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All Journal JURNAL GIZI INDONESIA Journal of Biomedicine and Translational Research Medica Hospitalia Diponegoro International Medical Journal (DIMJ) Ophthalmologica Indonesiana

Arief Wildan, Arief

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Author-ID : 602855

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Dry Eyes Syndrome pada Penderita Diabetes Melitus Tipe 2 Setyorini, Desti Putri; Wildan, Arief; Nugroho, Trilaksana; Julianti, Hari Peni; HS, Heri-Nugroho
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 3 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

BACKGROUND : Type 2 diabetes mellitus patients have risk to suffer from dry eyes syndrome (DES), caused by peripheral and autonomic neuropathy, oxidative stress, and metabolic dysfunction. DES can reduce the patient’s quality of life then it could induce blindness if the patient didn’t get any therapy for DES. It is important to prevent DES by controlling its risk factors. OBJECTIVE : To investigate risk factors of DES in patients with type 2 diabetes mellitus. METHOD : . This study was an analytical observational study with cross-sectional design and purposive sampling. Subjects were examined by using questionnaire and slit lamp, then followed by deep interview in some subjects. This study was also using subject’s medical record to complete the required data. Subjects were diagnosed to suffer DES if OSDI score >12 and schirmer score <10mm. Data was analyzed by using statistic software. RESULT : . From 42 subjects, 19 subjects (45,2%) suffered from DES whereas another 23 subjects (54,8%) didn’t. There was significant relation between diabetic retinopathy (p=0.009) and DES in patients with type 2 diabetes mellitus showed by p value under 0,05 (OR 5.700, 95% CI:1.364-23.821). However, age (p=0.516), gender (p=1.000), level of knowledge (p=0.555), accessibility to health provider (p=1.000), occupation (p=0.644), economic level (p=0.105), smoke exposure (p=0.432), duration of diabetic (p=0.707), diabetic controlling (p=0.305), and history of dyslipidemia (p=0.155) had no significant relations with DES in patients with type 2 diabetes mellitus. CONCLUSION : There is a significant relation between diabetic retinopathy and DES in patients with type 2 diabetes mellitus. Diabetic retinopathy is the most dominant risk factor among the other factors in this study.

Berbagai Faktor Risiko Retinopati Diabetik pada Penderita Diabetes Melitus Tipe 2 Nafia, Nisa Khoirun; Nugroho, Trilaksana; Wildan, Arief; Julianti, Hari Peni; Purnomo, Hery Djagat
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 3 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

BACKGROUND: More than 75% of people with type 2 DM will anguish diabetic retinopathy 20 years after being diagnosed. However, the current changing of people’s lifestyle contributes to the tendency in type 2 DM that diagnosed at a younger age. This causes diabetic retinopathy can be occurred earlier and blindness will occur more quickly. It is important to prevent diabetic retinopathy by controlling some associated factors. OBJECTIVE: To investigate associated factors of diabetic retinopathy in people with type 2 DM. METHOD: Analytic observational study with cross-sectional design. Subjects were determined by purposive sampling. The subjects were interviewed using a questionnaire meanwhile, funduscopic examination is aimed to assess diabetic retinopathy and followed by deep interview. This study also used the subject’s medical record to complete the required data. The results were analyzed by using statistic software. RESULT: From 43 subjects, there wes no significant relation among age (p=0.965), gender (p=0.437), level of knowledge (p=0.640), accessibility (p=1.000), economic level (p=0.680), duration of DM (p=0.477), history of hypertension (p=0.708), and history of dyslipidemia (p=0.244) with diabetic retinopathy in people with type 2 DM. However, there was significant relation among controlling blood glucose (p=0.014) with diabetic retinopathy in people with type 2 DM. Uncontrolled blood glucose was 13 times more affected in diabetic retinopathy than controlled blood glucose (OR 13.417, 95% CI:1.474-122.117). CONCLUSION: There was a significant relation between controlling blood glucose and diabetic retinopathy in people with type 2 DM. Controlling blood glucose is the most dominant risk factor among the other factors in this study. Keywords: diabetic retinopathy; risk factor; type 2 diabetes mellitus

Co-Authors Andreas Tigor Partomuan, Andreas Tigor Astuti, Ratih Kusuma Dharma, Andhika Guna Dwi Retnoningrum Fifin Luthfia Rahmi Hari Peni Julianti Hermawan Istiadi Hery Djagat Purnomo HS, Heri-Nugroho Kingwijati, Syahriza Naufal Luthfinnisa, Fryta Ameilia Maharani Maharani Maharani, Maharani Mazidah Zulfa Nafia, Nisa Khoirun Nugroho, Trilaksana P, Satya Hutama Puspasari, Denti Rahmi, Fifin L Rikiandraswida, Zahira Riski Prihatningtias, Riski Ryamizard, Rizal Setyorini, Desti Putri Syahruzad, Rosa Uyun, Fuadah Widyawati, Syska Wulansari, Arin

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