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All Journal e-CliniC JURNAL BIOMEDIK Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Sehat Indonesia (JUSINDO)
Jimmy Panelewen, Jimmy
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Profil kasus batu empedu di RSUP Prof. Dr. R. D. Kandou Manado periode Oktober 2015-Oktober 2016 Tuuk, Andreyne L.Z.; Panelewen, Jimmy; Noersasongko, A. Djarot
e-CliniC Vol 4, No 2 (2016): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v4i2.14454

Abstract

Abstract: Gallstones are solid materials or crystals formed in gallbladder, common bile duct, or in both. Gallstones constitute a significant health problem in developed countries. Epidemiologic studies showed that increasing age was associated with increasing prevalence of gallstones. This study was aimed to obtain the profile of gallstone cases at Prof. Dr. R. D. Kandou Hospital from October 2015 to October 2016. This was a retrospective descriptive study. The results showed that there were 113 cases of gallstones. The majority of cases were females, age group 60 years, serum bilirubin ≥3 mg/dl associated with apparent jaundice, and treated with surgery using cholecystectomy laparotomy and cholecystectomy laparoscopy techniques.Keywords: gallstone, profile Abstrak: Batu empedu adalah material atau kristal yang terbentuk dalam di dalam kandung empedu, saluran empedu, atau keduanya. Batu empedu merupakan masalah kesehatan yang signifikan dalam masyarakat berkembang. Studi epidemiologi menunjukkan bahwa prevalensi batu empedu berkaitan dengan meningkatnya usia dan lebih sering ditemukan pada perempuan. Penelitian ini bertujuan untuk mengetahui profil pasien batu empedu di RSUP Prof. Dr. R. D. Kandou Manado dalam periode Oktober 2015 - October 2016. Jenis penelitian ialah deskriptif retrospektif. Hasil penelitian mendapatkan 113 kasus penyakit batu empedu, Majoritas kasus ialah perempuoan, kelompok usia 60 tahun, kadar bilirubin ≥3 mg/dl disertai ikterik yang jelas, dengan penanganan operatif kolesistektomi laparatomi dan kolesistektomi laparoskopik. Kata kunci: batu empedu, profil
Rasio Neutrofil Limfosit sebagai Prediktor Kejadian Kebocoran Anastomosis pada Pasien Kanker Kolorektal Panelewen, Jimmy; Tendean, Michael; Langi, Fima; Akmal, Nuzly Q.
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58246

Abstract

Abstract: Anastomotic leakage is a serious complication following colorectal cancer resection that can increase morbidity and mortality. This study aimed to analyze the potential of the neutrophil-lymphocyte ratio (NLR) as a predictor of anastomotic leakage in colorectal cancer patients. This was a retrospective analytical and observational study involving 30 patients who underwent colorectal cancer resection and anastomosis at Prof. Dr. R. D. Kandou Hospital in Manado. The NLR values were analyzed preoperatively and on the first (D+1), third (D+3), fifth (D+5), and seventh (D+7) postoperative days. The results showed significant differences in NLR values between leakage and non-leakage groups across all phases (p<0.001). The receiver operating characteristic (ROC) curve analysis yielded optimal NLR cut-offs for leakage prediction: preoperative >2.1150, D+1 >3.4750, D+3 >2.7650, D+5 >3.0200, and D+7 >3.2850, with sensitivity and specificity reaching 100% in several phases. In conclusion, neutrophil-lymphocyte ratio has a potential as an accurate predictor of anastomotic leakage, enabling early detection and improved risk management. Further research with larger samples is needed to validate these findings and explore their clinical applications. Keywords: neutrophil-lymphocyte ratio; anastomotic leakage; colorectal cancer    Abstrak: Kebocoran anastomosis merupakan komplikasi serius pasca reseksi kanker kolorektal yang dapat meningkatkan morbiditas dan mortalitas. Penelitian ini bertujuan menganalisis potensi rasio neutrofil limfosit (RNL) sebagai prediktor kejadian kebocoran anastomosis pada pasien kanker kolorektal. Penelitian ini menggunakan metode observasional analitik retrospektif, melibatkan 30 pasien yang menjalani reseksi dan anastomosis kanker kolorektal di RSUP Prof. Dr. R. D. Kandou Manado. Nilai RNL dianalisis pada fase preoperatif, hari pertama (H+1), ketiga (H+3), kelima (H+5), dan ketujuh (H+7) pasca operasi. Hasil penelitian memperlihatkan perbedaan bermakna nilai RNL antara kelompok kebocoran dan tanpa kebocoran pada semua fase (p<0,001). Analisis kurva ROC menghasilkan cut-off optimal RNL untuk prediksi kebocoran: preoperatif >2,1150, H+1 >3,4750, H+3 >2,7650, H+5 >3,0200, dan H+7 >3,2850, dengan sensitivitas dan spesifisitas mencapai 100% pada beberapa fase. Simpulan penelitian ini ialah rasio neutrofil limfosit memiliki potensi sebagai prediktor yang akurat untuk kebocoran anastomosis, serta memungkinkan deteksi dini dan manajemen risiko yang lebih baik. Penelitian lebih lanjut dengan sampel yang lebih besar diperlukan untuk memvalidasi temuan ini dan mengeksplorasi aplikasi klinisnya. Kata kunci: rasio neutrofil limfosit; kebocoran anastomosis; kanker kolorektal
Delayed Staged Hepatectomy for Metastatic Colorectal Cancer: A Single Case Report Tendean, Michael; Paparang, Steven; Tjandra, Ferdinand; Mambu, Toar; Panelewen, Jimmy; Salem, Billy
e-CliniC Vol. 13 No. 2 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i2.59701

Abstract

Abstract: Liver metastases are common in patients with colorectal cancer; almost 70% will develop liver metastases during the course. The recommended treatment for colorectal liver metastasis (CRLM) is multidisciplinary, including liver resection and chemotherapy. We reported a 52-year-old female with stage 3B distal third rectal adenocarcinoma which eight months earlier underwent Mile’s procedure plus total mesorectal excision (TME) followed by adjuvant radiotherapy (50gy). During surveillance, liver metastases was found at segments 4B-5. A delayed anatomical staged hepatectomy segments 4B-5 was performed. Intraoperative USG findings suggested liver metastases at segments 7, 8, and 3, and non-anatomical liver resection was performed in accordance with parenchymal liver sparing principles. No post-hepatectomy liver failure (PHLF) was detected, but billoma occured at 1-month post hepatectomy. USG guided percutaneous drainage was performed to resolve the billoma. Colorectal metastasis (CRLM) was detected at six months post-hepatectomy, and the patient underwent adjuvant chemotherapy with improvement in survival rate. In conclusion, delayed staged hepatectomy for CRLM is a safe and beneficial procedure, though there is still no guideline regarding the sequence of resection. Keywords: hepatectomy; colorectal metastasis; billoma; colorectal cancer
Co-Authors Akmal, Nuzly Akmal, Nuzly Q. Ayawaila, Marven Billy Salem Erwin . Heber B. Sapan, Heber B. Ishak Lahunduitan, Ishak Kaunang, Maria Langi, Fima Laurens T. B. Kalesaran, Laurens T. B. Luciana, Fanni Mambu, Toar Mambu, Toar D B Mambu, Toar DB Noersasongko, A. Djarot Paparang, Steven Salem, Billy E. Ch.R. Tendean, Michael Tjandra, Ferdinand Tuuk, Andreyne L.Z. Verro Ratuwalangon, Verro Yenzher C. Tamuntuan, Yenzher C. Yuansun Khosama, Yuansun