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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Canopy: Journal of Architecture Molecular and Cellular Biomedical Sciences (MCBS) AL-IDARAH: JURNAL KEPENDIDIKAN ISLAM Prosiding Temu Profesi Tahunan PERHAPI Jurnal Kefarmasian Indonesia
Siti Nur Arifah, Siti Nur
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Dentistry Education Environmental Science Immunology & microbiology Medicine & Pharmacology Neuroscience

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KIDS ART STUDIO DI KOTA SEMARANG PENEKANAN DESAIN FUNGSI RUANG DAN SIRKULASI DENGAN PENDEKATAN TRANSFORMASI BENTUK GEOMETRIS Arifah, Siti Nur
Canopy: Journal of Architecture Vol 4 No 2 (2015): Canopy
Publisher : Canopy: Journal of Architecture

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Abstract

Kids Art Studio adalah suatu sekolah seni nonformal untuk anak-anak. Dengan mengajarkan seni rupa, musik, dan tari dengan sasaran untuk anak-anak dari kalangan menengah keatas. Pada saat ini anak banyak bermain gadget dari pada main bersama temannya dan membuat perkembangan otak dan kemampuan sensor dan motorik tidak terlatih dengan sempurna. Maka perlunya adanya pendidikan untuk dapat membantu perkembangan anak salah satunya dengan belajar seni sambil bermain.Semarang adalah salah satu kota terbesar di Indonesia yang memiliki pendududuk yang cukup banyak dengan jumlah penduduk 1,762,939 jiwa. Dengan adanya sebuah wadah pembelajari seni yang efektif diharapkan dapat mengapresiasi seni masyarakat, yang nantinya potensi-potensi dari generasi muda di bidang seni ini mampu memunculkan sifat-sifat khas dan kharateristik yang bermutu. Maka perlu adanya sekolah seni untuk anak untuk dapat mengasah kemampuan dalam bidang seni sesuai dengan kemampuan anak sesuai dengan usia salah satunya dengan Kids Art Studio. Tujuan adanya Kids Art Studio adalah sebagai sarana edukasi dan memfasilitasi media pembelajaran pendidikan seni untuk anak-anak dari keluarga menengah keatas, serta meningkatkan daya tarik anak-anak dari keluarga menengah keatas terhadap pendidikan seni.Konsep yang diangkat dalam perancangan dan perencanaan Kids Art Studio di Kota Semarang dapat menampung kegiatan pendidikan seni seperti seni lukis, musik dan tari dalam 1 bangunan dengan penekanan desain fungsi ruang dan sirkulasi dengan pendekatan transformasi bentuk geometris.
The Role of Black Soybean and Purple Sweet Potato Active Compound on Advanced Glycation End-Product in Streptozotocin-Induced Type 2 Diabetes Mellitus Rat Gofur, Abdul; Arifah, Siti Nur; Annisa, Yuslinda; Witjoro, Agung; Atho'illah, Mochammad Fitri; Lestari, Sri Rahayu
Journal of Tropical Life Science Vol 9, No 2 (2019)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.09.02.02

Abstract

Diabetic nephropathy is one of the diabetes complications attacking kidney leading to kidney damage. Hyperglycemia accompanying DM causes the increase of Ad-vanced Glycation End-Product (AGE) and Receptor Advanced Glycation End-Product (RAGE) activity, then develop kidney damage and other diabetes compli-cations. The study aimed to investigate the effect of black soybean, purple sweet potato, or their combination on the expression of AGE, RAGE, and kidney necro-sis T2DM model rats. The rats were given with high-calorie diet for five weeks and then injected with a low dose of streptozotocin (30 m/kg Body Weight) in intraperitoneal. DM rats were divided into: normal, K- (T2DM), K+ (T2DM + glibenclamide 0.6 mg/kg body weight), P1 (T2DM + black soybean), P2 (T2DM + purple sweet potato), and P3-5 Combination 1-3 (T2DM + combination of black soybean and purple sweet potato in ratio of 1 : 3, 2 : 2, and 3 : 1). DM rats were then given the treatments for thirty days. The effect of black soybean, purple sweet potato, or the combination of both was evaluated through the expression of AGE, RAGE, and necrosis of renal tubules. The changes in renal tubules histological characteristics were evaluated using hematoxylin-eosin (HE) staining. Immuno-histochemistry analysis of renal tubules was to evaluate AGE-RAGE expression after the treatments. The research results indicated that there was a significant dif-ference from the combination of black soybean and purple sweet potato in reduc-ing AGE, RAGE, and renal tubules necrosis. The BSB and PSP combination ratio of 1:1 was able to improve renal tubules, decrease the expression of AGE and RAGE towards near normal. The combination of black soybean and purple sweet potato could be used as one of the alternatives to improve kidney damage in dia-betic nephropathy.
Green Tea Yoghurt with Encapsulated Lacticaseibacillus paracasei E1 Improves Hepatocyte Damage in High-Fat High-Fructose Diet Mice by Reducing MDA and Increasing SOD Fadlilah, Dawama Nur; Izati, Rahmi; Al Faizah, Belinda Nabiila; Kavitarna, Septhyanti Aprilia; Ardiansyah, Esha; Sa'adah, Nur Alfi Maghfirotus; Atho'illah, Mochammad Fitri; Arifah, Siti Nur; Soewondo, Aris; Jatmiko, Yoga Dwi; Wardhani, Shinta Oktya; Barlianto, Wisnu; Rifa'i, Muhaimin
Molecular and Cellular Biomedical Sciences Vol 8, No 3 (2024)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v8i3.501

Abstract

Background: Obesity is a global epidemic caused by excessive body fat, which is increasing free fatty acids in the liver, causing oxidative stress and liver cell damage. Green tea yogurt (GTY) with encapsulated Lacticaseibacillus paracasei E1 (GTY-LpE1) might have a beneficial effect in reducing liver cell damage. This study was conducted determine GTY-LpE1 effect on superoxide dismutase (SOD) expression, malondialdehyde (MDA) expression and liver histopathology in high-fat high-fructose diet (HFFD) mice. Material and Methods: A completely randomized design (CRD) with 7 groups, including normal diet (ND) group, HFFD group, 1.3 mg/kg BW simvastatin (SIM)-administered HFFD group, 5 g/kg BW probiotic yoghurt (PY)-administered HFFD (PY), 2.5 g/kg BW GTY-administered HFFD (2.5 GTY), 5 g/kg BW GTY-administered HFFD (5 GTY), and 10 g/kg BW GTY-administered HFFD (10 GTY). The diet was given for 16 weeks, followed by oral administration of sim/yoghurt during the last 4 weeks. Mice were sacrificed and the liver was collected. SOD and MDA expression were analyzed by flow cytometry. Histopathology analysis was done by evaluating hematoxylin-eosin (HE) staining of the liver.Result: The percentage of necrotic cells were 34.55, 34.31, and 21.95%, when treated with 2.5, 5, and 10 g/kg BW with GTY-administered HFFD, respectively, these were lower than the ones in the HFFD group (69.49%). The percentage of MDA expression were 15.55, 18.69, and 22.42%, respectively, these were lower than the ones in the HFFD group as well. The percentage of SOD expression were 9.49, 7.85, and 11.11%, respectively, these were higher than the ones in the HFFD group (3.44%). Conclusion: GTY-LpE1 could decrease the number of necrotic cells in the HFFD mice livers and improve the hepatocyte damage by reducing MDA expression and enhancing SOD expression. GTY-LpE1 can be used as an alternative food to control obesity.Keywords: alginate, chitosan, encapsulation, green tea, probiotic
REDUKSI ORE LOSS MATERIAL DENGAN METODE PEMASANGAN TAIL GATE PADA TRUCK ADT PADA KEGIATAN PENGANGKUTAN ORE KE CRUSHER DI PT AGINCOURT RESOURCES Tambunan, Aris; Widhiyanto, Komang; Arifah, Siti Nur
Prosiding Temu Profesi Tahunan PERHAPI 2023: PROSIDING TEMU PROFESI TAHUNAN PERHAPI
Publisher : PERHAPI

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Abstract

Dalam sistem penambangannya PT Agincourt Resource mengunakan truk ADT (articulated dump truck) Volvo A60H payload 55 Ton (handbook) untuk pengangkutan ore waste material ke tempat pabrik penghancur (crusher plant) dan tempat penimbunan. Seiring dengan kegiatan pengangkutan pada masing-masing Pit, yaitu Pit Purnama, Pit Barani, dan Pit Ramba Joring terdapat materal tumpahan akibat proses pengangkutan pada jalan angkut yang memiliki kemiringan dan jalan tikungan. Material tumpahan dari truk ADT ini akan berpotensi mengakibatkan pengurangan jumlah volume material yang akan diperoleh, sehingga menurunkan jumlah ore yang akan diolah oleh pabrik pengolahan. Tercatat sudah payload actual selalu dibawah 55ton material waste dan ore dari ketiga pit yang merupakan material tumpahan pada bulan January 2022. Agar dapat mengurangi tumpahan material akibat pengangkutan, PT Agincourt Resources mengimplementasikan perubahan dengan memasang pintu belakang bak truk (tailgate) ADT Volvo A60H pada kegiatan pengangkutan. Dengan implementasi pemasangan tailgate tersebut diperoleh mengurangi ore spillage sebesar ± 0.6 ton per ritase. Hal ini tentunya juga akan sebanding dengan kenaikan recovery ore sebesar ± 0.5%.
Green Tea Yogurt Supplemented with L. paracasei E1 Microcapsules Increases Erythrocyte Counts and B Cell Development in High-Fat Fructose Diet Mice Sa'adah, Nur Alfi Maghfirotus; Ardiansyah, Esha; Fadlilah, Dawama Nur; Izati, Rahmi; Al-Faizah, Belinda Nabiila; Kavitarna, Septhyanti Aprilia; Atho’illah, Mochammad Fitri; Arifah, Siti Nur; Jatmiko, Yoga Dwi; Tsuboi, Hideo; Rifa'i, Muhaimin
Molecular and Cellular Biomedical Sciences Vol 9, No 1 (2025)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v9i1.573

Abstract

Background: Obesity-induced inflammation causes hematopoietic stress, disrupting bone marrow homeostasis. Green tea yogurt supplemented with Lacticaseibacillus paracasei E1 microcapsules (GTYP) is a promising way to overcome obesity due to its high antioxidant and anti-inflammatory activity. However, GTYP effects on blood production, specifically erythrocytes and B cells, remain unexplored.Materials and methods: Male Balb/C mice were fed either a high-fat fructose diet or a normal diet for 12 weeks. Microencapsulation was done by double coating of alginate-chitosan. There were seven groups in this study: normal diet (ND), high-fat fructose diet (HFFD), HFFD with 1.3 mg/kgBW Simvastatin (T1), HFFD with 5 g/kgBW plain yogurt (T2), HFFD with 2.5 g/kgBW GTYP (T3), HFFD with 5 g/kgBW GTYP (T4), and HFFD with 10 g/kgBW GTYP (T5). Erythrocyte counts from the peripheral blood were taken weekly. After 28 days of treatment, mice were sacrificed, bone marrow (BM) and lymphocytes were isolated. The cells of Ter119+, Ter119+CD59+, and B220+SDF-1+ were measured using flow cytometry.Results: HFFD not only reduces the peripheral erythrocyte count (2.15×109 cell/mL) but also affects the hematopoietic system, depleting Ter119+ (11.76%), TER119+CD59+ (0.050%), and B220+SDF-1+ (0.465%). Mice receiving 5 g/KgBW GTYP improved erythrocyte count (9.95×109 cells/mL). The parameters of erythrocyte and B cell development showed more remarkable improvement with GTYP treatment than simvastatin and plain yogurt (p<0.05). Molecular docking also indicated a great inhibitory effect of EGCG (-7.7) for the CXCR4 receptor.Conclusion: GTYP can potentially increase erythrocyte count and B cell development, particularly under obese conditions.   Keywords: anti-obesity, B lymphopoiesis, erythrocyte count, green tea yogurt, probiotics
Penerapan Program Literasi Pada Mata Pelajaran Pendidikan Agama Islam Di SMAN 4 Palangka Raya Syar, Nur Inayah; Arifah, Siti Nur; Normuslim, Normuslim
AL-IDARAH: JURNAL KEPENDIDIKAN ISLAM Vol 11 No 1 (2021): AL-IDARAH: JURNAL KEPENDIDIKAN ISLAM
Publisher : Universitas Islam Negeri Raden Intan Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24042/alidarah.v11i1.8574

Abstract

This research was conducted based on the Regulation of the Minister of Education and Culture Number 23 of 2015 concerning character development which is implemented in the School Literacy Movement. The purpose of this research is to describe the application of literacy in Islamic Religious Subject, explain information related to supporting factors, and inhibiting factors for the application of literacy at SMAN 4 Palangka Raya. This research is a descriptive qualitative research and the research subjects are teacher and students at SMAN 4 Palangka Raya. The results showed that the application of literacy in SMAN 4 Palangka Raya reached the second stage, namely the reading and writing stages. The application of literacy in SMAN 4 Palangka Raya is not in accordance with the guidelines in the GLN and GLNB manuals. This is because the books that are often used in literacy during PAI subjects are textbooks, whereas the appropriate books should be non-textbooks. The supporting factor for the application of literacy is the ability of teachers to utilize technology and learning media. The servant factors for the application of literacy are the lack of mentoring, the lack of availability of non-text books and the lack of student persistence and interest.
Probiotic-Green Tea Yoghurt on Improving Testicular Histology of High-fat and Fructose Diet Mice Izati, Rahmi; Al Faizah, Belinda Nabiila; Fadlilah, Dawama Nur; Kavitarna, Septhyanti Aprilia; Sa'adah, Nur Alfi Maghfirotus; Ardiansyah, Esha; Atho'illah, Mochammad Fitri; Arifah, Siti Nur; Rifa'i, Muhaimin; Jatmiko, Yoga Dwi; Rahayu, Sri
Jurnal Kefarmasian Indonesia VOLUME 14, NUMBER 2, AUGUST 2024
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

An unhealthy lifestyle can cause changes in the body's metabolism, leading to obesity. The development of obesity is supported by a disturbance in gut microbiota balance that triggers visceral fat deposition in organs such as the testes. Excess fat deposition triggers inflammation, dysfunction, and high ROS production that can damage testicular tissue. Yoghurt, a fermented milk product fortified with green tea, is high in antioxidants that can help reduce excess ROS. Adding encapsulated probiotics in yoghurt can stabilize the gut microbiota in obesity so that dysbiosis can be resolved. This study was conducted to determine the potential of green tea-probiotic yoghurt (GTY) on testicular tissue repair in mice fed a high-fat and fructose diet (HFFD). The research procedure includes feeding HFFD for 3 months, calculating the Lee index, lactic acid bacteria preparation, microencapsulated probiotics, yoghurt preparation, treatment, data collection, including relative weight of testes, the diameter of seminiferous tubules (DST), the epithelium thickness (ET), the number of Leydig cells (LC), and the number of spermatogenic cells. The mice groups were divided into normal (P0), HFFD (P1), HFFD + simvastatin 1.3 mg/Kg BW (P2), HFFD + plain yoghurt 5 g/Kg BW (P3), HFFD + GTY 2.5 g/Kg BW (P4), HFFD + GTY 5 g/Kg BW (P5), and HFFD + GTY 10 g/Kg BW (P6). The results showed that green tea infusion yoghurt with encapsulated probiotics could improve the structure of testicular tissue in mice after HFFD administration. The most effective dose is green tea yoghurt 5 g/Kg BW.
Co-Authors Abdul Gofur Agung Witjoro Al Faizah, Belinda Nabiila Al-Faizah, Belinda Nabiila Annisa, Yuslinda Ardiansyah, Esha Aris Soewondo Atho'illah, Mochammad Fitri Atho’illah, Mochammad Fitri Fadlilah, Dawama Nur Izati, Rahmi Kavitarna, Septhyanti Aprilia Normuslim Normuslim, Normuslim Rifa'i, Muhaimin Sa'adah, Nur Alfi Maghfirotus Shinta Oktya Wardhani, Shinta Oktya SRI RAHAYU Sri Rahayu Lestari Syar, Nur Inayah Tambunan, Aris Tsuboi, Hideo Widhiyanto, Komang Wisnu Barlianto YOGA DWI JATMIKO