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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Novem Medika Farmasi Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Arfiani Arifin
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Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

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FORMULASI DAN UJI STABILITAS FISIK GEL ANTIJERAWAT EKSTRAK ETANOL DAUN SURUHAN (Peperomia pellucida L.) Arfiani Arifin; Intan Intan; Nur Ida
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.908

Abstract

Suruhan leaves (Peperomia pellucida L.) are known to be rich in secondary metabolites including alkaloids, flavonoids, saponins, tannins and triterpenoid compounds that have potential as anti-acne so that they can be applied as active ingredients in gel preparations. The purpose of this study was to determine the best base for the formulation of an anti-acne gel preparation of suruhan leaf extract that was physically stable. The research method includes the extraction of suruhan leaves by maceration using 96% ethanol. The gel formulation was designed with variations of carbopol base, HPMC, and Na CMC with a concentration of 2%. Physical stability tests include organoleptic, homogeneity, pH, dispersion, viscosity and adhesion which were carried out before and after accelerated storage using a climatic chamber. The results of this study showed that the gel preparation of the ethanol extract of suruhan leaves using carbopol and HPMC bases produced a physically stable gel based on the results of organoleptic tests, homogeneity, pH, dispersibility, adhesion and viscosity, before and after accelerated storage.
Co-Authors Astriani, Andi Dian Intan Intan Mawarni, Razifah Suci Muhammad Iqbal Nada, Salsabila Nur Ida