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Research trends in brain imaging of mild cognitive impairment in 25 years: a bibliometric analysis Daniella Satyasari; Agnes Tineke Waney Rorong
Universa Medicina Vol. 42 No. 2 (2023)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2023.v42.214-226

Mild cognitive impairment (MCI) is a condition that is experienced by most elderly in the world. Although there has been a huge rise in research on developing brain imaging tests that can identify and evaluate MCI early on, a bibliometric analysis of this issue is still lacking. The purpose of this review is to determine the pattern and growth of research trends related to MCI and brain imaging using bibliometric analysis, based on Scopus data from 1996 to 2021. The data was converted to Comma Separated Values (CSV) and exported to VOSviewer to bibliometrically analyze the origin by country, keywords, frequently cited articles, author, and journals. Over a 25-year period, 5081 articles were discovered, with the number rising, particularly in the past four years, and significantly in 2022 when 561 articles (11.04%) were found. The Journal of Alzheimer's Disease (19.22%) and Neuroimage Clinical (10.22%) published the largest number of articles on this subject. The United States (24.31%) led all other countries in the number of publications, followed by China (14.84%) and UK (6.5%). The most cited article was by Petersen RC in 1999 (41 citations) about MCI and its clinical characterization. The keywords that appeared the most frequently were mild cognitive impairment (984 occurrences) associated with biomarkers, brain scanning procedures, brain part, age, and human subject. The most frequently cited authors were Petersen RC (1365 citations) and Jack CR (1103 citations). Neuroimage (4164 citations), and Neurology (3268 citations) are the most repeatedly cited journals. This bibliometric study displays the trend in the last 25 years for MCI and brain imaging.

Hubungan Kadar Karbon Monoksida dengan Gambaran Psikopatologi dan Kognitif pada Pengemudi Ojek Online Agnes Tineke Waney Rorong; Rivo Mario Warouw Lintuuran; Dyani Pitra Velyani; Daniella Satyasari; Ika Nur Fitriana
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 02 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i02.103

Keterpaparan bahan bakar bensin, di antaranya karbon-monoksida (CO) dalam jangka panjang merupakan konsekuensi kerja pengemudi ojek online (ojol). Afinitas tinggi CO dengan hemoglobin (COHb) berpotensi toksik terhadap kesehatan. Risiko gangguan jiwa meliputi depresi, cemas, somatoform dan kognisi. Penelitian ini bertujuan menilai hubungan kadar CO dengan psikopatologi dan kognisi pada pengemudi ojek online. Metode penelitian ini menggunakan desain potong lintang dengan populasi target supir ojek online Jabodetabek bertempat di kampus B Universitas Trisakti Jakarta. Pengukuran gambaran psikopatologi menggunakan kuesioner SRQ-20, kognisi dengan MMSE dan COHb (kadar tinggi ³ 3,5%). Hasil menunjukkan 123 responden dengan rerata usia 37,2 tahun; gender laki-laki 80,5%; pendidikan SMA 74%; pendapatan bulanan <= Rp. 4,9 juta (94,3%). Kadar COHb laki-laki 0,8x lebih tinggi dibanding perempuan yang seluruhnya normal. Terdapat hubungan signifikan antara gender dan kadar COHb (p=0,029), dan antara kadar COHb dengan masa kerja > 5 tahun (p=0,029). Tidak terdapat hubungan signifikan antara fungsi kognitif dan kadar COHb. Gambaran psikopatologi sebanyak 26,8% namun tidak terdapat hubungan dengan kadar COHb (p=0,778). Penelitian berikutnya direkomendasikan untuk melihat faktor-faktor lain yang dapat memberi kontribusi pada psikologi dan kognitif pengemudi ojek online.

PSIKOEDUKASI TENTANG EKSPRESI EMOSI PADA PELAKU RAWAT LANSIA DENGAN DEPRESI PASCA STROKE Lintuuran, Rivo Mario Warouw; Rorong, Agnes Tineke Waney; Satyasari, Daniella; Syafita, Arvia; Kogoya, Alvionita; Hartono, Adinda Mozart Rahmadhina Riyandi; Zachrani, Aliviannisa Hasmah; Suyanto, Alysa Naila Putri; Puteri, Amara Alifia; Kusharianto, Andhika Arief
Jurnal Pengabdian Masyarakat Trimedika Vol. 1 No. 1 (2024)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v1i1.19030

Post-stroke depression may worsen the wellbeing of elderly with stroke. Depression in elderly may be contributed by psychosocial factors including emotional expression in the family or caregiver. Objective: To identify and manage post-stroke depression in elderly and caregiver emotional expression which may impact patient’s physical and mental health. Methods: Data collection was taken at Krendang by means of visiting patient’s home and conducting interview, observation, and physical/mental examination. Results: A 63-year-old woman post stroke one year ago, was found with hypertension and left hemiparesis. Clinical and psychometric evaluations (Geriatric Depression Scale score 8, Abbreviated Mental Test score 7) yielded depression and decline cognitive function. Psychosocial issues revealed high emotional expression and anxiety in caregiver. Psychoeducation on physical and mental condition was provided to patient and family, especially in controlling emotional expression in caregiver. Conclusion: Psychoeducation on emotional expression and its management may help increase patient and caregiver’s quality of life.

PENYULUHAN DAN PELATIHAN FUNGSI KOGNITIF PADA LANSIA DI KELURAHAN KRENDANG, JAKARTA BARAT Dwiputri, Xena Aura; Fadhlan, Muhammad; Sulaiman, Zahra Annisya Putri; Suyatno, Nuraeni Aprilia Ningsih; Rorong, Agnes Tineke Waney; Lintuuran, Rivo Mario Warouw; Velyani, Dyani Pitra; Satyasari, Daniella; Fitriana, Ika Nur
Jurnal Pengabdian Masyarakat Trimedika Vol. 1 No. 2 (2024)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/

Lansia dapat mengalami penurunan fungsi kognitif seiring dengan bertambahnya usia dan pengaruh faktor-faktor medis dan non medis. Salah satu masalah yang dapat terjadi adalah munculnya kepikunan dan gangguan seperti demensia Alzheimer jika tidak dicegah. Tujuan: Meningkatkan pengetahuan dan kesadaran tentang pentingnya menjaga fungsi kognitif guna mencegah kepikunan atau demensia Alzheimer. Metode: Kegiatan dilakukan di Kelurahan Krendang terhadap 38 lansia. Penilaian pengetahuan lansia dilakukan dalam bentuk pre-test sebelum penyuluhan dan pelatihan, maupun post-test setelah penyuluhan dan pelatihan. Hasil: Penyampaian edukasi tentang fungsi kognitif kepada lansia dapat meningkatan pengetahuan khususnya dalam mengenali apa saja fungsi kognitif tersebut dan faktor-faktor yang memengaruhi seseorang bisa sehat maupun memiliki masalah kognitif. Terdapat peningkatan rata-rata skor tes 2,76 (dari total 5, sebelum pelatihan) ke 3,18 (sesudah) pelatihan dengan kenaikan 15,64% nilai tes. Sejumlah 34,21% mengalami peningkatan skor setelah dilakukan penyampaian informasi mengenai fungsi kognitif Kesimpulan: Penyuluhan dan pelatihan fungsi kognitif pada lansia terbukti meningkatkan pengetahuan yang dapat berujung pada pemeliharaan maupun perbaikan fungsi kognitif mereka, termasuk menurunkan risiko terjadinya demensia Alzheimer.

Memahami Perbedaan antara Apheresis, Plasmapharesis, dan Pertukaran Plasma: Urgensi Memahami Terminologi dalam Praktek Klinis Sehari-hari Mashabi, Yasmine; Rorong, Agnes Tineke Waney; Abdillah, Fauzan; Widowati, Henie
Jurnal Biomedika dan Kesehatan Vol 8 No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Apheresis is a modern technique that is relatively safe and more efficient compared to conventional methods in blood component collection. In this procedure, only specific components of the blood such as platelets, plasma, or red blood cells are collected, while the other blood components are returned to the donor's body. This approach allows for more focused donations and minimizes overall blood volume loss. Transfusions from apheresis results from a single donor have also been shown to reduce the risk of immunological reactions as well as decrease the likelihood of bacterial contamination. Now, in addition to being used as a blood collection method for donation purposes, apheresis is also increasingly widely applied as therapy for various medical conditions. The accuracy in medical terminology is a crucial element for clinical practice, directly contributes to the effectiveness of therapeutic interventions, patient safety, and the efficiency of communication among health professionals. Three terms that are often misinterpreted as synonyms but have substantial clinical differences are apheresis, plasmapheresis, and plasma exchange. Although all three are based on the principle of extracorporeal separation of blood components, each procedure has different indications, methods of execution, and therapeutic goals. This article aims to elaborate on the fundamental differences among these three terms while emphasizing the urgency of education and standardization of terminology in everyday health service practice.

Hubungan Kadar Karbon Monoksida dengan Gambaran Psikopatologi dan Kognitif pada Pengemudi Ojek Online Rorong, Agnes Tineke Waney; Lintuuran, Rivo Mario Warouw; Velyani, Dyani Pitra; Satyasari, Daniella; Fitriana, Ika Nur
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 02 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i02.103

Keterpaparan bahan bakar bensin, di antaranya karbon-monoksida (CO) dalam jangka panjang merupakan konsekuensi kerja pengemudi ojek online (ojol). Afinitas tinggi CO dengan hemoglobin (COHb) berpotensi toksik terhadap kesehatan. Risiko gangguan jiwa meliputi depresi, cemas, somatoform dan kognisi. Penelitian ini bertujuan menilai hubungan kadar CO dengan psikopatologi dan kognisi pada pengemudi ojek online. Metode penelitian ini menggunakan desain potong lintang dengan populasi target supir ojek online Jabodetabek bertempat di kampus B Universitas Trisakti Jakarta. Pengukuran gambaran psikopatologi menggunakan kuesioner SRQ-20, kognisi dengan MMSE dan COHb (kadar tinggi ³ 3,5%). Hasil menunjukkan 123 responden dengan rerata usia 37,2 tahun; gender laki-laki 80,5%; pendidikan SMA 74%; pendapatan bulanan <= Rp. 4,9 juta (94,3%). Kadar COHb laki-laki 0,8x lebih tinggi dibanding perempuan yang seluruhnya normal. Terdapat hubungan signifikan antara gender dan kadar COHb (p=0,029), dan antara kadar COHb dengan masa kerja > 5 tahun (p=0,029). Tidak terdapat hubungan signifikan antara fungsi kognitif dan kadar COHb. Gambaran psikopatologi sebanyak 26,8% namun tidak terdapat hubungan dengan kadar COHb (p=0,778). Penelitian berikutnya direkomendasikan untuk melihat faktor-faktor lain yang dapat memberi kontribusi pada psikologi dan kognitif pengemudi ojek online.

Hubungan Kapasitas Cadangan Kognitif dan Kualitas Hidup Lansia Rorong, Agnes Tineke Waney; Lintuuran, Rivo Mario Warouw; Velyani, Dyani Pitra; Satyasari, Daniella; Fitriana, Ika Nur
Jurnal Locus Penelitian dan Pengabdian Vol. 5 No. 1 (2026): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v5i1.5424

The elderly are vulnerable to geriatric problems or syndromes, including cognitive impairment that can progress to dementia, leading to a decreased quality of life. One factor that can prevent cognitive problems or impairment in the elderly is cognitive reserve capacity, the brain's ability to optimize its function and prevent damage that can affect cognition. This study aims to analyze the relationship between cognitive reserve capacity and quality of life in the elderly. A cross-sectional study was conducted on 109 elderly in Krendang Village, West Jakarta, in February 2024. Inclusion criteria included elderly aged 60-79 years who were able to read, write, and communicate in Indonesian, were in good health or had controlled medical conditions, and were able to hear and see well. The variables studied were cognitive reserve capacity (education and employment, neuroprotection, physical health risk factors, and mental health risk factors) and quality of life, as assessed by the WHOQoL-BREF instrument. Bivariate analysis was performed using the Pearson correlation test to determine the correlation between cognitive reserve capacity and quality of life. Multivariate analysis using linear regression was performed to identify factors in cognitive reserve capacity that significantly influence quality of life. A total of 109 subjects (mean age 66.2 years with a standard deviation of 4.59) participated in this study. The mean total cognitive reserve capacity score was 41.42 ± 6.79. The mean quality of life scores for the physical domain was 14.61 ± 2.41; the psychological domain 13.08 ± 1.93; the social relationships domain 13.19 ± 2.59; and the environmental domain 14.14 ± 1.97. Sociodemographic factors significantly associated with quality of life included gender, education, family residence, and financial resources. There was a significant correlation between cognitive reserve capacity and quality of life (p<0.05), with moderate correlations in the physical domain (r=0.42) and social relationships (r=0.42), and weak correlations in the psychological domain (r=0.26) and environmental domain (r=0.26). The R2 value was 14.5%. Cognitive reserve capacity is associated with quality of life in older adults, particularly in the physical domain and social relationships.

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