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All Journal Community Development Journal: Jurnal Pengabdian Masyarakat Communautaire: Journal of Community Service Medicor : Journal of Health Informatics and Health Policy Sinergi International Journal of Psychology Journal of Health Literacy and Qualitative Research Psychosocia : Journal of Applied Psychology and Social Psychology Jurnal Pendidikan Islam
Hafid Algristian
Universitas Nahdlatul Ulama Surabaya
Religion Humanities Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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Dyspepsia as a Trigger for Sleep Disorders: A Case Study of Gut–Brain Axis Interaction Friska Febrian Damayanti; Hafid Algristian; Marintik Ilahi
Medicor : Journal of Health Informatics and Health Policy Vol. 4 No. 1 (2026): January 2026
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/medicor.v4i1.1139

Abstract

Functional dyspepsia is an upper gastrointestinal complaint without organic abnormalities that may interact with sleep through gut–brain axis mechanisms. We report the case of a 49-year-old woman with persistent insomnia occurring concurrently with epigastric pain for approximately one year. The patient relied on hypnotic medication and experienced early-morning awakenings. Psychiatric, somatic, and psychosocial evaluations indicated that the sleep disturbance was related to dyspeptic complaints. Management included psychoeducation, supportive psychotherapy, and Cognitive Behavioral Therapy for Insomnia (CBT-I), along with dyspepsia therapy (sucralfate and omeprazole) and a spiritual approach according to the patient’s preferences. Following integrated therapy, sleep patterns improved and the Insomnia Severity Index score decreased in parallel with the resolution of dyspepsia symptoms. This case demonstrates that dyspepsia can trigger sleep disturbances through gut–brain axis mechanisms and highlights the importance of a multidisciplinary approach in managing insomnia with gastrointestinal comorbidity. The report also emphasizes the clinical relevance of addressing biopsychosocial factors and incorporating culturally sensitive, patient-centered care to enhance therapeutic outcomes and prevent symptom recurrence.
Anxiolytic and Antidepressant Properties of Alprazolam in Generalized Anxiety Disorder: A Systematic Literature Review Afira Febriani Surya Wijaya; Hafid Algristian; Ariyani Sri Suwarti
Medicor : Journal of Health Informatics and Health Policy Vol. 4 No. 2 (2026): April 2026
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/medicor.v4i2.1174

Abstract

Generalized Anxiety Disorder (GAD) is a highly persistent condition characterized by excessive worry, impaired functioning, and frequent comorbidity with depressive symptoms. Although first-line treatments such as SSRIs and SNRIs are effective, their delayed therapeutic onset and early-treatment anxiogenic effects often lead to poor adherence and treatment discontinuation. This systematic review evaluates the short-term efficacy, safety, and neurobiological mechanisms of alprazolam as a rapid-acting therapeutic option for adults with GAD. Eight studies published between 2011 and 2024—comprising randomized trials, systematic reviews, cohort studies, and neuroimaging investigations—met inclusion criteria. Across clinical trials, alprazolam demonstrated consistent and clinically meaningful reductions in anxiety symptoms within days of initiation, supporting its role as a fast-onset anxiolytic agent. Neurobiological findings showed decreased amygdala hyper reactivity and enhanced prefrontal regulatory activity following alprazolam administration, suggesting mechanisms that align with its rapid clinical effects and potential secondary mood benefits. Adverse events were generally mild, including sedation and psychomotor slowing, and withdrawal symptoms were uncommon when alprazolam was prescribed short-term with supervised tapering. However, the evidence base remains limited by short follow-up periods, small mechanistic samples, and a lack of robust long-term comparative studies. Overall, the findings indicate that alprazolam may serve as a useful short-term adjunct during periods requiring rapid symptom stabilization, particularly when initiating antidepressant therapy. Further research is needed to clarify its long-term safety, functional outcomes, and optimal integration into contemporary treatment pathways.
Longitudinal Diagnostic Reassessment of Schizoaffective Disorder in Chronic Psychosis: A Case Report Tegar Narindra Putra; Hafid Algristian; Miftakhul Huda
Medicor : Journal of Health Informatics and Health Policy Vol. 4 No. 2 (2026): April 2026
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/medicor.v4i2.1364

Abstract

Differentiating schizophrenia from schizoaffective disorder remains a significant diagnostic challenge due to substantial symptom overlap and reliance on cross-sectional assessment. This case illustrates how systematic longitudinal reconstruction of mood symptom trajectories supported diagnostic revision after prolonged treatment under an initial schizophrenia diagnosis. A descriptive clinical case approach was employed, involving comprehensive patient interview, collateral family interview, longitudinal symptom mapping, and reassessment based on DSM-5-TR criteria. The patient was a 33-year-old woman with a 13-year history of chronic psychosis initially diagnosed as paranoid schizophrenia. Retrospective reconstruction identified five recurrent major depressive episodes lasting approximately 6–12 months each, accounting for an estimated 6–7 years of the illness course. In addition, at least one documented period of persistent psychosis lasting more than two weeks occurred in the absence of mood symptoms, fulfilling DSM-5-TR criteria for schizoaffective disorder, depressive type. Following diagnostic revision, antidepressant augmentation and structured psychosocial intervention were initiated. At three-month follow-up, depressive symptoms decreased, passive suicidal ideation resolved, and functional status improved as measured by the Personal and Social Performance (PSP) scale (from 40 to 60), with no rehospitalization. This case underscores the importance of longitudinal assessment in chronic psychosis and highlights its implications for diagnostic accuracy and treatment planning.
A Case Report: Post-Traumatic Stress Disorder (PTSD) with Thyrotoxicosis and Psychosocial Stress Masyita Kusuma Maharani; Hafid Algristian; Ariyani Sri Suwarti
Sinergi International Journal of Psychology Vol. 4 No. 1 (2026): February 2026
Publisher : Yayasan Sinergi Kawula Muda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61194/psychology.v4i1.872

Abstract

Post-Traumatic Stress Disorder (PTSD) is a psychiatric condition triggered by trauma, often exacerbated by medical comorbidities like thyrotoxicosis. This report aims to illustrate the complex interaction between PTSD, endocrine dysfunction, and psychosocial stress, highlighting the need for an integrated treatment approach. This case report is based on a clinical case of a 31-year-old female with PTSD and comorbid thyrotoxicosis treated at a hospital in Indonesia. Data were collected through clinical history, physical and psychiatric examinations, and a review of relevant literature. The patient developed PTSD symptoms following a motorcycle accident, including nightmares, hyperarousal, insomnia, and avoidance behavior. Her pre-existing thyrotoxicosis amplified anxiety and physiological arousal, while psychosocial stressors such as legal issues and unemployment perpetuated her symptoms. A combined treatment of Sertraline 50 mg/day, short-term Alprazolam, trauma-focused therapy, and spiritual coping strategies resulted in initial improvement in anxiety and emotional regulation. Managing PTSD with comorbid thyrotoxicosis and psychosocial stress requires a biopsychosocial-endocrine approach. Coordinated pharmacological, psychotherapeutic, and psychosocial interventions are essential for symptom control and functional recovery. This case underscores the importance of multidisciplinary collaboration in complex PTSD presentations.
The Psychosomatic Cycle of Generalized Anxiety Disorder and Chronic Illness: A Clinical Review Amalia Tauziah; Hafid Algristian; Asikah
Journal of Health Literacy and Qualitative Research Vol. 6 No. 1 (2026): March 2026
Publisher : Yayasan Sinergi Kawula Muda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61194/jhlqr.v6i1.981

Abstract

Generalized Anxiety Disorder (GAD) frequently coexists with chronic medical illnesses, creating a complex interaction that may intensify psychological distress and the perception of physical symptoms. This case report describes a 62-year-old male with GAD and multiple chronic comorbidities, including atherosclerotic heart disease, hypertension, type 2 diabetes mellitus with nephropathy, and benign prostatic hyperplasia. The patient presented with persistent health-related worry, sleep disturbance, and heightened preoccupation with bodily sensations, accompanied by moderate impairment in quality of life. Clinical assessment and psychological screening indicated significant anxiety symptoms without prominent depressive features. Based on clinical observations and integration with the biopsychosocial framework, somatosensory amplification, body hypervigilance, and difficulties in emotional expression were hypothesized to contribute to a psychosomatic interaction pattern. These processes may contribute to a reinforcing psychosomatic cycle in which anxiety intensifies the perception of physical symptoms, while chronic illness functions as a persistent internal stressor that maintains health-related worry. These mechanisms were not directly measured using standardized instruments but were inferred from behavioral patterns, illness narratives, and longitudinal clinical documentation. This case highlights how psychological and medical factors may mutually reinforce each other in elderly patients with multimorbidity. An integrative management approach combining pharmacological treatment, psychoeducation, and supportive psychotherapy may help interrupt this reciprocal cycle and improve functional outcomes and quality of life.
The Role of Spirituality in Depression : A Case report Anabela Amoret Amsori; Roosyidah; Syahrul Gusnaldi Prawidya; Novanthy Nur Rohmadhani Subagyo; Muhammad Azhari Baihaqi; Embun Kumalaratih; Hafid Algristian
Psychosocia : Journal of Applied Psychology and Social Psychology Vol. 4 No. 1 (2026): January 2026
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/psychosocia.v4i1.1054

Abstract

Depression is a psychological condition characterized by persistent sadness, hopelessness, and loss of interest that affects emotional, cognitive, and behavioral functioning. Spirituality is believed to play a significant role in reducing depressive symptoms by fostering inner harmony, emotional resilience, and a sense of meaning in life. This case report explores the relationship between spirituality and depression in a 44-year-old woman diagnosed with major depressive disorder with psychotic features. The patient continues to experience negative emotions such as pessimism, lack of self-confidence, continuous crying, and feelings of inferiority that began after being dismissed from her job, a traumatic event that deeply affected her psychological state. She also experienced a decline in spiritual beliefs and practices, which was attributed to her father’s overly strict and inconsistent religious upbringing. This case highlights the close relationship between spirituality and mental health, demonstrating that spiritual well-being can serve as a protective factor against depression by enhancing emotional stability, personal resilience, and positive psychological adjustment. The integration of spiritual care into mental health interventions is therefore essential, as it may improve recovery outcomes and enhance the overall quality of life for individuals experiencing depression.
Effectiveness of a Multimodal Therapeutic Approach for Disorganization Symptoms in Hebephrenic Schizophrenia: A Case Report Affan Tsaqif Taufiqurrahman; Winaryani Winaryani; Hafid Algristian
Psychosocia : Journal of Applied Psychology and Social Psychology Vol. 4 No. 1 (2026): January 2026
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/psychosocia.v4i1.1160

Abstract

Hebephrenic schizophrenia, or disorganized-type schizophrenia, represents one of the most disabling and treatment-resistant subtypes of psychotic disorders, marked by disorganized thinking, affect, and behavior. These symptoms often persist despite standard pharmacological treatment and are associated with poor cognitive and social functioning. This case report explores the effectiveness of an integrated multimodal therapeutic approach that combines pharmacological, cognitive-behavioral, and metabolic strategies in managing a young woman with chronic hebephrenic schizophrenia. The patient, a 23-year-old female with a six-year illness duration and history of medication nonadherence, was treated with aripiprazole 15 mg/day (dopamine D2 partial agonist), trifluoperazine 5 mg/day (full D2 antagonist), folic acid 1 mg/day, and vitamin B6 100 mg/day. Cognitive Behavioral Therapy (CBT) and family psychoeducation were conducted twice weekly for three weeks. After treatment, she demonstrated measurable improvement, including a 1-point reduction in conceptual disorganization and a 2-point improvement in blunted affect (PANSS-R), alongside qualitative gains in coping with auditory hallucinations and affective responsiveness. These results suggest that synergistic modulation of dopaminergic circuits, cognitive restructuring, and metabolic support may yield short-term benefits for patients with treatment-resistant disorganization symptoms. Further longitudinal studies are warranted to evaluate long-term outcomes and neurobiological mechanisms.
Holistic Management of Depressive-Type Schizoaffective Disorder: A Case Illustration Muh Azka Aldani Fadhlurahman; Hafid Algristian; Yekti Mumpuni
Psychosocia : Journal of Applied Psychology and Social Psychology Vol. 4 No. 2 (2026): April 2026
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/psychosocia.v4i2.1359

Abstract

Schizoaffective disorder is a complex psychiatric condition characterized by the coexistence of psychotic and mood symptoms, often requiring comprehensive and long-term management. Achieving sustained clinical stability in depressive-type schizoaffective disorder remains challenging, particularly when psychosocial stressors and limited support systems are present. This case illustration describes a holistic management approach integrating pharmacological treatment, structured family involvement, and patient-centered spiritual coping within an Indonesian cultural context. We present the case of a 44-year-old female diagnosed with depressive-type schizoaffective disorder based on the Indonesian Guidelines for the Classification and Diagnosis of Mental Disorders, corresponding to international diagnostic principles. Clinical data were obtained through psychiatric interviews, longitudinal clinical observation, and review of medical records. The intervention consisted of combined antipsychotic and antidepressant pharmacotherapy, accompanied by structured family support and ethically integrated spiritual coping strategies aligned with the patient’s preferences. Over the course of follow-up, the patient demonstrated a reduction in psychotic symptoms (notably ideas of reference) and depressive features, alongside improvements in sleep patterns, self-care, treatment adherence, and emotional regulation. Functional gains were observed in daily activities and engagement with meaningful roles, with no acute relapse reported during the observed follow-up period. Family involvement contributed to adherence monitoring and stress reduction, while spiritual coping functioned as an internal resource for meaning-making and resilience rather than as a standalone intervention. This case illustrates that a holistic management strategy addressing biological, psychosocial, and spiritual dimensions may support clinical stabilization and functional recovery in depressive-type schizoaffective disorder. While findings from a single case cannot be generalized, this report highlights the potential clinical value of integrating family support and patient-centered spirituality into routine psychiatric care within culturally relevant settings.
The Role of Rumination as a Maladaptive Coping Mechanism in Cases of Comprehensive Anxiety Disorder Osya Azifa Firlani; Hafid Algristian; Budi Cahyono
Psychosocia : Journal of Applied Psychology and Social Psychology Vol. 4 No. 2 (2026): April 2026
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/psychosocia.v4i2.1376

Abstract

Generalized Anxiety Disorder (GAD) is characterized by excessive and persistent worry accompanied by somatic and cognitive symptoms that impair daily functioning. Although rumination has been widely discussed as a form of repetitive negative thinking, its role as a maladaptive coping mechanism sustaining GAD relapse in the context of occupational stress and shift work remains underexplored. This study presents an analytical descriptive case study integrated with a narrative literature review to examine how rumination contributes to symptom maintenance and relapse in GAD. The case involves a 43-year-old female outpatient evaluated at a psychiatric clinic in Surabaya in 2025. The recurrence of anxiety symptoms was precipitated by an early-retirement offer and rotating shift work, which triggered persistent rumination about financial uncertainty. This cognitive process led to insomnia, concentration difficulties, and inconsistent medication adherence, ultimately resulting in symptom relapse. Literature-based interpretation suggests that intolerance of uncertainty (IU) increases vulnerability to rumination, which sustains autonomic hyperarousal and sleep disturbance, while shift work disrupts circadian rhythms and contributes to inconsistent dosing and fluctuating plasma levels of pharmacotherapy. This case highlights a clinically relevant pathway linking occupational uncertainty, rumination, insomnia, and nonadherence in GAD relapse. Comprehensive management should integrate pharmacotherapy, rumination-focused psychotherapy (e.g., CBT or MCT), adherence education, and consideration of workplace-related stressors to reduce recurrence risk.
Co-Authors Affan Tsaqif Taufiqurrahman Afira Febriani Surya Wijaya Aldillah Esa Fitri Amalia Tauziah Amelia Citra Wardani Anabela Amoret Amsori Anabela Amoreth Amsori Andikawati Fitriasari Anna Purnamasari Sugijanti Anna Purnamasari Sugijanti Ariyani Sri Suwarti Ariyani Sri Suwarti Asikah Bambang Edi Suwito Budi Cahyono Chuma Mohamed Muhibu Diana Arum Lisnawati Diyani Shafira Brylyani Eksalanti Aulia Nashira Embun Kumalaratih Fifi Khoirul Fitriyah Firdaus Firdaus Friska Febrian Damayanti Heris Santy, Wesiana Hidaayah, Nur Iskandar Kamariyah, Nurul Ken Putri Raudhatul Jannah Khadijah Khairul Bariyah Khamida Khamida Khuzaimah Nur Juhanifah Rihhadatulays Lini Delina M. Idham Cholid Maki Zamzam Marintik Ilahi Masyita Kusuma Maharani Maulani Putri Ramadhani Mega Astri Miftakhul Huda Misbakhul Munir Muh Azka Aldani Fadhlurahman Muhammad Azhari Baihaqi Novanthy Nur Rohmadhani Subagyo Novera Herdiani, Novera Nur Azizah A. S Nurjanah, Siti - Osya Azifa Firlani Qilmi Faradila Radiani Rahmadaniar Aditya Putri Rika Hardiyanti Hanifa Roosyidah Salvia Adzania Widya Azzuhri Siti Nur Hasina Syahrul Gusnaldi Prawidya Tegar Narindra Putra Tri Deviasari Wulan Tutik Nur Kasiani Winaryani Winaryani Yekti Mumpuni Yulia Anggraeni Zafira Aliya Shafwa Putri Chambali Zainul Hadi Wildan Ismail