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All Journal COPING (Community of Publishing in Nursing) E-Jurnal Medika Udayana Indonesian Journal of Tropical and Infectious Disease Syntax Literate: Jurnal Ilmiah Indonesia
Ni Luh Putu Eka Diarthini, Ni Luh Putu Eka
Bagian Parasitologi, Fakultas Kedokteran Universitas Udayana
Humanities Earth & Planetary Sciences Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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UJI AKTIVITAS BUAH MAHKOTA DEWA (PHALERIA MACROCARPA) SEBAGAI ANTIMALARIA PADA MENCIT YANG DIINFEKSI PLASMODIUM BERGHEI Juniantara, I Kadek Ade; Laksemi, Dewa Ayu Agus Sri; Damayanti, Putu Ayu Asri; Diarthini, Ni Luh Putu Eka
E-Jurnal Medika Udayana Vol 11 No 12 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i12.P15

Abstract

Malaria is a parasitic infection caused by Plasmodium sp. Malaria’s medication and prevention are known, but there is a problem of increasing Plasmodium resistance to antimalarial drugs such as drugs from the chloroquine class, to overcome this problem traditional medicine is chosen because it is safer and cheaper. God’s crown (Phaleria macrocarpa) is one of the plants commonly used for traditional medicine which contains several active substances, namely saponins, polyphenols, flavonoids, tannins, sterols, alkaloids and terpenoids which have potential as antimalarials which can be proven by observing the degree of parasitemia in the mice blood. This study was conducted in vivo using the Randomized Post Test Only Controlled Group method using 24 samples of mice which were divided into 4 groups. The negative control group was only 0.2 ml of RPMI as a treatment control and the treatment group was treated with God’s crown extract at doses of 1, 10, and 100 mg/kgBW, then the degree of parasitemia was examined in each mouse. The data analysis technique used is One Way ANOVA and Post Hoc test. The results obtained mean the degree of parasitemia in the control group, doses of 1 mg/kgBW, 10 mg/kgBW and 100 mg/kgBW respectively 41.70; 37.96; 31.55; and 37.0. The results based on the analysis using One Way ANOVA posttest, it was found that there were significant differences between the control group and treatment groups 1,2, and 3 with p value of 0.000 (p < 0.05). The results showed that the extract of the fruit of the God’s crown (Phaleria macrocarpa) could inhibit the growth of Plasmodium berghei, the best dose was found at a dose of 10 mg/kgBW.
BLASTOCYSTIS AND OTHER INTESTINAL PARASITES INFECTIONS IN ELEMENTARY SCHOOL CHILDREN IN DUKUH VILLAGE, KARANGASEM DISTRICT, BALI Diarthini, Ni Luh Putu Eka; Swastika, I Kadek; Ariwati, Luh; Isyaputri, Rahmadany; Fitri N, Moh. Yasin; Hidajati, Sri; Basuki, Sukmawati
Indonesian Journal of Tropical and Infectious Disease Vol. 7 No. 3 (2018)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1243.244 KB) | DOI: 10.20473/ijtid.v7i3.7323

Abstract

Blastocystis spp. is the most common enteric parasitic infection found in several community surveys from developing countries. Blastocystis infections may cause gastrointestinal symptoms, but also cause extraintestinal symptoms such as urticaria and joint pain. Blastocystis infection can also be asymptomatic or a carrier. However, the prevalence of Blastocystis infection in children has not yet been fully investigated in Indonesia, particularly in Bali Province. This study aimed to determine the prevalence of Blastocystis and other intestinal parasites in elementary school children stools in Dukuh village, Karangasem regency. A cross sectional study was conducted in September 2016. A total of 103 school children stools were collected by informed consent and parasites were examined by microscopy with wet mounts method using Lugol's iodine solution. Thirty-five school children were infected with Blastocystis spp. (35/103, 34%) that consisted of a single infection (29/35, 82.9%) and mix infection with other parasites (6/35, 17.1%). The mix infections were Blastocystis spp. and hookworm infection (1/6, 16.7%), Blastocystis spp. and Entamoeba coli (1/6, 16.7%), Blastocystis spp. and Giardia lamblia (2/6, 33.3%), Blastocystis spp. and Entamoeba histolytica/ Entamoeba dispar (1/6, 16.7%) and Blastocystis spp. and Entamoeba histolytica/ Entamoeba dispar and Giardia lamblia (1/6, 16.7%). The vacuolar forms of Blastocystis were dominantly found, in which was non-infectious form, whereas the infectious form is the cyst form and Blastocystis density was observed less than 5 cells per field of view at 400 magnification in all cases. This study concluded that the high prevalence of Blastocystis infection in elementary school children in Dukuh Village, Karangasem District, Bali that were dominantly single infections and several mix infections with other intestinal parasites. The high prevalence of Blastocystis infection in elementary school children suggested that it needs proper prevention measures for the children in this study area.
The Incidence and Characteristics of Misdiagnosed Covid-19 Patients with Dengue Fever Infections at Udayana University Hospital in 2020-2021 Adiputra, I Komang Hotra; Swastika, I Kadek; Diarthini, Ni Luh Putu Eka; Sudarmaja, I Made; Purnamasidhi, Cokorda Agung Wahyu
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 2 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i2.42119

Abstract

The rise in dengue fever in recent decades combined with the emergence of COVID-19 at the end of 2019, has created new challenges in the healthcare sector. This research is a descriptive study with a cross-sectional research design and using medical record data at Udayana University Hospital in 2020–2021. According to the study, 1.22% cases of misdiagnosis out of a total of 2365 suspected cases of COVID-19 were found at Udayana University. The majority of cases of misdiagnosis involved people older than 60 years, namely 7 people (24.1%) and were dominated by men, namely 17 people (58.6%). The most common symptoms found are fever, cough, shortness of breath, headache, and malaise, According to laboratory results, dominant patients have thrombocytopenia, followed by high alanine transaminase (ALT), high aspartate transaminase (AST), and leukopenia. The appearance of thrombocytopenia in cases of COVID-19 with dengue fever is the result of suppressed platelet synthesis due to virus induction which causes bone marrow suppression and platelet clearance. Leukopenia and leukocytosis may coexist with lymphopenia as an indicator of disease severity. The similarity of symptoms and laboratory results between COVID-19 and dengue fever allows for misdiagnosis that will affect the patient's management. Therefore, the aim of this study is to determine the misdiagnosis rate of COVID-19 with dengue fever at Udayana University Hospital in 2020–2021, so that it can reduce misdiagnosis of the disease.
PENYULUHAN EFEKTIF MENINGKATKAN PENGETAHUAN PEMBERANTASAN JENTIK NYAMUK AEDES AEGYPTI PADA ANAK SEKOLAH DASAR DI KOTA GIANYAR Damayanti, Putu Ayu Asri; Laksemi, Dewa Ayu Agus Sri; Diarthini, Ni Luh Putu Eka
Coping: Community of Publishing in Nursing Vol 12 No 1 (2024): Februari 2024
Publisher : Program Studi Sarjana Ilmu Keperawatan dan Profesi Ners, Fakultas Kedokteran, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/coping.2024.v12.i01.p03

Abstract

Nyamuk Aedes aegypti merupakan vektor penyakit Dengue yang masih endemis di Bali termasuk di Kabupaten Gianyar. Pencegahan penyakit dapat dilakukan dengan melakukan pengendalian vektor, yaitu dengan melakukan pemantauan dan pemberantasan jentik nyamuk. Pemberantasan jentik nyamuk dilakukan secara mandiri oleh segenap masyarakat dimulai dari seluruh anggota keluarga termasuk anak usia sekolah dasar (SD). Sebagai langkah awal anak SD harus dibekali pengetahuan tentang jentik nyamuk agar bisa melakukan pengendalian jentik. Salah satu metode peningkatan pengetahuan yang efektif adalah dengan metode penyuluhan. Penelitian ini bertujuan untuk mengetahui efektifitas penyuluhan dengan metode ceramah yang didukung media audiovisual pada anak SD Negeri 1 Kota Gianyar dalam meningkatkan pengetahuan tentang pemberantasan jentik nyamuk. Rancangan penelitian adalah analitik cross-sectional dengan melibatkan 92 siswa SD kelas V. Pengukuran pengetahuan dengan kuesioner dilakukan sebelum (pre-test) dan sesudah penyuluhan (post-test). Hasil penelitian menunjukan median skor pengetahuan pre-test dan post-test sebesar 50 dan 80. Terdapat perbedaan signifikan pengetahuan sebelum dan sesudah penyuluhan (p=<0,01) dengan peningkatan pengetahuan sebesar 37,5%. Dapat disimpulkan bahwa penyuluhan efektif meningkatkan pengetahuan anak SDN 1 Kota Gianyar. Pendidikan kesehatan tentang pemberantasan jentik sejak dini dilakukan secara rutin dan simultan demi mendukung program pengendalian vektor penyakit Dengue.
Hubungan Pengetahuan dengan Tindakan Pencegahan Primer Filariasis Limfatik pada Pedagang di Pasar Badung, Kota Denpasar, Provinsi Bali Purantara, Anak Agung Gede Wiweka Winahya; Swastika, I Kadek; Damayanti, Putu Ayu Asri; Diarthini, Ni Luh Putu Eka
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i1.56210

Abstract

Filariasis limfatik merupakan infectious disease dengan status menularkan cacing filaria dari kondisi inang manusia sakit menuju kondisi inang manusia sehat melalui gigitan vektor nyamuk. Masyarakat dengan tingkat pengetahuan yang rendah mengalami peningkatan jumlah kasus filariasis limfatik dibandingkan masyarakat dengan tingkat pengetahuan yang tinggi. Aktivitas perdagangan di area pasar tradisional selama 12-24 jam mengakibatkan pedagang rentan mengabaikan tindakan pencegahan filariasis limfatik. Penelitian dilaksanakan untuk menganalisis hubungan antara pengetahuan dengan tindakan pencegahan primer mengenai filariasis limfatik pada pedagang di Pasar Badung. Pelaksanaan penelitian dimulai dari bulan Mei sampai bulan Desember 2024. Jenis rancangan penelitian yang digunakan oleh peneliti adalah penelitian observasional seperti penelitian deskriptif dan penelitian cross-sectional analitik. Populasi penelitian meliputi pedagang di area Pasar Badung dengan total sampel penelitian sebesar 70 orang dan teknik pengambilan sampel penelitian melalui purposive sampling. Peneliti mengumpulkan data penelitian secara offline melalui kuesioner dan wawancara. Hasil penelitian melalui uji kendall’s tau-b menyatakan variabel pengetahuan dan variabel tindakan pencegahan primer memiliki nilai r hitung sebesar 0,734 sehingga nilai r hitung > nilai r tabel atau nilai 0,734 > nilai 0,2352. Nilai r hitung lebih besar dibandingkan dengan nilai r tabel mengakibatkan peneliti dapat menciptakan kesimpulan dalam bentuk ada hubungan antara pengetahuan dengan tindakan pencegahan primer mengenai filariasis limfatik pada pedagang di Pasar Badung.
Co-Authors Adiputra, I Komang Hotra Ariwati, Luh Cokorda Agung Wahyu Purnamasidhi Dewa Ayu Agus Sri Laksemi Dyatmika, I Nyoman Adidana Jaya Fitri N, Moh. Yasin Harisutha, Made Dwiki Pradnyana Hidajati, Sri I Kadek Swastika I Made Sudarmaja Isyaputri, Rahmadany Juniantara, I Kadek Ade kumara, i made bagus bayu Ni Putu Wardani Pandango, Ivana Griselarosa Koni Purantara, Anak Agung Gede Wiweka Winahya Putra, I Putu Bagus Krisna Pramana Putri, Luh Kadek Meilina Putu Ayu Asri Damayanti Sanjiwani, Made Indira Dianti Saraswati Devi, Ni Made Kumbha Mella Sri Laksemi, Dewa Ayu Agus Sukmawati Basuki Suputra, I Wayan Bagus Abiyoga Swastika, I Nengah Raka