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The Effect of Triponyl Sulphate on Fetuses Development and Placental Abnormalities in Inducing Preeclampsia of Rattus norvegicus animal model Purwatiningsih, Wawid; Aryani, Dhita Evi; Vidiastuti, Dian; Oktanella, Yudit; Firmawati, Aulia
Veterinary Biomedical and Clinical Journal Vol. 1 No. 1 (2019)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (672.49 KB) | DOI: 10.21776/ub.VetBioClinJ.2019.001.01.6

Abstract

Preeclampsia is one of the obstetrical problems that can cause maternal and fetal morbidity and mortality. Preeclampsia causes the fetus born prematurely and low fetal weight. This is caused by high blood pressure which causes decrease of blood delivery to the placenta, so the supply of oxygen and food to the fetus decreases. As a result, fetal development inhibits and trigger born prematurely. More fatal, this disease cause the release of placental tissue from the uterus prematurely. The aim of this study was to determine the effect of administration of triponyl sulfate as induction of increased blood pressure in preeclampsia animal models, fetal development with alizarin red staining and placental abnormalities. The experimental animals were rats Rattus norvegicus mated with male rats monomating , 4 months old and 250-300 grams body weigh. Pregnant female rats were induced by triponyl sulfate 70 mg / kg BW (k +) and without induced by triponyl sulfate (k-). The results of the study showed that there were formation of the sternal bone in k- and malformation of the sternum bone at k +. Placental abnormalities occured in k +, it could be seen in the presence of ghos villi in blood vessel abnormalities in the preeclampsia placenta caused by there was no invation of trophoblast cells in the whole or partial spiral arteries and the mean of blood pressure increased.
Treatmant of Malunion Comminuted Fracture Os Tibia in Maltese Dog: Penanganan Kasus Malunion Comminuted Fracture Os Tibia pada Anjing Maltese Putri, Novi Aprilia Shania; Rudi H. Panggabean; Vidiastuti, Dian
Veterinary Biomedical and Clinical Journal Vol. 5 No. 1 (2023)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2023.005.01.1

Abstract

A comminuted fracture is a type of fracture where the affected bone is divided into three or more pieces of different sizes. Improper handling of fractures can potentially lead to malunion and chronic pain. In malunion, the fractured bones are fused but in an abnormal position. Malunion occurs due to inaccurate bone reduction or excessive mobilization during the healing period. The purpose of this article is to describe a surgical method in handling a case of comminuted fracture of the tibia in a dog. A Maltese dog, 3 kg weight, was brought to the clinic due to gait immobility with lifting the right hind leg and limping. In the previous month, the dog suffered from a comminuted fracture of the right tibia and had been treated with plates and screws. During the physical examination, the dog showed good general condition, while the rear right leg was raised. Radiographic results at the medio-lateral and caudo-cranial projection showed the malunion bone due to a shift in the fracture fragment of the diaphysis of right tibia after plate and screw implantation in the comminuted fracture. In the present correction, the plate and screw were replaced by intra-medullary pins combined with wire implementing the Open Reduction and Internal Fixation (ORIF) method. Atropine sulfate premedication was given subcutaneously at 0.02 mg/kgBW. Anesthesia was induced using a combination of 10% ketamine and 2% xylazine, and maintained by a 2% isoflurane inhalation. Postoperative therapy given included Penicillin Procaine G®, Dexamethasone® (0.5 mg/kgBW,IM), Tramadol® (5 mg/kgBW,IM), Viccillin® (10 mg/kgBW,IM), and Cyanocobalamin® (100 mcg/ kgBW, IM). There was no postoperative complication observable, and the patient was brought home on the third day post-surgery when its affected feet was able to touch the floor. The study showed that ORIF method could be performed to correct malunion in a case of comminuted tibia fracture.
Anaesthesia Management Strategies for Cystotomy in Dogs Kisya, Lintan Ayu; Vidiastuti, Dian
Veterinary Biomedical and Clinical Journal Vol. 5 No. 2 (2023)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2023.005.02.2

Abstract

Geriatric and Portosystemic shunts could increase the risk of anaesthetic drug toxicity during cystotomy in dogs experiencing urolithiasis. The study reviewed the use of anaesthesia in cystotomy in dogs, from case reports published during the period between 2012-2022, retreived using the Google Scholar search engine. Inclusion criteria for the review involved a detailed description of the examinations and treatments. Ten articles were reviewed and showed that the most frequently used premedication, - induction anaesthesia, and maintenance anaesthetic agents were Xylazine, Ketamine, and Isoflurane, consecutively. In geriatric cases, Atropine Sulphate, Diazepam and Xylazine were used as premedication, while Ketamine and Propofol were used as induction anaesthesia. In large breeds, Xylazine, Meloxicam, Atropine Sulphate, Diazepam, and Buprenorphine were used as premedication, while Ketamine, Diazepam, and Propofol were used as – induction anaesthesia, and Isoflurane was used as maintenance anaesthesia. Considerations in using anaesthesia in different medical conditions are discussed.
Surgical Procedure for Pyometra and Mammae Tumor Treatment in a Pitbull Dog Rickyawan, Nofan; Virgiantari, Cheptien Winda; Lesmana, Muhamad Arfan; Vidiastuti, Dian
Jurnal Medik Veteriner Vol. 5 No. 1 (2022): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol5.iss1.2022.109-118

Abstract

Pyometra is an infection or inflammation of the uterine wall characterized by the accumulation of pus in the uterine lumen. Predisposing factors include age, breed, bacterial infection, and hormones. Another disease that is often correlated with an imbalance in reproductive hormones is mammary tumors. A 7-year-old unspayed female Pitbull dog weighed 27.9 kg has clinical symptoms of frequent discharge of mucopurulent reddish-brown discharge with a foul odor from the vagina. The left mammary glands of the second, third, and fourth nipples have lumps about 20 cm in diameter, are solid in consistency, well-defined, the same color as the skin surface, and can be moved. Diagnosis performed on physical examination, hematology, blood chemistry, and cytology was pyometra and mammary tumors. Treatment was done by ovariohysterectomy and unilateral mastectomy. Post-surgery therapy was enrofloxacin 5 mg/kg, ketoprofen 2 mg/kg, phytomenadione 1 mg/kg, and Biodin® 0.1 ml/kg, followed by intensive surgical wound care. The patient recovered after two months of treatment.
Morfometri Pencitraan Gelembung Renang Dan Potensi Penurunan Denyut Jantung Pada Penggunaan Minyak Cengkeh Sebagai Anestetik Ikan Nila Jatimbulan (Oreochromis niloticus) Vidiastuti, Dian; Arfiati, Diana
Jurnal Penelitian Pendidikan IPA Vol 9 No 9 (2023): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i9.5178

Abstract

Jatimbulan tilapia has the potential to be developed in Indonesia because it is easy to cultivate. The use of anesthetics in the dry transportation process and medical examination of fish often uses clove oil because it is cheap and easy to obtain. This research was conducted to determine the effect of using clove oil as an anesthetic on the swim bladder and heart rate. 35 adult Jatimbulan tilapia fish, 4 months old, male, were divided into 7 treatment groups, namely control (P1), clove oil anesthesia induction dose of 20 ppm (P2), 30 ppm (P3), 40 ppm (P4), 50 ppm ( P5), 60 ppm (P6) and 70 ppm (P7). The swimming pool measurement method uses lateral projection radiography imaging and echocardiography to measure heart rate. The results of the Tukey test showed that there was no difference in the average length of the swim bladder for each group, while the doses of P5 (50 ppm) and P6 (60 ppm) caused an increase in the width of the swim bladder compared to P1 (control) and P2 (20 ppm). Group P7 (70 ppm) had the lowest average heart rate compared to all groups, namely 49 ± 3.69 times per minute. The conclusion of this research is that the use of clove oil at a dose of 20-70 ppm for anesthesia of Jatimbulan tilapia does not affect the dimensions and structure of the swim bladder, but it is necessary to anticipate a decrease in heart rate that occurs with increasing doses.