Pradita Fiqlyanur Isna Primadana
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Perbedaan Tingkat Pengetahuan Siswa SMA Darul Kholil Burneh Bangkalan tentang Obat Generik Antara Sebelum dan Setelah Edukasi Abdul Hakim; Arief Suryadinata; Pradita Fiqlyanur Isna Primadana
Jurnal Pharmascience Vol 9, No 2 (2022): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i2.13517

Abstract

Obat generik merupakan program Pemerintah Indonesia untuk meningkatkan kualitas kesehatan di Indonesia. Namun, masih banyak yang belum mengetahui tentang obat generik, sehingga perlu adanya pemberian edukasi untuk meningkatkan pengetahuan tentang obat generik. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan tingkat pengetahuan siswa SMA Darul Kholil Burneh Bangkalan tentang obat generik antara sebelum dan sesudah edukasi. Penelitian ini menggunakan metode eksperimental one-group pretest postest design, pengambilan sampel dilakukan dengan teknik stratafied random sampling. Sampel yang digunakan pada penelitian ini sejumlah 72 responden. Penelitian ini dilakukan pada bulan Desember 2021-Januari 2022. Hasil pada penelitian ini diperoleh yaitu saat pretest terdapat 14% dengan tingkat pengetahuan baik, 65% dengan tingkat pengetahuan cukup dan 21% dengan tingkat pengetahuan kurang baik. Sedangkan saat postest diperoleh hasil 100% responden tergolong tingkat pengetahuan baik. Berdasarkan hasil penelitian ini terdapat perbedaan tingkat pengetahuan antara sebelum dan setelah edukasi, hal tersebut dibuktikan dengan hasil uji Wilcoxon yang diperoleh nilai Asymp.Sig (2-Tailed) 0,0001. Kata Kunci: Obat Generik, Tingkat Pengetahuan, Edukasi, One Group Pre-Post TestGeneric drugs are a program of the Indonesian government to improve the quality of health in Indonesia. However, there are still many who do not know about generic drugs, so there needs to be education to increase knowledge about generic drugs. The purpose of this study was to find out the difference in high school student Darul Kholil Burneh Bangkalan's knowledge level about generic drugs between before and after education. This study uses an experimental method of one-group pretest postest design, sampling is done with stratafied random sampling techniques. The sample used in this study was 72 respondents. The study was conducted in December 2021-January 2022.  The results in this study were obtained when the pretest there was 14% with a good level of knowledge, 65% with a sufficient level of knowledge and 21% with a level of knowledge less good. While when postest obtained the results of 100% of respondents classified as a good level of knowledge. Based on the results of this study there is a difference in the level of knowledge between before and after education, it is evidenced by the results of the Wilcoxon test obtained asymp.Sig (2-Tailed) value of 0.0001.
Application of the Simplex Lattice Design Methode to Determine the Optimal Formula Nanoemulsion with Virgin Coconut Oil and Palm Oil Pradita Fiqlyanur Isna Primadana; Tristiana Erawati; Noorma Rosita; Hamdan, Siti Hartini
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 3 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i32024.395-401

Abstract

Background: The success of nanoemulsion preparation is characterized by characteristics such as small droplet size, polydispersity index (PDI), and % transmittance, which are close to 100%. One of these factors is the type of oil component used. The Simplex Lattice Design (SLD) method can be used to determine the ratio of oil combinations to obtain an optimal nanoemulsion formula. Objective: The application of the Simplex Lattice Design (SLD) method can help researchers speed up the acquisition of optimal formulas without trial and error so that nanoemulsion formulas that meet specifications can be obtained. Methods: This research uses the Simplex Lattice Design (SLD) method with Design of Expert Version 13 software, with an upper limit value for oil (VCO and Palm Oil) of 2.66% and a lower limit value for oil (VCO and Palm Oil) of 0, which then The results of several formulas come out and characterization testing is carried out to get the best formula from the recommendations produced by the software. Results: The results of the Simplex Lattice Design (SLD) showed that oil affected the droplet size and PDI (p <0.05). Six optimal formulas were obtained, and after testing in the laboratory, there was no significant difference between the results of the SLD program and those of the laboratory (Sig. <0.05). Conclusion: This study shows that the Simplex Lattice Design (SLD) method is very effective.