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All Journal JURNAL KIMIA SAINS DAN APLIKASI Jurnal Riset Kimia Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun
Dira Hefni
Universitas Andalas
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Journal : Jurnal Riset Kimia

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Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells Suryati, Suryati; Aziz, Enda Desriansyah; Efdi, Mai; Wahyuni, Fatma Sri; Hefni, Dira
Jurnal Riset Kimia Vol 12, No 1 (2021): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v12i1.364

Abstract

Lantana camara Linn is a family of Verbenaceae which grows wild and is widespread in various both tropical and sub-tropical countries. Isolation essential oil of the L. camara leaves extracted by hydrodistillation and were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results of GC-MS analysis show isocaryophyllene (14.39%), ρ-cymene (8.17 %), β-cubebene (7.8 %), α-pinene (7.64 %), and β-elemene (5.51 %) as the main compound. The cytotoxic activity of the isolated essential oil was highly toxic both to Artemia salina shrimp larvae (LC50 15.92 µg/mL) and to breast cancer cells T-47D (IC50 10.67 µM).
Co-Authors Adrial Adrial Aziz, Enda Desriansyah Dachriyanus Elidahanum Husni Endrinaldi Fatma Sri Wahyuni Gian Primahana Jepri Agung Priyanto Linosefa Linosefa Mai Efdi Meri Susanti Meri Susanti Muhammad Eka Prastya Netty Suharti Netty Suhatri Rafifa Ridha Saputro, Eko Bayu Satia, Bening Hawa Suhatri Suhatri Suryati Suryati Syafri, Suryati Syofyan Syofyan Yoneta Srangenge Zetryana Puteri Tachrim