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Sintesis Khalkon dan Uji Aktivitas Tabir Surya Secara In Vitro Dewi Darmiyani Napu
Indonesian Journal of Pharmaceutical Education Vol 2, No 3 (2022): September-Desember 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i3.19326

Abstract

Synthesis of 2’,4’-dihydroxy-3,4-dimethoxychalcone and in vitro test of its sunscreen activity have been carried out. Chalcone was synthesized from 3,4-dimethoxybenzaldehyde and 2,4-dihydroxyacetophenone through Claisen-Schmidt condensation. The synthesis was performed by using KOH 40% under stirring at room temperature for 48 h. The synthesized compounds was characterized using FTIR, GC-MS and 1H NMR spectrometers. Further, the chalcone were screened for its in vitro sunscreen activity by using UV-Vis spectrophotometer. The result showed that the chalcone has been succesfully synthesized in 36.94% Yield. The activity of invitro test showed the chalcone has SPF values with maximal protection category at the consentration 15 µ/mL produce SPF 9.749
The Impact of Project-Based Flex Blended Learning Model on Critical Thinking Skills of Students in Science Courses Alfian Erwinsyah; Zohrawaty Hiola; Sabrina Nadjib Mohamad; Dewi Darmiyani Napu; Aljunaid Bakari; Asriyati Nadjamuddin; Rinaldi Datunsolang
Jurnal Penelitian Pendidikan IPA Vol 11 No 6 (2025): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i6.11250

Abstract

This study aims to analyze the effectiveness of the Project-Based Flex Blended Learning (PjBFBL) model in improving students' critical thinking skills on Ohm's Law material in science courses. The quasi-experimental method uses a Nonequivalent Control Group Design with 41 fourth semester students divided into experimental (PjBFBL) and control (conventional) groups. Instruments include critical thinking tests based on seven indicators (interpretation, analysis, evaluation, inference, explanation, self-regulation, essential questions), analyzed using N-Gain, T-test, and effect size. Results showed the experimental group achieved a moderate N-Gain improvement (0.63) with the highest categories in inference (0.78; high) and explanation (0.73; high), while the control group only had a low N-Gain (0.28). The independent T-test confirmed the significant difference (t (25,092) = 7.230; p<0.05) with an average difference of 35.78% and a large effect size (Cohen's d=2.299). The research conclusion indicates that the PjBFBL model effectively improves critical thinking skills, particularly in multidimensional reasoning and information synthesis, through the integration of authentic projects, hybrid flexibility, and structured collaboration. The findings recommend the adoption of this model in science learning to bridge the 21st century competency gap, noting the need to strengthen the interpretation aspect through more contextualized instruments