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All Journal Jurnal Penelitian Sekolah Tinggi Ilmu Kesehatan Nahdlatul Ulama Tuban Proceeding Mulawarman International Conference on Tropical Public Health
Leny Eka Tyas Wahyuni
Mulawarman University
Health Professions Nursing Public Health Veterinary

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EFEKTIFITAS EKSTRAK ETANOL DAUN SIRSAK (Annona Muricata L.) TERHADAP KADAR GLUKOSA DARAH TIKUS PUTIH (Rattus norvegicus) YANG DIINDUKSI ALOKSAN Ainun Najib; Leny Eka Tyas Wahyuni; Adieba Warda Hayya; Alfian Abdul Rajab
Jurnal Penelitian Vol 4, No 2 (2022): JURNAL PENELITIAN
Publisher : Institut Ilmu Kesehatan Nahdlatul Ulama Tuban

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47710/jp.v4i2.181

Abstract

Soursop leaves (Annona muricata L.) contain flavonoid compounds. Flavonoid compounds act as diabetes drugs. This study aimed to determine the effect of soursop leaf ethanol extract on alloxan-induced hypoglycemia in white male rats. In this study, four treatment groups were used, namely. negative control received no treatment, positive control received treatment with metformin 9 mg, the first treatment 7.2 mg and the last group was treated with a second dose of 14.4 mg. Rats were satisfied first before being treated, then measured blood sugar levels were. Rats were induced with alloxan intraperitoneally (IP), then observed the development of their blood sugar levels for three days, and their blood sugar levels were checked once a day. For seven days, then given ethanol extract of Soursop leaves daily for five days. The results showed that soursop leaf ethanol extract could reduce blood glucose on days H4-H8, which decreased by 6.67 mg / mL in the treatment group 1 sample and 5.66 mg / mL in the treatment sample.2. The test results with the Kruskal-Wallis test at the level of 0.05 showed that there was no significant difference between the use of soursop leaf ethanol extract and metformin against blood sugar reduction.
Effect of Arrowroot Cookies with Porang (Amorphophallus Oncophyllus) Glucomannan Addition on Atherogenic Index of Plasma In Type 2 Diabetes Erri Larene Safika; Lily Arsanty Lestari; Vita Yanti Anggraeni; Eni Harmayani; Leny Eka Tyas Wahyuni
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Abstract

Background : Type 2 diabetes (T2D) patients are at risk of developing cardiovascular diseases (CVD). Arrowroot cookies with porang glucomannan which are rich in dietary fiber may be able to reduce CVD risk in T2D patients. Objective : This study aimed to evaluate the effect of cookies consumption for 8 weeks on the atherogenic index of plasma (AIP) of T2D patients. Research Methods/ Implementation Methods : As many as 24 T2D subjects were recruited from primary health centers in Yogyakarta. The control group (n=12) was given nutrition education, and the intervention group (n=12) was given nutrition education and 5 pieces of cookies (65 grams) as daily snacks for 8 weeks. AIP [log(TG/HDL-C)], anthropometry, and food intake were measured before (week 0) and after (weeks 8) the study. Results : There was a decrease in AIP in the intervention group from 0.189 to 0.164 (medium-risk of CVD), although it wasn’t significant (p>0.05). On the contrary, the AIP level in the control group increased from 0.075 (low-risk of CVD) to 0.111 (medium-risk of CVD). The AIP changes between groups were not significantly different (p>0.05). There were no changes in anthropometry measures in both groups after the study (p>0.05). We found an increase in dietary fiber intake in both groups (p<0.05), however, it was not significantly different between groups (p>0.05). Conclusion/Lesson Learned : Consumption of 65g arrowroot cookies with porang glucomannan addition for 8 weeks did not significantly affect the AIP in T2D patients. However, it could maintain the AIP level in the intervention group in the medium-risk category and may serve as safe snacks for T2D patients.
Comparative study of vitamin c content in rome Beauty apples (malus sylvestris mill) with several Processing methods Leny Eka Tyas Wahyuni; Leily Amalia Furkon; Erri Larene Safika; Nur Rezky Khairun Nisaa
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Abstract

Background : Apples are known to contain antioxidants and vitamin C, which play important roles in protecting the body from oxidative stress and degenerative diseases. However, vitamin C is sensitive to heat, light, and oxygen, which can lead to degradation during processing. Objective : This study aimed to compare the vitamin C content of Rome Beauty apple (Malus sylvestris Mill) in various processed forms commonly consumed by the public, including fresh apple, apple juice, cider, dodol, and apple chips. Research Methods/ Implementation Methods : The research was conducted using a titrimetric method with 2,6-dichlorophenol-indophenol dye to determine vitamin C content. Five samples were analyzed in duplicate. The data were statistically tested using the Kruskal–Wallis and Mann–Whitney tests to evaluate differences among samples. Results : The vitamin C content ranged from 2.85 to 12.36 mg/100 g. The highest content was found in fresh apples (12.36 mg/100 g), followed by apple juice (6.41 mg/100 g), apple extract (5.23 mg/100 g), apple dodol (2.85 mg/100 g), and apple chips (2.85 mg/100 g). Statistical analysis showed significant differences (p < 0.05) among the samples, particularly between fresh or juiced apples and processed forms such as dodol and chips. Conclusion/Lesson Learned : Processing significantly reduces the vitamin C content of Rome Beauty apples. Heat treatment, oxidation, and exposure to air during processing are the major factors contributing to vitamin C loss. Therefore, consuming fresh apples provides the greatest nutritional benefit in terms of vitamin C intake.
EFFECT OF ARROWROOT cOOKIES WITH PORANG (Amorphophallus oncophyllus) GLUCOMANNAN ADDITION ON ATHEROGENIC INDEX OF PLASMA IN TYPE 2 DIABETes Erri Larene Safika; Vita Yanti Anggraeni; Eni Harmayani; Lily Arsanti Lestari; Leny Eka Tyas Wahyuni
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background and aims: Type 2 diabetes (T2D) patients are at risk of developing cardiovascular diseases (CVD). Arrowroot cookies with porang glucomannan which are rich in dietary fiber may be able to reduce CVD risk in T2D patients. This study aimed to evaluate the effect of cookies consumption for 8 weeks on the atherogenic index of plasma (AIP) of T2D patients. Material and method: As many as 24 T2D subjects were recruited from primary health centers in Yogyakarta. The control group (n=12) was given nutrition education, and the intervention group (n=12) was given nutrition education and 5 pieces of cookies (65 grams) as snacks for 8 weeks. AIP [log(TG/HDL-C)], anthropometry, and food intake were measured before (week 0) and after (weeks 8) the study. Results: There was a decrease in AIP in the intervention group from 0.189 to 0.164 (medium-risk of CVD), although it wasn’t significant (p>0.05). On the contrary, the AIP level in the control group increased from 0.075 (low-risk of CVD) to 0.111 (medium-risk of CVD). The AIP changes between groups were not significantly different (p>0.05). There were no changes in anthropometry measures in both groups after the study (p>0.05). We found an increase in dietary fiber intake in both groups (p<0.05), however, it was not significantly different between groups (p>0.05). Conclusions: Consumption of 65g arrowroot cookies with porang glucomannan addition for 8 weeks did not significantly affect the AIP in T2D patients. However, it could maintain the AIP level in the intervention group in the medium-risk category.
Co-Authors Adieba Warda Hayya Ainun Najib Alfian Abdul Rajab Eni Harmayani Erri Larene Safika Leily Amalia Furkon Lily Arsanti Lestari Lily Arsanty Lestari Nur Rezky Khairun Nisaa Vita Yanti Anggraeni