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All Journal Berkala Kedokteran Universa Medicina Jurnal Ilmu Kefarmasian Indonesia Prosiding Seminar Nasional Program Pengabdian Masyarakat JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Kedokteran Hewan
Dwi Nur Ahsani
Departemen Histologi Fakultas Kedokteran Universitas Islam Indonesia.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary

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EFFECT OF CIPLUKAN STEMS AND LEAVES EXTRACT ADMINISTRATION (Physalis angulata L.) ON THE DEGREE OF hepatic lobes INFLAMMATION IN DYSLIPIDEMIA INDUCED WISTAR RATS Safira, Nazala; Pamungkas, Katon; Utami, Rizki fajar; Ahsani, Dwi Nur; Pramaningtyas, Miranti Dewi
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.32339

Abstract

The aim of this study was to determine the effect of stems and leaves ciplukan extract on the degree of liver lobe inflammation in dyslipidemia-induced wistar rats. This research was an experimental study with a post-test only design. A total of 24 Wistar rats were allotted into 4 groups with 6 rats per group. Hepatic organs were then histologically stained with Hematoxylin-Eosin stain. Inflammation reading was done by looking for inflammatory foci in the preparation. The result was then analyzed using Kruskal-Wallis test. The results showed that groups I and II had one severe inflammation. Group III had two severe degrees of inflammation. Group IV had no severe inflammation. The analysis revealed that there was no significant difference in the degree of inflammation between groups (P= 0.964). Administration of ciplukan stem and leaf extract did not affect the degree of liver lobe inflammation in Wistar rats induced by dyslipidemia.
Co-Authors Alissa Anna Safira Dodi Faras Ilmiawan Sutomo Harmi, Khoviya Yuwina Selinada Hilmi Ardian Sudiarto Ika Fidianingsih Khotibuddin, Muhammad Maruni Wiwin Diarti Miranti Dewi Pramaningtyas Pamungkas, Katon RIZKI FAJAR UTAMI Safira, Nazala Sherly Usman Yuantari, Rahma