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Journal : Veterinary Biomedical and Clinical Journal

The Effect of Triponyl Sulphate on Fetuses Development and Placental Abnormalities in Inducing Preeclampsia of Rattus norvegicus animal model Purwatiningsih, Wawid; Aryani, Dhita Evi; Vidiastuti, Dian; Oktanella, Yudit; Firmawati, Aulia
Veterinary Biomedical and Clinical Journal Vol. 1 No. 1 (2019)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (672.49 KB) | DOI: 10.21776/ub.VetBioClinJ.2019.001.01.6

Abstract

Preeclampsia is one of the obstetrical problems that can cause maternal and fetal morbidity and mortality. Preeclampsia causes the fetus born prematurely and low fetal weight. This is caused by high blood pressure which causes decrease of blood delivery to the placenta, so the supply of oxygen and food to the fetus decreases. As a result, fetal development inhibits and trigger born prematurely. More fatal, this disease cause the release of placental tissue from the uterus prematurely. The aim of this study was to determine the effect of administration of triponyl sulfate as induction of increased blood pressure in preeclampsia animal models, fetal development with alizarin red staining and placental abnormalities. The experimental animals were rats Rattus norvegicus mated with male rats monomating , 4 months old and 250-300 grams body weigh. Pregnant female rats were induced by triponyl sulfate 70 mg / kg BW (k +) and without induced by triponyl sulfate (k-). The results of the study showed that there were formation of the sternal bone in k- and malformation of the sternum bone at k +. Placental abnormalities occured in k +, it could be seen in the presence of ghos villi in blood vessel abnormalities in the preeclampsia placenta caused by there was no invation of trophoblast cells in the whole or partial spiral arteries and the mean of blood pressure increased.
Treatmant of Malunion Comminuted Fracture Os Tibia in Maltese Dog: Penanganan Kasus Malunion Comminuted Fracture Os Tibia pada Anjing Maltese Putri, Novi Aprilia Shania; Rudi H. Panggabean; Vidiastuti, Dian
Veterinary Biomedical and Clinical Journal Vol. 5 No. 1 (2023)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2023.005.01.1

Abstract

A comminuted fracture is a type of fracture where the affected bone is divided into three or more pieces of different sizes. Improper handling of fractures can potentially lead to malunion and chronic pain. In malunion, the fractured bones are fused but in an abnormal position. Malunion occurs due to inaccurate bone reduction or excessive mobilization during the healing period. The purpose of this article is to describe a surgical method in handling a case of comminuted fracture of the tibia in a dog. A Maltese dog, 3 kg weight, was brought to the clinic due to gait immobility with lifting the right hind leg and limping. In the previous month, the dog suffered from a comminuted fracture of the right tibia and had been treated with plates and screws. During the physical examination, the dog showed good general condition, while the rear right leg was raised. Radiographic results at the medio-lateral and caudo-cranial projection showed the malunion bone due to a shift in the fracture fragment of the diaphysis of right tibia after plate and screw implantation in the comminuted fracture. In the present correction, the plate and screw were replaced by intra-medullary pins combined with wire implementing the Open Reduction and Internal Fixation (ORIF) method. Atropine sulfate premedication was given subcutaneously at 0.02 mg/kgBW. Anesthesia was induced using a combination of 10% ketamine and 2% xylazine, and maintained by a 2% isoflurane inhalation. Postoperative therapy given included Penicillin Procaine G®, Dexamethasone® (0.5 mg/kgBW,IM), Tramadol® (5 mg/kgBW,IM), Viccillin® (10 mg/kgBW,IM), and Cyanocobalamin® (100 mcg/ kgBW, IM). There was no postoperative complication observable, and the patient was brought home on the third day post-surgery when its affected feet was able to touch the floor. The study showed that ORIF method could be performed to correct malunion in a case of comminuted tibia fracture.
Anaesthesia Management Strategies for Cystotomy in Dogs Kisya, Lintan Ayu; Vidiastuti, Dian
Veterinary Biomedical and Clinical Journal Vol. 5 No. 2 (2023)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2023.005.02.2

Abstract

Geriatric and Portosystemic shunts could increase the risk of anaesthetic drug toxicity during cystotomy in dogs experiencing urolithiasis. The study reviewed the use of anaesthesia in cystotomy in dogs, from case reports published during the period between 2012-2022, retreived using the Google Scholar search engine. Inclusion criteria for the review involved a detailed description of the examinations and treatments. Ten articles were reviewed and showed that the most frequently used premedication, - induction anaesthesia, and maintenance anaesthetic agents were Xylazine, Ketamine, and Isoflurane, consecutively. In geriatric cases, Atropine Sulphate, Diazepam and Xylazine were used as premedication, while Ketamine and Propofol were used as induction anaesthesia. In large breeds, Xylazine, Meloxicam, Atropine Sulphate, Diazepam, and Buprenorphine were used as premedication, while Ketamine, Diazepam, and Propofol were used as – induction anaesthesia, and Isoflurane was used as maintenance anaesthesia. Considerations in using anaesthesia in different medical conditions are discussed.