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All Journal Medical Journal of Indonesia Sari Pediatri Paediatrica Indonesiana
Wirahmadi, Angga
Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Indonesia Rumah Sakit Cipto Mangunkusumo
Health Professions Medicine & Pharmacology

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Growth and developmental delay risk factors among under-five children in an inner-city slum area Hartono Gunardi; Resyana P. Nugraheni; Annisa R. Yulman; Soedjatmiko Soedjatmiko; Rini Sekartini; Bernie E. Medise; Angga Wirahmadi; Elizabeth Melina
Paediatrica Indonesiana Vol 59 No 5 (2019): September 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (279.872 KB) | DOI: 10.14238/pi59.5.2019.276-83

Abstract

Background Growth and developmental delays are common among children under the age of five years (under-five children), especially in slum areas. Early detection and intervention may give better prognoses. Objective To detect growth and developmental delays and related risk factors among under-five children living in an inner-city slum area of the Indonesian capital. Methods This cross-sectional study was conducted from October to November 2018 in Tanah Tinggi, Johar Baru District, an inner-city slum area in Central Jakarta. Subjects were healthy children aged 3–60 months. Socioeconomic profile was obtained through questionnaires, anthropometric data through measurements, and developmental status through the Kuesioner Pra Skrining Perkembangan (KPSP) instrument. Development was considered to be delayed for KPSP scores <9. Data were analyzed using Chi-square test. Results Of 211 subjects, prevalence of underweight, stunting, and wasting were 35.1%, 28.0%, and 20.9%, respectively, meanwhile low maternal education, and low family income were 57.9% and 75%. The prevalence of developmental delay was 10%, while suspected developmental delay was 26.1%. The prevalence increased from age 21 months and peaked at 36 months. Associated risk factors were low maternal education, low family income, underweight weight-for-age, stunted height-for-age, and microcephalic head circumference-for-age. Conclusion Low education and low income were significant risk factors for growth and developmental delay.
Pengetahuan dan Kepatuhan Remaja Terhadap Implementasi Protokol Kesehatan pada Tahun Kedua Pandemi COVID-19 Bernie Endyarni Medise; Sreshta Mukhi; Angga Wirahmadi; Hartono Gunardi; Soedjatmiko Soedjatmiko
Sari Pediatri Vol 24, No 6 (2023)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp24.6.2023.370-6

Abstract

Latar belakang. Kasus pertama pasien COVID-19 di Indonesia dilaporkan pada bulan Maret 2020. Pemerintah memberlakukan Pembatasan Sosial Berskala Besar termasuk penutupan sekolah tatap muka serta mengeluarkan protokol kesehatan untuk diterapkan oleh masyarakat. Pandemi menyebabkan perubahan besar dalam tatanan kehidupan, kebiasaan dan pola hidup remaja. Tujuan. Penelitian ini ingin melihat pengetahuan dan kepatuhan remaja terhadap implementasi protokol kesehatan pada tahun ke dua pandemi COVID-19.Metode. Penelitian ini menggunakan metode potong lintang menggunakan kuesioner yang diisi secara daring dan dilakukan pada tahun ke dua pandemi COVID-19 dari bulan April hingga Juli 2021. Subjek merupakan remaja usia 10-18 tahun di DKI Jakarta. Pemilihan sekolah dilakukan secara cluster sampling. Hasil. Sebanyak 406 responden dari 20 sekolah mengikuti penelitian. Hanya sekitar 5,42% responden yang menjawab dengan benar cara transmisi SARS-CoV-2 dan hanya 43,84% responden yang menjawab dengan tepat 6 langkah cuci tangan. Sebanyak 45,81% responden memiliki nilai total pengetahuan yang baik (nilai >7). Terdapat tren yang menunjukkan persentase remaja yang mendapatkan skor pengetahuan di atas tujuh lebih banyak pada kelompok remaja dengan nilai kepatuhan yang lebih tinggi.Kesimpulan. Pada tahun ke dua pandemi COVID-19 masih banyak remaja yang kurang pengetahuannya mengenai COVID-19 dan belum menerapkan protokol kesehatan dengan baik.
Mental health problems in children with chronic disease at the pediatric inpatient ward of Dr. Cipto Mangunkusumo Hospital Wangke, Lydia; Medise, Bernie Endyarni; Wirahmadi, Angga; Sekartini, Rini; Gunardi, Hartono; Soedjatmiko, Soedjatmiko
Paediatrica Indonesiana Vol. 65 No. 1 (2025): January 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.1.2025.37-41

Abstract

Background Since the survival of a patient with chronic physical illness has improved, major concerns arise about their quality of life and functioning. Childhood and adolescence are critical periods for promoting mental health because more than half of mental health problems begin at this stage, and many of those mental health problems will persist into adult life. Objective To analyze the risk of mental health problems among children hospitalized with chronic disease. Method An analytic observational study with a cross-sectional design was conducted using secondary data of 754 children aged 4-18 years admitted to the pediatric inpatient ward of Cipto Mangunkusumo Hospital, Jakarta between June 2021 and August 2022. We collected the results of subjects’ mental health screening conducted by the Growth, Development, and Social Pediatrics Division, Department of Child Health, Cipto Mangunkusumo Hospital during the subjects’ admission. Mental health problems evaluated in this study included psychosocial dysfunction screened using the Pediatric Symptom Checklist 17 (PSC-17) and depression screened using the Children’s Depression Inventory (CDI). Results Of the 754 subjects included, 520 (69.0%) were classified as having a chronic disease. The prevalence of psychosocial dysfunction and depression in children with chronic diseases was 19.6% and 6.3%, respectively. Gender, nutritional status, and height had no significant association with psychosocial dysfunction and depression in children. Children with chronic disease were more likely to develop psychosocial dysfunction (OR 2.13; 95%CI 1.31 to 3.59; P<0.001) and depression (OR 2.57; 95%CI 1.04 to 7.62; P<0.03) compared with those who did not have chronic disease. Conclusion Children with chronic disease were more likely to develop psychosocial dysfunction and depression compared to those without a chronic disease. These results highlight the importance of mental health support in pediatric patients with chronic disease.
Safety and immunogenicity of the CoV2-Bio in a healthy population aged 18 years and older in Indonesia Maria, Suzy; Olfriani, Ciho; Koesnoe, Sukamto; Sekartini, Rini; Soedjatmiko; Medise, Bernie Endyarni; Yuniar, Irene; Indawati, Wahyuni; Wirahmadi, Angga; Sari, Rini Mulia; Adi, Nuri Purwito; Retnaningdyah, Windri
Medical Journal of Indonesia Vol. 34 No. 1 (2025): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247476

Abstract

BACKGROUND According to the WHO Target Product Profiles for COVID-19 Vaccines, vaccine development should be indicated for active immunization in all populations, in conjunction with other control measures to curtail the pandemic. Several RBD-based COVID-19 vaccines are being evaluated and have shown advantages. CoV2-Bio was developed based on the wild-type SARS-CoV-2 RBD amino acid sequence, representing residues of the spike protein of the Wuhan-Hu-1 isolate. This study aimed to evaluate the safety and immunogenicity of CoV2-Bio when compared to CoronaVac. METHODS This was an observer-blinded, randomized controlled prospective study of safety and immunogenicity of the CoV2-Bio in healthy adult population. A total of 54 healthy participants were randomized to receive either 3 doses of CoV2-Bio or 2 doses of CoronaVac, and 1 dose of placebo, administered 28 days apart. Participants were followed up for safety and immunogenicity. IgG antibody titers (ELISA) and neutralization assay against Wuhan and Delta strains were evaluated at baseline, Days 28, 56, and 84. We assessed seropositive rate, seroconversion, and GMT as parameters. RESULTS Both vaccines were well tolerated and induced good antibody response. The incidence rate and intensity of local and systemic adverse events did not differ between vaccine and control groups. The vaccine group showed a larger proportion of seroconversion (4-fold increase antibody) (87.5% versus 46.2%, p = 0.001) and higher GMT (305.9 AU/ml versus 102.4 AU/ml, p<0.001) when compared to control group. CONCLUSIONS 3 doses of the CoV2-Bio are safe and immunogenic in healthy adult population. 3 doses of the CoV2-Bio COVID-19 vaccine produce a better immunogenicity profile compared to CoronaVac.
Manfaat Terapi Pijat pada Anak Usia Prasekolah dengan Gangguan Pemusatan Perhatian/Hiperaktivitas Wirahmadi, Angga; Imanillah, Risa
Sari Pediatri Vol 27, No 3 (2025)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp27.3.2025.193-201

Abstract

Latar belakang. Tata laksana Gangguan Pemusatan Perhatian/Hiperaktivitas (GPPH) menggunakan pendekatan terapi multimodal sebagai standar, dimana klinisi menggabungkan terapi perilaku dengan farmakoterapi. Namun, farmakoterapi kurang direkomendasikan pada anak usia prasekolah. Terapi pijat pada anak dengan GPPH mulai dikembangkan di berbagai negara, sebagai salah satu terapi komplementer untuk memperbaiki gejala GPPH.Tujuan. Menilai efektivitas kombinasi terapi standar dan terapi pijat dibandingkan dengan terapi standar saja terhadap gejala GPPH.Metode. Penelusuran literatur melalui database elektronik PubMed, The Cochrane Library, Google Scholar, dan Scopus dengan kata kunci “massage”, “tuina”, “Attention Deficit Hyperactivity Disorder”, “children”, dan “pre-school”.Hasil. Kombinasi dengan terapi pijat dapat memperbaiki gejala GPPH dengan berbagai scoring yang tervalidasi pada anak usia prasekolah.Kesimpulan. Respons tehadap terapi pijat memiliki hasil yang bervariasi, namun tetap memiliki kemampuan untuk memperbaiki gejala GPPH pada anak usia prasekolah.
Co-Authors Annisa R. Yulman Araysi, Leo Alfath Bernie E. Medise Bernie Endyarni Medise Elizabeth Melina Harningtyas Jasmin Hartono Gunardi Hartono Gunardi Hartono Gunardi Imanillah, Risa Irene Yuniar, Irene Jasin, Madeleine Ramdhani Kuntjoro Harimurti Maria, Suzy Muhammad Aini Nuri Purwito Adi Olfriani, Ciho Resyana P. Nugraheni Retnaningdyah, Windri Rini Mulia Sari Rini Sekartini Rini Sekartini Rini Sekartini Saharso, Ersal Rasyid Soedjatmiko Soedjatmiko Soedjatmiko Soedjatmiko Soedjatmiko Soedjatmiko Soedjatmiko Sreshta Mukhi Sukamto Koesnoe Ufairah, Kamilia Rifani Wahyuni Indawati Wahyuni Indawati, Wahyuni Wangke, Lydia