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Karakteristik Astrositoma di Indonesia Akbar Dwi juliardi NR; Rohadi Muhammad Rosyidi; Marie Yuni Andari
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.609

Astrocytoma is a primary brain tumor originating from astrocyte cells. The study was conducted using scientific literature review methods from various sources such as google search and google scholar with relevant keywords such as "prevalence of astrocytoma in Indonesia", "incidence of astrocytoma in Indonesia", "prevalence of astrocytoma in Indonesia", and "epidemiology primary brain tumor in Indonesia". Indonesia". After reading the titles and abstracts of the articles found, there were five research articles that met the criteria. From this literature study, there were 269 cases of astrocytoma in several hospitals in Indonesia in 2007-2018. At RSUP Dr. Hasan Sadikin Bandung in 2007–2009 astrocytomas were most commonly found in patients aged 20–34 years. In 2010–2012 astrocytoma was most commonly found in patients aged 31–40 years. And in 2013-2016 astrocytomas were most commonly found in patients aged 46 to 55 years. While at RSUP Dr. Wahidin Sudirohusodo in 2016 most astrocytomas were found in patients aged 20-29 years. Astrocytoma at RSUP Dr. Hasan Sadikin Bandung in 2007-2009 was mostly located in the frontal area, in 2010-2012 astrocytoma was mostly located in the cerebral hemispheres, and in 2013-2016 astrocytoma was mostly located in the cerebellum. At RSUP Dr. Wahidin Sudirohusodo astrocytoma mostly located in frontotemporal. At RSUP Dr. Hasan Sadikin Bandung astrocytoma is more often found in men, while in RSUP. Dr. Wahidin Sudirohusodo astrocytoma is more common in female patients

Penyuluhan Pentingnya Penggunaan Helm Standar Guna Menurunkan Angka Kejadian Cedera Otak di SMAN 2 Mataram Rohadi Muhammad Rosyidi; Bambang Priyanto; Januarman Januarman; Decky Aditya Zulkarnaen; Ahmad Taufik S; Bayu Tirta Dirja
Jurnal Gema Ngabdi Vol. 4 No. 3 (2022): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v4i3.294

Brain injury has the third largest prevalence of other injuries in Indonesia. Most brain injuries occur on highways as a result of motorcycling accidents. The only effective way to reduce the death rate from brain injury that occurs in motorcycle accidents is to wear a helmet. Cases of brain injury due to traffic accidents are often found in adolescents because of the lack of understanding of the importance of helmet use. Therefore, education is needed about the importance of using standard helmets when driving among teenagers. The counseling activity was carried out in one of the senior high schools (SMA) in Mataram with the dominant target of teenagers using motorized vehicles. The selected high school is SMA Negeri 2 Mataram. The method of implementing this counseling is by giving lectures on brain injury, the mechanism of trauma and brain injury and the importance of using standard head protective equipment (SNI helmets), playing videos about head trauma and interactive dialogue. The mandatory output that will be produced is in the form of research articles in the Unram Medical Journal. In addition, research results will be reported back to related fields as input and study material for traffic safety program activities in determining policies in planning, implementing, and evaluating programs as well as coordinating with related programs and sectors. The researcher will also provide a banner stand regarding the importance of using standard helmets for motorcycle riders at the activity location which can then be used as a medium of communication, information and education to the school students.

Hubungan Tingkat Pengetahuan Karang Taruna Desa Tentang Cedera Otak Sebelum dan Sesudah Penyuluhan di Desa Pesisir Senggigi Bambang Priyanto; Rohadi Muhammad Rosyidi; Januarman Januarman; Decky Aditya Zulkarnaen; Ahmad Taufik S; Bayu Tirta Dirja
Jurnal Gema Ngabdi Vol. 4 No. 3 (2022): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v4i3.297

Brain injury has the third largest prevalence of other injuries in Indonesia. Most brain injuries occur on highways as a result of motorcycling accidents. The only effective way to reduce the death rate from brain injury that occurs in motorcycle accidents is to wear a helmet. Cases of brain injury due to traffic accidents are often found in adolescents because of the lack of understanding of the importance of helmet use. Therefore, education is needed about the importance of using standard helmets when driving among teenagers. The counseling activity was carried out in one of the senior high schools (SMA) in Mataram with the dominant target of teenagers using motorized vehicles. The selected high school is SMA Negeri 2 Mataram. The method of implementing this counseling is by giving lectures on brain injury, the mechanism of trauma and brain injury and the importance of using standard head protective equipment (SNI helmets), playing videos about head trauma and interactive dialogue. The mandatory output that will be produced is in the form of research articles in the Unram Medical Journal. In addition, research results will be reported back to related fields as input and study material for traffic safety program activities in determining policies in planning, implementing, and evaluating programs as well as coordinating with related programs and sectors. The researcher will also provide a banner stand regarding the importance of using standard helmets for motorcycle riders at the activity location which can then be used as a medium of communication, information and education to the school students.

Karakteristik Pasien Amnesia Pasca Cedera Otak di Rumah Sakit Umum Daerah Provinsi Nusa Tenggara Barat Lalu Wahyu Alfian Muharzami; Rohadi Muhammad Rosyidi; Ilsa Hunaifi; Bambang Priyanto
Unram Medical Journal Vol 11 No 3 (2022): volume 11 no 3
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i3.653

Background: Traumatic Brain Injury (TBI) is a brain disorder caused by a traumatic process such as an impact, blow, or stab to the head, causing impaired brain function. Several external causes of TBI, such as falls, road traffic accidents, and beatings/assaults. Impaired memory function is one form of the neuropsychological disorder that can occur after injury. Post-Traumatic Amnesia (PTA) is a post-injury condition characterized by difficulty remembering things that were happened before or retaining information that has just happened. Methods: This research was conducted at West Nusa Tenggara Province General Hospital using a cross-sectional design and has passed the review of the research ethics team (ethical clearance). The number of research samples was 40 people with brain injury. We collected head CT scan results and interviews using the Galveston Orientation and Amnesia Test (TOAG) questionnaire. Sampling using a consecutive sampling method. Data are presented descriptively. Results: Of the 40 TBI patients, 33 patients had PTA (82.5%). Most patients with PTA are between 18 and 30 years of age (45.46%), most of them were male (81.8%), and most patients had high school educational levels (42.43%). Based on the severity of brain injury, most PTA patients had a mild brain injury (57.58%). Based on the head ct scan, most PTA patients had diffuse lesions (51.52%). Conclusion: TBI patients who experienced PTA were dominated by men aged 18 to 30 years and had a high school education level. In addition, the location of diffuse lesions is often seen in TBI patients with PTA.

Gambaran Imunohistokimia Synaptophisin pada Neuron Otak Tikus Pasca Mengalami Cedera Otak Traumatik: Immunohistochemistry of Synaptophisin in Rat Brain Neurons After Traumatic Brain Injury Rohadi Rohadi; Bambang Priyanto; Lale Maulin Prihatina; Decky Aditya Zulkarnaen; Januarman Januarman; Bayu Putra Wibowo; Muzzaki Hasnan Ali; Gibran Ihza Sukma
JURNAL SAINS TEKNOLOGI & LINGKUNGAN Vol. 9 No. 1 (2023): JURNAL SAINS TEKNOLOGI & LINGKUNGAN
Publisher : LPPM Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jstl.v9i1.420

TBI is mechanically followed by pathomechanisms that cause damage to surrounding neurons, such as cell and tissue necrosis, inflammation, cerebral edema, breakdown of the blood-brain barrier, and hyperthermia. The more severe the brain injury, the greater the impact on the inflammatory response. Therefore, this study aims to determine the histopathological description of edema in rat brain cells after TBI and to analyze the relationship between differences in trauma burden and histopathological features of brain cell inflammation, hematoma, and edema in mice after traumatic brain injury. This study uses an experimental observational-analytical research design. Sprague-Dawley mice were used as research subjects and divided into four cluster groups (and one control group) with varying trauma-loading interventions. The trauma loads given were 20 grams, 40 grams, 60 grams, and 80 grams. Following the trauma load application, the mice's brains were biopsied one hour after the intervention to observe histopathological features of inflammatory markers (synaptophysin) and brain cell edema. The data were then analyzed using the SPSS program. Twenty mice were included in this study. The results of the study showed that there was a mean load of 50 grams, and there is a mean synaptophysin percentage of 23.5%. There was a significant relationship between differences in trauma load and the percentage of post-TBI rat brain cell edema (p <0.001). There is a perfect and strong correlation between differences in trauma load and the percentage of synaptophysin (p=0.926). It was discovered that as the trauma load increased, there was a growing percentage of edema and inflammation in the histopathological features of the mice’s brains. There was a significant difference between the severity of trauma and the percentage of brain cell inflammation and edema one hour after brain injury in mice. The more severe the level of trauma given, the higher the percentage of inflammation and edema that occurs in rat brain cells. The result is especially notable since the inflammation and edema is found one hour within injury.

Optimalisasi Potensi Wisata (Gua Sumur, Gua Kelelawar dan Gua Prabu) di Desa Prabu Kecamatan Pujut Kabupaten Lombok Tengah Johan Trinanda Hermawan; I. MD. Arya Wiradana; Achmad Evin Kafrawi; Wira Risky Amanda; Kamariatul Kibtiah; Widya Rahayu; Thania Olang Tassya; Bq. Dina Ayuni A; Listia Putri; Meylia Arifathiyah; Rohadi Muhammad Rosyidi
Jurnal Gema Ngabdi Vol. 5 No. 1 (2023): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v5i1.325

Tourism is a recreational activity carried out with the intention of breaking away from the daily routine for a while. The tourist village is a combination of natural attractions, culture and creativity of the local community, supported by facilities that can attract tourists to visit the place. Prabu Village is one of the tourist destinations in Pujut District, Central Lombok. Even though it has advantages in natural beauty, unfortunately Prabu Village is still lacking in management and public awareness of the importance of existing tourism potential. Therefore, Unram Thematic KKN participants carried out community service in Prabu village with the theme 'Tourism and the Environment'. The purpose of this service is to introduce the tourism potentials in Prabu Village to the wider community. One of the programs carried out was by making a promotional video for Prabu Village which explained all the potential that the village had. Videos that have been made are then published on various social media (Youtube, Instagram, etc.), websites, and video platforms. With an effective promotional video, Prabu Tourism Village is expected to become an attractive tourist destination for both local and international tourists.

Hubungan Perbedaan Beban Trauma Dengan Gambaran Histopatologi Edema Sel Otak Tikus Pasca Cedera Otak Traumatik: The Relationship between Trauma Load Differences and Histopathological Description of Rat Brain Cell Edema Post Traumatic Brain Injury Bayu Putra Wibowo; Rohadi Rohadi; Lale Maulin Prihatina; Zikrul Haikal
JURNAL SAINS TEKNOLOGI & LINGKUNGAN Vol. 9 No. 1 (2023): JURNAL SAINS TEKNOLOGI & LINGKUNGAN
Publisher : LPPM Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jstl.v9i1.428

Traumatic brain injury is a condition of the head structure that is impacted or traumatized, causing disruption of brain function. This condition is one of the types of injuries that have the most severe effects on disability and death. Globally, 60 million people suffer from traumatic brain injury each year, with the most common complication being intracranial hemorrhage which increases the risk of death and disability. The incidence of traumatic brain injury is most common in the age group of children (0 - 4 years), adolescents and young adults (15-24 years) and the elderly (> 65 years). Where the most common causes are falls and vehicle accidents. This study aims to determine the histopathological description of edema in rat brain cells after traumatic brain injury and to analyze the relationship between differences in trauma burden and histopathological features of brain cell edema in rats after traumatic brain injury. This research is an experimental conducted by giving treatment to the object under study and then observing it. Sampling in this research will use purposive sampling. Where the researcher has determined the criteria of the sample to be used in the study so that it can represent the population. Based on the research conducted, it was found that there was a relationship between differences in trauma load and the percentage of brain cell edema in rats after experiencing traumatic brain injury. Where the greater the load given, the wider the surface of the brain that is experiencing edema. The results showed a significant edema appearance compared to the histopathological appearance of rat brain cells in normal samples. In addition, it was found that there was an increase in the percentage of areas with edema with a greater trauma load p=0.8156.

Hubungan Perbedaan Beban Trauma Dengan Gambaran Histopatologi Hematoma Otak Tikus Pasca Cedera Otak Traumatik: The Relationship between Trauma Load Differences and Histopathological Description of Rat Brain Hematoma Post Traumatic Brain Injury Gibran Ihza Sukma; Rohadi Rohadi; Lale Maulin Prihatina; Zikrul Haikal
JURNAL SAINS TEKNOLOGI & LINGKUNGAN Vol. 9 No. 1 (2023): JURNAL SAINS TEKNOLOGI & LINGKUNGAN
Publisher : LPPM Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jstl.v9i1.429

Traumatic brain injury is defined as trauma to the head that can cause physical, intellectual, emotional, social or behavioral changes. Traumatic brain injury is one of the leading causes of morbidity and mortality worldwide. Brain injury Traumatic disorders are among the most common disorders in neurology. in the brain, it accounts for 2 to 15% of all head injuries. This study aims to determine the histopathological picture of brain hemorrhage in rats after experiencing traumatic brain injury and to analyze the relationship between differences in trauma load and the histopathological appearance of brain hemorrhage in rats after experiencing traumatic brain injury. This research is an experimental study conducted by giving treatment to the object under study and then observing it. Sampling in this research will use purposive sampling. Where the researcher has determined the criteria of the sample to be used in the study so that it can represent the population. : The results of this study there was no significant relationship between the percentage of the degree of brain hematoma in rats after experiencing traumatic brain injury. These results explain that bleeding in the brain usually progresses about 4-8 hours after brain injury occurs. In addition, the percentage of bleeding areas with trauma burden was p = 2.890.

Hubungan Antara Perbedaan Beban Trauma Dengan Gambaran Histopatologi Inflamasi Otak Tikus Pasca Mengalami Cedera Otak Traumatik: Relationship Between Differences In Trauma Load With Histopathological Description Of Rat Brain Inflammation Post Traumatic Brain Injury Muzakki Hasnan Ali; Rohadi Rohadi; Lale Maulin Prihatina; Zikrul Haikal
JURNAL SAINS TEKNOLOGI & LINGKUNGAN Vol. 9 No. 1 (2023): JURNAL SAINS TEKNOLOGI & LINGKUNGAN
Publisher : LPPM Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jstl.v9i1.430

Brain injury is a damage to the brain, not congenital or degenerative, but caused by an attack or physical impact from the outside. Traumatic brain injury (TBI) is an injury that occurs when a force transmitted to the head or body causes neuropathological damage and dysfunction. TBI is one of the most common head injuries worldwide. This disorder affects 2% of the world's population each year and is the leading cause of death and serious disability in children and young adults. Getting hit or bumped into objects, motor vehicle crashes and falls, and intentional self-injury are the most common causes of TBI. This study aims to determine the histopathological description of brain inflammation in post-traumatic brain injury rats and analyze the relationship between differences in trauma burden and histopathological features of brain inflammation in post-traumatic brain injury rats. This research is an experimental study conducted by giving treatment to the object under study and then observing it. Sampling in this research will use purposive sampling. Where the researcher has determined the criteria of the sample to be used in the study so that it can represent the population. The results of this study indicate that there is a relationship between differences in trauma load and the percentage of rat brain inflammation after experiencing traumatic brain injury. The results of data analysis from this study for the Pearson test obtained a significance value of 0.00 so that there is a correlation between differences in trauma load and the percentage of brain cell inflammation in rats after experiencing traumatic brain injury. The Pearson correlation value of this data is 0.7621 which means a strong correlation. The results showed a significant inflammatory picture compared to the histopathological appearance of rat brain cells in normal samples.

Brain Tumor : Molecular Biology, Pathophysiology, and Clinical Symptoms Vanessa Essianda; Annisa Diyanabila Indrasari; Puji Widyastuti; Talitha Syahla; Rohadi Rohadi
Jurnal Biologi Tropis Vol. 23 No. 4 (2023): October - December
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i4.5585

Brain tumors are one of the most malignant tumors that occur in humans. It accounts for approximately 1.35% of all malignant neoplasms and 29.5% of cancer deaths. This article was written with the aim of knowing more about molecular biology, phatophysiology, and clinical symptoms of brain tumor. The method used is a literature review combined with a search for related sources from National Center for Biotechnology Information (NCBI), Google Scholar, and Research Gate. The results of this literature review of the articles carried out can be concluded that brain tumors often cause symptoms of physiological disorders, such as focal signs, fatigue and headaches or behavioral disorders including hallucinations, depression, anxiety, decreased attention and awareness. Brain tumors can also arise spontaneously without a family history or previous genetic inheritance pattern. In conclusion, cytogenetic and molecular abnormalities in brain tumors can be seen in numerical and structural chromosomal changes, gene amplification and overexpression, deletions and small-scale mutations and epigenetic deregulation.

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