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Endah Purnamasari
Universitas YARSI
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Gambaran Jumlah Trombosit dan Leukosit Saat Awal Masuk Rumah Sakit Pada Pasien Demam Dengue di RSUD Wates Periode April 2020 - April 2021 dan Tinjauannya Menurut Perspektif Islam Aulia Najmi Yatrib Ul Firdaus; Endah Purnamasari; Firman Arifandi
Junior Medical Journal Vol 1, No 4 (2022)
Publisher : Junior Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (368.361 KB) | DOI: 10.33476/jmj.v1i4.3025

Abstract

Latar belakang: Demam dengue adalah penyakit yang disebabkan oleh infeksi virus dengue yang ditularkan oleh gigitan nyamuk yang membawa virus dengue tersebut. Pada pasien dengue akan ditemukan kondisi rendahnya jumlah sel darah putih (leukopenia) dan kondisi rendahnya jumlah keping darah (trombositopenia). Leukopenia mencapai puncaknya sesaat sebelum demam turun dan normal kembali pada 2-3 hari setelah demam turun. Penurunan trombosit umumnya mengikuti turunnya leukosit. Dalam kitab Al furuq terdapat kaidah yang menyatakan bahwa hukum perantara mengikuti hukum tujuannya sehingga hukum pemeriksaan laboratorium dengue menjadi wajib mengikuti dengan hukum tujuannya yaitu untuk menjaga kesehatan.Metode: Jenis penelitian berupa deskriptif analitik dengan pendekatan cross sectional. Penelitian ini menggunakan hasil laboratorium pemeriksaan trombosit dan leukosit pasien demam dengue saat awal masuk RSUD Wates Periode April 2020 – April 2021. Analisis statistik dilakukan dengan Uji Korelasi Spearman untuk melihat hubungan antara usia dengan jumlah trombosit.Hasil: Pada pasien demam dengue saat awal diperiksa, jumlah leukosit menurun lebih dahulu sebesar 26 sampel (50%), jumlah leukosit dan trombosit menurun bersamaan sebanyak 15 sampel (28,8), jumlah leukosit dan trombosit normal sebanyak 7 sampel (13,5%), dan jumlah trombosit yang menurun lebih dahulu sebanyak 4 sampel (7,7%). Sehingga pada pasien demam dengue leukosit mengalami penurunan jumlah terlebih dahulu saat awal diperiksa. Kemudian berdasarkan uji statistik didapatkan nilai p lebih besar dari 0.05 sehingga dikatakan tidak terdapat hubungan yang signifikan antara usia dengan jumlah trombosit pada pasien demam dengue saat awal diperiksa.Kesimpulan: Penurunan trombosit mengikuti turunnya leukosit dan tidak ada hubungan antara usia dengan jumlah trombosit pasien demam dengue.
The Change in Hemoglobin Levels Before and After Cesarean Section and its Association with Age and Parity in Pregnant Women at Yarsi Hospital from January to October 2025 and Its Review According to Islam Tawfiqah Tsurayya; Syukrini Bahri; Afrizal Tw; Endah Purnamasari
Eduvest - Journal of Universal Studies Vol. 6 No. 4 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i4.52598

Abstract

This research aimed to analyze changes in hemoglobin levels before and after cesarean section and their association with maternal age and parity in pregnant women at YARSI Hospital from January to October 2025, as well as to review cesarean section from an Islamic perspective. This study employed a descriptive analytic design with a retrospective approach using secondary data obtained from medical records. A total of 292 pregnant women who underwent cesarean section and met the inclusion criteria were selected through consecutive sampling. Data analysis included univariate and bivariate analyses, using a paired t-test to assess differences in hemoglobin levels before and after cesarean section and a chi-square test to examine the relationship between age, parity, and changes in hemoglobin levels. The results showed that the mean hemoglobin level before cesarean section was 11.67 g/dL and after cesarean section was 11.78 g/dL, with no statistically significant difference between the two measurements. Furthermore, there was no significant association between maternal age or parity and changes in hemoglobin levels. From an Islamic perspective, cesarean section is permissible as it aligns with the principle of Hifz al-Nafs (protection of life) within Maqasid Shari‘ah, provided it is performed based on medical indications and aims to prevent harm to the mother and fetus. In conclusion, cesarean section at YARSI Hospital did not result in significant changes in hemoglobin levels and was not influenced by maternal age or parity, while remaining consistent with Islamic medical ethics.
The Relationship Between Sodium (Na⁺), Potassium (K⁺), and Chloride (Cl⁻) Electrolyte Disorders and Clinical Conditions in Elderly Patients in the Emergency Room of Yarsi Hospital for the Period January to December 2023 Mirshanti Muthia Khaliza; Syukrini Bahri; Afrizal Tw; Endah Purnamasari
Eduvest - Journal of Universal Studies Vol. 6 No. 4 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i4.53040

Abstract

Elderly patients are prone to electrolyte balance disorders due to aging, decreased organ function, hormonal changes, and high comorbidities. Imbalances of sodium, potassium, and chloride can affect neurological, muscle, and cardiovascular function, thus contributing to clinical instability in the emergency room. This study is an observational study of cross-cutting design analysis based on secondary data of medical records. The subject is an elderly patient (≥60 years old) who underwent an electrolyte examination at the Yarsi Hospital Emergency Room for the January-December 2023 period. Of the 1,730 visits, 315 patients met the inclusion criteria. The variables analyzed included sodium, potassium, chloride levels, as well as characteristics of age, sex, and clinical condition upon admission. Univariate and bivariate analysis was performed using the Chi-Square test. The majority of subjects were early elderly women. Hyponatremia is the most frequent disorder, followed by hypokalemia and hypochloremia. A total of 53% of patients experienced one electrolyte disorder, 36.2% two disorders, and 10.8% three disorders at once. The most common clinical conditions are low intake, chronic kidney disease, diabetes mellitus, infection, CVDNH, and vomiting. The Chi-Square test showed a significant association between clinical conditions and sodium (p=0.029), potassium (p=0.038), and chloride (p=0.027) impairments. Electrolyte disorders in the elderly in the emergency room are significantly related to the patient's clinical condition. Hyponatremia is most dominant and is associated with  poor intake, chronic kidney disease, infections, and diabetes.
Co-Authors Afrizal Tw Afrizal Tw Aulia Najmi Yatrib Ul Firdaus Firman Arifandi Mirshanti Muthia Khaliza Syukrini Bahri Syukrini Bahri Tawfiqah Tsurayya