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All Journal Medula PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JURNAL KESEHATAN: JURNAL ILMIAH MULTI SCIENCES Indonesian Journal of Pharmacy and Natural Product
Dwi Aulia Ramdini
Universitas Lampung
Agriculture, Biological Sciences & Forestry Economics, Econometrics & Finance Education Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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UJI ANTIBAKTERI EKSTRAK ETANOL JAHE MERAH (Zingiber Officinale Var Rubrum Rhizoma) TERHADAP BAKTERI Staphylococcus aureus Rizki Nisfi Ramdhini; Dwi Aulia Ramdini; Citra Yuliyanda Pardilawati
Jurnal Kesehatan : Jurnal Ilmiah Multi Sciences Vol 12 No 02 (2022): JURNAL KESEHATAN : JURNAL ILMIAH MULTI SCIENCES
Publisher : STIK SITI KHADIJAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52395/jkjims.v12i02.351

Abstract

Jahe merah (Zingiber Officinale Var Rubrum Rhizoma) merupakan tumbuhan yang banyak ditemukan di Indonesia. Masyarakat lokal sering memanfaatkan rimpangnya untuk mengobati berbagai penyakit sebagai antibakteri, antioksidan, antiinflamasi, analgesik, diuretik, antijamur, antikanker, dan antivirus. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dari ekstrak etanol jahe merah terhadap bakteri Staphyococcus aureus. Penelitian ini dilakukan melalui tahap maserasi, skrining fitokimia, pengujian aktivitas antibakteri ekstrak jahe merah dengan penentuan zona hambat. Metode penelitian skrining fitokimia dilakukan dengan uji warna menggunakan berbagai pereaksi. Teknik analisis data dilakukan dengan uji One Way Anova. Hasil penelitian pada skrining fitokimia diperoleh positif mengandung alkaloid, terpenoid, flavonoid, saponin dan tanin. Hasil rata-rata zona diameter ekstrak daun etanol jahe merah pada Staphylococcus aureus dengan konsentrasi 40%, 60%, 80% adalah 8 mm, 8,2 mm, 9,3 mm dan 10 mm. Hasil analisis One Way Anova pada uji antibakteri dengan nilai sig 0,00< 0,05 menunjukan adanya perbedaan yang signifikan dari masing-masing konsentrasi terhadap daya hambat. Kondisi ini menunjukkan bahwa ekstrak etanol jahe merah memiliki aktivitas terhadap Staphylococcus aureus.
Hubungan Paritas Dengan Kejadian Kanker Serviks: Tinjauan Pustaka Nathasya Karren Zeta Nathasya Karren Zeta; Rasmi Zakiah Oktarlina; Dwi Aulia Ramdini; M. Fitra Wardhana
Medula Vol 13 No 4 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i4.739

Abstract

Cervical cancer is a malignancy of the uterine cervix. Cervical cancer is one of the cancers that most often causes death in women in the world, especially in developing countries where one of the main causes is infection with the Human Papilloma Virus (HPV). The incidence of cervical cancer both in Indonesia and in the world tends to increase from year to year. The latest data shows that in 2018 there were 570,000 cases of cervical cancer in the world and in 2013 as many as 98,692 cases of cervical cancer occurred in Indonesia. According to the American Cancer Society, factors that can increase the risk of developing cervical cancer are HPV infection, family history of cervical cancer, use of hormonal birth control types, sexual behavior, age, parity, inappropriate diets that tend to be unhealthy diets and smoking habits. The number of parity of a woman associated with the incidence of cervical cancer. This is because every delivery, the cervix will experience trauma during the remodeling process. Deviations during the remodeling process cause changes in the extracellular components which impact important molecules that act as anticancer, namely E-Cadherin where the content will decrease in the cervical membrane so that the risk of cervical cancer will increase.
Pengetahuan dan Persepsi Apoteker Terhadap Penggunaan Obat Off-Label di Indonesia: Pharmacist's Knowledge and Perception of Off-Label Drugs Use in Indonesia Dwi Aulia Ramdini; Sarmoko; Ihsanti Dwi Rahayu; Muhammad Iqbal; Ramadhan Triyandi; Dika Pramita Destiani
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 01 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (487.807 KB) | DOI: 10.35473/ijpnp.v6i01.2219

Abstract

Off-label drugs are generally used in clinical practice but require close monitoring by health workers, especially pharmacists. Pharmacists need knowledge regarding the potential benefits and dangers of off-label medications to ensure the safety of drug users. This study aims to determine pharmacists' knowledge and perceptions of using off-label drugs in Indonesia. The study design used in this study was a cross-sectional study with an analytic observational approach using off-label drug-related questionnaires conducted online. Results of this study a total of 174 pharmacist respondents filled out a complete questionnaire with the result that 86% of the respondents had good knowledge regarding off-label drugs, and the rest were classified as poor (14%). Pharmacist respondents said they focused on safety (96.55%), efficacy (86.55%), medication history (72.99%), cost efficiency (61.49%), and also the target population (32.76%) in the use of off-label drugs. Based on factor analysis, the experience of preparing off-label drugs was significantly related to respondents' knowledge (p=0.041). In contrast, the factors of gender (p=0.777), age (p=0.677), last education (p=0.801), and years of service (p=0.541) there is no significant relationship. Conclusions of this study is The majority of pharmacist respondents in this study had good knowledge regarding the use of off-label drugs and agreed that pharmacists play an important role in monitoring the side effects of off-label use. In addition, almost all pharmacist respondents perceived that drug safety was the dominant factor for the consideration of off-label drug use. ABSTRAK Obat off-label umumnya digunakan dalam praktik klinis, namun dalam penggunaannya diperlukan pemantauan yang ketat oleh tenaga kesehatan, khususnya oleh apoteker. Pengetahuan terkait manfaat dan bahaya obat off-label diperlukan apoteker dalam menjamin keamanan dan keselamatan penggunaan obat. Penelitian ini bertujuan untuk mengetahui pengetahuan dan persepsi apoteker terhadap penggunaan obat off-label di Indonesia. Metode penelitian yang digunakan adalah studi cross-sectional dengan pendekatan observasional analitik melalui penggunaan kuesioner terkait obat off-label yang dilakukan secara online. Hasil penelitian sebanyak 174 responden apoteker terdapat 86% responden memiliki pengetahuan yang baik terkait obat off-label, dan sebagian lainnya tergolong kurang baik (14%). Responden apoteker menyatakan memiliki fokus terhadap faktor keamanan (96,55%), kemanjuran (86,55%), riwayat pengobatan (72,99%), efisiensi biaya (61,49%), dan target populasi (32,76%) dalam penggunaan obat off-label. Berdasarkan analisis faktor, pengalaman menyiapkan obat off-label berhubungan signifikan terhadap pengetahuan responden (p=0,041), sedangkan faktor jenis kelamin (p=0,777), umur (p=0,677), pendidikan terakhir (p=0,801), dan masa kerja (p=0,541) tidak terdapat hubungan signifikan. Kesimpulan penelitian ini adalah mayoritas responden apoteker memiliki pengetahuan yang baik terkait penggunaan obat off-label dan menyetujui bahwa apoteker berperan penting dalam monitoring efek samping penggunaan off label. Selain itu, hampir keseluruhan responden apoteker memiliki persepsi dimana faktor pertimbangan penggunaan obat off-label yang dominan adalah faktor terkait keamanan obat.
Gerakan Masyarakat Hidup Sehat Sadar Pangan Aman (Germas SAPA) dan Waspada Bahan Kimia Obat pada Jamu dan Obat Tradisional di Desa Baturaja Kecamatan Way Lima Kabupaten Pesawaran, Lampung: Healthy Living Community Movement for Safe Food Awareness (Germas SAPA) and Awareness of Chemical Substances in Jamu and Traditional Medicines in Baturaja Village, Way Lima District, Pesawaran Regency, Lampung Dwi Aulia Ramdini; Zulpakor Oktoba; Atri Sri Ulandari; Muhammad Iqbal Parabi; Afriyani Afriyani; Sri Wulan Mega; Donny Kesuma Wardhana
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 12 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i12.8208

Abstract

Gerakan Masyarakat Sehat Pangan Aman (Germas SAPA) and Waspada Bahan Kimia Obat in traditional medicines (BKO) are initiatives aimed at enhancing public health degrees in Indonesia. Baturaja Village, located in Way Lima, Pesawaran Regency, is one of the villages that had not yet been exposed to information about these programs. A team of lecturers from the University of Lampung, in collaboration with Balai Besar Pengawan Obat dan Makanan (BBPOM) in Bandar Lampung, conducted a public outreach session for the residents of Baturaja Village. This activity involved an educational session attended by 28 participants, including members of the PKK members and the general public. The session included educational presentations, the distribution of pocketbooks, and questions and answers. Pre- and post-test results on Germas SAPA and BKO awareness showed improved knowledge, with pre-test averages of 8.21 and 8.42, and post-test averages of 9.17 and 9.11. Positive responses were observed from the participants, as demonstrated by their enthusiastic inquiries related to food safety, herbal medicines, and general health. This initiative aims to enhance public understanding of food safety and traditional remedies, with PKK members expected to share this information within the community.
Co-Authors Afriyani Afriyani Atri Sri Ulandari Citra Yuliyanda Pardilawati Dika Pramita Destiani Donny Kesuma Wardhana Ihsanti Dwi Rahayu M. Fitra Wardhana Muhammad Iqbal Muhammad Iqbal Parabi Nathasya Karren Zeta Nathasya Karren Zeta Oktoba, Zulpakor Ramadhan Triyandi Rasmi Zakiah Oktarlina Rizki Nisfi Ramdhini Sarmoko Sarmoko Sri Wulan Mega