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Journal : Paediatrica Indonesiana

Quality of life in children with chronic kidney disease Fibrianto, Ari; Lestari, Hertanti Indah; Kesuma, Yudianita; Damayanti, Moretta; Fitriana, Eka Intan; Rismarini, Rismarini
Paediatrica Indonesiana Vol. 63 No. 5 (2023): September 2023
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi63.5.2023.395-404

Abstract

Background Chronic kidney disease (CKD) has become a global burden on the healthcare system and significantly impacts the quality of life of children with the condition. Objective To assess quality of life in children with CKD as well as its relationship with sociodemographic, medical, and psychosocial factors. Methods This cross-sectional analytic study was conducted from June to November 2021 at Dr. Moh Hoesin Hospital, Palembang. Children with CKD aged 2–18 years were included by consecutive sampling. Parents and patients were asked to complete the PedsQL™ generic score scale version 4.0 questionnaire. Results We assessed quality of life in 112 children with CKD from parents’ and children’s reports in the PedsQL™ questionnaire. Physical and emotional parameters had the lowest scores. Based on parental reports, quality of life was significantly associated with disease severity (P=0.002), behavioral disorders (P=0.007), and sleep disturbances (P=0.001). Based on the children’s reports, the factors significantly associated with quality of life were anemia (P=0.044), sleep disturbances (P=0.024), and behavioral disorders (P=0.002). Almost one-third of children with CKD had general impairment of quality of life, both from parental reports (32.1%) and children’s reports (33.0%). Conclusion Disease severity, anemia, sleep disturbance, and behavioral disorders were all associated with poorer quality of life in children with CKD.
Prevalence and risk factors of depression in juvenile systemic lupus erythematosus Puspitanza, Ika Dian; Alia, Myrna; Kesuma, Yudianita; Rismarini, Rismarini; Novery, Edy; Bahar, Erial
Paediatrica Indonesiana Vol. 64 No. 4 (2024): July 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.4.2024.293-9

Abstract

Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems, including the central nervous system. Depression is one of the neuropsychiatric manifestations of juvenile SLE . Objective To estimate the prevalence of depressive disorders in juvenile SLE and identify its potential risk factors. Methods This cross-sectional study was conducted in juvenile SLE patients at Dr. Mohammad Hoesin General Hospital, Palembang. Sociodemographic data and medications were recorded. Disease activity of SLE was assessed using the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Physical activity was measured using the Physical Activity Questionnaire for Children (PAQ-C) and the Physical Activity Questionnaire for Adolescents (PAQ-A). All subjects were screened for depression using the Childhood Depression Inventory (CDI) questionnaire. Multiple linear regression analyses were used to determine risk factors for depressive disorders. Results We included 72 patients, of whom 67 (93.1%) were female. Mean age of the patients was 12 years 4 months (SD 2 years 6 months); most (67; 93.1%) were 10-18 years of age. Depression was found in 24 patients (33.3%). SLEDAI scores of ?3 (flare) were found in 54 patients (75%) and low physical activity was found in 62 (86.1%) patients. The prevalence of depression based on the Children's Depression Inventory was 33.3%. A SLEDAI score of ?3 and low physical activity were significantly associated with depression (P=0.009 and P=0.025, respectively). On multiple linear regression analysis, only SLEDAI score of ?3 remained significantly associated with depression (P= 0.017; OR 12.6; 95%CI 1.6–101.7). Gender, age, family economic status, father's education, mother's education, family history of depression, and duration of illness were not associated with depression. Conclusion A SLEDAI score indicating flare (?3) and low physical activity are significantly associated with an increased risk of depression. A SLEDAI score is an independent risk factor for depression when all other significant risk factors are considered.
Rate of administration of tuberculosis preventive treatment to pediatric household contacts and influencing factors Ridwan, Ivani; Sofiah, Fifi; Rismarini, Rismarini
Paediatrica Indonesiana Vol. 65 No. 5 (2025): September 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.5.2025.422-30

Abstract

Background Providing tuberculosis preventive treatment (TPT) to household contacts is an important measure for preventing disease transmission. Various child-, parent-, and healthcare-related factors influence TPT provision. Objective To determine the rate of pediatric TPT administration in household contacts of pulmonary TB patients and its influencing factors. Methods An observational analytical study was conducted from May-August 2024 at primary healthcare facilities in Palembang, Indonesia. We included children in household contact with bacteriologically-positive pulmonary TB patients confirmed by molecular rapid diagnostic test  who were registered for treatment in community health centers in Palembang that had a TB treatment program. Results Among 364 household contacts of 114 TB cases, only 3.3% received TPT. The majority of parents or guardians were <35 years of age, were biological parents of the included children, had sub-minimum wage incomes, demonstrated good understanding of TPT, and had completed at least secondary education. The majority of children were female, over 5 years of age, and well-nourished according to parent or caregiver subjective perception. At the participating community health centers, healthcare workers in charge of the TB treatment programs were mostly paramedical staff and had good TPT knowledge, and drug availability was adequate. Children with caregivers aged ≥35 years were 12 times more likely not to receive TPT (aOR=12,093; 95%CI 1,544 to 94,713; P=0.018). Caregiver role in the family, economic status, knowledge level, education, travel distance, child factors, and health facility factors showed no significant association with TPT provision. Conclusion The rate of TPT provision in Palembang is low, far below the national target of 50-90%. Guardian age of ≤35 years was the only factor significantly associated with TPT provision.