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Innovative Diagnostic Approaches for TORCH Infections in Pregnancy: The Role of IgG Avidity and Affinity-Switchable Lateral Flow Assays Fauziah, Dina
Jurnal KESANS : Kesehatan dan Sains Vol 4 No 12 (2025): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v4i12.445

Abstract

Abstract Background: TORCH infections (Toxoplasma gondii, “Others,” Rubella virus, Cytomegalovirus, and Herpes simplex virus) are responsible for 2–3% of congenital anomalies worldwide and remain a significant cause of miscarriage, stillbirth, and lifelong disability. Early and accurate diagnosis is critical, yet conventional methods—serology and PCR—are costly, infrastructure-dependent, and often inaccessible in low-resource settings. Objective: This narrative review evaluates current TORCH diagnostic approaches and explores the potential of Affinity-Switchable Lateral Flow Assays (ASLFA), with emphasis on adapting the technology for IgG avidity testing to improve maternal screening. Content: Conventional serology provides information on IgM and IgG status but cannot reliably differentiate acute from past infections. IgG avidity testing refines interpretation, particularly for CMV and toxoplasmosis, by distinguishing recent primary infections from reactivations. However, avidity assays are laboratory-based and unavailable in many regions. ASLFA introduces a conditional “signal-on” design, expanding LFA utility to small molecules and functional readouts. Incorporating chaotropic reagents into ASLFA strips could enable on-site avidity measurement, while pathogen-specific antigens, such as CMV glycoprotein B (CMV34), may enhance specificity. Conclusion: ASLFA platforms integrating IgG avidity offer a promising, low-cost, point-of-care alternative to conventional tests. With further validation, they could democratize TORCH screening and improve maternal–fetal outcomes, particularly in resource-limited settings.
Pembentukan Bank Sampah Berkah (BSB) oleh Mahasiswa KKN Kelompok 67 Universitas Muhammadiyah Riau di Desa Lubuk Dalam Fikri, Khusnul; Ikhsan, Mukhlis; Tamba, Nela Ardiansih; Fauziah, Dina; Habiburrahman
Jurnal Pengabdian UntukMu NegeRI Vol. 7 No. 1 (2023): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v7i1.4318

Abstract

KKN is a form of student activity that involves serving the community. The purpose of this service activity is to socialize the creation of a waste bank by increasing public awareness of the importance of not littering. In addition, the waste bank is useful for all the people of Lubuk Dalam Village so they don't throw garbage or burn garbage, because from the garbage they can make money, crafts, etc., so they can boost the economy of the people in Lubuk Dalam Village. The method of implementing the activities was carried out through outreach to several schools and organizations in Lubuk Dalam Village. Through the "BERKAH" waste bank socialization activity in Lubuk Dalam Village, the community can also find out how to manage waste into goods of economic value. Garbage, which has been seen as trash by the general public, is something that causes an unpleasant, dirty, and disgusting smell. But with the existence of socialization activities regarding waste management, the smelly and dirty waste, if managed properly, can have economic value, as is currently being carried out by one of the waste banks, namely the "BERKAH" Waste Bank in Lubuk Village
Penerapan Model Think Talk Write untuk Meningkatkan Keterampilan Menulis Siswa SMP Ma’had Darussa’adah Cilongok Fauziah, Dina
Alinea: Jurnal Bahasa, Sastra dan Pengajaran Vol. 5 No. 1 (2025): Alinea: Jurnal Bahasa, Sastra, dan Pengajaran
Publisher : Bale Literasi: Lembaga Riset, Pelatihan & Edukasi, Sosial, Publikasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58218/alinea.v5i1.1353

Abstract

Penelitian ini bertujuan untuk mendeskripsikan penerapan model Think Talk Write (TTW) untuk menumbuhkan minat menulis siswa SMP Ma’had Darussa’adah Cilongok. Keterampilan menulis merupakan salah satu aspek pokok dalam pembelajaran bahasa, termasuk bahasa Indonesia. Dengan menulis, siswa dapat mengomunikasikan ide, gagasan, maupun pengalaman pribadinya melalui tulisan. Menulis juga dapat mengembangkan kemampuan berpikir kritis siswa dan membantu mereka dalam memahami materi. Namun, kenyataannya banyak siswa yang mengalami kesulitan dan kurang termotivasi dalam menulis. Model TTW dengan tahapan berpikir, berbicara, dan menulis diyakini dapat meningkatkan keterampilan menulis siswa. Penelitian ini menggunakan metode deskriptif kualitatif untuk memahami secara mendalam bagaimana model TTW diterapkan dan bagaimana dampaknya terhadap keterampilan menulis siswa. Subjek penelitian ini adalah siswa kelas VII SMP Ma’had Darussa’adah Cilongok. Teknik pengumpulan data meliputi observasi pembelajaran di kelas, wawancara mendalam siswa dengan guru, serta analisis dokumentasi berupa hasil tulisan siswa. Data yang terkumpul kemudian dianalisis melalui reduksi data, penyajian data dalam bentuk naratif, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa model TTW dapat meningkatkan minat menulis siswa melalui tahapan-tahapan yang meliputi aktivitas berpikir (Think), diskusi atau bertukar ide (Talk), dan menulis (Write). Model pembelajaran ini memberikan kesempatan bagi siswa untuk dapat memproses informasi secara lebih mendalam, bertukar ide atau pengalaman, dan mengorganisasikan pikiran sebelum dituangkan dalam sebuah tulisan sehingga siswa menjadi lebih termotivasi untuk menulis.
URGENSI MEMAHAMI DARAH KEWANITAAN DAN CARA MENSUCIKANYA DALAM ISLAM Fauziah, Dina; Darmila, Lilis
Almufida : Jurnal Ilmu-Ilmu Keislaman Vol 10, No 1 (2025): Almufida: Jurnal Ilmu-Ilmu Keislaman
Publisher : Universitas Dharmawangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46576/almufida.v10i1.7980

Abstract