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All Journal The Avicenna Medical Journal
Risahmawati . .
Department Of Community,Occupational And Family Medicine, Faculty Of Medicine, UIN Syarif Hidayatullah, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The Effect of Ramadan Fasting on Serum Malondialdehyde Levels as Indicator of Oxidative Stress and Cellular Damage Annisa Nadia Utami; Risahmawati . .; Muniroh . .
The Avicenna Medical Journal Vol 3, No 1 (2022)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v3i1.19716

Abstract

Background: Ramadan fasting is one of five pillars of Islam. Fasting is to refrain from eating and drinking from sunrise (sahur) to sunset (ifthar). Ramadan fasting has been shown to impact on body systems in different manners. One of the benefits of Ramadan fasting is protection against oxidative stress and cellular damage. Malondialdehyde (MDA) is a product of free radicals (hydroxil radicals) with polyunsaturated fatty acids (PUFAs) produced from lipid peroxidation of cell membranes. This paper aims to determine the effect of Ramadan fasting on serum MDA levels.Methods:  The design of this study is quasiexperimental with one group pre and post design. The sample of this study was 16 preclinical students of FK UIN Syarif Hidayatullah Jakarta who performed Ramadan fasting for 17 consecutive days. Blood samples were taken 1 day before Ramadan fasting and 18 days of Ramadan fasting to measure serum MDA levels. The study was conducted in the biochemical laboratory of FK UIN Syarif Hidayatullah.Results: The mean serum MDA levels before fasting was 0.90 ± 0.54 nmol/mL. The median value of serum MDA levels after fasting was 0.43 nmol/mL, with a range between 0.03 - 2.75 nmol/mL. Ramadan fasting decreases serum MDA levels, but the decrease that occurs on the 17th day of Ramadan fasting was not significant (p> 0.05). There was an increase in serum MDA levels in 4 subjects (25%) after Ramadan fasting.Conclusion: Ramadan fasting can reduce serum MDA levels as a marker of oxidative stress and cell damage. Further study is needed to investigate the various results in serum MDA levels after fasting.
Role of Physician’ Characteristics in Drug Prescription: Evaluation From Drug Database in Improving Prescribing Regulation Flori R. Sari; Saiful Anwar; Risahmawati Risahmawati; Marita Fadhilah; Fika Ekayanti
The Avicenna Medical Journal Vol 4, No 1 (2023)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v4i1.29878

Abstract

Introduction: Drugs prescribing is the most important skill for physicians and is strictly regulated by the government. However, factors that contribute to the drug prescribing are not determined yet. The aim of this study is to identify the possible role of physician character in drug prescribing at primary health centers (PHC).Method: A cross-sectional study was purposely done over fourteen-days at PHCs of Tangerang Districts. All prescriptions (n=2410) registered in the PHC drug-alert system (CIDIA Database) were analyzed descriptively.Result: From 2410 prescriptions registered in the PHC drug alert system, 15% prescriptions were prescribed by male physicians and 85% by the females. During the study, there were 964 drugs prescribed by 6 male physicians, 161 drugs per physician in average. There were 5584 drugs prescribed by 12 female physicians, 465 drugs per physician on average. Female physicians tended to prescribe 4 or more drugs compared to its male counterpart at 14% (p=0.006). However, there was no significant difference of drug interactions observed in the prescriptions prescribed by male or female physicians (p>0.05).Discussion: We identified that physician characteristics including gender played a significant role in the drug prescribing process especially the number of drugs prescribed. Therefore, considering gender differences in prescribing drugs may help the PHCs to improve a better management in drug safety and to comply with the government prescribing regulation.
Role of Physician’ Characteristics in Drug Prescription: Evaluation From Drug Database in Improving Prescribing Regulation Sari, Flori R.; Anwar, Saiful; Risahmawati, Risahmawati; Fadhilah, Marita; Ekayanti, Fika
The Avicenna Medical Journal Vol. 4 No. 1 (2023): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v4i1.29878

Abstract

Introduction: Drugs prescribing is the most important skill for physicians and is strictly regulated by the government. However, factors that contribute to the drug prescribing are not determined yet. The aim of this study is to identify the possible role of physician character in drug prescribing at primary health centers (PHC).Method: A cross-sectional study was purposely done over fourteen-days at PHCs of Tangerang Districts. All prescriptions (n=2410) registered in the PHC drug-alert system (CIDIA Database) were analyzed descriptively.Result: From 2410 prescriptions registered in the PHC drug alert system, 15% prescriptions were prescribed by male physicians and 85% by the females. During the study, there were 964 drugs prescribed by 6 male physicians, 161 drugs per physician in average. There were 5584 drugs prescribed by 12 female physicians, 465 drugs per physician on average. Female physicians tended to prescribe 4 or more drugs compared to its male counterpart at 14% (p=0.006). However, there was no significant difference of drug interactions observed in the prescriptions prescribed by male or female physicians (p>0.05).Discussion: We identified that physician characteristics including gender played a significant role in the drug prescribing process especially the number of drugs prescribed. Therefore, considering gender differences in prescribing drugs may help the PHCs to improve a better management in drug safety and to comply with the government prescribing regulation.
Co-Authors Annisa Nadia Utami Fadhilah, Marita Fika Ekayanti Flori R. Sari Marita Fadhilah Muniroh Muniroh Saiful Anwar Sari, Flori R.