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Rohadi
Fakultas Kedokteran, Universitas Mataram
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences

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Relationship Between S100 Protein Expression and Grading Meningioma Lale Maulin Prihatina; Rohadi; Bambang Priyanto; Decky Aditya Zulkarnaen; Abdul Syukur
Jurnal Penelitian Pendidikan IPA Vol 11 No 7 (2025): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i7.11529

Abstract

Meningioma is the most common type of benign brain tumor in adults and mostly originates from the meningeal layer of the brain and spinal cord. The prevalence of meningioma in the world is estimated to be about 24-30% of intracranial primary brain tumors. This tumor is classified into three groups based on grade, grade I (benign), grade II (atypical), and grade III (anaplastic). The S100 protein is not specific to meningiomas but some studies have shown that the expression of S100 protein is stronger in grade I meningiomas than in grade II and III meningiomas. Based on these findings, the authors are interested in analyzing whether there is a relationship between S100 expression and meningioma grading. The determination of S100 protein expression is very necessary as a reference in determining the prognosis and selection of the best therapy for patients. This research was carried out in the period from January 2021 to December 2021. 9 samples were included in this study according to the inclusion and exclusion criteria. The data was analyzed using SPSS version 26. The results of this study: A normality test was carried out with the Shapiro Wilk test and a value of p=0.34 (CI 95%) was obtained using Spearman analysis.
Co-Authors Abdul Syukur Achmad Evin Kafrawi Ahmad Taufik S Akbar Dwi juliardi NR Andari, Marie Yuni Annisa Diyanabila Indrasari Bambang Priyanto Bambang Priyanto Bambang Priyanto Bayu Putra Wibowo Bayu Tirta Dirja Bq. Dina Ayuni A Decky Aditya Zulkarnaen Decky Aditya Zulkarnaen Gibran Ihza Sukma I. MD. Arya Wiradana Ilsa Hunaifi Januarman Januarman Johan Trinanda Hermawan Kamariatul Kibtiah Lale Maulin Prihatina Lale Maulin Prihatina Lalu Wahyu Alfian Muharzami Listia Putri Meylia Arifathiyah Muzakki Hasnan Ali Muzzaki Hasnan Ali Puji Widyastuti Talitha Syahla Thania Olang Tassya Vanessa Essianda Widya Rahayu Wira Risky Amanda Zikrul Haikal