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All Journal Jurnal Kesehatan: Jurnal Ilmu- Ilmu Keperawatan, Kebidanan, Farmasi dan Analis Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian GENIUS JOURNAL (General Nursing Science Journal) Pharmacy Genius KIAN Journal Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian
Siti Rahmah Kurnia Ramdan
STIKes Muhammadiyah Ciamis
Chemistry Education Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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FORMULASI DAN NILAI SPF KRIM TABIR SURYA KOMBINASI EKSTRAK PEGAGAN ( Centella asiatica L) DENGAN TiO2: FORMULATION AND SPF VALUE SUNSCREEN CREAM COMBINATION GOTU KOLA EXTRACT ( Centella asiatica L) WITH TiO2 Siti Rahmah Kurnia Ramdan; Desi Purwanti; Nia Kurniasih; Nurhidayati Harun
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.302

Abstract

Pegagan (Centella Asiatica L.) merupakan herba yang memiliki banyak manfaat untukkesehatan dan kecantikan kulit. Saat ini ekstrak pegagan banyak digunakan sebagai bahanaktif dalam bebagai sediaan kosmetik karena memiliki kemampuan untuk menghidrasi kulit,sebagai antioksidan, mencerahkan kulit, dan mengurangi efek radiasi sinar matahari. Ekstrakpegagan mengandung senyawa terpenoid, alkaloid, flavonoid, saponin dan tannin, Penelitianini bertujuan untuk mengetahui pengaruh konsentrasi ekstrak pegagan 2%, 4% dan 8%terhadap nilai Sun Protecting Factor ( SPF) pada sediaan krim tabir surya dengan titaniumdioksida 1,5% sebagai uv filter. Efektivitas sediaan dilakukan berdasarkan pengukuran nilaiabsorbansi dengan menggunakan spektrofotometer UV-Vis pada rentang panjanggelombang 290-320 nm, selanjutnya nilai SPF dihitung menggunakan persamaan Mansur.Sediaan krim tabir surya dibuat tiga formulasi berdasarkan perbandingan konsentrasi ekstrakpegagan dengan titanium dioksida yaitu Kontrol negatif (F0) 0%:1,5%, Formulasi I (FI)2%:1,5%, Formulasi II (F2) 4%: 1,5% dan Formulasi III (F3) 8%:1,5%. Selanjutnyadilakukan evaluasi berupa uji organoleptik, uji homogenitas, uji pH, uji daya sebar, uji dayalekat dan uji viskositas serta pengukuran nilai SPF. Hasil pengujian menunjukan bahwaketiga formulasi krim tabir surya ekstrak pegagan memenuhi standar uji dengan nilai SPFmasing-masing yaitu F0 1,569 memiliki efek proteksi minimal, FI 3,263 memiliki efekproteksi minimal, F2 5,669 memiliki efek proteksi sedang, dan F3 8,904 memiliki efekproteksi maksimal.Kata kunci : Pegagan, SPF, Titanium dioksida.
Penetapan Kadar Antosianin Ekstrak Etanol Bunga Telang (Clitoria ternatea) dengan Metode Differensial pH Ramdan, Siti Rahmah Kurnia; Alviansyah, Aldi
Pharmacogenius Journal Vol 3 No 1 (2024): Pharmacy Genius
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/pharmgen.v3i01.306

Abstract

Pendahuluan: Antosianin merupakan keluarga besar polifenol yang menunjukkan pigmen  pada berbagai jenis  buah-buahan dan tanaman di alam. Pigmen yang ditunjukkan yaitu merah, merah jambu, biru dan ungu. Antosianin bertanggung jawab terhadap adanya warna biru dari bunga telang. Berbagai manfaat yang dimiliki antosianin bagi kesehatan diantaranya sebagai proteksi DNA, antiinflamasi, anti kanker, antioksidan, antidiabetes, mencegah penyakit kardiovaskular dan penyakit neurodegeneratif. Tujuan: Penelitian ini bertujuan untuk menentukan kadar antosianin pada ekstrak etanol bunga telang. Metode: Penentuan kadar antosianin pada ekstrak etanol  bunga telang dilakukan dengan metode differensial pH dengan menggunakan spektrofotometri uv-vis pada panjang gelombang 510 nm dan 700 nm. Hasil: Kadar antosianin pada ekstrak etanol bunga telang yang dilakukan pada penelitian ini dengan metode differensial pH diperoleh sebesar 0,853%. Kesimpulan: Dari hasil penelitian dapat disimpulkan bahwa kadar antosianin bunga telang dari hasil ekstraksi maserasi dengan  pelarut etanol 70% cukup tinggi dan berpotensi sebagai salah satu sumber obat bahan alam dan sebagai pewarna alami.
Uji Aktivitas Antioksidan Seduhan Bunga Telang (Clitoria ternatea L) Dengan Metode DPPH Ramdan, Siti Rahmah Kurnia
Pharmacogenius Journal Vol 3 No 1 (2024): Pharmacy Genius
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/pharmgen.v3i01.328

Abstract

ABSTRAK   Pendahuluan: Bunga telang (Clitoria ternatea L.) merupakan tanaman yang memiliki pigmen ungu yang mencolok. Warna ungu dari tanaman ini disebabkan karena adanya kandungan antosianin yang dikenal aktivitas antioksidaanya yang sangat baik.  Minuman sari bunga telang dapat dibuat dengan cara penyeduhan pada suhu tertentu. Aktivitas antioksidan dari dekokta bunga telang dapat diketahui dengan berbagai metode diantaranya menggunakan  metode DPPH (2.2 diphenyl-1-picrylhydrazil). Tujuan: Tujuan dari penelitian ini untuk mengetahui aktivitas antioksidan seduhan bunga telang dengan aquades pada suhu 50oC dengan menggunakan metode DPPH. Metode: Penelitian ini dilakukan dengan membuat dekokta bunga telang pada suhu 50oC dengan mengukur daya hambatnya terhadap senyawa DPPH sebagai radikal bebas yang ditunjukkan oleh nilai absorbansi dari hasil rekasi dibandingkan dengan larutan kontrol dengan menggunakan Spektrofotometri UV-Vis pada panjang gelombang 400-800 nm. Hasil: Hasil penelitian ini berupa nilai absorbansi dan persen penghambatan dekokta bunga telang terhadap senyawa DPPH, aktivitas antioksidan ditunjukkan oleh nilai IC50 yaitu konsentrasi yang yang mampu menghambat 50% radikal bebas.  Dari hasil penelitian diperoleh bahwa aktivitas antioksidan dekokta bunga telang pada suhu 50oC memiliki aktivitas sedang. Kesimpulan: Dari data penelitian dapat disimpulkan bahwa dekokta bunga telang memiliki aktivitas antioksidan sedang yang sangat baik untuk dimanfaatkan sebagai minuman kesehatan.
OPTIMIZATION OF GELATIN CONCENTRATION IN TABLET WITH AFRICAN LEAF EXTRACT (Vernonia Amygdalina) Wahlanto, Panji; Yusuf, Anna L; Nugraha, Davit; Siti Rahmah KR; Dissya Alifia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1614

Abstract

African plants, especially the leaves, are a type of medicinal plant used by the community. This African leaf contains active lavonoids that can be used to measure blood glucose levels. Tablet preparations have the advantage that they are easy to consume, so in this study African leaves (Vernonia Amygdalina) were made into tablets. The ratios of the binder used were 4%, 5%, and 6%. After obtaining the evaluation results, data analysis was performed using the Kruskal–Wallis SPSS statistical test with a confidence level of 95%. The evaluation results showed that the three formulations only fulfilled the respective requirements, namely for the angle of repose test between 16.6° - 21.3°, the granule thickening test of all formulations is below <20% and meets the requirements, the weight uniformity test has an average of 191-192 mg meeting the predetermined requirements, namely not more than 3 times with an average of 7.35 -7.36 mm and a thickness of mean +  SD 0,47  the disintegration time test of all formulations stated that they met the requirements that had been determined that is not more than 15 minutes, the friability test only on formulation III which met the requirements to get a result of 0.54% in formulations I and II did not meet the specified requirements, the hardness test of all formulations did not meet the specified test requirements.  Keywords: African leaf extract, gelatin, tablets.
Utilization of Purple Sweet Potato Juice As an Alternative Violet Crystal in Coloring Streptococcus sp Bacteria and Escherichia coli Ruhimat, Undang; Mutmainah, Rahayu Nirmatul; Ramdan, Siti Rahmah Kurnia; Firdaus, Nabil Ridla
JURNAL KESEHATAN STIKes MUHAMMADIYAH CIAMIS Vol. 11 No. 2 (2024): Jurnal Kesehatan (October 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/jurkes.v11i2.769

Abstract

Gram staining is a staining method used to distinguish bacterial species into two major groups, namely Gram-positive and Gram-negative, Crystal violet is the primary (main) dye that will colour the target microorganisms. Staining in bacteria can be replaced using alternative substances with low cost, readily available and harmless, one of which uses substances that have anthocyanin content, namely purple sweet potato. The purpose of this study was to determine the results of using purple sweet potato as an alternative substance to replace crystal violet in staining Streptococcus sp and Escherichia coli bacteria. The method used is experimental. Based on the results of research that has been done on the use of purple sweet potato juice as an alternative substance to crystal violet in gram staining of Streptococcus sp and Escherichia coli bacteria, it shows that purple sweet potato material can be used at pH 6.5 and 5.7 while at pH 5.5 and 5 the bacteria are not perfectly coloured. So it can be concluded that purple sweet potato juice can be used as an alternative substance to Crystal violet in gram staining.
Hedonic Evaluation of Red Ginger Extract Gummy Candy as an Innovative Approach to Prevent Stunting in Children Under Five Heryani, Heni; Nugraha, Davit; Lestari, Lusi; Rahmah Kurnia, Siti; Yusuf, Anna L
Genius Journal Vol. 5 No. 2 (2024): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v5i2.425

Abstract

Introduction: Stunting can have long-term impacts on children's health and development. Preventing stunting in children under five requires a comprehensive approach, including adequate and balanced nutritional intake. One of the natural ingredients commonly used in traditional medicine is red ginger (Zingiber officinale var. rubrum), which contains phytochemical compounds, vitamins, minerals, and fiber beneficial for maintaining vascular and digestive health. Gummy candy formulations have the advantage of high acceptability and appeal, particularly for children who find it difficult to consume medicine. Objective: This study aims to determine the level of preference for gummy candy made with red ginger extract as a strategy to prevent stunting in children under five. Method: The study employed an experimental design using a sensory hedonic test. The inclusion criteria included mothers with toddlers. A total of 20 participants were selected using an incidental sampling technique. Result: The findings indicated that participants showed a high level of preference for red ginger extract gummy candy. On average, the gummy candy was rated as highly appealing in terms of appearance, taste, aroma, and texture. Conclusion: Red ginger extract gummy candy has significant potential to be well-accepted by children under five. Further improvements are recommended, particularly in enhancing the gummy candy's appearance and incorporating more varied shapes to increase its appeal.
Isolasi dan Identifikasi Kurkumin Ekstrak Etanol Temulawak (Curcuma xanthorriza Roxb.) dengan Metode Kromatografi Kolom Ramdan, Siti Rahmah Kurnia; Asih, Aas Catia; Yusuf, Anna L; Nugraha, Davit; Indriastuti, Marlina; Wahlanto, Panji
Pharmacogenius Journal Vol 3 No 3 (2024): Pharmacy Genius
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/pharmgen.v3i3.427

Abstract

Pendahuluan: Temulawak telah banyak digunakan oleh masyarakat dalam pengobatan tradisional dengan berbagai manfaat. Rimpang temulawak mengandung kurkumin, serat, pati, kalium oksalat, minyak atsiri, flavonoid dan zat-zat tersebut berfungsi sebagai antimikroba, mencegah penggumpalan darah, immunostimulan, anti peradangan, melancarkan metabolisme dan fungsi organ tubuh. Tujuan: Tujuan dari penelitian ini untuk melakukan isolasi kurkumin dari ekstrak etanol 95% temulawak dengan menggunakan kromatografi kolom, kemudian diidentifikasi spektrofotometri UV-Vis pada panjang gelombang 400-800 nm. Metode: Metode penelitian yaitu isolasi kurkumin dengan kromatografi kolom terhadap ekstrak etanol 95% temulawak dengan eluen kloroform:etanol:asam asetat glasial (94:5:1), selanjutnya dilakukan identifikasi dengan spektrofotometri UV-Vis pada panjang gelombang 400nm-800nm. Hasil: Hasil isolasi senyawa kurkumin dari ekstrak temulawak dengan eluen kloroform:etanol:asam asetat glasial (94:5:1) diperoleh dengan menggunakan kromatografi kolom berupa cairan berwarna kuning pekat, kemudian identifikasi dengan spektrofotometri UV Vis dan diperoleh nilai absorbansi tertinggi pada panjang gelombang maksimum 425 nm. Kesimpulan: Dari data tersebut dapat disimpulkan bahwa kurkumin dapat diisolasi dari ekstrak temulawak dengan metode kromatografi kolom dan diidentifikasi dengan Spektrofotometri Uv Vis.
Relationship Between Knowledge and Medication Adherence in Diabetes Mellitus Patients at RSUD Ciamis Siti Rahmah Kurnia Ramdan; Selviana Putri Dewi; Elis Roslianti; Yanti Srinayanti; Rosmiati
JURNAL KESEHATAN STIKes MUHAMMADIYAH CIAMIS Vol. 13 No. 1 (2026): Jurnal Kesehatan
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/jurkes.v13i1.1020

Abstract

Diabetes mellitus is a complex chronic disease requiring continuous medical care with multifactorial risk-reduction strategies beyond glycemic control. Diabetes self-management education and support are essential to prevent acute complications, and diabetes remains a major global health concern. This study aimed to determine the relationship between patient knowledge and adherence to antidiabetic medication among diabetes mellitus patients at Ciamis Regional General Hospital. This study used a quantitative descriptive design to assess the relationship between patient knowledge and medication adherence. The research was conducted in the outpatient department of Ciamis Regional General Hospital. The study population consisted of diabetes mellitus patients receiving treatment during the study period. A total sampling technique was applied, involving 39 respondents. Data were analyzed using statihistic. The statistical analysis using the Chi-square test showed a p-value of 0.008 (p < 0.05), indicating a significant relationship between patient knowledge and adherence to antidiabetic medication. There is a significant association between patient knowledge and adherence to antidiabetic medication among diabetes mellitus patients at Ciamis Regional General Hospital.
Red Ginger Gummy Candy as a Stunting Prevention Strategy in Children Under Five Heni Heryani; Lusi Lestari; Anna Yusuf; Davit Nugraha; Siti Rahmah Kurnia Ramdan
KIAN JOURNAL Vol 5 No 2 (2026): KIAN JOURNAL (September 2026)
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/kian.v5i2.1054

Abstract

Introduction: Stunting is a major public health problem that affects the growth and development of children under five. Functional foods in child-friendly forms may provide an alternative nutritional approach to support linear growth and stunting prevention. Objective: This study aimed to evaluate the potential of red ginger extract gummy candy as a functional food to support linear growth and stunting prevention among children under five. Method: This quasi-experimental study used intervention and control groups. Children in the intervention group received red ginger extract gummy candy, while those in the control group received a placebo for one month. Changes in height and weight were assessed before and after the intervention. Result: The Shapiro–Wilk test showed that the anthropometric data were not normally distributed (p<0.05). In the intervention group, height increased significantly after the intervention (p=0.005), whereas the change in body weight was not statistically significant (p=0.161). In the control group, neither body weight (p=0.138) nor height (p=0.059) showed statistically significant changes. However, the Mann–Whitney U test showed no statistically significant difference between the intervention and control groups in changes in body weight (p=0.970) or height (p=0.701).. Conslusion: Red ginger gummy candy was associated with a significant increase in height within the intervention group, but the change was not significantly different from the control group. Further studies with larger samples and longer interventions are needed to determine its potential in supporting linear growth.
Co-Authors Ade Raina Agus Setiawan Alviansyah, Aldi Anna L Yusuf Anna Yusuf Asih, Aas Catia Ayu Fuji Astuti Davit Nugraha Desi Purwanti Dini Umayati Dissya Alifia Elis Roslianti Faisal Akbar Firdaus, Nabil Ridla Heni Heryani Heni Heryani Indriastuti, Marlina Lusi Lestari Nia Kurniasih Nia Kurniasih Nina Muthoharoh Nurhidayati Harun panji wahlanto Rahayu Nirmatul Mutmainah Resi Lestari Risda Wulandari Rosmiati Selviana Putri Dewi Undang Ruhimat Vivit Fitriah Yanti Srinayanti