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ENVIRONMENTAL ENHANCEMENT INCREASED SPATIAL MEMORY BUT NO SINGNIFICANT EFFECT ON ANXIETY IN RAT WITH PROPYLTHIOURACIL INDUCTION Noor, Zulkhah; Puspitasari, Dewi Alfika; Adiyani, Oktavia
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 10 No. 2 (2023)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2023.1032

Abstract

This study aims to determine the effect of environmental enrichment on spatial memory and anxiety in Propylthiouracil (PTU)-induced thyroid disorder rats. The design of this study was an experimental post test and controlled group design to analyze differences in spatial memory in rats at the end of the study. The subjects in this study were normal rat pups and Rat with PTU induction. Subjects were divided into 4 groups namely, the control group, the normal group with environmental enrichment, the rat group with PTU induction, and the rat group with PTU induction with environmental enrichment. Each group consisted of 8 rats. At the time the rats were born, the rats were given 0.025% PTU which was mixed in their drink and given to the mother until the rats were born until they were 4 weeks old. Environmental enrichment was carried out for 6 weeks. The spatial memory test in Rat was carried out when the pups were 60 days old. Data analysis used One Way Annova, Kruskal Wallis, Post Hoc Test and Mann-Whitney Test. Enrichment of the environment increased the learning latency time of normal rats by 27.8 ± 1.509 seconds to 9.9 ± 4.434 seconds with memory retention increasing by 6.85% (p <0.05). Environmental enrichment in PTU-induced rats accelerated from 84.5 ± 8.70 to 77 ± 1.383 with memory retention increasing by 7.06% (p <0.05). Environmental enrichment did not significantly affect the behavior and anxiety of normal rats or PTU induced (p>0.05). Environmental enrichment to normal rats and impaired thyroid function can increase spatial memory but has no effect on reducing anxiety.
Sleep Quality and Junk Food Consumption in Relation to Body Mass Index Among Medical Students at Universitas Muhammadiyah Yogyakarta Pramono, Muhammad; Noor, Zulkhah
Health & Medical Sciences Vol. 3 No. 2 (2026): February
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i2.584

Abstract

This study sought to investigate the correlation between sleep quality and the frequency of junk food consumption with body mass index (BMI) among medical students at Universitas Muhammadiyah Yogyakarta (UMY). A quantitative cross-sectional study was executed via purposive sampling of medical students from the 2020–2022 cohorts. An online questionnaire was used to collect data on the respondents' characteristics, their self-reported weight and height (to calculate BMI), their sleep quality (using the Pittsburgh Sleep Quality Index), and how often they ate junk food (using a food frequency questionnaire). Separate correlation studies were conducted for men and women. There was no significant link between sleep quality and BMI in either males (p=0.502) or women (p=0.118). The frequency of junk food consumption did not show a significant correlation with BMI in women (p=0.292). For men, the frequency of junk food consumption had a strong positive link with BMI (r=0.490, p=0.008). In conclusion, sleep quality did not connect with BMI in either gender; nevertheless, increased junk food consumption was linked to a higher BMI exclusively among male students.