotinsulu Pulmonary Hospital Bandung. Data were analyzed using chi-square. Multiple logistic regression was used to identify the dominant factor that influence the occurrence of MDR-TB. This study showed that the history of previous TB treatment was statistically significant with MDR-TB (p value= 0.001; OR= 18.889; 95% CI= 4.093-87.172) and it is the dominant factor that influence MDR-TB (p value= 0.0001; OR= 56.84; 95% CI= 6.9- 468.87). HIV infection at control group (who contracted drug-sensitive TB) was 26.1% (p value= 0.022). This finding suggested that HIV testing should be performed to each TB and MDR-TB patients and increased collaboration TB-HIV program between the other health care facilities should ensue. Drug sensitivity testing should be conducted at the start of TB treatment for patients with previous TB treatment and TB-HIV co-infection.
Risk Assessment of Inhalation Exposure to the Use of Chemicals in the Mineral Processing Susanto, Arif; Mauliku, Novie Elvinawaty; Suhat, Suhat; Nugrahaeni, Dyan Kunthi; Budiana, Teguh Akbar
Jurnal Kesehatan Masyarakat Vol 19, No 2 (2023)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v19i2.42788

Abstract

Chemical exposure known as chemical hazards and toxic substances (CHTS), which occur through inhalation, ingestion, and skin contact, causes serious illness, irritation, corrosion, injury, and even death. The chemicals analyzed are limited to the reagents used in the mineral ore production process, in addition to dermal exposure. Data on hazard identification and exposure evaluation were collected. The utilization of CHTS will continue to increase in the coming years, thereby leading to health impacts on workers. Global data released by ILO showed a 270 million (62.8%) and 160 million (37.2%) rise in work accidents and illnesses, culminating in 430 million per year. Data on the number of workers who received benefits from the Work Accident Insurance program of the National Social Security Agency for Employment (known as BPJSTK), showed that 210,789 people (4,007 fatal) 221,740 people (3,410 fatal), and 234,370 people (6,552 fatal) experienced work-related accidents and illnesses in Indonesia. Therefore, this qualitative study aims to examine and analyze the health risks of mining workers exposed to CHTS through inhalation- using the observation method. The Chemical Health Risk Assessment (CHRA) method issued by the Malaysian Department of Safety and Health in 2018 was used to assess the inhalation exposure rate. The analyzed chemicals were limited to reagents used in production with data collected through the semi-quantitative method. The results showed that the inhalation exposure risk level is categorized as moderate and capable of causing health defects related to acute toxicity and specific target organ toxicity-single exposure (STOT-SE). Furthermore, 4 (four) out of 6 (six) reagents were identified as having significant inhalation exposure risk, hence, controls related to Occupational Health and Safety (OHS) in the mineral ore processing process must be increased.
Factor associated with anxiety disorder during covid-19 pandemic among college students Nugrahaeni, Dyan Kunthi; Mauliku, Novie Elvinawaty; Saputra, Aditiyana Eka; Lakhal, Bashir Mabrok
Jurnal Ilmiah Psikologi Terapan Vol. 11 No. 2 (2023): August
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/jipt.v11i2.22253

Abstract

Coronavirus Disease-2019 (COVID-19) is a novel illness not previously identified in humans. Its unprecedented emergence has resulted in many effects on individuals, including the onset of anxiety. Therefore, this study aimed to identify factors associated with an anxiety disorder during the COVID-19 pandemic among college students. Using a snowball sampling technique, a quantitative design was employed to select 453 participants. The instruments used were the 7-point Generalized Anxiety Disorder scale and the Multidimensional Scale of Perceived Social Support. Furthermore, data analysis was carried out using the Chi-Square test and Pearson’s correlation. Several factors related to anxiety disorder include gender (p=0.001), year of study (p=0.001), teaching delivery method (p=0.049), sources of information about COVID-19 (p=0.009), family member affected (p=0.009) and social support (p=0.001). The results showed that social support had a negative correlation with anxiety disorder, support from family (r=-0.33, p=0.001),friends (r=-0.31, p=0.001), and significant others (r=-0.23, p=0.001). Therefore, factors associated with anxiety disorder during the pandemic were gender, study year, teaching delivery method, sources of information, affected family members, and social support.
Hubungan asupan zat besi, vitamin C dan pengetahuan siswi terhadap kejadian Anemia pada remaja putri Budiana, Teguh Akbar; Nugrahaeni, Dyan Kunthi; Sari, Dewi Kartika; Ruhyandi, Ruhyandi; Mauliku, Novie Elvinawaty
Journal of Health Research Science Vol. 4 No. 02 (2024): Journal of Health Research Science
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Kesehatan Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34305/jhrs.v4i02.1395

Abstract

Latar Belakang: Anemia pada remaja masih menjadi permasalahan Kesehatan di Indonesia. Hasil screening tahun 2023 di Kota Cimahi menunjukan kejadian anemi pada siswi SMP/MTS 19.72% (ringan), 13.88% (sedang) dan 0.26% (berat). Tujuan untuk mengetahui hubungan asupan zat besi (Fe), vitamin C, dan pengetahuan siswi dengan kejadian anemia pada remaja putri.Metode: Studi analisis cross-sectional. Jumlah sampel sebanyak 61 siswi, yang dipilih melalui teknik proporsional sampling. Pengumpulan data primer didapatkan dari wawancara menggunakan kuesioner SQFFQ untuk mengidentifikasi asupan zat besi dan vitamin C siswi serta spektrofotometer untuk mengidentifikasi kadar hemoglobin, sedangkan data sekunder didapatkan dari absen nama dan kelas siswi perempuan. Analisis data menggunakan univariat dengan distribusi frekuensi dan bivariat dengan nutrisurvey dan chi-square.Hasil: 8 siswi (13,1%) mengalami anemia ringan, defisit berat zat besi (65,6%), defisit berat vitamin C (47,5%), serta (54,1%) memiliki pengetahuan cukup tentang anemia. Tidak terdapat hubungan yang signifikan antara asupan zat besi (p = 1,000), asupan vitamin C (p = 0,333), dan pengetahuan siswi (p = 0,476) dengan kejadian anemia.Kesimpulan: Tidak ada hubungan antara asupan zat besi, vitamin C dan pengetahuan siswi terhadap kejadian anemia.
Efektivitas Edukasi Keamanan Pangan Untuk Meningkatkan Praktik Pada UMKM Tahu di Wilayah Puskesmas Cibuntu Kota Bandung Kurniawan, Dwi; Riyanto, Agus; Budiana, Teguh Akbar; Nugrahaeni, Dyan Kunthi; Mauliku, Novie E.
Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal Vol. 15 No. 01 (2024): Jurnal Ilmu Kesehatan Bhakti Husada: Health Science Journal
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Kesehatan Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34305/jikbh.v15i01.1024

Abstract

Latar Belakang: Industri pangan di Indonesia berkembang sangat pesat, terdapat 70% UMKM bergerak di industri makanan. Seiring perkembangan tersebut, banyak ditemukan UMKM yang kurang terdidik dalam masalah keamanan pangan. Berdasarkan laporan tahunan Dinas Koperasi dan UMKM tahun 2021 di Jawa Barat terdapat 3 dari 622.225 UMKM yang memiliki sertifikasi HACCP, sedangkan Di kota Bandung terdapat satu UMKM yang sudah bersertifikat HACCP.Metode: Rancangan penelitian ini menggunakan desain Quasi Experimental dengan pendekatan Non-equivalent control group  prettest-posttest. Jumlah sampel 38 kelompok intervensi dan kontrol. Analisa statistik menggunakan uji dependen T-test, Independen T-test dan regresi logistic berganda.Hasil: Hasil penelitian menggunakan dependen T-test diperoleh p value pada kelompok intervensi (p 0,001) dan kelompok kontrol (p 0,044) yang artinya terdapat perbedaan praktik sebelum dan sesudah intervensi. Uji Independen T-Test diperoleh p value pada kelompok intervensi (p 0,001) dan kelompok kontrol (p 0,001) terdapat perbedaan praktik setelah intervensi. Hasil uji regresi logistik berganda bahwa jenis kelamin, usia dan tingkat pendidikan merupakan variable perancu.Kesimpulan: Edukasi keamanan pangan dapat direkomendasikan dalam peningkatan praktik pada UMKM tahu di Wilayah Puskesmas Cibuntu Kota Bandung.
FACTORS ASSOCIATED WITH TUBERCULOSIS-DIABETES MELLITUS COMORBIDITY: Faktor-faktor yang Berhubungan dengan Komorbiditas Tuberkulosis-Diabetes Mellitus Nugrahaeni, Dyan Kunthi; Kusumasari, Ika; Budiana, Teguh Akbar; Mauliku, Novie Elvinawaty
Jurnal Berkala Epidemiologi Vol. 13 No. 1 (2025): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V13I12025.75-84

Abstract

Background: The double burden disease refers to the increase of communicable and non-communicable disease, such as comorbidity tuberculosis (TB) with diabetes mellitus (DM). If not treated properly and managed, tuberculosis can lead to comorbidity with diabetes mellitus. Purpose: This research aims to determine factors associated with tuberculosis-diabetes mellitus comorbidity. Methods: Research design used case-control study, sample cases are TB patients with DM as many as 15 people, while sample control is TB patient without DM as many as 30 people. Independent variables include age, education, occupation, TB severity, body mass index, and quality of life, while the dependent variable is comorbidity TB-DM. The instrument used the World Health Organization’s Quality of Life Brief Version (WHOQOL-BREF). Data analysis was performed utilizing the Chi-Square test and Independent T-test. Results: This study’s findings indicated that the variable age (p= 0.011; OR= 6; 95% CI= 1.39-25.85), education (p=0.03; OR= 4.12; 95% CI= 1.06-16.03), TB severity (p= 0.02; OR= 4.57; 95% CI= 1.18-17.67), and quality of life domains were significantly related to TB-DM with comorbidity: physical (p=0.00; OR=42.25; 95%CI=6.82-261.61), psychological (p=0.03; OR=4; 95% CI=1.07-14.89) and environmental domain (p=0.01; OR=10.54; 95% CI=1.06-105.03). Conclusion: Factors influencing comorbidity between TB-DM include age, education level, TB severity and quality of life. Enhancing immunity in TB patients is essential to reduce the severity of TB and comorbidity of TB-DM, with recommendations for support from family, parents, children, and friends to improve the quality of life for those with TB-DM.
Evaluasi Implementasi Program Pengendalian Kebisingan terhadap Penurunan Pendengaran pada Pekerja di PT “XYZ” Dwi Enggar Widi Saptana; Mauliku, Novie Elvinawaty; Suhat, Suhat; Nugrahaeni, Dyan Kunthi
INSOLOGI: Jurnal Sains dan Teknologi Vol. 4 No. 2 (2025): April 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v4i2.5090

Abstract

Noise is one of the physical hazard factors in the work environment. Workers who are exposed to noise exceeding the Threshold Value above 85 db can cause permanent hearing loss. This can be overcome by optimizing the efforts of elimination, substitution, isolation, administrative control, and the use of PPE. Therefore, it is necessary to apply the Hearing Conservation Program. The purpose is to evaluate the implementation of the noise control program on hearing loss in workers at PT “XYZ”. The research design used a qualitative with an evaluative approach. The informants who informan were management, HSE, electrical technician, mechanic topside, and marine pumpman. Data collection techniques used in-depth interviews, observation, and document review, with instruments in the form of interview sheets, observation sheets, and checklist sheets. Data analysis was done by triangulation and data reduction. The results showed the company has a commitment and policy in an effort to reduce noise levels, but it hasn’t been maximized because elimination and substitution efforts cannot be applied, and it was found that there are still employees who are not fully compliant in using PPE in the workplace. Based on the results, it is concluded that the evaluation of the implementation of the noise control program on hearing loss in workers at PT XYZ has been running well. PT. XYZ demonstrates strong commitment to noise control, but faces challenges in implementation, including suboptimal noise control measures and incomplete PPE compliance.
Video Media Health Education on Knowledge, Attitudes, and Personal Hygiene Practices During Menstruation Ulfah, Nadila Dewi; Nugrahaeni, Dyan Kunthi; Mauliku, Novie Elvinawaty
Jurnal Keperawatan Profesional (KEPO) Vol. 6 No. 1 (2025): Volume 6 Nomor 1 Mei 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/kepo.v6i1.1484

Abstract

Poor personal hygiene during menstruation had a significant impact on morbidity and complications. Lack of menstrual hygiene awareness was influenced by knowledge and attitudes, as well as external factors such as parental, teacher, peer support, and exposure to information. This study aimed to determine the effect of video-based health education on knowledge, attitudes, and personal hygiene practices during menstruation. The study employed an experimental pre-posttest design. The study population consisted of 98 female students. The sample was divided into two groups: a control group and a treatment group. The results showed differences in the mean scores for knowledge (p-value=0,021), attitudes (p-value=0,000), and practices (p-value=0,000). Parental support (p-value=0,000), teacher support (p-value=0,000), and peer support (p-value=0,000) were identified as confounding factors affecting menstrual hygiene. There was a significant difference in the mean scores of knowledge, attitudes, and practices after the video education intervention. It is recommended that adolescent girls develop clean and healthy living habits by consistently maintaining genital hygiene, both during menstruation and outside of it.
Co-Authors Agus Riyanto Arif Susanto Ayu Laili Rahmiyati Budiman Budiman Dewi Kartika Sari Dwi Enggar Widi Saptana Dwi Kurniawan, Dwi Ika Kusumasari, Ika Kusniawaty, Ani Lakhal, Bashir Mabrok Mauliku, Novie E. Mauliku, Novie Elvinawaty Oktavia, Yenni Ruhyandi, Ruhyandi Saputra, Aditiyana Eka Suhat Suhat Sumardi, Dini Rahayu Teguh Akbar Budiana Ulfah, Nadila Dewi Zaqiya, Salma