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All Journal Jurnal Ilmiah Farmasi Farmasyifa Jurnal Indah Sains dan Klinis Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Vivi Eulis Diana
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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AKTIVITAS ANTI OKSIDAN DAN EVALUASI SEDIAAN MASKER PEEL-OFF EKSTRAK ETANOL RIMPANG KUNYIT PUTIH (Curcuma zedoaria Roscoe Hendri Faisal; Adek Chan; Hanafis Sastra Winata; Vivi Eulis Diana; Widya Atika
Jurnal Ilmiah Farmasi Farmasyifa Vol 6, No 1 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiff.v6i1.9085

Abstract

Rimpang kunyit putih banyak dipergunakan pada pengobatan tradisional dan industri farmasi karena mempunyai kandungan senyawa flavonoid dan polifenol. Tujuan penelitian ini adalah untuk mengetahui apakah sediaan masker peel-off bersifat sebagai antioksidan dengan konsentrasi ekstrak etanol rimpang kunyit putih 10%, 20% dan 30%. Pembuatan ekstrak dilakukan dengan metode maserasi menggunakan pelarut etanol 96%. Pembuatan formulasi standar sediaan masker peel-off dengan ekstrak rimpang kunyit putih menggunakan bahan dasar polivinil alkohol, Hydroxyl Propyl Methyl Cellulose (HPMC),triehtanolaminea (TEA),gliserin,metil paraben,propil paraben dan akuades. Evaluasi sediaan yang dilakukan  meliputi uji organoleptis, pH, homogenitas, daya sebar, waktu kering, iritasi dan pengujian aktivitas antioksidan menggunakan spektrofotometri UV-Visibel dengan metode DPPH berdasarkan nilai pemerangkapan radikal bebas (nilai IC50).Berdasarkan hasil penelitian diketahui bahwa sediaan masker berbentuk setengah padat berwarna kuning tua hingga coklat, berbau khas rimpang kunyit putih. pH yang dihasilkan 6,0-6,3, sediaan homogen tidak ada butiran kasar, daya sebar 5,1-5,5 cm, waktu kering 14-16 menit dan tidak menyebabkan iritasi. Hasil pengujian antioksidan menunjukkan bahwa masker peel-off dengan ekstrak rimpang kunyit putih memiliki sifat antioksidan sebesar 99,94 (µg/mL), 83,21 µg/mL dan 60,88µg/mL pada konsentrasi ekstrak 10%,20% dan 30%. Kesimpulan penelitian ini adalah ekstrak rimpang kunyit putih (curcuma zedoaria roscoe) dapat diformulasikan menjadi masker peel-off .Ketiga formulasi masker memiliki sifat fisik yang baik dan memiliki sifat antioksidan dalam kategori kuat. Masker peel_off yang memiliki nilai antioksidan terbaik adalah formulasi F3 sebesar 60,88µg/ml.
Hubungan Pengetahuan dan Sikap Kaum Ibu Punge Blang Cut-Jaya Baru pada Preventivasi Demam Berdarah Lukmanul Hakim; Adek Chan; Suprianto; Vivi Eulis Diana
Jurnal Indah Sains dan Klinis Vol 4 No 2 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i2.04

Abstract

Background: According to the World Health Organization, annually there are around 50.0-100.0 million cases of dengue fever worldwide, with 0.25-0.50 million of them being cases of dengue hemorrhagic fever (DHF) which causes around 24,000 death. Objective: The study was directed at evaluating the knowledge and attitudes of mothers regarding dengue prevention in Punge Blang Cut, Jaya Baru. Method: A cross-sectional design was used in the study conducted in April 2019. Around 176 heads of families in the village were sampled. Data was collected through a questionnaire with the Chi-Square test at a significance of 0.05. Results: The majority of respondents had sufficient knowledge (46.6%), their mothers had a positive attitude towards dengue prevention (73.3%), and 52.3% of respondents took sufficient preventive measures. Conclusion: The majority of mothers have sufficient knowledge and have a positive attitude towards preventing dengue fever. It is recommended to increase public knowledge and awareness regarding the handling and prevention of dengue fever through appropriate medical and traditional methods.
EFEKTIVITAS ANTI JERAWAT SEDIAAN KRIM EKSTRAK ETANOL DAUN NANGKA (Artocarpus heterophyllus Lam.) TERHADAP Propionibacterium acnes Hafizhatul Abadi; Vivi Eulis Diana; Jacub Tarigan; Tetty Noverita Khairani; Tri Sundari
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 7 No. 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.419

Abstract

Jackfruit (Artocarpus heterophyllus Lam.) leaves have medicine potential, such as an antibacterial in anti-acne treatment contain flavonoids, tannins and saponins. The study aims to determine whether the ethanol extract of jackfruit leaves 96% can be formulated and determined the effectiveness of concentration preparation in inhibiting the Propionibacterium acnes bacteria. The preparation of cream preparations used a concentration of 20%, 30% and 40% jackfruit leaf ethanol extract. Then carried out the evaluation test of the preparation including the organoleptic test, homogeneity test, spreadability test, and pH test. Furthermore, the antibacterial effectiveness test was carried out by using the diffusion method. The results of evaluation test for cream preparations which included organoleptic tests with the results of three concentrations meeting the requirements, the homogeneity test and the dispersion test of the preparations, the results meet the specified conditions and the results of the pH test with the three concentrations of preparations that met the specified pH requirements. And it can inhibit the growth of Propionibacterium acnes bacteria with an inhibition zone of 7.5 mm at a concentration of 20%, 11 mm at a concentration of 30%, and 11.7 mm at a concentration of 40%. Antibacterial effectiveness test using positive control had an inhibition zone of 25.9 mm. The conclusion of this study is that the ethanol extract of jackfruit leaves can be formulated into anti-acne cream preparations.
Co-Authors Abadi, Hafizhatul Adek Chan Hendri Faisal Jacub Tarigan Lukmanul Hakim Suprianto Suprianto Tetty Noverita Khairani Tri Sundari Widya Atika Winata, Hanafis Sastra