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All Journal Majalah Kedokteran Bandung Althea Medical Journal Global Medical and Health Communication ODONTO Dental Journal MNJ (Malang Neurology Journal) PENELITIAN DAN KARYA ILMIAH Jurnal Ilmu Bedah Indonesia JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Jurnal Penelitian dan Karya Ilmiah Lembaga Penelitian Universitas Trisakti Odonto dental journal
Harry Galuh Nugraha
Department Of Radiology Faculty Of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung Indonesia
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THE ROLE OF MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS AND STAGING OF ORAL SQUAMOUS CELL CARCINOMA: CASE REPORTS Rahmi Harmiyati; Irna Sufiawati; Harry Galuh Nugraha
Odonto : Dental Journal Vol 9: Special Issue 1. April 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (570.269 KB) | DOI: 10.30659/odj.9.0.24-32

Abstract

CLINICAL CHARACTERISTICS OF LACUNAR ISCHEMIC STROKE PATIENTS Anindyta Murfia Khairunnisa; Lisda Amalia; Eppy Buchori Aristiady; Harry Galuh Nugraha; Asep Nugraha Hermawan
MNJ (Malang Neurology Journal) Vol. 9 No. 2 (2023): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.02.9

Abstract

Background: Stroke is the leading causes of death and disability in the world. Ischemic stroke covered 85% of stroke types. Based on the subtypes of ischemic stroke, lacunar ischemic stroke encompassed 20% of them. Knowing the characteristics help physicians to diagnose patients clinically and offer management to treat risk factors. Objective: This study aimed to know the characteristics of lacunar ischemic stroke based on patients risk factors, ischemic location on CT-scan, clinical syndrome, and NIHSS score. Methods: Using retrospective analytical study with cross sectional approach, medical record data from 2019-2022 were collected from RSUP DR. Hasan Sadikin Bandung. Results: From 60 patients, 35% (21) are 55-64 years old. Both sexes are equally distributed. 50 patients (83.3%) have multiple risk factors. Out of 60 patients, 57 (95%) have hypertension, 8 (13.3%) have diabetes mellitus, 44 (73.3%) have dyslipidemia, 6 (10%) have hyperuricemia, and 14 (23.3%) smoke. On admission, out of 60 patients, 34 (56.7%) have mild stroke, 23 (38.3%) have moderate stroke, 2 (3.3%) have moderate to severe stroke, and 1 (1.7%) has severe stroke. 44 (73.3%) out of 60 patients have pure motor hemiparesis. 41 (68.3%) out of 60 patients have basal ganglia ischemic. Conclusion: Lacunar ischemic stroke patients were equally distributed in sex with peak incidence occur between 55-64 years old. Most patients have multiple risk factors, basal ganglia lesion, pure motor hemiparesis, and history of hypertension, dyslipidemia, and smoking. On admission, most patients have mild stroke, followed by moderate stroke.
STUDI PENDAHULUAN PENGGUNAAN VOLUME OF INTEREST (VOI) DALAM MENGANALISIS BIODISTRIBUSI SENYAWA PENGONTRAS GD-DTPA-FOLAT DIBANDINGKAN DENGAN GD-DTPA PADA HEPAR DAN GINJAL TIKUS MENGGUNAKAN MRI Rahmansyah, Mulia; Yusuf, Iyus Maolana; Nugraha, Harry Galuh; Soetikno, Ristaniah D.
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 6, Nomor 1, Januari 2021
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v6i1.8624

Abstract

Magnetic Resonance Imaging (MRI) merupakan modalitas pencitraan diagnostik yang sebagian besar menggunakan senyawa pengontras. Konsentrasi senyawa pengontras dapat diukur secara tidak langsung dari peningkatan instensitas sinyal yang merupakan bagian dari analisis tekstural ditampilkan dengan Region of Interest (ROI) ataupun Volume of Interest (VOI). Dua organ eliminasi dalam biodistribusi obat dalam tubuh yaitu hepar dan ginjal. VOI merupakan penilaian yang mencakup kuantifikasi tekstur seluruh jaringan, sehingga VOI dapat menilai biodistribusi pada hepar dan ginjal. Tujuan dari penelitian ini yaitu untuk menganalisis VOI senyawa pengontras Gd-DTPA-Folat dan Gd-DTPA dan membandingkannya dengan ROI dan target to background ratio. Studi pendahuluan yang merupakan penelitian observasional analitik menggunakan data prospektif. Analisis statistik menggunakan tes Mann-Whitney untuk membandingkan perbedaan intensitas sinyal senyawa pengontras Gd-DTPA-Folat dan Gd-DTPA pada konsentrasi 112 mg/0,5 ml dengan waktu pindai yang berbeda. Sampel dibagi menjadi 2 kelompok yang masing-masing terdiri dari 3 ekor tikus putih. Variabel independen adalah jenis kontras dan waktu pindai, variabel dependen adalah nilai ROI, target to background ratio, dan VOI. Variabel perancu dipengaruhi oleh perbedaan tempat dan ukuran. Bias dikurangi dengan pengukuran minimal 3 kali dengan ukuran 20 mm2. VOI digunakan sebagai modifikasi efek. Nilai rerata VOI Gd-DTPA-Folat dan Gd-DTPA memiliki nilai yang hampir sama pada hepar dan ginjal pada waktu yang berbeda serta menunjukkan waktu yang optimal pada 1 jam pertama. VOI memiliki keunggulan dalam menilai biodistribusi senyawa pengontras pada organ hepar dan ginjal dibandingkan dengan ROI dan target to background ratio.
Co-Authors Anindyta Murfia Khairunnisa Arie Hendarin, Arie Asep Nugraha Hermawan Dede Marina Eppy Buchori Aristiady Irna Sufiawati Iyus Maolana Yusuf Lanny Noor Diyanti Leni Santiana Lisda Amalia Maman Wastaman Rodjak Mulia Rahmansyah Rahmansyah, Mulia Rahmi Harmiyati Reno Rudiman Reno Rudiman Rista D. Soetikno, Rista D. Ristaniah D. Soetikno Ristaniah D. Soetikno Rizki Diposarosa Rodjak, Maman Wastaman Silmina Kusmaheidi Silmina Kusmaheidi, Silmina Singarimbun, Wilner Wilner Singarimbun Yusuf, Iyus Maolana