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All Journal Abdi Dosen : Jurnal Pengabdian Pada Masyarakat Prosiding University Research Colloquium Journal of Innovative and Creativity IJF (Indonesia Jurnal Farmasi) Jurnal Abdimas Indonesia Journal of Pharmascience
Eko Retnowati
Universitas Muhammadiyah Kudus
Religion Humanities Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Lumbricus Rubellus Earthworm Extract Hydrogel for Treatment of Diabetic Ulcer Wounds Diana Tri Lestari; Muhamad Jauhar; Eko Retnowati
Journal of Pharmascience Vol. 13 No. 1 (2026): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v13i1.22880

Abstract

A diabetic ulcer is a complication that requires serious treatment because it is the highest cause of amputation. This condition has an impact on the morbidity, mortality, and socioeconomics of people with diabetes. Therefore, accuracy is needed in managing diabetic ulcers, one of which is natural ingredients that have potential as topical ulcer medicines, namely the Lumbricus rubellus earthworm. This study aims to find out the most effective formula for the treatment of diabetic ulcer wounds. The formula for this drug candidate is made using the hydrogel preparation formulation using an HPMC 940 base with variations in the active ingredient of lumbricus worm extract of 20%, 50%, and 80% to obtain the desired hydrogel preparation. The candidate drug will be tested, namely physical tests including organoleptic tests, homogeneity tests, pH tests, viscosity tests, spreadability tests, and adhesive tests. After that in vivo trial using Wistar rat experiments. The results of the organoleptic test showed that the three formulas were in gel form with a distinctive extract odor, but the three preparations showed different colors, namely brownish yellow, dark brown, and blackish brown. The three formulations appear homogeneous, having a pH between 4.36 and 4.44 and a viscosity between 5,376 cp and 5,894 cp. The spreading power in formulas 2 and 3 is good, and formula 2 has good adhesion. The results of this study demonstrate that the group treated with 50% L. rubellus topical extract experienced the most significant and rapid wound healing among all intervention groups. L. rubellus extract can be used as a topical gel preparation for wound care, with the best formulation at a concentration of 50%.
EDUCATION ON INITIAL HANDLING OF RESPIRATORY SYNCYTIAL VIRUS INFECTION IN MOTHERS OF KRAPYAK VILLAGE, TAHUNAN, JEPARA Anisah Nurussyifa; Eko Retnowati; Ulviani Yulia Husna
Abdi Dosen : Jurnal Pengabdian Pada Masyarakat Vol. 10 No. 2 (2026): JUNI
Publisher : LPPM Univ. Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/abdidos.v10i2.3451

Abstract

Respiratory Syncytial Virus (RSV) is one of the main causes of lower respiratory tract infections in children under five years old. Limited public knowledge regarding transmission, prevention, and early management of RSV increases the risk of severe complications, especially in rural areas such as Krapyak Village. This community service activity aimed to improve mothers’ knowledge regarding the early management of RSV infection through a health education program. The activity used a pre-experimental one-group pre-test post-test design involving 53 mothers with toddlers at Posyandu Mawar 6, Krapyak Village. The intervention included health education sessions, animated videos, interactive discussions, and leaflet distribution. Data were collected using a validated questionnaire and analyzed using the Wilcoxon signed-ranks test and N-Gain score. The results showed a significant increase in respondents’ knowledge after the intervention, with most participants achieving a good level of knowledge and an average N-Gain score in the moderate category. The program was effective in improving mothers’ understanding of early RSV management and is expected to support better preventive practices among toddlers in Krapyak Village.
Co-Authors Adisti Maulina Firdaus Anisah Nurussyifa Bintari Tri Sukoharjanti Devi Ayu Alami Devi Renha Lestari Diana Tri Lestari Endang Setyowati Fahrudin Arif Hardiyani Presticasari Latifah Dikdayani Latifah Dikdayani Muhamad Jauhar Munawaroh Munawaroh N Nirmala Nisa Indah Setyani Noor Elvina Lailatul Fitria Nur Farida Ulfa Nurul Huda Septiana Dwi Astuti Sitta Hasanatin Sholihah Sitta Hasanatin Solikah Teguh Asrroyo Ulviani Yulia Husna Yayuk Mundriyastutik Yulis Trinovita