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Injected citicoline improves impairment and disability during acute phase treatment in ischemic stroke patients Wahyudi, Rino; Hasmono, Didik; Fitrina, Ruhaya; Armal, Khairil
Folia Medica Indonesiana Vol. 51, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

Treatment strategy of ischemic stroke is to reduce the extent of the damage and rescue neurons from death in the early days of ischemic events. Recombinant Tissue-Plasminogen Activator (r-TPA) is the only recommended therapy, but their use is very limited. Citicoline is a neuroprotectant with a therapeutic effect on several stages of the ischemic cascade. However, its use is still being debated. The purpose of this study was to analyze the use of supplementation citicoline injection in patients with acute ischemic stroke in relations to differences in changes in the level of interference (impairment), rate limitation (disability) and the level of obstruction (handicap) between the group receiving supplementation of citicoline injection 2x500 mg iv and the group without supplementation during acute phase treatment. This study was a prospective cohort study using experimental design in patients with acute ischemic stroke who met the inclusion and exclusion criteria with or without supplementation citicoline between January - April 2015 in the National Stroke Hospital, Bukittinggi. Rate of interference was assessed with NIHSS, level of limitations with Barthel Index, and level of obstruction with modified Rankin Scale. Assessment was done 2 times, before and after the treatment. Statistical methods used in this study were Wilcoxon signed rank test, paired T-test and Mann-Whitney test. This study was conducted on 50 subjects divided into 2 groups, a control group without supplementation and group treated with injected citicoline of 2x500 mg iv. Demographic and baseline characteristics did not differ between groups. There were differences in level of interference changes. Mean decrease in control group was 0.96 ± 1.74 NIHSS, while that in treatment group was 2.84 ± 1.46 NIHSS (p <0.05). There were differences in changes in the level of limitations. Mean increase of Barthel Index in control group 9.60 ± 11.17 and in treatment group 20.40 ± 13.99 (p <0.05). However, changes in the level obstacle showed no difference. In conclusion, citicoline injection supplementation in patients with ischemic stroke during acute phase treatment showed improvement differences in changes in the level of distraction (impairment) and the rate limitations (disability), but showed no difference in changes in the level of obstruction (handycaps).
Pelatihan Penguatan Kapasitas Pedagogi Literasi Spasial Guru Geografi Menggunakan Pendekatan OPTIC-SCRAP Susetyo, Bigharta Bekti; Caesario, Dipo; Luthfi, Zaky Farid; Edial, Helfia; Wahyudi, Rino; Marlina, Gita
ABDI: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 8 No 1 (2026): Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Labor Jurusan Sosiologi, Fakultas Ilmu Sosial, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/abdi.v8i1.1809

Abstract

Pendidikan geografi pada materi litosfer memerlukan alat bantu deskriptif seperti peta yang dapat dielaborasi dengan teknologi geospasial. Namun, pada pelaksanaannya peserta didik masih mengartikan alat bantu tersebut hanya sebagai simbol visual-spasial, mengabaikan informasi analisis spasial komprehensif lain yang lebih dalam. Temuan lain di lapangan juga mengarah pada adanya ketergantungan pada hafalan, sedangkan geografi membutuhkan penalaran kritis, analitis, dan sistematis, terutama dalam mengevaluasi fitur-fitur yang digambarkan pada peta. Di sisi lain, guru diharapkan mengelaborasi dengan deep learning untuk pemrosesan informasi materi pembelajaran geografi secara utuh. Tujuan dari pengabdian ini untuk penguatan kapasitas pedagogi guru dalam mengembangkan keterampilan literasi dan analisis spasial geografi peserta didik. Metode pengabdian menggunakan pelatihan partisipatif (participatory action research) dengan guru yang aktif melakukan kegiatan pelatihan dengan tahapan planning (persiapan), taking action-observation (pelaksanaan) dan reflection-evaluation (refleksi-evaluasi). Hasil pengabdian menunjukkan bahwa literasi spasial guru meningkat dengan nilai N-Gain 0,64 (sedang). Pada aktivitas pembelajaran, guru dapat mengembangkan soal berbasis literasi spasial OPTIC-SCRAP, serta guru dapat merancang dan mengembangkan aktivitas pembelajaran kelas secara interaktif menggunakan sumber data spasial, yakni peta geologi. Implikasi dari kegiatan yang sudah dilakukan, pelatihan literasi spasial berbasis OPTIC-SCRAP membantu guru memanfaatkan alat bantu deskriptif geografi, yang membuat pembelajaran semakin kontekstual dan relevan dengan perkembangan teknologi, khususnya teknologi geospasial dengan analisis citra dan peta.