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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Arfiani Arifin
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Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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FORMULASI DAN UJI STABILITAS FISIK GEL ANTIJERAWAT EKSTRAK ETANOL DAUN SURUHAN (Peperomia pellucida L.) Arfiani Arifin; Intan Intan; Nur Ida
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.908

Abstract

Suruhan leaves (Peperomia pellucida L.) are known to be rich in secondary metabolites including alkaloids, flavonoids, saponins, tannins and triterpenoid compounds that have potential as anti-acne so that they can be applied as active ingredients in gel preparations. The purpose of this study was to determine the best base for the formulation of an anti-acne gel preparation of suruhan leaf extract that was physically stable. The research method includes the extraction of suruhan leaves by maceration using 96% ethanol. The gel formulation was designed with variations of carbopol base, HPMC, and Na CMC with a concentration of 2%. Physical stability tests include organoleptic, homogeneity, pH, dispersion, viscosity and adhesion which were carried out before and after accelerated storage using a climatic chamber. The results of this study showed that the gel preparation of the ethanol extract of suruhan leaves using carbopol and HPMC bases produced a physically stable gel based on the results of organoleptic tests, homogeneity, pH, dispersibility, adhesion and viscosity, before and after accelerated storage.
FORMULASI DAN UJI KARAKTERISTIK FISIK SEDIAAN PATCH EKSTRAK ETANOL DAUN KUMIS KUCING (Orthosiphon stamineus) Arfiani Arifin; Muhammad Iqbal
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i2.280

Abstract

Various forms of medicine can provide options for using drugs to the public such as patch. The research purpose was to determine variation concentration of Polyvinylpirolidone (PVP) and Ethyl cellulose (EC) as polymer patch which obtain the best physical characteristics of the Orthosiphon stamineus leaves ethanol extract patch. The ethanol extract of Orthosiphon stamineus leaves was obtained through maceration method using 70% ethanol solvent. The extract was formulated in the form of patch using the solvent casting method. The result showed that the best physical characteristics patch formulation was the F3 formula (250 mg of EC and 25 mg of PVP) with organoleptic test (a brownish green color, square shape and characteristic odor), patch humidity ( 3,64%), the average weight uniformity test (0.567 gram ± 0.01) and the patch thickness test (0.375 mm ± 0.02).
Co-Authors ekawati Intan Intan Muhammad Iqbal Nur Ida